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HydrogelGelatinBiocompatible MaterialsHydrogelsTissue EngineeringTissue ScaffoldsMaterials TestingGelatin Sponge, AbsorbableSilkBiomimetic MaterialsPolyethylene GlycolsBone SubstitutesPolymersSurface PropertiesForeign-Body ReactionImplants, ExperimentalBiomimeticsProstheses and ImplantsCeramicsChitosanCoated Materials, BiocompatiblePolyestersNanofibersSiliconesPorosityBone RegenerationHexuronic AcidsGlucuronic AcidMicroscopy, Electron, ScanningFibroinsContact Lenses, HydrophilicAlginatesMicrospheresDrug Delivery SystemsNanostructuresPolyglycolic AcidRheologyPolyhydroxyethyl MethacrylateGuided Tissue RegenerationElastic ModulusPolyvinyl AlcoholAbsorbable ImplantsCell Culture TechniquesExtracellular MatrixDurapatiteRegenerative MedicinePolystyrenesBiomedical EngineeringMechanical PhenomenaHyaluronic AcidDelayed-Action PreparationsTitaniumDrug CarriersMesenchymal Stromal CellsGiant Cells, Foreign-BodyCalcium PhosphatesSilicone ElastomersAdsorptionCell AdhesionCapsulesNanoparticlesAcrylatesBandages, HydrocolloidParticle SizeGlassTensile StrengthCollagenPhotoelectron SpectroscopyMethacrylatesCells, CulturedNanotechnologyBioengineeringViscosityContact Lenses, Extended-WearElastomersGelsViscoelastic SubstancesOsteogenesisCell SurvivalInjectionsAcrylic ResinsMatrix Metalloproteinase 2Polymethyl MethacrylateWettabilitySpectroscopy, Fourier Transform InfraredPolyurethanesCell ShapeStaphylococcus epidermidisPoloxamerAcrylamidesCross-Linking ReagentsCells, ImmobilizedCryogelsSericinsGelatinasesContact LensesCell ProliferationAwards and PrizesDecanoatesPolyvinyl Chloride
GelMAMethacryloylScaffoldsRegenerationBiofabricationNanoparticlesMedicineScaffoldTissuesMethacrylateCollagenAlginate hydrogelNanocomposite hydrogelsExtracellular MatrixBiocompatibilityBioengineeringNeuralPolymersTranslational researchTunable2018WoundHyaluronicVascularMechanicallyMechanical properties2019ConstructsMesenchymalTherapyGelationBiomimeticBone tissueBioactiveCell2017BehaviorBiodegradabilityWeakFabricateGrowth FactorsFibersStrategiesResearchSupportiveCells
GelMA23
  • For example, he has developed and popularized gelatin methacryloyl (GelMA) which has become one of the main materials for 3D bioprinting industry. (wikipedia.org)
  • He also developed electrically conductive, tunable hydrogels by mixing GelMA with nanomaterials, including gold nanoparticles and carbon-based nanomaterials. (wikipedia.org)
  • The first Good Manufacturing Practice (GMP)-ready range of gelatin methacryloyl (GelMA) biomaterials suitable for preclinical and clinical applications. (pharmiweb.com)
  • X-Pure ® GelMA is part of the X-Pure ® portfolio of ultra-pure gelatins and collagens, suitable for use as biomaterials in 3D bioprinting, tissue engineering, and regenerative medicine. (pharmiweb.com)
  • In GelMA hydrogels, the most versatile biological environment for cells, the inherent bioactivity, biodegradability, and cell compatibility of gelatin are combined with the ability to tailor photo-crosslinking. (pharmiweb.com)
  • X-Pure ® GelMA - The first GMP-ready gelatin methacryloyl. (pharmiweb.com)
  • However, standard GelMA products often carry high and variable levels of soluble impurities originating from either the gelatin raw material or the chemical synthesis process. (pharmiweb.com)
  • X-Pure ® GelMA is our latest addition to our biomedical range of ultra-pure gelatins and collagens and our range will be further extended as we move forward with products bringing added value to the whole biomedical industry. (pharmiweb.com)
  • We, therefore, aimed to develop a 3D-printed dual rifampicin (Rif)- and vancomycin (Van)-loaded polylacticco-glycolic acid (PLGA) nanoparticles (NPs) delivery system based on hydrogels made of gelatin methacrylate (GelMA). (desktopmetal.com)
  • Herein, we develop a hybrid neuro-instructive hydrogel that combines the properties of a photo-crosslinkable gelatin methacrylate (GelMA) and self-assembling peptide amphiphiles (PAs) bearing a laminin-derived neuro-inductive epitope (PA-GSR). (metu.edu.tr)
