• The genome contains multiple clusters of genes encoding proteins essential for survival in a nutrient-poor habitat. (wikipedia.org)
  • The central feature of the cell cycle regulation is a cyclical genetic circuit-a cell cycle engine-that is centered around the successive interactions of five master regulatory proteins: DnaA, GcrA, CtrA, SciP, and CcrM whose roles were worked out by the laboratories of Lucy Shapiro and Harley McAdams. (wikipedia.org)
  • The genetic determinants for the production of A/E lesions are located on the locus of enterocyte effacement (LEE) ( 4 ) , a pathogenicity island that contains the genes encoding intimin, a type III secretion system, a number of secreted (Esp) proteins, and the translocated intimin receptor named Tir ( 1 ) ( Figure 2 ). (cdc.gov)
  • Tir, which is one of the EPEC translocated proteins, is inserted into the host cell membrane, where it acts as a receptor to intimin ( 8 ) . (cdc.gov)
  • In addition to Vgr and Hcp proteins, the actual hallmark of this novel system is the presence of an AAA+ Clp-like ATPase and of two additional genes icmF and dotU , encoding homologs of T4SS stabilising proteins [ 10 ]. (biomedcentral.com)
  • Dashed boxes indicate the proteins that function in flagellar secretion, either in the membrane-bound part of the apparatus or in delivery of substrate. (nature.com)
  • Significant changes in gene expression of proteins that mediate oxidative metabolism, such as cytochrome d ubiquinol oxidase-encoding genes, cydA and cydB , were detected. (microbiologyresearch.org)
  • Finally, genes encoding putative regulatory proteins such as extracellular function (ECF) sigma factors as well as small proteins had elevated expression levels in the presence of oxygen. (microbiologyresearch.org)
  • Among these, genes encoding transport proteins as well as iron containing DszA like monooxygenases and TauD like dioxygenases were strongly overrepresented. (omicsdi.org)
  • Pigmented (Pgm+) cells of Yersinia pestis are virulent, are sensitive to pesticin, adsorb exogenous hemin at 26 degrees C (Hms+), produce iron-repressible outer membrane proteins, and grow at 37 degrees C in iron-deficient media. (omicsdi.org)
  • Materials and methods We used the Seed database (http://theseed.uchicago.edu/FIG/index.cgi) for chromosome alignment and phylogenetic analysis of gene Retigabine tyrosianse inhibitor positional clusters.18 The Compare Regions source provided by Seed allows alignment of chromosome loci that contain open reading frames for homologous proteins, or, quite simply, to pin these loci through genes that are homologous to a query sequence. (cancercurehere.com)
  • Bacterial siderophores are small molecules with unmatched capacity to scavenge iron from proteins and the extracellular milieu, where it mostly occurs as insoluble Fe 3+ . (biomedcentral.com)
  • Generally, the bacterial species that divides fastest will be most effective at exploiting resources and effectively occupying ecological niches. (wikipedia.org)
  • Ability to produce A/E lesions has also been detected in strains of Shiga toxin-producing E. coli (enterohemorrhagic E. coli [EHEC]) and in strains of other bacterial species (1). (cdc.gov)
  • The genes encoding T6SS have been reported a few years ago as being present in different bacterial species, although it was not clear at that time whether those genes act together or are important in bacteria-host interactions [ 7 ]. (biomedcentral.com)
  • Recent reports demonstrated the importance of T6SS in pathogenesis of several bacterial species. (biomedcentral.com)
  • The picture is si-milar in Vibrio - 'similar' refers to a great deal of protein homology among the numerous components in various species, despite vastly different regulatory circuits - for which the present model for competence involves 19+ genes, and, as core components: 1. (asmblog.org)
  • This system, causing the repression of the target gene in response to anhydrotetracycline (ATc), has been successfully used in several laboratories to characterize essential genes in different mycobacterial species both in vitro and in vivo. (omicsdi.org)
  • Orthologs are sequences of genes that evolved from a common ancestor and can be traced evolutionarily through different species. (pharmaceuticalintelligence.com)
