• D-erythroascorbate peroxidase-deficient cells have remarkably increased intracellular reactive oxygen species and methylglyoxal independent of the intracellular D-erythroascorbate content, which leads to activation of catalase-peroxidase and cytochrome c peroxidase, resulting in defects in cell growth, viability, mitochondrial respiration, filamentation and virulence. (brenda-enzymes.info)
  • LA chelates redox-active transition metals, thus inhibiting the formation of hydroxyl radicals and also scavenges reactive oxygen species (ROS), thereby increasing the levels of reduced glutathione. (weeksmd.com)
  • In the recognition and response process of phagocytosis, reactive oxygen species ROS and reactive nitrogen species RNS are produced [ 5 ] . (encyclopedia.pub)
  • The mechanisms of how NF-ƙB is activated is not yet well understood, however, recent research suggests that reactive oxygen species (ROS) may be involved. (osri.asia)
  • Reactive oxygen species (ROS) have recently been suggested to be involved in the signal transduction pathway which leads to the activation of NF-ƙB and subsequent HIV-1 activation. (osri.asia)
  • Reactive oxygen species (ROS) were detected by flow cytometry, using the ROS-specific fluorescent indicator. (go.jp)
  • Physiological levels of reactive species (ROS and RNS) are important in cellular signaling, but higher concentrations and prolonged exposure can fight infections by damaging important microbial biomolecules [ 6 ] . (encyclopedia.pub)
  • Hypochlorous acid HOCl and hypothiocyanous acid HOSCN synthesized through the enzyme myeloperoxidase MPO, which catalyzes the reaction between H 2 O 2 and Cl − or SCN − , are important inorganic bactericidal molecules, effective against a wide range of microbes. (encyclopedia.pub)
  • The Avidin-Biotin system has been utilized extensively for enzyme-linked immuno solid-phase assay (ELISA), in which an enzyme-Avidin conjugate (useful for detection by reaction with the enzyme's substrate to afford a colored or chemiluminescent product) is employed to detect the presence of a biotinylated antibody, after first binding the antibody to an immobilized antigen or hapten. (justia.com)
  • Ibuprofen and lipoic acid diamide as co-drug with neuroprotective activity: pharmacological properties and effects in beta-amyloid (1-40) infused Alzheimer's disease rat model. (weeksmd.com)
  • Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity. (weeksmd.com)
  • This is particularly important with the Diamide group of insecticides (IRAC group 28). (arizona.edu)
  • These reactive radicals possibly induced the death of S. cerevisiae cells. (go.jp)
  • The chemical changes mediated by reactive species RS are detrimental to cell function because they cause oxidation and nitration, altering the structures of cellular proteins, DNA, and lipids, and impairing their normal function. (encyclopedia.pub)
  • Its activity as an inhibitor of inflammation counteracts reactive astrogliosis induced by beta-amyloid peptide, in a model relevant for neurodegeneration, probably via the PPAR-α mechanism of action. (wikipedia.org)
  • It is known that nitroglycerin gtn can be converted to form a nitric oxide no molecule which is a highly reactive and unstable free radical species. (web.app)
  • Reactive oxygen species (ROS) are generated in the stepwise one-electron reduction of molecular oxygen during the respiration. (uni-greifswald.de)
  • To cope with these reactive species, bacteria have evolved different defense and repair mechanisms. (uni-greifswald.de)
  • 2. Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production. (nih.gov)
  • This could be due to reduced synthesis, decreased activity, and/or impaired secretion of the enzyme. (jci.org)
  • Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. (planteome.org)
  • Its activity as an inhibitor of inflammation counteracts reactive astrogliosis induced by beta-amyloid peptide, in a model relevant for neurodegeneration, probably via the PPAR-α mechanism of action. (wikipedia.org)
  • The results involving metformin on endometriotic muscle had been at the very least comparable to letrozole.Intestinal tract inflammation comes with extreme manufacture of reactive oxygen and also nitrogen radical varieties because of the massive infiltration regarding polymorphonuclear along with mononuclear leukocytes. (dub-receptor.com)