  • Spectroscopic, microscopic and theoretical techniques show that the cationic PA-GSR(+) electrostatically co-assembles with the negatively charged GelMA to create weak hydrogels with hierarchically ordered microstructures, which were further photo-crosslinked to create mechanically robust hydrogels. (metu.edu.tr)
  • Dynamic oscillatory rheology and micromechanical testing show that photo-crosslinking of the co-assembled GelMA and PA-GSR(+) hydrogel results in robust hydrogels displaying improved stiffness. (metu.edu.tr)
  • Gene expression analysis was used to show that GelMA/PA-GSR(+) hydrogels can induce human mesenchymal stem cells (hMSCs) into neural-lineage cells and supports neural-lineage specification of neuroblast-like cells (SH-SY5Y) in a growth-factor-free manner. (metu.edu.tr)
  • It had been discovered that the addition of gelatin methacrylate (GelMA) into HA methacrylate (HAMA) marketed KC7F2 cell dispersing in the cross types KC7F2 hydogels. (ecologicalsgardens.com)
  • The HAMA-GelMA hydrogels exhibited extraordinary tunability behavior and could be ideal for cardiovascular tissues anatomist applications. (ecologicalsgardens.com)
  • Methacrylated gelatin (GelMA) is normally biaoactive and it interacts with several cell lines.37 Furthermore GelMA allows the growing of encapsulated cells because of its cell adhesive functional groups.37 much like collagen gels UV-crosslinked gelatin hydrogels are mechanically weak However. (ecologicalsgardens.com)
  • Within this study we've utilized different compositions of HAMA and GelMA to create Mouse monoclonal to FUK tunable cross types hydrogels and characterized their natural and mechanised properties. (ecologicalsgardens.com)
  • Furthermore biological replies of individual umbilical cable vein endothelial cells (HUVECs) to HAMA-GelMA hybrids had been seen as a seeding cells over the hydrogel areas or encapsulating them within 3D buildings KC7F2 of hybrids produced through the use of different compositions of HAMA and GelMA. (ecologicalsgardens.com)
  • 2.2 Synthesis of polymer precursors GelMA was synthesized based on a procedure defined previously.39 Briefly 10 grams of gelatin was coupled with 100 mL DPBS at 50° C and stirred until fully dissolved. (ecologicalsgardens.com)
  • Gelatin methacrylate (GelMA) is a photopolymerizable hydrogel synthesized from gelatin and has recently emerged as a potentially attractive material for tissue engineering applications. (biomedcentral.com)
  • GelMA+hypo-CM hydrogel was prepared, and a comprehensive evaluation of morphology, protein release efficiency, degradation rate, mechanical properties, and rheology properties were performed. (biomedcentral.com)
  • Additionally, FCS, HS, and hPL were used to formulate Gelatin-methacryloyl (GelMA) hydrogels in order to evaluate the influence of the different supplements on the cell spreading and proliferation of cells growing in 3D culture. (frontiersin.org)
  • In comparison to FCS and HS, the addition of hPL to GelMA hydrogels during the encapsulation of hAD-MSCs resulted in enhanced cell spreading and proliferation. (frontiersin.org)
Methacryloyl2
  • As a demonstration, we create a gelatin methacryloyl fiber hydrogel with soft tissue-like mechanical properties, such as low Young's modulus (0.1 to 0.3 MPa), high strength (1.1 ± 0.2 MPa), high toughness (9,100 ± 2,200 J/m 3 ), and high fatigue resistance (2,300 ± 500 J/m 2 ). (nih.gov)
  • The new range covers a broad choice of molecular weights and modification degrees of gelatin methacryloyl biomaterials, allowing close customer collaboration for custom-made solutions. (pharmiweb.com)
Scaffolds12
  • Odontogenic Differentiation of Human Dental Pulp Stem Cells on Hydrogel Scaffolds Derived from Decellularized Bone Extracellular Matrix and Collagen Type I PLOS ONE. (nottingham.ac.uk)
  • Extrusion-based three-dimensional (3D) printing of gelatin is important for additive manufactured tissue engineering scaffolds, but gelatin's thermal instability has remained an ongoing challenge. (desktopmetal.com)
  • Her research interests include the preparation and design of materials and scaffolds for in vitro and in vivo fundamental studies, and a further focus is the provision of useful tools to assess mechanisms that govern cell behavior in regenerative medicine. (ibecbarcelona.eu)
