AnatomyChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
SOXD Transcription FactorsTranscription FactorsNerve TissueTranscription, GeneticPromoter Regions, GeneticDNA-Binding ProteinsSp1 Transcription FactorGene Expression RegulationMolecular Sequence DataBase SequenceTranscriptional ActivationBinding SitesTrans-ActivatorsBasic Helix-Loop-Helix Transcription FactorsRNA, MessengerProtein BindingNuclear ProteinsTranscription Factor AP-1Repressor ProteinsCell LineForkhead Transcription FactorsHomeodomain ProteinsGene Expression Regulation, DevelopmentalSignal TransductionAmino Acid SequenceDNABasic-Leucine Zipper Transcription FactorsTranscription Factor AP-2MutationCell NucleusCell DifferentiationTransfectionKruppel-Like Transcription FactorsTranscription Factors, TFIIChromatin ImmunoprecipitationGenes, ReporterYY1 Transcription FactorHeLa CellsSTAT3 Transcription FactorGATA4 Transcription FactorTranscription Factor TFIIDCells, CulturedActivating Transcription Factor 3NFATC Transcription FactorsSp3 Transcription FactorTranscription Initiation SiteNF-kappa BReverse Transcriptase Polymerase Chain ReactionZinc FingersPaired Box Transcription FactorsElectrophoretic Mobility Shift AssayActivating Transcription Factor 2Transcription Factor TFIIBEnhancer Elements, GeneticRegulatory Sequences, Nucleic AcidE2F1 Transcription FactorRNA Polymerase IIGene Expression ProfilingCloning, MolecularBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsMEF2 Transcription FactorsRecombinant Fusion ProteinsPlasmidsGATA3 Transcription FactorGATA1 Transcription FactorGATA2 Transcription FactorGene ExpressionGene Expression Regulation, FungalTCF Transcription FactorsGATA Transcription FactorsMicrophthalmia-Associated Transcription FactorLuciferasesSTAT1 Transcription FactorProtein Structure, TertiaryActivating Transcription Factors
Family of Transcription FactorsProteinsElucidateRolesFoundSpecificDevelopmentFamily of transcription factorsBiologicalGenesHigh-mobility-DataSequenceHumanCells
Family of Transcription Factors1
  • It is encoded by a gene on the Y chromosome and contains a specific HMG-BOX DOMAIN that is found within members of the SOX family of transcription factors. (nih.gov)
Proteins2
  • We focus our attention on three families of transcription factors that are known to have roles in vertebrate chondrogenesis: Sox and the Ant- and Prd- class families of the homeodomain proteins. (europa.eu)
  • We used histochemistry to map differentially expressed proteins in mouse and human gut tissues at different stages of development, in different regions. (figshare.com)
Elucidate1
  • Transcription factor binding motifs help to elucidate regulatory mechanism. (systemsbiology.net)
Roles1
Found1
  • A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. (bvsalud.org)
Specific1
  • Transcription factors were grouped according to their specific expression in enteric progenitor cells (such as MEF2C), enteric neurons (such as SOX4), or neuron subpopulations (such as SATB1 and SOX6). (figshare.com)
Development2
  • RESULTS: We identified 147 transcription and signaling factors that varied in spatial and temporal expression during development of the mouse ENS. (figshare.com)
  • A transcription factor that plays an essential role in the development of the TESTES . (nih.gov)
Family of transcription factors1
  • Sox6 belongs to the Sry (sex-determining region Y)-related high-mobility-group-box family of transcription factors, which control cell-fate specification of many cell types. (unimib.it)
Biological1
  • This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). (nih.gov)
Genes1
  • Because the sequences of these sites are of low information content, we pursue multiple approaches, including better characterizing transcriptional start sites and alternative proximal promoters, detecting clusters of transcription factor binding sites using probabilistic models, and identifying genes that are co-regulated and taking advantage of the enrichment of the sequence motifs in their promoters. (umassmed.edu)
High-mobility-1
  • SOX5 is a transcription factor with homology to the high mobility group box region of the testis-determining factor, SRY. (elsevierpure.com)
Data1
  • We take an integrative approach using extensive high-throughput genomic and epigenomic data, such as chromatin-immunoprecipitation of transcription factors, nucleosome positioning, histone modifications, DNA methylation, and DNA replication. (umassmed.edu)
Sequence2
  • Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors. (umassmed.edu)
  • A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN . (nih.gov)
Human2
  • Functional analysis of transcription factor binding sites in human promoters. (umassmed.edu)
  • Like FOXJ1, a transcription factor known to be essential for motile ciliogenesis, S-SOX5 stimulated mouse and human SPAG6 promoter function in BEAS-2B cells, but the effect was abrogated when the SOX5 binding sites were mutated or deleted. (elsevierpure.com)
Cells1
  • We also demonstrate that FGF signalling influences the BMP signalling pathway activity in the region around cumulus cells. (bvsalud.org)