• mRNA
  • Report improved antitumoral NK-cell activity in DC-based vaccine strategies through the use of IL-15 (show IL15 ELISA Kits )/IL-15Ralpha mRNA-engineered designer DC. (antibodies-online.com)
  • IL-15 has also been found to play a critical role in the development and survival of NK cells and CD8+ T cells.Although high levels of mouse IL-15 mRNA have been observed in many cell types, free IL-15 is rarely detectable in biological samples. (fishersci.no)
  • 1998). "Cotranscription and intergenic splicing of human galactose-1-phosphate uridylyltransferase and interleukin-11 receptor alpha-chain genes generate a fusion mRNA in normal cells. (wikipedia.org)
  • expression
  • This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. (wikipedia.org)
  • The human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surface. (nih.gov)
  • Proliferation response to interleukin-2 and Jak/Stat activation of T cells immortalized by human T-cell lymphotropic virus type 1 is independent of open reading frame I expression. (nih.gov)
  • IL-15 and IL-15 Receptor alpha are expressed by dendritic cells and macrophages in response to inflammatory stimuli.Our testing suggests that there may be strain differences in expression and staining of the Mouse IL-15 Receptor alpha. (fishersci.no)
  • The proliferation observed in cells stimulated with IL-2 primarily occurred in a subset of the CD70 + CD8 + T cells that up-regulated IL-2 receptor expression but did not occur in CD70 − CD8 + T cells. (jimmunol.org)
  • however, expression of CD27 is down-regulated in late effector stage T cells ( 14 , 15 , 16 , 17 ). (jimmunol.org)
  • Interleukin 33 (IL-33) induces IL-9 expression and secretion in T cells, which was confirmed by the results obtained in mice by using Human in vitrosystem. (wikipedia.org)
  • IL15
  • Interleukin-15 (IL15) is a cytokine produced by normal brain, but the functions of the IL15 system in normal adults are not yet clear. (jneurosci.org)
  • The immunomodulatory cytokine interleukin-15 (IL15) is ubiquitously present in the normal CNS as well as other organs ( Maślińska, 2001 ). (jneurosci.org)
  • Based on the abundance of IL15 and its specific receptor IL15Rα in the hippocampus, we tested the hypothesis that IL15 facilitates hippocampal-dependent memory consolidation. (jneurosci.org)
  • In a mouse autoimmune model of multiple sclerosis, experimental autoimmune encephalomyelitis (EAE), there is a robust upregulation of IL15Rα, the specific receptor for IL15, in different CNS regions. (jneurosci.org)
  • IRF-1 (show IRF1 ELISA Kits ) promotes LTx I/R injury via hepatocyte IL-15 (show IL15 ELISA Kits )/IL-15Ralpha production and suggest that targeting IRF-1 (show IRF1 ELISA Kits ) and IL-15 (show IL15 ELISA Kits )/IL-15Ralpha may be effective in reducing I/R injury associated with LTx. (antibodies-online.com)
  • epicardial fat may be a potential source of both IL-15 (show IL15 ELISA Kits ) and IL-15Ralpha. (antibodies-online.com)
  • Spontaneous cage activity was not different and IL-15 (show IL15 ELISA Kits ) protein levels were lower in male and female mIl15ra( fl/fl (show FLT3LG ELISA Kits ))/Cre(+) mice. (antibodies-online.com)
  • Primary myogenic cultures require IL-15RA to respond to IL-15 (show IL15 ELISA Kits ). (antibodies-online.com)
  • we found that aging-related functional NK cell deficiency was completely reversed by injecting soluble IL-15 (show IL15 ELISA Kits )/IL-15Ralpha complexes. (antibodies-online.com)
  • Auf www.antikoerper-online.de finden Sie aktuell 320 Interleukin 15 (IL15) Antikörper von 34 unterschiedlichen Herstellern. (antikoerper-online.de)
  • neutrophils
  • These receptors are generally found on human neutrophils, a type of white blood cell of the myeloid lineage, with approximately 65,000 receptors per neutrophil. (wikipedia.org)
  • The reported size of the translated protein is approximately 40kD, differing from the native purified receptors from the surface of neutrophils by 20kD. (wikipedia.org)
  • signals
  • Proper T cell function relies on the integration of signals delivered by Ag, cytokine, and costimulatory receptors. (jimmunol.org)
  • Without important developmental signals from IL-7 and IL-15, T-cell and NK cell populations respectively fail to develop. (wikipedia.org)
  • antigen
  • The adaptive immune system has evolved antigen receptor diversity to cope with a large variety of pathogens and non-self antigens. (frontiersin.org)
  • Broadly, ILCs are defined by their lymphoid lineage and their lack of RAG-mediated recombined antigen receptors. (frontiersin.org)
  • Antibody
  • Staining has also been observed with this antibody after pre-incubation of NK cells with exogenous Mouse IL-15/IL-15R Complex, suggesting that DNT15Ra will recognize both Mouse IL-15 Receptor alpha and the Mouse IL-15/IL-15R Complex.Applications Reported: This DNT15Ra antibody has been reported for use in flow cytometric analysis.Applications Tested: This DNT15Ra antibody has been tested by flow cytometric analysis of mouse dendriric cells. (fishersci.no)
  • Approved anti-IL17(R) drugs include : Brodalumab (Siliq), an antibody to the receptor, approved for psoriasis. (wikipedia.org)
  • Ixekizumab, approved for plaque psoriasis, is an antibody to IL-17 itself (rather than the receptor). (wikipedia.org)