  • 13. Enzymatically functionalized RGD-gelatin scaffolds that recruit host mesenchymal stem cells in vivo and promote bone regeneration. (nih.gov)
  • Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds, Journal of biomedical supplies analysis. (porfectlife.com)
  • Electrospun oriented gelatin-hydroxyapatite fiber scaffolds for bone tissue engineering. (porfectlife.com)
  • Salifu AA, Lekakou C, Labeed F. Multilayer mobile stacks of gelatin-hydroxyapatite fiber scaffolds for bone tissue engineering. (porfectlife.com)
  • In vitro and in vivo research of BMP-2-loaded PCL-gelatin-BCP electrospun scaffolds. (porfectlife.com)
  • Poly(ɛ-caprolactone)/gelatin composite electrospun scaffolds with porous crater-like buildings for tissue engineering. (porfectlife.com)
  • In the present work, a simple process was developed to fabricate hybrid hydrogel scaffolds with a biomimetic architecture from the natural urinary bladder. (sharif.edu)
  • Thereafter, we discuss the recent approaches combining 2D nanomaterials and three-dimensional (3D) printing to produce hydrogel-based scaffolds for exquisite neural tissue engineering. (accscience.com)
  • Through this review, we aim to contribute to crafting a range of strategies for the biomedical applications of 3D printing with diverse nanomaterials and hope to encourage further research on understanding the mechanisms of toxicity as well as the synergistic effects of 2D nanomaterials and hydrogel scaffolds for neural tissue engineering and regeneration. (accscience.com)
Regeneration11
  • It means that the successful cardiac regenerative strategy requires re-vascularization mechanisms to validate long-term myocardial regeneration. (biomedcentral.com)
  • This work highlights a new approach for the design of PA-based hybrid hydrogels with robust mechanical properties and biological functionalities for nerve tissue regeneration. (metu.edu.tr)
  • In 2007, she moved to the department of Orthopaedics, University Medical Center in Utrecht, to work on bone and cartilage tissue regeneration within the Hospital's strategic impulse on regenerative medicine. (umcutrecht.nl)
  • She was awarded with a postdoc fellow from the Ministry of Science at the Technical University of Catalonia in Biomaterials for bone tissue regeneration and since 2010 has been professor at this university. (ibecbarcelona.eu)
  • ROKIT Healthcare is a global healthcare company committed to providing the safest and most effective autologous organ regeneration platform using its proprietary biofabrication technologies across all types of applicable diseases in the field of regenerative medicine. (biofabricationsociety.org)
  • Through a convergence of know-how's and innovation in the areas of R&D (i.e. 3D bioprinting, autologous stem cell technologies, and human-derived biomaterials), surgical medicine, and regulatory affairs, ROKIT Healthcare believes in supplying customized organ regeneration platform services that will drastically change the way we trust and manage the health of our own body. (biofabricationsociety.org)
  • In addition, our results indicate that implantation of functionalized nerve protectors repopulated with GiSCs significantly accelerated functional recovery and axonal regeneration of crush-injured rat sciatic nerves accompanied by increased infiltration of pro-regenerative (M2) macrophages while a decreased infiltration of pro-inflammatory (M1) macrophages. (biomedcentral.com)
  • From replacement to regeneration, the nascent field of biomaterials is attracting mounting interest, with current studies focusing mostly on biocompatibility, biotoxicity, biodegradability and lifespan of the implant in the body - issues not considered a thousand years ago. (omicsonline.org)
  • Her research is focused on developing biomaterials and harnessing their potential for tissue regeneration. (southampton.ac.uk)
  • She joined the Bone and Joint Research Group at the Centre for Human Development, Stem cells, and Regenerative Medicine in 2016 and focused on developing clay nanoparticles for stem cell-driven tissue regeneration funded by Dr Dawson's EPSRC fellowship ( Nanoclay group ). (southampton.ac.uk)
