Diacetyl reductase ((S)-acetoin forming) (EC 1.1.1.304, (S)-acetoin dehydrogenase) is an enzyme with systematic name (S)-acetoin:NAD+ oxidoreductase. (wikipedia.org)
While the butanediol dehydrogenase activity is reversible, diacetyl reductase activity is irreversible. (wikipedia.org)
Searching for up to 100 curated homologs for 201943 SO2813 oxidoreductase, short chain dehydrogenase/reductase family (NCBI ptt file) (254 a.a. (lbl.gov)
This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). (thermofisher.com)
Diacetyl was metabolized in nasal tissues in vitro, likely by is metabolized by diacetyl reductase (also known as diacetyl reductase, an enzyme known to be inhibited by butyric dicarbonyl nicotine adenine dinucleotide phosphate reductase acid. (cdc.gov)
Butyric acid is explained by inhibition of diacetyl reductase. (cdc.gov)
Oxidoreductase1
Oxidoreductase (Mercury (II) reductase) [Ensembl]. (ntu.edu.sg)
Butanediol2
The enzyme was NAD(H)-specific and its optimal activity for acetoin reduction was observed at pH 6.5 and 55 °C. The optimal pH and temperature for 2,3-butanediol oxidation were pH 10 and 45 °C, respectively. (mdpi.com)
Concentrations of 2,3-butanediol and acetoin obtained for the individual constructs are given as one bar (solid area = 2,3-butanediol, dashed area = acetoin). (biomedcentral.com)
NADH2
This enzyme catalyses the following chemical reaction (S)-acetoin + NAD+ ⇌ {\displaystyle \rightleftharpoons } diacetyl + NADH + H+ The reaction is catalysed in the reverse direction. (wikipedia.org)
NADPH-dependent acetoacetyl-CoA reductase (phaB) is the enzyme which plays an essential role in P(3HB) synthesis by catalyzing the conversion of the intermediates. (bvsalud.org)
Results showed that the cell age of 4 h, induction time of 12 h at 37°C were identified as the optimal conditions for the enzyme reductase expression. (bvsalud.org)
The findings provide an alternative for the synthesis of the reductase enzyme which can be used in the industrial-scale production of the biodegradable polymers. (bvsalud.org)
Conclusion We have been able to develop a clinically safe and effective inhibitor of the enzyme 5-alpha reductase with the potential to effectively suppress androgen production in normal men. (woowha-surgery.com)
Putative1
Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. (lbl.gov)
Acid1
BFV are a complex mixture of volatile agents containing of diacetyl and butyric acid, two components of BFV, and to develop a hybrid computational fluid dynamic-physiologically diacetyl (2,3-butanedione), acetoin, 2-nonanone, acetic acid, based pharmacokinetic model (CFD-PBPK) to describe these and butyric acid, among other vapors (Boylstein et al. (cdc.gov)
Dicarbonyl5
Dicarbonyl/L- xylulose reductase (DCXR) metabolizes diacetyl to acetoin, which lacks this a-dicarbonyl group. (cdc.gov)
The purified recombinant proteins of the five species were about 100-kDa homotetramers with NADPH-linked reductase activity for alpha-dicarbonyl compounds, catalyzed the oxidoreduction between xylitol and l-xylulose, and were inhibited competitively by n-butyric acid. (nih.gov)
Therefore, the proteins are designated as dicarbonyl/l-xylulose reductases (DCXRs). (nih.gov)
Many of these chemicals are detoxified by carbonyl reductases in the lung, in particular, dicarbonyl/l-xylulose reductase (DCXR), a multifunctional enzyme important in glucose metabolism. (nih.gov)
Quinones inhibited reduction of this dicarbonyl, causing an accumulation of diacetyl in the cells and culture medium and a decrease in acetoin, the reduced product of diacetyl. (nih.gov)