  • This is the first report of any bacterial species possessing two genes for homologs of this major outer membrane protein. (shengsci.com)
  • This study shows the natural occurrence of serratiochelins, photobactin, enterobactin, and aerobactin in a single bacterial species and illuminates the interplay between siderophore biosynthetic pathways and polyamine production, indicating routes of molecular diversification. (biomedcentral.com)
  • Toxin-antitoxin (TA) genes were found in all three species: on the V. diabolicus fitness island, and on the V. parahaemolyticus and V. vulnificus PAIs. (springeropen.com)
  • Pathogenesis of both species is complex, and while some virulence factor genes have been implicated, the mechanisms underlying V. vulnificus and V. parahaemolyticus virulence are not well understood (Broberg et al. (springeropen.com)
  • The Caulobacter CB15 genome has 4,016,942 base pairs in a single circular chromosome encoding 3,767 genes. (wikipedia.org)
  • Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? (biomedcentral.com)
  • That's less than the estimated average number of genes acquired via HGT over time by a small bacterial genome of, say, 1,200 genes! (asmblog.org)
  • Genome-wide sequence analysis yielded a total of 286 predicted virulence factors, 178 resistance genes, 17 chaperone protein manipulators of fimbriae, 47 genes involved in the encoding of flagellin, 12 cell membrane-associated virulence genes, 18 Enterobacteriaceae common antigens, etc. (bvsalud.org)
  • Five Salmonella genome sequences, representing a broad host range serotype (Typhimurium), two host restricted serotypes (Typhi [two genomes] and Paratyphi) and one host adapted serotype (Choleraesuis) were used to identify core genome genes that show evidence for recombination and positive selection. (biomedcentral.com)
  • Our data show that, among the four serotypes analyzed, (i) less than 10% of Salmonella genes in the core genome show evidence for homologous recombination, (ii) a number of Salmonella genes are under positive selection, including genes that appear to contribute to virulence, and (iii) branch specific positive selection contributes to the evolution of host restricted Salmonella serotypes. (biomedcentral.com)
  • The annotation of the full genome sequence revealed the absence of genes encoding for a non-flagellar type 3 protein secretion system (NF-T3SS). (assignster.com)
  • Some average oncogenes are download the heritage genes, which can save called well with the presence N, for yield, the progression of genome from antitermination distribution and progeny from number. (scoutconnection.com)
  • All four islands had markedly different GC profiles than the rest of the genome, indicating that all of these islands were acquired via lateral gene transfer. (springeropen.com)
  • The genetic basis of the phenotypic differences between the two strains results from coding, regulatory, and insertion/deletion polymorphisms at five chromosomal loci. (wikipedia.org)
  • The EAF plasmid is not essential for the formation of A/E lesions, although its presence enhances their efficiency, probably through the influence of a cluster of plasmid-borne regulatory genes ( per A , B , C ) that increase expression of the chromosomal LEE genes ( 1 ) . (cdc.gov)
  • Fluorescence microscopy of chitin bead-co-lo-nizing cells of V. cholerae engineered to carry trans-lational fusions for the competen-ce protein ComEA-mCherry (red) and the T6SS sheath pro-tein VipA-sfGFP (green), both encod-ed at their native chromosomal locus. (asmblog.org)
  • PAIs are large chromosomal regions that are flanked by tRNA genes, and are usually associated with mobile genetic elements, such as phage, plasmid, integron, and transposon genes. (springeropen.com)
  • Diagram of the main genes of the locus of enterocyte effacement (LEE) region and the enteropathogenic Escherichia coli (EPEC) adherence factor (EAF) plasmid. (cdc.gov)
  • Also present in the EAF plasmid is the cluster of genes that encode bundle-forming pili (BFP), which interconnect bacteria within microcolonies and thus promote their stabilization ( 1 ) . (cdc.gov)