  • She is currently focused on modulating macrophage and stem cell responses to bioactive Nanoclay for bone regeneration in collaboration with Kyoto University, Japan, funded by MRC-AMED Regenerative Medicine and Stem Cell Research Initiative grant. (southampton.ac.uk)
Biofabrication3
  • By the number of citations, he is the most cited author of in various journals in the field of biomaterials like Biomaterials, Advanced Healthcare Materials, Biofabrication, Tissue Engineering - Part B: Reviews. (wikipedia.org)
  • Our research program focuses on the design and implementation of extracellular matrix-inspired hydrogel biomaterials for the biofabrication of tissue and tumor organoids, organ-on-a-chip systems, and cancer-on-a-chip systems for drug screening, disease modeling, and personalized medicine. (osu.edu)
  • She has worked on designs and chemical modification of scaffold/hydrogel and assessment of them by in vitro and in vivo studies, and published in journals such as Nature Communications, Biomaterials, Biofabrication, and Advanced Healthcare Materials. (southampton.ac.uk)
Nanoparticles4
  • He combined silica nanoparticles with gelatin to engineer shear-thinning materials for the embolization of blood vessels in the peripheral vasculature. (wikipedia.org)
  • Moreover, her research work has included the design and characterization of an injectable hydrogel for the administration of nanoparticles in vivo , under Prof. Valeria Chiono and postdoc Elena Marcello's supervision. (polito.it)
  • Chen H, Zhang J, Wu H, Li Y, Li X, Zhang J, Huang L, Deng S, Tan S, Cai X. Fabrication of a Cu Nanoparticles/Poly(ε-caprolactone)/gelatin fiber membrane with good antibacterial exercise and mechanical property through inexperienced electrospinning. (porfectlife.com)
  • The addition of ZrO2 nanoparticles (NPs) into the alginate-gelatin hydrogel is considered to improve mechanical and chemical properties. (sharif.edu)
Medicine29
Scaffold3
  • Degradation of tissues engineered constructs is vital for most applications in regenerative medication to permit for the deposition of recently formed ECM with the cells.36 Cellular behavior (e.g. dispersing migration differentiation) is normally strongly inspired by degradation properties from the scaffold since scaffold degradation allows deposition and development of new tissues. (ecologicalsgardens.com)
  • This method entails a 3D bioprinting technique based on a gelatin/alginate hydrogel to construct a multilayer composite scaffold. (hairlosscure2020.com)
  • 2019). Geometric anisotropy on biomaterials surface for vascular scaffold design: engineering and biological advances. (wku.edu.cn)
Tissues10
  • Here, we present a thermomechanical approach to replicate the combinational properties of soft tissues in protein-based photocrosslinkable hydrogels. (nih.gov)
  • Extracellular matrix hydrogels from decellularized tissues: Structure and function. (nottingham.ac.uk)
  • Another technology to generate 3D engineered cardiac tissues using cardiac cells and biomaterials also validated successful induction of vascular network originated from both host and graft-derived vascular cells. (biomedcentral.com)
  • The incorporation of exogenous lactate into cardiac tissues is a regenerative strategy that is rapidly gaining attention. (ibecbarcelona.eu)
  • Because of their abundance within the indigenous ECM HA and collagen/gelatin hybrids possess great potential to be utilized for different tissues anatomist applications (e.g. neural bone tissue vascular cardiac epidermis) and regenerative medication research. (ecologicalsgardens.com)
  • The researchers have become so adept at it that they now can print biomaterials that mimic the structural, mechanical, and biological properties of real human tissues. (nih.gov)
  • Bioinks are materials used to create engineered and artificial biological tissues using a 3D bioprinter, and are made up of a combination of cells, hydrogels, and polypeptides. (innoregen.com)
