Receptors species of bacteria biofilm oral fusobacterium. Medical search. Frequent questions

The inflammation is primarily localized to the gum but penetrates deeper if left untreated, creating pockets that host anaerobic bacteria which can then lead to further erosion of the tooth attachment and eventually to tooth loss. (encyclopedia.pub)
Research has shown a direct correlation between the amount of coating on a person's tongue and the total number of anaerobic bacteria present in the coating. (medscape.com)

The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)
Fusobacterium nucleatum plays a key role in creating the pathogenic subgingival biofilm that initiates destructive periodontitis. (nature.com)
Periodontitis is a highly prevalent, chronic multifactorial infectious disease, induced by the dysbiotic biofilm that triggers a persistent systemic inflammation and recurrent bacteremia. (intechopen.com)
This chapter emphasis the relationship between periodontitis and adverse pregnancy outcomes and the underlying mechanisms that link peridontitis to oral carcinogenesis. (intechopen.com)
In periodontitis, however, the development of periodontal pockets as a result of breakdown of the bone and soft-tissues supporting the teeth, creates a new subgingival niche that promotes growth of bacterial species suited to the environment. (biomedcentral.com)
In addition, dental biofilm, especially subgingival plaque in patients with periodontitis, has been associated with cardiovascular and respiratory disease and diabetes mellitus, and recently constituting a high risk for developing severe illness due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection [ 2 ] . (encyclopedia.pub)
Periodontitis is a complex, chronic inflammatory disease caused by an abnormal host response to bacteria from dental plaque. (encyclopedia.pub)
The abundance of #Porphyromonadaceae and #Fusobacterium , which are co-pathogens in periodontitis and intestinal inflammation was significantly enriched in the gut of the C-SP group. (metabiom.org)

The problem of elucidating the human microbiome is essentially identifying the members of a microbial community, which includes bacteria, eukaryotes, and viruses. (wikipedia.org)
Adverse microbial changes, both in composition and function, can act at several levels within the gut (stool and mucosal) and have also been described in the blood and oral cavity. (jci.org)
The human oral cavity is a highly complex ecosystem in which the tooth- and soft-tissue surfaces offer distinct ecological niches for microbial colonization. (biomedcentral.com)
Oral malodor is primarily the result of microbial metabolism. (medscape.com)
About 80-90% of halitosis is due to intraoral microbial species that populate on the tongue, teeth, and periodontal biofilms. (medscape.com)
Several studies have illustrated the therapeutic efficacy of photoactivated riboflavin against nosocomial infections and multidrug resistant bacterial infections as well as microbial associated biofilm infections, revealing the potential role of riboflavin as a promising antimicrobial candidate, which could serve as one of the alternatives in fighting the global crisis of the emergence of antimicrobial resistance seen in different pathogenic microbes. (bioseek.eu)
Hence, this review aimed to provide some insights on the promising role of riboflavin as an antimicrobial candidate and also a host immune-modulator from a multi-perspective view as well as to discuss the application and challenges on using riboflavin in photodynamic therapy against various pathogens and microbial biofilm-associated infections. (bioseek.eu)

Some members of the genera #Porphyromonas , #Prevotella , and #Tannerella are well-known pathogens of the oral cavity, where they can notably cause periodontal disease and dental #Caries . (metabiom.org)
Besides maintaining human health, different sources reported that riboflavin can inhibit or inactivate the growth of different pathogens including bacteria, viruses, fungi and parasites, highlighting the possible role of riboflavin as an antimicrobial agent. (bioseek.eu)

They also prevented biofilm formation by F. nucleatum at concentrations that did not interfere with bacterial growth. (nature.com)
In addition, the treatment of a pre-formed F. nucleatum biofilm with the green tea extract and EGCG caused a time-dependent decrease in biofilm viability. (nature.com)
The green and black tea extracts, EGCG, and theaflavins decreased the adherence of F. nucleatum to oral epithelial cells and matrix proteins. (nature.com)
Moreover, these tea components also attenuated F. nucleatum -mediated hemolysis and hydrogen sulfide production, two other virulence factors expressed by this bacterium. (nature.com)
Given its central role in biofilm formation, F. nucleatum may represent a key target for controlling biofilm formation. (nature.com)
A. oris induces the coaggregation of the early colonizers Streptococcus gordonii and Streptococcus sanguinis with the intermediate colonizer Fusobacterium nucleatum in oral biofilms [ 1 ]. (biomedcentral.com)
A model multi-species sub-gingival community containing Fusobacterium nucleatum, Streptococcus constellatus , Parvimonas micra with wild type or isogenic mutants of P. gingivalis was then created and growth and proteolytic activity in serum assessed as above. (biomedcentral.com)