  • In this paper we demonstrated that the instability was mainly due either to the loss of the integrative plasmid carrying the genes encoding the two repressors, or to the selection of a frameshift mutation in the gene encoding the repressors Pip. (omicsdi.org)
  • One of the few antigens against which mammals develop protective immunity is the highly polymorphic OspC protein, encoded by the ospC gene on the cp26 plasmid. (cdc.gov)
  • The availability of hundreds of bacterial genomes allowed a comparative genomic study of the Type VI Secretion System (T6SS), recently discovered as being involved in pathogenesis. (biomedcentral.com)
  • CF27 exhibits a large number of genomic islands (mostly containing genes of unknown function), suggesting that a large number of genes has been acquired by horizontal gene transfer over time. (frontiersin.org)
  • In resistant individuals, we detected up-regulation of specific immune-related genes differentiating resistant individuals from controls at 96 hpi, which suggests a possible genomic basis of resistance, although no genetic variation in coding regions was found. (biomedcentral.com)
  • An A. salmonicida genomic DNA library was constructed by using lambda GEM-11 and recombinant phage carrying both genes ompAI and ompAII) selected by immunoscreening. (shengsci.com)
  • Pathogenicity islands (PAIs) are large genomic regions that contain virulence genes, which aid pathogens in establishing infections. (springeropen.com)
  • A genomic island must contain at least one virulence gene, or gene that contributes to pathogenesis, to be considered a PAI. (springeropen.com)
  • Flagellar assembly begins with structures in the cytoplasmic membrane and proceeds through steps that add the exterior structures in a proximal-to-distal sequence ( Fig. 1 ) 1 . (nature.com)
  • CM, cytoplasmic membrane. (nature.com)
  • The repeat units are built up at undecaprenylphosphate lipid carriers that are anchored in the cytoplasmic membrane. (caister.com)
  • To solve these problems, we (i) constructed a new integrative vector in which the gene encoding the integrase was deleted to increase its stability, and (ii) developed a new integrative vector carrying the gene encoding Pip to introduce a second copy of this gene in the chromosome. (omicsdi.org)
  • The typical graphic windows presents a selected number of chromosome loci from different genomes. (cancercurehere.com)
  • Lateral gene transfers resulted in different linkages between the ospC gene and loci of the chromosome or other plasmids. (cdc.gov)
  • However, only the hly, cnf, pap and iroN genes occurred significantly Selleck PD 332991 more frequently when comparing the strains from pregnant women (48) with those from nonpregnant women (38) (Table 2). (proteasomesignaling.com)
  • A 3.3-kilobase PvuII fragment carrying the PHR1 gene of Saccharomyces cerevisiae has been cloned into an Escherichia coli expression vector and introduced into E. coli strains deficient in DNA photolyase. (shengsci.com)
  • In addition, we sequenced 99 ospC flanking sequences from different lineages and compared the complete cp26 sequences of 11 strains as well as the cp26 bbb02 loci of 56 samples. (cdc.gov)
  • Over time, OspC genes were transferred between strains through recombinations involving the whole or parts of the gene and one or both flanks. (cdc.gov)
  • Sequencing and evolutionary analyses of four genes in an additional 42 isolates representing 23 serotypes confirmed branch specific positive selection and recombination patterns. (biomedcentral.com)
  • Consequently, we treated consistency of gene proximity in loci in evolutionary distant genomes as an indication of functional relatedness, which led to a prediction of SBDS protein involvement in initiation of translational wybutosine metabolism. (cancercurehere.com)
  • We demonstrate that not only the presence of pathogen inherent molecular patterns induces immune responses, but that bacterial motility is linked to a host-cell-induced expression of additional immune modulators. (elifesciences.org)
  • The opportunistic pathogen may infect virtually any tissue and has evolved as a model to study bacterial adaptation to the conditions within the human host. (elifesciences.org)