  • Ultrasound (high-frequency pressure waves) can be used to remotely interact with cells, biomaterials, and tissues. (thearmstronggroup.co.uk)
  • A major focus of our research is the development of new ultrasound-based technologies for driving the assembly of biomaterials and engineered tissues. (thearmstronggroup.co.uk)
  • Marine biomaterials offer a range of advantages for drug delivery, including the ability to control the release of drugs over a specific period, to target specific cells or tissues, and to improve drug efficacy. (nanoschool.in)
Methacrylate1
  • 2 Materials AND Strategies 2.1 Components Methacrylic anhydride Gelatin (type A from porcine epidermis) and 3-(trimethoxysilyl) propyl methacrylate (TMSPMA) had been extracted from Sigma-Aldrich (St Louis MO). (ecologicalsgardens.com)
Collagen9
  • It also introduced the world's first native human collagen and gelatin bioinks for tissue and organ bioprinting. (azbio.org)
  • The hydrogels mimic the human body's extracellular matrix, which contains substances including proteins, collagen and hyaluronic acid. (go.ke)
  • The FRESH system uses a bioink that consists of collagen (or other soft biomaterials) embedded in a thick slurry of gelatin microparticles and water. (nih.gov)
  • GMSCs encapsulated in the methacrylated 3D-collagen hydrogel were co-cultured with THP-1-derived macrophages, and the secretion of anti-inflammatory cytokine IL-10 or inflammatory cytokines TNF-α and IL-1β in the supernatant was determined by ELISA. (biomedcentral.com)
  • GMSCs encapsulated in the methacrylated 3D-collagen hydrogel were directly converted into Schwann-like cells (GiSCs) characterized by the expression of S-100β, p75NTR, BDNF, and GDNF. (biomedcentral.com)
  • In vitro, co-culture of GMSCs encapsulated in the 3D-collagen hydrogel with macrophages remarkably increased the secretion of IL-10, an anti-inflammatory cytokine characteristic of pro-regenerative (M2) macrophages, but robustly reduced LPS-stimulated secretion of TNF-1α and IL-1β, two cytokines characteristic of pro-inflammatory (M1) macrophages. (biomedcentral.com)
  • We are the first company in Korea to work on developing bioinks that combine human-derived collagen/human-derived extracellular matrices with hydrogels. (innoregen.com)
  • What is the gel strength of collagen hydrogels? (advancedbiomatrix.com)
  • My collagen is not forming a hydrogel. (advancedbiomatrix.com)
Alginate hydrogel1
  • Alginate-hydrogel versus alginate-solid system. (ull.es)
Nanocomposite hydrogels2
  • Therefore, nanocomposite hydrogels have been manufactured by the freeze-drying procedure utilizing oxidized alginate-gelatin with ZrO2 NPs as a reinforcement. (sharif.edu)
  • The fabricated nanocomposite hydrogels were character-ized by FTIR, FESEM, and rheometer. (sharif.edu)
Extracellular Matrix3
Biocompatibility2
  • Polymers offer a wide range of versatility, in particular regarding shape and mechanical characteristics, and their biocompatibility is unmatched by other biomaterials, such as metals and ceramics. (biomedcentral.com)
  • This issue will bring together basic science, novel materials, imaging, quantititative methodologies as well as the examining the importance of biocompatibility in translating new biomaterials into the clinic. (mdpi.com)
Bioengineering1
Neural1
Polymers2
  • Although hydrogels prepared from synthetic polymers can be strong and tough, they do not have the desired bioactivity for emerging biomedical applications. (nih.gov)
  • Gelatin and alginate are biocompatible and biodegradable polymers. (sharif.edu)
Translational research2
  • The supply of high-quality and affordable human-derived biomaterials for translational research is severely limited. (azbio.org)
  • In order to both mitigate the expense and improve the long-term effectiveness of orthopaedic surgery, including arthroplasty, the conception and creation of new biomaterials for treatment of defective joints and bones in the human body has become an emerging area of translational research over the last decade. (omicsonline.org)
Tunable1
  • Electrostatic interaction and ultraviolet light crosslinking mechanisms were combined to create dual-crosslinked hybrid hydrogels with tunable stiffness. (metu.edu.tr)
