Siebert R, Puchta H. Efficient repair of genomic double-strand breaks by homologous recombination between directly repeated sequences in the plant genome. (wikipedia.org)
An increase number of repeats of a genomic, tandemly repeated DNA sequence from one generation to the next. (uams.edu)
Tandem sequences1
Thus direct repeat tandem sequences are a form of microsattelite DNA. (wikipedia.org)
Genomes1
of tandem repeats within their genomes [6, 17]. (scirp.org)
Genome3
In other words, the direct repeats are nucleotide sequences present in multiple copies in the genome. (wikipedia.org)
There are several types of repeated sequences : Interspersed (or dispersed) DNA repeats (interspersed repetitive sequences) are copies of transposable elements interspersed throughout the genome. (wikipedia.org)
In directly repeated sequences of the tobacco plant genome, DNA double-strand breaks can be efficiently repaired by homologous recombination between the repeated sequences. (wikipedia.org)
Sequences2
Flanking (or terminal) repeats (terminal repeat sequences) are sequences that are repeated on both ends of a sequence, for example, the long terminal repeats (LTRs) on retroviruses. (wikipedia.org)
The process of DNA mismatch repair plays a prominent role in the formation of direct trinucleotide repeat expansions. (wikipedia.org)
Motif1
A tract of repetitive DNA in which a motif of a few base pairs is tandemly repeated numerous times (e.g. 5 to 50 times) is referred to as microsatellite DNA. (wikipedia.org)
The SSRs were categorized for the numbers of repeats present, their overall length and were allocated to their linkage group. (researchgate.net)
A total of 4,761 perfect and 6,583 imperfect SSRs were present in 3,781 genes (14.11% of the total), corresponding to an overall density across the gene space of 32,5 and 44,9 SSRs/Mbp for perfect and imperfect motifs, respectively. (researchgate.net)
Specific1
Direct repeats are a type of genetic sequence that consists of two or more repeats of a specific sequence. (wikipedia.org)
Total1
This graph shows the total number of publications written about "DNA Repeat Expansion" by people in UAMS Profiles by year, and whether "DNA Repeat Expansion" was a major or minor topic of these publications. (uams.edu)
Written2
The nucleotide sequence written in bold characters signifies the repeated sequence. (wikipedia.org)
Below are the most recent publications written about "DNA Repeat Expansion" by people in Profiles over the past ten years. (uams.edu)
Pathogenic2
However, pathogenic loci bear expanded alleles of up to several hundred or even thousand repeats in severe cases. (bmj.com)
As with many other tandemly repeated microsatellite sequences, pathogenic TNRs are highly unstable in both the somatic and germ cell lineage, leading to expansions and contractions in the length of the repeats in successive cell or individual generations. (bmj.com)
Sequence7
Direct repeats are a type of genetic sequence that consists of two or more repeats of a specific sequence. (wikipedia.org)
Generally, a direct repeat occurs when a sequence is repeated with the same pattern downstream. (wikipedia.org)
The nucleotide sequence written in bold characters signifies the repeated sequence. (wikipedia.org)
Flanking (or terminal) repeats (terminal repeat sequences) are sequences that are repeated on both ends of a sequence, for example, the long terminal repeats (LTRs) on retroviruses. (wikipedia.org)
10 These factors are not mutually exclusive and include the purity and length of the repeated sequence, 7, 11 age of individuals, 6, 7 mitotic drive, 12 the relative position of the TNR with respect to adjacent origins of DNA replication, 13 and mutations in genes involved in DNA repair, replication, and recombination. (bmj.com)
We used simple sequence repeat (SSR) markers that could be transferred from Manihot esculenta (cassava) to analyze the genetic relationships among 45 accessions of J. curcas from our germplasm collection. (biomedcentral.com)
The traditional methods of developing simple sequence repeat (SSR) markers are usually time-consuming and labor-intensive. (biomedcentral.com)
Alleles2
In addition, much of the evidence for the mechanisms that are thought to produce repeat expansion in pathological TNRs are dismissed as irrelevant for normal alleles. (bmj.com)
Its molecular basis is an expansion of a CTG repeat in the 3′ untranslated region (UTR) of the DMPK gene on chromosome 19. (bmj.com)
Processes1
The 187 EST-SSRs resided in genes that are involved mainly in biological and metabolic processes. (biomedcentral.com)
Genetic1
6- 8 Expansions in the number of TNRs are known to be a molecular basis of genetic anticipation, 9 the progressively earlier age of onset of a disease with increasing severity in successive generations. (bmj.com)