  • Chlamydia trachomatis is an obligate intracellular human pathogen that exhibits stage-specific gene transcription throughout a biphasic developmental cycle. (plos.org)
  • Here, we applied complementary omic approaches, including dual RNAseq and 16S rRNA gene metabarcoding sequencing using Nanopore and short-read Illumina technologies to unravel the host-pathogen interplay in an experimental infection system using the tropical fish Platax orbicularis as model. (biomedcentral.com)
  • Borrelia burgdorferi , an emerging bacterial pathogen, is maintained in nature by transmission from one vertebrate host to another by ticks. (cdc.gov)
  • By means of DNA sequencing of a large sample collection of the pathogen from across the United States, we studied the gene for the bacterium's highly diverse OspC protein, protective immunity against which develops in animals. (cdc.gov)
  • The present study investigated the effects of baicalin-aluminum on the virulence-associated traits and virulence genes expression of C. perfringens CVCC2030, it also evaluated the in vivo therapeutic effect on NE. (bvsalud.org)
  • This study suggests that baicalin-aluminum may be a potential candidate against C. perfringens infection by inhibiting the virulence-associated traits and virulence genes expression. (bvsalud.org)
  • Both PAIs contained virulence genes. (springeropen.com)
  • Overall, 3323 orthologous genes were identified in all 5 Salmonella genomes analyzed. (biomedcentral.com)
  • orthologs are proven as crimson arrows (N1) in the centers of all selected regions, to also find repetitive occurrence of shades/numbers depicting various other orthologous genes in various genomes. (cancercurehere.com)
  • The PAI found in V. parahaemolyticus contained the tdh gene, a collagenase gene, and genes involved in the type 3 secretion system II (T3SS2). (springeropen.com)
  • The central mechanism of EPEC pathogenesis is a lesion called attaching and effacing (A/E), which is characterized by microvilli destruction, intimate adherence of bacteria to the intestinal epithelium, pedestal formation, and aggregation of polarized actin and other elements of the cytoskeleton at sites of bacterial attachment ( Figure 1 ). (cdc.gov)
  • Intimin, a 94-kDa outer membrane protein encoded by the eae gene, is responsible for the intimate adherence between bacteria and enterocyte membranes. (cdc.gov)
  • In this pattern, bacteria bind to localized areas of the cell surface, forming compact microcolonies (bacterial clusters) that can be visualized after bacteria have been in contact with cells for 3 hours. (cdc.gov)
  • 176 T6SS loci (encompassing 92 different bacteria) were identified and their comparison revealed that T6SS-encoded genes have a specific conserved genetic organization. (biomedcentral.com)
  • Phylogenetic reconstruction based on the core genes showed that lateral transfer of the T6SS is probably its major way of dissemination among pathogenic and non-pathogenic bacteria. (biomedcentral.com)
  • Complex interactions between Gram-negative bacteria and their environment are facilitated by numerous surface-attached and exported macromolecules, some of which represent bacterial toxins and effectors. (biomedcentral.com)
  • In both Gram-positive and Gram-negative bacteria, 'competence' for DNA uptake requires the coordinated action of rough-ly two dozen genes ( including some with regulatory func-tions ) organized within several operons. (asmblog.org)
  • Tightly regulated gene expression systems represent invaluable tools for studying gene function and for the validation of drug targets in bacteria. (omicsdi.org)
  • 20%), including a number of genes with confirmed or likely roles in virulence and ompC , a gene encoding an outer membrane protein, which has also been found to be under positive selection in other bacteria. (biomedcentral.com)
  • The ligands include molecular patterns like lipopolysaccharides (LPS), which are the constituents of the outer membrane of gram negative bacteria. (fortunejournals.com)
  • Functionally related genes are commonly found clustered in prokaryotic and eukaryotic genomes,12C17 and predicting gene function based on physical proximity to other genes has been used successfully in a number of studies. (cancercurehere.com)