20181
  • 2018). Reliable laser fabrication: the quest for responsive biomaterials surface, Journal of Materials Chemistry B, 6, 3612-3631. (wku.edu.cn)
Wound5
  • Here, we developed a versatile hydrogel wound dressing, comprising a straightforward physical mixture of royal jelly-derived extracellular vesicles (RJ-EVs) and methacrylic anhydride modified sericin (SerMA), to accelerate wound healing by inhibiting inflammation and promoting vascular reparation. (thno.org)
  • Meanwhile, the photocrosslinked SerMA hydrogel with its porous interior structure and high fluidity made it a good candidate for wound dressing. (thno.org)
  • The RJ-EVs can be gradually released from the SerMA hydrogel at the wound site, ensuring the restorative effect of RJ-EVs. (thno.org)
  • In a full-thickness skin defect model, the SerMA/RJ-EVs hydrogel dressing accelerated wound healing with a healing rate of 96.8% by improving cell proliferation and angiogenesis. (thno.org)
  • This SerMA/RJ-EVs hydrogel dressing offers a simple, safe and robust strategy for modulating inflammation and vascular impairment for accelerated wound healing. (thno.org)
Hyaluronic1
  • Our biomaterial systems are largely hyaluronic acid-based with additional custom ECM component addons, synthetically modified in the lab. (osu.edu)
Vascular1
  • The application of gelatin hydrogel microsphere between the cell sheet stacks enabled us to generate thick stacked cell sheets with functional vascular network in vivo. (biomedcentral.com)
Mechanically1
  • However, to the best of our knowledge, few studies have used AI to predict how hydrogels evolve with time (kinetics) and behave mechanically based on their multifactorial composition. (rheolution.com)
Mechanical properties2
20191
  • Humabiologics launched the first of its kind human bone gelatin in late 2019 and provides one of the most affordable native human skin collagens for hydrogel applications and 3D bioprinting. (azbio.org)
Constructs2
  • In addition, the hydrogel constructs were cultivated in media supplemented with three different supplements. (frontiersin.org)
  • This effect was promoted even further by cultivating the hydrogel constructs in hPL-supplemented media. (frontiersin.org)
Mesenchymal2
  • 4. Oxidized alginate hydrogels with the GHK peptide enhance cord blood mesenchymal stem cell osteogenesis: A paradigm for metabolomics-based evaluation of biomaterial design. (nih.gov)
  • 9. Human umbilical cord blood mesenchymal stem cells expansion via human fibroblast-derived matrix and their potentials toward regenerative application. (nih.gov)
Therapy2
  • Stem cell-based cardiac regenerative therapy is expected to be a promising strategy for the treatment of severe heart diseases. (biomedcentral.com)
  • Collectively, these findings suggest that Schwann-like cells converted from GMSCs represent a promising source of supportive cells for regenerative therapy of PNI through their dual functions, neurotrophic effects, and immunomodulation of pro-inflammatory (M1)/pro-regenerative (M2) macrophages. (biomedcentral.com)
Gelation1
  • An AI model for the prediction of the gelation kinetics and viscoelastic properties of PEGDA hydrogels was developed. (rheolution.com)
Biomimetic1
  • Fabrication of cross types hydrogels is a popular method of improve materials and/or natural properties of biomaterials.1 Although HA-gelatin cross types hydrogels are appealing biomimetic substrates38 their materials properties haven't been thoroughly characterized. (ecologicalsgardens.com)
Bone tissue2
  • Osypko KF, Ciszyński MP, Kubasiewicz-Ross P, Hadzik J. Bone tissue 3D bioprinting in regenerative dentistry through the perspective of the diamond concept of healing: A narrative review. (edu.pl)
  • Grandfield Niobium pentoxide and hydroxyapatite particle loaded electrospun polycaprolactone/gelatin membranes for bone tissue engineering colloids and surfaces. (porfectlife.com)
Bioactive1
