• medulla
  • The adrenal medulla is located anatomically at the center of each adrenal gland, and is composed of neuroendocrine (chromaffin) cells which produce and release epinephrine (adrenaline) into the bloodstream in response to activation of the sympathetic nervous system. (wikipedia.org)
  • liver
  • An appropriate work-up at that time included a CT scan of the chest, abdomen, and pelvis and liver functions tests, all of which were negative for metastatic disease. (biomedcentral.com)
  • lungs
  • They frequently invade large vessels, such as the renal vein and inferior vena cava, as well as metastasizing via the lymphatics and through the blood to the lungs and other organs. (wikipedia.org)
  • epithelium
  • The tumour arises from the cells of the proximal renal tubular epithelium. (wikipedia.org)
  • This stratified squamous epithelium is maintained by cell division within the stratum basale, in which differentiating cells slowly displace outwards through the stratum spinosum to the stratum corneum, where cells are continually shed from the surface. (wikipedia.org)
  • glucocorticoids
  • Hypertension and hypokalemia can commonly be observed and are due to either aldosterone production (rare), secretion of mineralocorticoid precursors (11- deoxycorticosterone) or high levels of glucocorticoids overwhelming the renal 11-beta -HSD system leading to mineralocorticoid effects. (psychiatryadvisor.com)
  • proliferation
  • Her aspirate revealed a spindle cell proliferation devoid of mycobacteria that was immunoreactive for S-100 and macrophage markers (KP-1, PGM1). (pubmedcentralcanada.ca)
  • The demonstration of clonality is now considered to be necessary to identify a lymphoid cell proliferation as neoplastic. (wikipedia.org)
  • A neoplasm can be caused by an abnormal proliferation of tissues, which can be caused by genetic mutations. (wikipedia.org)
  • type
  • Intraepidermal squamous cell carcinoma, Bowen type (C44. (wikipedia.org)
  • Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. (wikipedia.org)
  • nuclei
  • Cytomorphologically, several overlapping features were observed between primary ACN and metastatic RCC, including: abundant clear cytoplasm, often with microvesicles, large nuclei with prominent nucleoli, bare nuclei, and prominent vascularity. (mysciencework.com)
  • large
  • Due to their location deep in the retroperitoneum, most adrenocortical carcinomas are not diagnosed until they have grown quite large. (wikipedia.org)
  • tissue
  • Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. (wikipedia.org)
  • The main cellular component of this tissue is the adipocyte, or fat cell. (wikipedia.org)
  • treatment
  • The Treg cells having a demethylated Foxp3 TSDR region can be used, for example for preparation of pharmaceutical compositions for use in treatment. (patents.com)
  • form
  • In the embryo, the epidermis, hair, and glands form from the ectoderm, which is chemically influenced by the underlying mesoderm that forms the dermis and subcutaneous tissues. (wikipedia.org)
  • system
  • Many conditions affect the human integumentary system-the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. (wikipedia.org)