  • We utilized similarity, meaning that the genomes are selected utilizing the similarity of the chosen genes to its orthologs in various other genomes. (cancercurehere.com)
  • Such strategies implicitly presume that resistance leads to reduced bacterial fitness in an antibiotic-free environment, and therefore these resistant populations should be rapidly outcompeted by antibiotic-sensitive variants. (elifesciences.org)
  • Knocking out SchF0, an enzyme involved in the assembly of enterobactin alone, significantly reduced bacterial fitness. (biomedcentral.com)
  • There are currently 20 retinal genes whose mutations cause the phenotype of LCA, accounting for about 70% of the cases, while the genes underlying the remaining 30% of patients await discovery. (aao.org)
  • Visual acuity (VA) in children with LCA varies significantly among patients with differing gene mutations and can be as low as no light perception (NLP). (aao.org)
  • A way forward on how mutations of the SBDS gene (loci. (cancercurehere.com)
  • CF27-specific gene clusters which have been analyzed were expressed by both ferrous iron-grown and sulfur-attached cells, indicating that they are not pseudogenes and may play a role in both situations. (frontiersin.org)
  • We report that Serratia plymuthica V4 produces a variety of siderophores, which we term the siderome , and which are assembled by the concerted action of enzymes encoded in two independent gene clusters. (biomedcentral.com)
  • The enzymes encoded by one of the gene clusters can independently assemble enterobactin. (biomedcentral.com)
  • In the African meningitis belt, serogroup A of Neisseria meningitidis (NmA) is the most frequent cause of bacterial meningitis. (cdc.gov)
  • Campylobacters are the leading cause of bacterial foodborne gastroenteritis in the world. (assignster.com)
  • 22, 1637-1639 (1994) REFERENCE 10 AUTHORS Janosi,L., Shimizu,I. and Kaji,A. TITLE Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth JOURNAL Proc. (nig.ac.jp)
  • Iron is essential for bacterial survival. (biomedcentral.com)
  • Two homologs of the outer membrane protein OmpA were identified in Aeromonas salmonicida by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, immunoblotting, and amino-terminal sequence analyses. (shengsci.com)
  • The evolution of Salmonella Typhi towards a lifestyle characterized by systemic infection and transmission by excretion through the gall bladder rather than luminal gut colonization [ 4 ] involved a combination of acquisition events (e.g., acquisition of Vi capsule related genes), and deletion events (e.g., loss of virulence-associated genes, such as several genes in SPI-1, SPI-2, SPI-3, SPI-4 and SPI-5). (biomedcentral.com)
  • Included are those involved in chemotaxis, outer membrane channel function, degradation of aromatic ring compounds, and the breakdown of plant-derived carbon sources, in addition to many extracytoplasmic function sigma factors, providing the organism with the ability to respond to a wide range of environmental fluctuations. (wikipedia.org)
  • SBDS protein was also shown to localize to the pseudopod of Dictyostelium amoebae during chemotaxis.11 The interaction Rabbit Polyclonal to CARD11 of SBDS and a structural or regulatory cytoskeletal component is more than likely responsible for the observed defect in polymorphonuclear leukocyte chemotaxis. (cancercurehere.com)
  • We used the latter to illustrate phylogenetic Retigabine tyrosianse inhibitor conservation of gene proximity. (cancercurehere.com)
  • Outcomes Conservation of gene proximity in SBDS gene loci Phylogenetic evaluation of archeal loci (Figure 1) displays conservation of Retigabine tyrosianse inhibitor gene proximity. (cancercurehere.com)
  • PAIs are flanked by highly conserved tRNA genes that act as both integration and excision sites. (springeropen.com)
  • Additionally, tRNA loci are often found on extrachromosomal elements, such as plasmids and bacteriophages. (springeropen.com)
  • This indicates that the most likely mechanism for extrachromosomal element insertion is homologous recombination between the extrachromosomal element tRNA and PAI flanking tRNA loci (Hacker and Kaper 2000 ). (springeropen.com)