  • This paper reviews the main developments in the field of bioactive glass and its variants, covering the importance of control of hierarchical structure, synthesis, processing and cellular response in the quest for new regenerative synthetic bone grafts. (materialstoday.com)
Cell5
  • The fiber architecture also regulates cellular mechanoresponse and supports cell remodeling inside hydrogels. (nih.gov)
  • To overcome this problem, we developed a cell-sheet stacking method to insert gelatin hydrogel microsphere (GHM), which is a biomaterial to work as a spacer between the cell sheets securing oxygen and nutrition supply among the whole cell sheet stacks. (biomedcentral.com)
  • In biomaterials, some interesting applications have been explored, such as the screening of peptide interaction for the intelligent design of self-assembly hydrogels [3] or to predict cell adhesion and protein adsorption on polymeric surfaces based on their surface topology [4]. (rheolution.com)
  • In April 2016, the company entered the biomedical industry with the launch of INVIVO, a cell and biomaterial 3D printer equipped with clean chamber technology. (biofabricationsociety.org)
  • She has more than nine years of post-doctoral experience in the field of tissue engineering and cell/tissue-biomaterial interactions. (informaticsstudies.org)
20171
  • 2017, Peripheral nerve injury: Current challenges, conventional treatment approaches, and new trends in biomaterials-based regenerative strategies. (accscience.com)
Behavior1
  • However, scientists struggle to understand how multiple parameters influence each other and how this relates to the behavior and the performance of hydrogels [2]. (rheolution.com)
Biodegradability1
  • One of the key advantages of marine-based biomaterials is their biodegradability, which allows them to break down over time, reducing the risk of adverse reactions or toxicity. (nanoschool.in)
Weak1
Fabricate1
  • Soy protein resins have been used to fabricate green composites for many applications such as hydrogels, adhesives, plastics, films, coatings and emulsifiers, and it has also been reported as a promising material for biotechnological and biomedical utilization. (rroij.com)
Growth Factors1
  • This glue is Atala's nickname for bioink, a printable mixture of living cells, water-rich molecules called hydrogels, and the media and growth factors that help the cells continue to proliferate and differentiate, Lewis said. (go.ke)
Fibers2
  • Both platforms contained electrospun poly(lactic acid) (PLA) fibers and an alginate (Alg) hydrogel. (ibecbarcelona.eu)
  • In the first platform, named L/K(x)/Alg-PLA, lactate and proteinase K (x mg of enzyme per 1 g of PLA) were directly loaded into the Alg hydrogel, into which PLA fibers were assembled. (ibecbarcelona.eu)
Strategies3
  • However, the extent of the engraftment was not fully satisfactory requiring additional strategies to enhance the regenerative capacity. (biomedcentral.com)
  • She is inspired by the natural mechanisms of the body for bone development and repair that she aims to adopt in her regenerative strategies. (umcutrecht.nl)
  • Translation of the regenerative strategies to clinical practice is driving current research. (umcutrecht.nl)
Research2
  • Humabiologics has solved this problem through their transformative technology that converts donated tissue that is not used for transplant into affordable and high-quality biomaterials for research. (azbio.org)
  • Overall, research into the potential of marine biomaterials for drug delivery is ongoing, and the results so far are promising. (nanoschool.in)
Supportive1
  • The same technological ingenuity is also now being applied with bioinks-printable gels containing supportive biomaterials and/or cells-to print out tissue, bone, blood vessels, and, even perhaps one day, viable organs. (nih.gov)
Cells2
  • Also, metabolomics analysis suggests that the hydrogel alters the metabolite profiles in the cells by affecting multiple molecular pathways. (metu.edu.tr)
  • Recently, she showed the potential of allogeneic cells in this regenerative approach and currently studies the impact of the interaction with the immune system, devitalization and avenues for scale-up and clinical translation (see also here ). (umcutrecht.nl)