Recently, the more appropriate term microbiota is applied, though its use has not eclipsed the entrenched use and recognition of flora with regard to bacteria and other microorganisms. (wikipedia.org)
Similar to the effect of gut microbiota on cirrhosis, emerging evidence also suggests that there is a possible link between a dysbiotic oral microenvironment and liver diseases. (jci.org)
Their mechanisms include maintaining physicochemical conditions in the colon (e.g., pH and bile acid profile), balancing the quantity of beneficial gut microbiota members through the production of short-chain fatty acids, reducing the abundance of putrefactive bacteria producing enzymes such as azoreductase, β-glucosidase, β-glucuronidase, and nitroreductase, binding and degrading mutagenic compounds, as well as performing immunomodulatory activities. (metabiom.org)
Although the gut microbiota is populated mainly by bacteria, it also contains less than 1% of fungi. (frontiersin.org)

The development of antibiotic resistance in periodontopathogens is a major issue given that these bacteria may migrate from the oral cavity to other organs where they may cause infections or transfer their antibiotic resistances to other bacterial species. (nature.com)
While dysbiosis in the oral cavity could be a source of systemic inflammation, current cirrhosis treatment modalities are targeted toward the gut-liver axis and do not address the oral microbiome. (jci.org)
Definition Dental Plaque "is a specific but highly variable structural entity, resulting from sequential colonization of microorganisms on tooth surfaces, restorations & other parts of oral cavity, composed of salivary components like mucin, desquamated epithelial cells, debris & microorganisms, all embedded in extracellular gelatinous matrix. (medicpresents.com)

It plays a key role in subgingival biofilm formation by bridging the early colonizers (streptococci and actinomyces) and the late colonizers ( Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola ) 3 that make up the red complex initially described by Socransky et al . (nature.com)
Together in the subgingival consortium however, all the included species were able to grow in the serum environment and the community adopted a proteolytic phenotype. (biomedcentral.com)
Dysbiotic subgingival communities are characterized by a relative increase in abundance of anaerobic, Gram-negative bacterial species that can exploit protein-rich GCF as a nutrient source, promoting development of a proteolytic community phenotype. (biomedcentral.com)

This study revealed a marked impact of appendectomy on gut bacteria and fungi, which was particularly durable for fungi. (frontiersin.org)

Presence of plaque rich in bacteria (especially Streptococcus mutans ) directly destroys the enamel layer by dissolving tooth minerals (mainly hydroxyapatite, Ca 10(PO 4) 6(OH) 2) resulting in caries. (encyclopedia.pub)

Among the vast variety of bacteria, only very few are considered pathogenic and cause disease in humans. (amboss.com)

Dysbiotic communities are characterized by increased numbers of bacteria that exploit the serum-like transudate for nutrients, giving rise to a proteolytic community phenotype. (biomedcentral.com)

It allows the leakage of Gram-negative anaerobic species into the systemic bloodstream followed by bacteremia. (encyclopedia.pub)

The number of bacterial genes (assuming 1000 bacterial species in the gut with 2000 genes per species) is estimated to be 2,000,000 genes, 100 times the number of approximately 20,000 human genes. (wikipedia.org)
The mouth is home to hundreds of bacterial species with various nutritional preferences. (medscape.com)

Analysis showed that the gut bacterial composition of samples from HwA was less diverse than that of samples from HwoA and had a lower abundance of Roseburia , Barnesiella , Butyricicoccus , Odoribacter , and Butyricimonas species, most of which were short-chain fatty acids-producing microbes. (frontiersin.org)

In bacteria and archaea , structural proteins with related functions are usually encoded together within the genome in a block called an operon and are transcribed together under the control of a single promoter , resulting in the formation of a polycistronic transcript ( Figure 12.30 ). (pressbooks.pub)