  • For axenic growth under laboratory conditions, it specifically relies on the external supply of N -acetylmuramic acid (MurNAc), which is an essential constituent of the peptidoglycan (PGN) of bacterial cell walls. (karger.com)
  • HN - 2008 BX - Lateral Sinus MH - Atrial Septum UI - D054087 MN - A07.541.459.249 MS - The thin membrane-like muscular structure separating the right and the left upper chambers (HEART ATRIA) of a heart. (bvsalud.org)
  • Besides recombinations with traces limited to the ospC gene itself, there was evidence of lateral gene transfers that involved (i) part of the ospC gene and one of the two flanks or (ii) the entire ospC gene and different lengths of both flanks. (cdc.gov)
  • This system is also portable to other carbon sources including D-glucose and glycerol as demonstrated by the repressible expression of the Escherichia coli lacZ encoded ß-galactosidase in T. reesei.We describe a novel, versatile set of promoters for T. reesei that can be used to drive recombinant gene expression in wheat straw cultures at different expression strengths and in an L-methionine repressible manner. (omicsdi.org)
  • C. jejuni does not possess classical virulence factors observed in bacterial enteropathogens such as enterotoxigenic Escherichia coli and Salmonella spp. (assignster.com)
  • Based on the Escherichia coli OmpA model, an eight-stranded amphipathic beta-barrel model for the membrane assembly of the N-terminal half of OmpAI and OmpAII was predicted. (shengsci.com)
  • An electron microscopy study has been made of the effects of dissolution of the plasma membrane of Escherichia coli with sodium dodecyl sulfate (SDS) on the organization of the nucleoplasm and the cytoplasm. (shengsci.com)
  • Expression of a Saccharomyces cerevisiae photolyase gene in Escherichia coli. (shengsci.com)
  • Various bacterial pathogens release NADase enzymes into the host cell that deplete the host's NAD + pool, thereby causing rapid cell death. (nature.com)
  • Pseudomonas aeruginosa is one of the most relevant human opportunistic bacterial pathogens. (biomedcentral.com)
  • The expression of genes encoding formate uptake transporter (PG0209) and formate tetrahydrofolate ligase ( fhs ) was drastically elevated, which indicates that formate metabolism plays a major role under aerobic conditions. (microbiologyresearch.org)
  • In addition, metal transport was affected, and while iron-uptake genes such as the genes encoding the haemin uptake locus ( hmu ) were downregulated, expression of manganese transporter genes, such as feoB2 , was elevated in the presence of oxygen. (microbiologyresearch.org)
  • In Finland Yersinia is one of the main causes of bacterial diarrhea in addition of Salmonella and Campylobacter. (9pdf.co)
  • Gene reduction analysis revealed that the gene deletion processes are under selective pressure, and many of the inactivations are probably related to the organism's interaction with its host environment. (asm.org)
  • This analysis retrieved 50 differentially regulated genes of which 33 were downregulated. (omicsdi.org)
  • [10] [11] A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated . (wikipedia.org)
  • Intragenic recombination among ospC genes is known, but the extent to which recombination extended beyond the ospC locus itself is undefined. (cdc.gov)
  • Insertional transposon mutagenesis is a frequently used technique with the enormous advantage not only of the generation of new phenotypes, but the identification of the mutated gene directly. (proteasomesignaling.com)
  • Also, genes encoding gingipain protease secretion/maturation regulator ( porR ) and protease transporter ( porT ) had reduced expression in the presence of oxygen, which also correlated with reduced protease activities under aerobic conditions. (microbiologyresearch.org)
  • We demonstrate that upon hitting a host cell, motile Pseudomonas aeruginosa induce a specific gene expression program. (elifesciences.org)
  • Microarray analysis revealed alteration in gene expression in the presence of 6 % oxygen. (microbiologyresearch.org)
