Recurrent torsades de pointes. Medical search. Frequent questions

Torsade de pointes is an uncommon and distinctive form of polymorphic ventricular tachycardia (VT) characterized by a gradual change in the amplitude and twisting of the QRS complexes around the isoelectric line (see the image below). (medscape.com)
Torsades de pointes ventricular tachycardia is a specific form of polymorphic ventricular tachycardia in patients with a long QT interval. (msdmanuals.com)
Upon presentation to hospital, she was found to have recurrent non-sustained salvos of polymorphic ventricular tachycardia (VT) (Figure 2), with a prolonged QT interval (Figure 3). (acc.org)
Cardiac monitoring showed recurrent runs of polymorphic ventricular tachycardia demonstrating pause dependence that was typical of drug-induced prolongation of QT interval (see Figure 2 ). (radcliffecardiology.com)
She continued to have recurrent runs of polymorphic ventricular tachycardia in spite of correction of hypokalemia and administration of intravenous magnesium. (radcliffecardiology.com)
The most common form of polymorphic VT is Torsade de pointes . (wikidoc.org)
2. Intravenous beta blockers are useful for patients with recurrent polymorphic VT especially if ischemia is suspected or cannot be excluded. (wikidoc.org)
3. Intravenous loading with amiodarone is useful for patients with recurrent polymorphic VT in the absence of abnormal repolarization related to congenital or acquired LQTS . (wikidoc.org)
One specific type of polymorphic ventricular tachycardia is known as Torsades de Pointes , which most commonly occurs in the setting of the acquired (drug-induced) long QT syndrome. (njfaint.com)
Polymorphic ventricular tachycardia (non-Torsades) should be considered secondary to ischemia or metabolic disturbances until proven otherwise. (njfaint.com)

Torsade de pointes, often referred to as torsade, is associated with a prolonged QT interval, which may be congenital or acquired. (medscape.com)
Torsades de pointes with prolonged QT interval (12-lead ECG of torsades de pointes (TdP) in a 56-year-old white female with low blood potassium (2.4 mmol/L) and low blood magnesium (1.6 mg/dL). (medscape.com)
The association between torsade and a prolonged QT interval has long been known, but the mechanisms involved at the cellular and ionic levels have been made clearer in approximately the last decade. (medscape.com)

Common causes for torsades de pointes include drug-induced QT prolongation and less often diarrhea, low serum magnesium, and low serum potassium or congenital long QT syndrome. (wikipedia.org)
During post-marketing surveillance, there have been very rare cases of QT prolongation and torsade de pointes in patients taking fluconazole. (tajgenerics.com)

Long QT syndrome (LQTS) is a heritable channelopathy characterized by a prolonged cardiac repolarization that may trigger ventricular arrhythmias (torsade de pointes), recurrent syncopes, seizure, or sudden cardiac death (SCD) (Cerrone et al. (preventiongenetics.com)
VANFLYTA is contraindicated in patients with severe hypokalemia, severe hypomagnesemia, long QT syndrome, or in patients with a history of ventricular arrhythmias or torsades de pointes. (dsiaccesscentral.com)

This is a case of drug-induced torsades de Pointes (TDP) ventricular arrhythmia due to sotalol. (acc.org)

This leads to a further delay in repolarization and causes early afterdepolarization (EAD), the triggering event for torsade. (medscape.com)
This extended period of repolarization allows for early after-depolarizations that trigger torsades de pointes. (acc.org)

Recurrent metabolic crises with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration (MECRCN) is an autosomal recessive disorder characterized by episodic metabolic degeneration affecting skeletal muscle, cardiac muscle, and the nervous system. (nih.gov)

Torsades de pointes, torsade de pointes or torsades des pointes (TdP) (/tɔːˌsɑːd də ˈpwæ̃t/, French: [tɔʁsad də pwɛ̃t̪], translated as "twisting of peaks") is a specific type of abnormal heart rhythm that can lead to sudden cardiac death. (wikipedia.org)

In torsade, the morphology of the QRS complexes varies from beat to beat. (medscape.com)

PURPOSE: A case of loperamide-induced recurrent torsades de pointes is reported to raise awareness of an increasingly common phenomenon that could be encountered by medical providers during the current opioid epidemic. (bvsalud.org)
CONCLUSION: A 40-year-old male who developed torsades de pointes from loperamide overdose effectively treated with overdrive pacing, isoproterenol, and methylnatrexone. (bvsalud.org)

The long QT interval responsible for torsades de pointes ventricular tachycardia (TdeP VT) can be acquired, congenital or a combination. (msdmanuals.com)
The few electrocardiographically documented cases of syncope or sudden death in patients with a congenital LQTS have been characterized by torsades de pointes. (radcliffecardiology.com)

The patient had prolonged QTc and 2 episodes of torsades de pointes (TdP) that resulted in cardiac arrest with return of spontaneous circulation. (bvsalud.org)

Torsades de pointes and cardiac arrest have occurred in patients receiving VANFLYTA. (dsiaccesscentral.com)
Of the 1,081 patients with AML treated with VANFLYTA in clinical trials, torsades de pointes occurred in approximately 0.2% of patients, cardiac arrest occurred in 0.6% of patients, including 0.4% with a fatal outcome, and 0.1% of patients experienced ventricular fibrillation. (dsiaccesscentral.com)