Organic Component Organic constituents : polysaccharides, proteins, glycoproteins, and lipid material Polysaccharides produced by bacteria-Dextran: predominant form Albumin: originating from crevicular fluid Lipid material: debris from the membranes of disrupted bacterial and host cells and possibly food debris. (medicpresents.com)

In recombinant DNA technology, DNA molecules are manipulated using naturally occurring enzymes derived mainly from bacteria and viruses. (pressbooks.pub)

This method is used to eliminate or inhibit gingival bacteria flora, decrease inflammation, and help to discontinue bone desorption. (encyclopedia.pub)

Actinomyces oris is an early colonizer and has two types of fimbriae on its cell surface, type 1 fimbriae (FimP and FimQ) and type 2 fimbriae (FimA and FimB), which contribute to the attachment and coaggregation with other bacteria and the formation of biofilm on the tooth surface, respectively. (biomedcentral.com)

Dental plaque, which leads to oral diseases, may be a risk factor causing a severe course of COVID-19 similar to those in above mentioned chronic diseases. (encyclopedia.pub)

Moreover, riboflavin and flavins could produce reactive oxygen species (ROS) when exposed to light, inducing oxidative damage in cells and tissues, and thus are excellent natural photosensitizers. (bioseek.eu)

isolates, while the role of cell-free supernatants, from diverse bacteria, in inducing enhanced adherence was investigated using microtitre plate assays. (biomedcentral.com)

To overcome these difficulties, controlled drug delivery systems have been evolved as an alternative method to address oral infectious disease ailments. (encyclopedia.pub)
Recently, there has been growing interest in controlled drug delivery systems as a whole and as a potential method to address oral infectious disease ailments in particular [ 8 ] . (encyclopedia.pub)

The current treatment of periodontal disease involves oral hygiene such as mechanical cleaning (brushing and flossing), together with the use of dentifrices and antibacterial mouthwashes. (encyclopedia.pub)
[ 8 ] In people with rigorous oral hygiene, good dentition and a healthy periodontium, the main cause of bad breath (halitosis) is likely to be the back of the tongue. (medscape.com)

Their ability to exist as biofilm structures has been alluded to but not extensively investigated. (biomedcentral.com)
The ability of E. meningoseptica isolates to adhere to abiotic surfaces and form biofilm structures may result from the hydrophilic cell surface and multiple adhesins located around the cell. (biomedcentral.com)

May involve the interaction of phosphate groups with calcium ions in saliva to form "bridges" Protective functions of early enamel pellicle: protection , lubrication by decreasing frictional forces, may selectively concentrate antimicrobial substances such as immunoglobulins, lysozyme, and cystatins at different oral surfaces. (medicpresents.com)
Most of them attach to different surfaces to form some type of biofilm matrix that is highly structured and spatially organized. (encyclopedia.pub)

E. meningoseptica is the most significant species for human clinical infections, although E. miricola has been associated with sepsis [ 2 ]. (biomedcentral.com)

At junctional epithelium the teeth provide access to bacteria into the body. (medicpresents.com)

Formation of dental Pellicle Acquired enamel pellicle forms rapidly - Early pellicle Characterized by an absence of bacteria and their products. (medicpresents.com)
E. meningoseptica isolates CH2B and NCTC 10016 T demonstrated stronger biofilm formation in nutrient-rich medium compared to nutrient-poor medium at both 21 and 37°C, respectively. (biomedcentral.com)
If not removed regularly, the biofilm undergoes maturation, which is connected with a progressive shift from a Gram-positive to a Gram-negative anaerobic species, which results in formation under the gingival surface, where bacteria grow profusely [ 1 ] . (encyclopedia.pub)

SCFAs affect the INAC-associated activities of the A. oris fimbrillins and non-fimbrillins during ionized and non-ionized acid formations in the form of co-culturing with other bacteria in the dental plaque but not impact the interaction of A. oris with streptococci. (biomedcentral.com)

E. meningoseptica isolate CH2B and strain NCTC 10016 T displayed a strong biofilm-forming phenotype which may play a role in its potential pathogenicity in both clinical and aquaculture environments. (biomedcentral.com)

The aim of this review article is to highlight the role of gut microbiome and inflammation in the pathophysiology of cirrhosis and to introduce the oral-gut-liver axis as a new perspective to consider in future research. (jci.org)