  • The concomitant reduction of expression of a gene encoding the lactate transporter PG1340 suggests decreased utilization of this nutrient. (microbiologyresearch.org)
  • The results showed that baicalin-aluminum inhibited bacterial hemolytic activity, diminished biofilm formation, attenuated cytotoxicity to Caco-2 cells, downregulated the expression of genes encoding for clostridial toxins and extracellular enzymes such as alpha toxin (CPA), perfringolysin O (PFO), collagenase (ColA), and sialidases (NanI, NanJ). (bvsalud.org)
  • Additionally, baicalin-aluminum was found to negatively regulate the expression of genes involved in quorum sensing (QS) communication, including genes of Agr QS system (agrB, agrD) and genes of VirS/R two-component regulatory system (virS, virR). (bvsalud.org)
  • Tightly regulated gene expression systems are powerful tools to study essential genes and characterize potential drug targets. (omicsdi.org)
  • One of the limits of this system was its instability, leading to the selection of mutants in which the expression of the target gene was no longer repressible. (omicsdi.org)
  • This repressible promoter system could also be exploited to regulate gene expression during M. tuberculosis intracellular growth. (omicsdi.org)
  • L-Methionine repressible promoters for tuneable gene expression in Trichoderma reesei. (omicsdi.org)
  • Representative σ 66 -dependent gene transcription was repressed in the absence of rsbV1 or upon increased expression of RsbW, and increased upon elevated expression of RsbV1. (plos.org)
  • The primary data for 1-step growth, 2-step growth and gene expression summarized in Figs 4 and 5 are available in the S1 Dataset in the supplementary information. (plos.org)
  • However, little is known about the dynamic of infection in vivo, and information is lacking on both the intrinsic host response (gene expression) and its associated microbiota. (biomedcentral.com)
  • Expression of ompAI and ompAII separately in E. coli indicated that both genes could be independently transcribed from their own promoters and that both gene products were assembled into the E. coli outer membrane. (shengsci.com)
  • They have devised complex regulatory mechanisms responding to Fe 2+ unavailability that induce the expression of a series of genes to produce small iron chelators, termed siderophores [ 5 , 6 , 7 ], secrete them, and take up their iron-bound forms. (biomedcentral.com)
  • Antibiotic resistance typically induces a fitness cost that shapes the fate of antibiotic-resistant bacterial populations. (elifesciences.org)
  • We found that the distributions and frequencies of types of OspC genes differed between populations of B. burgdorferi in the Northeast, the Midwest, and California. (cdc.gov)
  • This review outlines aspects of the biosynthetzic pathway and genetic loci involved in xanthan biosynthesis, including the synthesis of the sugar nucleotide precursors, building of the repeat unit, as well as polymerization and export of the polymer. (caister.com)
  • The vast majority of these co-happening genes are linked to RNA modification and degradation, ie, probable exosome complicated exonuclease 2 (EC 3.1.13. (cancercurehere.com)
  • Upon entry into the periplasm, the incoming DNA is tight-ly bound and compacted by ComEA ( so tightly that ComEA overexpressed in the cytoplasm of E. coli kills the cell by sequestering the nucleoid ), and then shuttled to the ComEC inner membrane-pore complex. (asmblog.org)
  • Complementation of the E. coli phr-1 mutation was observed, strongly suggesting that the yeast PHR1 gene encodes a. (shengsci.com)
  • bored to see yet another post on horizontal gene transfer (HGT). (asmblog.org)
  • Unlike overall download the heritage of time that is site of well transient tailor components transient to the computationally full models, study process cell vectors regulatory plants that have far appealing predictions and cells of translation. (scoutconnection.com)
  • Chlamydia trachomatis is the leading cause of both bacterial sexually transmitted infection and infection-derived blindness world-wide. (plos.org)
  • While several regulated bacterial promoters have been characterized, few of them have been successfully used in mycobacteria. (omicsdi.org)