Rationale drugs drug screening assays antitumor. Medical search. Frequent questions

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Anatomy17

Cell Line, Tumor Tumor Cells, Cultured T-Lymphocytes, Cytotoxic CD8-Positive T-Lymphocytes Dendritic Cells Killer Cells, Natural Lymphocytes, Tumor-Infiltrating T-Lymphocytes Cells, Cultured Cell Line CD4-Positive T-Lymphocytes HT29 Cells T-Lymphocytes, Regulatory Spleen K562 Cells Macrophages Myeloid Cells

Organisms13

Mice, Nude Mice, Inbred BALB C Mice, Inbred C57BL Mice, SCID Oncolytic Viruses Adenoviridae Mice, Inbred DBA Streptomyces Mice, Transgenic Mice, Inbred C3H Mice, Knockout Mice, Inbred Strains Mice, Inbred ICR

Diseases42

Leukemia P388 Neoplasms, Experimental Sarcoma 180 Melanoma, Experimental Neoplasms Leukemia L1210 Carcinoma, Lewis Lung Lung Neoplasms Melanoma Colonic Neoplasms Sarcoma, Experimental Fibrosarcoma Disease Models, Animal Neovascularization, Pathologic Mammary Neoplasms, Experimental Breast Neoplasms Carcinoma, Ehrlich Tumor Ovarian Neoplasms Leukemia L5178 Adenocarcinoma Leukemia, Experimental Prostatic Neoplasms Neoplasm Metastasis Kidney Neoplasms Liver Neoplasms Brain Neoplasms Pancreatic Neoplasms Lymphoma Carcinoma, Renal Cell Glioma Mast-Cell Sarcoma Carcinoma, Hepatocellular Glioblastoma Liver Neoplasms, Experimental Skin Neoplasms Multiple Myeloma Neuroblastoma Carcinoma, Non-Small-Cell Lung Disease Progression Carcinoma, Squamous Cell Colorectal Neoplasms Head and Neck Neoplasms

Chemicals and Drugs103

Antineoplastic Agents Antibiotics, Antineoplastic Cancer Vaccines Enediynes Antineoplastic Agents, Phytogenic Antigens, Neoplasm Antibodies, Monoclonal Angiogenesis Inhibitors Doxorubicin Immunotoxins Interferon-gamma Cisplatin Indoles Prodrugs Interleukin-2 Ellipticines Protein Kinase Inhibitors Camptothecin Interleukin-12 Antineoplastic Agents, Alkylating Naphthacenes Enzyme Inhibitors Paclitaxel Topoisomerase I Inhibitors Pyrroles Quinazolines Intercalating Agents Zinostatin Pyrazines Antibodies, Neoplasm Recombinant Proteins Adjuvants, Immunologic Drug Carriers Plicamycin Pyrimidines Antibodies, Monoclonal, Humanized Boronic Acids Cytokines Liposomes Fluorouracil Pyridines Cyclophosphamide Aminoglycosides Aminoacridines Receptor, Epidermal Growth Factor Deoxycytidine Thiazoles Pyrazoles Phenylurea Compounds Amsacrine Neoplasm Proteins Histone Deacetylase Inhibitors Plant Extracts DNA Antimetabolites, Antineoplastic Benzoquinones Benzenesulfonates Receptor, erbB-2 Sulfonamides Membrane Glycoproteins Recombinant Fusion Proteins gp100 Melanoma Antigen Endostatins Taxoids Anthraquinones Mitomycin TOR Serine-Threonine Kinases Xanthones Antigens, CD80 Topoisomerase II Inhibitors Maytansine Depsipeptides Niacinamide Topotecan Antigens, CD Mitomycins Organoplatinum Compounds RNA, Messenger Acridines Nitrogen Mustard Compounds Lactones Proto-Oncogene Proteins c-akt Streptonigrin Hydroxamic Acids Naphthoquinones Vascular Endothelial Growth Factor A Immunoconjugates Tumor Necrosis Factor-alpha MART-1 Antigen Acronine DNA, Neoplasm Imidazoles Dioxoles Quinolines Piperazines Aziridines Vaccines, DNA Benzamides RNA, Small Interfering Tubulin Modulators Granulocyte-Macrophage Colony-Stimulating Factor Sirolimus Polyethylene Glycols

