This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. (wikipedia.org)
Woehl, E. and Dunn, M.F. Mechanisms of monovalent cation action in enzyme catalysis: the tryptophan synthase α-, β-, and αβ-reactions. (enzyme-database.org)
In enzymology, a GDP-mannose 4,6-dehydratase (EC 4.2.1.47) is an enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. (creative-biolabs.com)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). (cam.ac.uk)
Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed. (cam.ac.uk)
Dehydratase1
1975. [Intermediate plateaux in kinetics of the reaction catalyzed by biodegradative L-threonine dehydratase from Escherichia coli]. . (umass.edu)
Succinate1
This reaction releases succinate (a TCA cycle intermediate) and CO2. (lbl.gov)
Synthase1
Other names in common use include: β-thionase, cysteine synthase, L-serine hydro-lyase (adding homocysteine), methylcysteine synthase, serine sulfhydrase, and serine sulfhydrylase. (wikipedia.org)
Enzymatic1
Crystal structures of yCBS-cc in complex with enzymatic reaction intermediates have been captured, providing a structural basis for residues involved in catalysis. (rhea-db.org)
Rhea1
Search chemical reactions in Rhea for this molecule. (rhea-db.org)
Substrates2
Reaction view is shown in the form of scheme showing corresponding substrates (blue) and products (red). (e-cyanobacterium.org)
There are two types of entities in reaction - substrates and products. (e-cyanobacterium.org)
Intermediates1
In analogy with other β-replacement enzymes, the reaction catalyzed by CBS is predicted to involve a series of adoMet-bound intermediates. (wikipedia.org)
Carbon1
Engineered electroactive microbes could address many of the limitations of current energy storage technologies by enabling rewired carbon fixation, a process that spatially separates reactions that are normally carried out together in a photosynthetic cell and replaces the least efficient with non-biological equivalents. (biomedcentral.com)
External1
Addition of serine results in a transchiffization reaction, which forms of an external aldimine. (wikipedia.org)
Pectin1
Unique pecti-nase prepa-ra-tion with high poly-galac-tur-onase ( PG ) to pectin lyase ( PL ) ratio for effec-tive diges-tion of sol-u-ble and insol-u-ble pectins to improve the yields in juice extraction. (biocatalysts.com)
Serine sulfhydrase1
Other names in common use include: β-thionase, cysteine synthase, L-serine hydro-lyase (adding homocysteine), methylcysteine synthase, serine sulfhydrase, and serine sulfhydrylase. (wikipedia.org)
Homocysteine2
Transsulfuration, catalyzed by CBS, converts homocysteine to cystathionine, which cystathione gamma lyase converts to cysteine. (wikipedia.org)
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. (nih.gov)
Enzymes1
In analogy with other β-replacement enzymes, the reaction catalyzed by CBS is predicted to involve a series of adoMet-bound intermediates. (wikipedia.org)
Hydrogen1
In order to find the most probable mechanisms of scavenging these radicals, different types of reactions such as one and two hydrogen atom transfer (HAT), single electron transfer (SET) and sequential proton loss electron transfer (SPLET) processes were investigated. (springer.com)
KEGG3
Reactions in KEGG database that match this reaction. (umassmed.edu)
Reaction directionality scores for the KEGG reaction(s) that are associated with this model reaction . (umassmed.edu)
Different sources are used and evidence is culminated for each direction with respect to the KEGG reaction (click reaction IDs to reach relevant KEGG pages). (umassmed.edu)
Porphobilinogen synthase1
The porphobilinogen synthase catalyzed reaction mechanism. (medlineplus.gov)
Pathway2
CBS catalyzes the bio-chemical condensation reactions in the transsulfuration pathway. (nih.gov)
In some cases, a score of 0 also indicates flux carrying as part of a looping pathway, as a looping flux flow does not warrant the contribution of the reaction to metabolic processes in a comparment. (umassmed.edu)
Mitochondria1
Each predictor is used to determine whether the reaction takes place in mitochondria or other compartment. (umassmed.edu)
Compartment1
Score shows whether the reaction is useful when it is placed in the indicated compartment based on flux balance analysis . (umassmed.edu)