It was shown that 40-50% of plaque remains after tooth brushing, and the effects of biofilm retention are clearly evident in the prevalence of caries, gingivitis and periodontal disease. (encyclopedia.pub)
Patients with RA and periodontal disease experienced repeated oral bacteremias associated with transcriptional signatures of specific monocytes, recently identified in inflamed RA synovia and blood of those with RA flares. (metabiom.org)

therefore, this review will highlight the emerging role of the oral-gut-liver axis and introduce perspectives for future research. (jci.org)
The role of volatile sulfur compounds (VSCs) in producing bacteria that colonize the dorsal surface of the tongue was recently understood as a primary cause of halitosis (bad breath). (medscape.com)

There are several beneficial species of bacteria and potential probiotics present in breast milk. (wikipedia.org)
Instead of oral administration, probiotics can also be delivered locally at tumor sites, which can reduce non-specific pharmacological effects on non-tumor tissues. (metabiom.org)

Biofilm architecture of isolate CH2B alone as well as in co-culture with Listeria monocytogenes was investigated using flow cells and microscopy. (biomedcentral.com)
The oral bacteria observed transiently in blood were broadly citrullinated in the mouth, and their in situ citrullinated epitopes were targeted by extensively somatically hypermutated ACPA B Cells encoded by RA blood plasmablasts. (metabiom.org)
heat-inactivated PD-associated total bacteria and #Klebsiella variicola increased the expression of TNFα, IL-1β, #IL-6 , TLR2, and TLR9 in microglial cells. (metabiom.org)

Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
It can be a social problem in which standard dental treatments and mouthwashes are often recommended to manage oral causes and provide relief that often needs consistent maintenance. (medscape.com)

Given the emergence of antibiotic-resistant bacteria, new, preferably inexpensive, alternatives to conventional antibiotics must be developed. (nature.com)

[8] The bacteria are spread to humans through animal urine , or water and soil contaminated with animal urine, coming into contact with the eyes , mouth, nose or breaks in the skin . (mdwiki.org)

If the DNA that is introduced comes from a different species, the host organism is now considered to be transgenic. (pressbooks.pub)

In the multi-species consortium, growth was facilitated by the wild-type and Rgp-expressing strains of P. gingivalis, suggesting that Rgp is involved in delivery of nutrients to the whole community through degradation of complex protein substrates in serum. (biomedcentral.com)
#Bifidobacterium is associated with antitumor effects, and oral administration of #Bifidobacterium alone improved tumor control to the same degree as PD-L1 antibody therapy while combination treatment nearly abolished tumor growth in mice. (metabiom.org)

He and coworkers established that oral malodor (bad breath) is associated with the presence of volatile sulfur compounds, primarily hydrogen sulfide and methylmercaptan. (medscape.com)

In patients with AD, oral bacteria were detected in brain tissues, and increased levels of pro-inflammatory cytokines were also detected. (metabiom.org)

#Probiotic (Bifidobacter and Lactobacilus) ] - Certain probiotic bacteria reportedly demonstrated effects in suppressing and regressing cancer . (metabiom.org)

Species of the genus Copaifera have pharmacological properties favorable for wound treatment: control of inflammatory pain, reduction of inflammatory reaction, tissue reepithelialization and repair, angiogenesis, wound retraction and scar remodeling. (bvsalud.org)

Microscopy (with staining) and culture are the most important methods of identifying bacteria. (amboss.com)

As interventions designed to modulate oral dysbiosis may delay progression of cirrhosis, a better understanding of this process is of the utmost importance. (jci.org)

Anatomy2

Organisms21

Diseases8

Chemicals and Drugs8

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes8

Information Science2

Anaerobic bacteria2

Periodontitis8

Microbial7

Pathogens2

Nucleatum7

Microbiota4

Cavity3

Subgingival3

Fungi1

Streptococcus1

Pathogenic1

Dysbiotic1

Bacteremia1

Bacterial species2

Abundance1

Archaea1

Proteins1

Viruses1

Inhibit1

Actinomyces1

Chronic1

Reactive oxygen1

Adherence1

Infectious disease2

Hygiene2

Structures2

Surfaces2

Infections1

Teeth1

Formation3

Streptococci1

Clinical1

Microbiome1

Periodontal disease2

Role2

Probiotics2

Cells3

Dental2

Antibiotics1

Humans1

Host1

Growth2

Presence1

Patients1

Effects1

Treatment1

Important1

Progression1