With discontinuation of the erythromycin and aggressive repletion of the magnesium and potassium, no further torsade de pointes occurred and the patient's QT interval returned to normal. (medscape.com)

Rapidly recurrent despite electrical biphasic defibrillation. (medscape.com)

For both the dose escalation and expansion cohort phases of the study, eligible participants must have histologically confirmed advanced (locoregionally recurrent, not amenable to curative therapy) or metastatic solid tumors . (ucsd.edu)
Phase 1b Dose Escalation: Participants with histologically confirmed advanced locally (locoregionally recurrent, not amenable to curative therapy) or metastatic solid tumors. (ucsd.edu)

citation needed] Torsades occurs as both an inherited (linked to at least 17 genes) and as an acquired form caused most often by drugs and/or electrolyte disorders that cause excessive lengthening of the QT interval. (wikipedia.org)

Certain drugs and combinations of drugs resulting in drug interactions are common contributors to torsades de pointes risk. (wikipedia.org)

Cordarone and other forms of amiodarone are not approved to treat atrial fibrillation, and are only indicated as "a drug of last resort for patients suffering from documented recurrent life-threatening ventricular fibrillation and ventricular tachycardia. (rxinjuryhelp.com)

Six days later, the patient developed recurrent presyncope, ultimately culminating in an abrupt episode of syncope just after showering at a rehabilitation center. (acc.org)

Pacerone (amiodarone HCl) is an antiarrhythmic drug indicated for treatment of recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia only when these conditions have not responded to documented adequate doses of other available antiarrhythmics or when alternative agents could not be tolerated. (rxlist.com)

QT-prolonging medications such as clarithromycin, levofloxacin, or haloperidol, when taken concurrently with cytochrome P450 inhibitors, such as fluoxetine, cimetidine, or particular foods including grapefruit, can result in higher-than-normal levels of medications that prolong the QT interval in the bloodstream and therefore increase a person's risk of developing torsades de pointes. (wikipedia.org)
Other factors such as a history of heart failure or coronary heart disease, hypokalemia, hypomagnesemia, and the concomitant use of other QT prolonging drugs may also contribute to the risk of torsades. (acc.org)

O coração é composto por três tipos de músculo: atrial, ventricular e das fibras especializadas excitatórias e condutoras. (bvsalud.org)

Si desea crear un gráfico de barras básico 8 tipos de cuadros y gráficos de Excel y cuándo usarlos 8 tipos de cuadros y gráficos de Excel y cuándo usarlos Los gráficos son más fáciles de comprender que el texto y los números. (unedose.fr)

Cuando trabajas con un documento de Excel grande, a veces puede ser un proceso complicado y lento solo para navegar a los datos que necesitas. (unedose.fr)
En un documento en blanco, presionando CTRL + una tecla de flecha simplemente lo llevará a sus límites externos, pero en una hoja de cálculo poblada es mucho más útil. (unedose.fr)

El uso de filtros puede ser una bendición cuando se trabaja con una hoja de cálculo grande, particularmente si tiene dificultades para encontrar datos clave 4 Funciones de búsqueda de Excel para buscar hojas de cálculo de manera eficiente 4 Funciones de búsqueda de Excel para buscar hojas de cálculo de manera eficiente Buscar una hoja de cálculo de Excel grande no siempre fácil. (unedose.fr)

We discuss a case who had amiodarone-induced incessant Torsades de Pointes (TdP), that could only be suppressed by lidocaine. (uwi.edu)

The dispersion of refractoriness permits propagation of the early after-depolarizations and initiation of torsade de pointes ventricular tachycardia. (msdmanuals.com)

Do ponto de vista fisiológico e fisiopatológico os estados conformacionais do canal de sódio constitui-se um importante aspecto para o diagnóstico e tratamento de doenças cardíacas. (bvsalud.org)

Os mecanismos da excitabilidade celular e de propagação dos sinais elétricos no músculo cardíaco são de grande importância funcional e patológica. (bvsalud.org)

This was symbolically termed torsade de pointes, or "twisting of the point" about the isoelectric axis, because it reminded the authors of the torsade de pointes movement in ballet. (medscape.com)

In one example, the gastrokinetic drug cisapride (Propulsid) was withdrawn from the US market in 2000 after it was linked to deaths caused by long QT syndrome-induced torsades de pointes. (wikipedia.org)

If in doubt, treat as Torsades de Pointes (esp. (fpnotebook.com)

The etiology and management of torsade are, in general, quite different from those of garden-variety VT. (medscape.com)

In particular, the use of group IA antidysrhythmic drugs, which tend to prolong the QT interval, can have disastrous consequences in torsade. (medscape.com)

This shows an example of recurrent nonsustained torsade de pointes that occurred several hours after the ECG was performed. (medscape.com)

Anatomy4

Organisms2

Diseases16

Chemicals and Drugs35

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Phenomena and Processes2

Disciplines and Occupations1

Polymorphic10

Prolonged QT inter3

Prolongation2

Ventricular arrhythmias2

Arrhythmia1

Repolarization2

Arrhythmias1

Sudden cardi1

Morphology1

Loperamide2

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Cardiac arrest2

Magnesium1

Defibrillation1

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Antiarrhythmic1

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Atrial1

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