Analytical, Diagnostic and Therapeutic Techniques and Equipment53

Drug Screening Assays, Antitumor Xenograft Model Antitumor Assays Neoplasms, Experimental Neoplasm Transplantation Melanoma, Experimental Immunotherapy Immunotherapy, Adoptive Transplantation, Heterologous Genetic Therapy Injections, Intralesional Oncolytic Virotherapy Sarcoma, Experimental Tumor Burden Inhibitory Concentration 50 Disease Models, Animal Antineoplastic Combined Chemotherapy Protocols Flow Cytometry Treatment Outcome Drug Administration Schedule Research Design Mammary Neoplasms, Experimental Drug Evaluation, Preclinical Combined Modality Therapy Lymphocyte Activation Blotting, Western Drug Delivery Systems Immunotherapy, Active Injections, Intraperitoneal Drug Carriers Leukemia, Experimental Clinical Trials as Topic Transfection Administration, Oral Drug Design Immunohistochemistry Gene Transfer Techniques Transduction, Genetic Magnetic Resonance Spectroscopy Reverse Transcriptase Polymerase Chain Reaction Injections, Subcutaneous Drug Therapy, Combination Tumor Stem Cell Assay Lethal Dose 50 Infusions, Intravenous Molecular Targeted Therapy Maximum Tolerated Dose Liver Neoplasms, Experimental Adoptive Transfer Injections, Intravenous Clinical Protocols Models, Molecular Enzyme-Linked Immunosorbent Assay Lymphocyte Depletion

Psychiatry and Psychology1

Rationalization

Phenomena and Processes35

Drug Synergism Apoptosis Dose-Response Relationship, Drug Cell Proliferation Cell Survival Cytotoxicity, Immunologic Time Factors Inhibitory Concentration 50 Cell Division Genetic Vectors Molecular Structure Signal Transduction Drug Resistance, Neoplasm Structure-Activity Relationship Lymphocyte Activation Cell Cycle Cell Growth Processes Tumor Escape Gene Expression Regulation, Neoplastic Transfection Antibody-Dependent Cell Cytotoxicity Fermentation Transduction, Genetic Down-Regulation Tissue Distribution Phosphorylation Cell Death Tumor Microenvironment Immunity, Cellular Lethal Dose 50 Maximum Tolerated Dose Cell Movement Mutation Gene Expression Stereoisomerism

Disciplines and Occupations3

Research Design Drug Design Immunohistochemistry

Technology, Industry, Agriculture2

Liposomes Polyethylene Glycols

Information Science1

Molecular Sequence Data

Health Care3

Treatment Outcome Clinical Trials as Topic Clinical Protocols

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Technology, Industry, Agriculture Information Science Health Care

Drug Screening Assays, Antitumor Xenograft Model Antitumor Assays Antineoplastic Agents Cell Line, Tumor Mice, Nude Antibiotics, Antineoplastic Leukemia P388 Neoplasms, Experimental Neoplasm Transplantation Sarcoma 180 Melanoma, Experimental Cancer Vaccines Mice, Inbred BALB C Neoplasms Tumor Cells, Cultured Immunotherapy Mice, Inbred C57BL Leukemia L1210 Drug Synergism Apoptosis Dose-Response Relationship, Drug Cell Proliferation Immunotherapy, Adoptive Mice, SCID Enediynes Transplantation, Heterologous Antineoplastic Agents, Phytogenic Carcinoma, Lewis Lung Antigens, Neoplasm Genetic Therapy Antibodies, Monoclonal Injections, Intralesional Cell Survival Lung Neoplasms Melanoma Cytotoxicity, Immunologic Angiogenesis Inhibitors Oncolytic Virotherapy Colonic Neoplasms Sarcoma, Experimental T-Lymphocytes, Cytotoxic Tumor Burden CD8-Positive T-Lymphocytes Time Factors Dendritic Cells Fibrosarcoma Oncolytic Viruses Adenoviridae Inhibitory Concentration 50 Disease Models, Animal Cell Division Killer Cells, Natural Doxorubicin Antineoplastic Combined Chemotherapy Protocols Neovascularization, Pathologic Flow Cytometry Treatment Outcome Lymphocytes, Tumor-Infiltrating Genetic Vectors Molecular Structure Signal Transduction Drug Administration Schedule Immunotoxins Research Design Mice, Inbred DBA Mammary Neoplasms, Experimental Drug Evaluation, Preclinical Interferon-gamma Combined Modality Therapy Cisplatin T-Lymphocytes Indoles Drug Resistance, Neoplasm Prodrugs Interleukin-2 Ellipticines Protein Kinase Inhibitors Streptomyces Camptothecin Structure-Activity Relationship Interleukin-12 Antineoplastic Agents, Alkylating Breast Neoplasms Carcinoma, Ehrlich Tumor Mice, Transgenic Naphthacenes Enzyme Inhibitors Lymphocyte Activation Cell Cycle Paclitaxel Topoisomerase I Inhibitors Cell Growth Processes Pyrroles Quinazolines Mice, Inbred C3H Blotting, Western Tumor Escape Mice, Knockout Intercalating Agents Zinostatin

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