• Anaplastic carcinoma Refers to a heterogeneous group of high-grade carcinomas that feature cells lacking distinct histological or cytological evidence of any of the more specifically differentiated neoplasms. (wikipedia.org)
  • These tumors are referred to as anaplastic or undifferentiated carcinomas. (wikipedia.org)
  • About 90% of cervical cancer cases are squamous cell carcinomas, 10% are adenocarcinoma, and a small number are other types. (wikipedia.org)
  • Endocervical adenocarcinoma (EAC) accounts for 20-25% of all cervical carcinomas ( 7 ). (iiarjournals.org)
  • Germ cell tumor with somatic-type solid malignancy is a germ cell tumor accompanied by a non-germ cell, the somatic-type malignant component in the form of sarcomas or carcinomas. (ejournals.ca)
  • 13 Synovial sarcomas often display morphologic features that overlap with a variety of other spindle cell sarcomas and carcinomas such as malignant peripheral nerve sheath tumor, leiomyosarcoma, solitary fibrous tumor, Ewing sarcoma/primitive neuroectodermal tumor, fibrosarcoma, sarcomatoid carcinoma, Müllerian adenosarcoma, and sarcomatoid mesothelioma. (ochsnerjournal.org)
  • Patients with SCA, specially with this pseudo solid-appearance, such as the present case, may have imaging findings that closely resemble those of patients with pancreatic neuroendocrine neoplasms (pNENs), metastatic renal cell carcinoma, solid pseudopapillary tumor or acinar cell carcinomas (1,4). (spg.pt)
  • Metaplastic carcinomas and phyllodes tumors were excluded. (oap-bioscience.org)
  • However, the vast majority of malignant ovarian tumors (80%-85%) are classified as epithelial tumors (carcinomas). (biomedcentral.com)
  • In contrast, 80%-90% of ovarian carcinomas are detected after the age of 40, and 40% of these tumors are detected after the age of 65. (biomedcentral.com)
  • Adenosquamous carcinoma Refers to a mixed tumor containing both adenocarcinoma and squamous cell carcinoma, wherein each of these cell types comprise at least 10% of the tumor volume. (wikipedia.org)
  • There are a large number of rare subtypes of anaplastic, undifferentiated carcinoma. (wikipedia.org)
  • Pleomorphic carcinoma contains spindle cell and/or giant cell components, plus at least a 10% component of cells characteristic of more highly differentiated types (i.e. adenocarcinoma and/or squamous cell carcinoma). (wikipedia.org)
  • Very rarely, tumors may contain individual components resembling both carcinoma and true sarcoma, including carcinosarcoma and pulmonary blastoma. (wikipedia.org)
  • Approximately 90% of these neoplasms are squamous cell carcinoma (SCC), with the remainder being adenocarcinoma, melanoma , and other rare histologic variants. (medscape.com)
  • revealed for the first time carcinoma ex microcystic adenoma in which the tumor, without metastases, showed inherent malignant changes [ 7 ]. (hindawi.com)
  • Objective: Laryngeal verrucous carcinoma (LVC) comprises 1% to 4% of all laryngeal tumors. (researchgate.net)
  • [ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)
  • Despite the declining incidence of cervical carcinoma, the proportion of adenocarcinomas arising from the uterine cervix has risen steadily ( 8 , 9 ). (iiarjournals.org)
  • Approximately 80-90% of newly diagnosed lung cancers are classified as NSCLC, primarily consisting of adenocarcinoma, squamous cell carcinoma, or large cell carcinoma histologies. (frontiersin.org)
  • Clear cell type renal cell carcinoma is a malignant tumor that can metastasize to many locations, but unusually spreads to thyroid. (scirp.org)
  • Clear cell renal carcinoma (CCRC) is a tumor with great metastatic capacity, although the presence of metastases in the thyroid gland is very uncommon. (scirp.org)
  • We report here a rare case of gastric carcinoma with multiple intramuscular metastases. (springeropen.com)
  • Reported cases of skeletal muscle metastases from gastric carcinoma are extremely rare. (springeropen.com)
  • Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • However, clinical and radiologic features of the tumor are not well known due to the rarity of the disease, which makes accurate diagnosis difficult. (bvsalud.org)
  • Pathological examination of an open muscle biopsy showed a poorly differentiated adenocarcinoma, supporting a diagnosis of gastric cancer metastases in multiple skeletal muscles. (springeropen.com)
  • The tumor was completely resected, the pathological diagnosis being adenocarcinoma, and small clump of cancer cells having been found in the muscularis propria (pathological stage T2N0M0 (AJCC classification), pathological effect grade 2) (Fig. 2 ). (springeropen.com)
  • Plasma circulating tumor DNA (ctDNA) sequencing has demonstrated clinical utility for tumor molecular profiling at initial diagnosis or tumor progression in advanced solid cancers and is being rapidly incorporated into. (koreamed.org)
  • Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
  • Lymph node inclusions of different types, including nevoid, squamous, and glandular, are rare but have been reported in multiple different anatomic locations including the axilla. (hindawi.com)
  • Pancreatic neuroendocrine tumors may be functional or nonfunctional. (medscape.com)
  • Overall, the age-adjusted incidence of neuroendocrine tumors increased sixfold from 1973 (1.09 per 100,000) to 2012 ((6.98 per 100,000), possibly because of increased early detection. (medscape.com)
  • No universally agreed-upon algorithm exists in the radiologic investigation of pancratic neuroendocrine (islet cell) tumors of the pancreas. (medscape.com)
  • There has been substantial evolution of concepts in neuroendocrine lung tumour classification. (ersjournals.com)
  • Synovial sarcoma, a malignant mesenchymal tumor, commonly involves the extremities and is rarely found in the pelvis. (ochsnerjournal.org)
  • Microscopic examination of the pelvic mass showed a biphasic tumor composed of epithelial and mesenchymal components, suggestive of synovial sarcoma. (ochsnerjournal.org)
  • A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. (curehunter.com)
  • The tumor is composed of two cellular components: Epithelial and mesenchymal. (cytojournal.com)
  • Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract. (medscape.com)
  • Primary breast sarcoma (PBS) is a malignant tumor arising from the mesenchymal tissue of the mammary gland. (oap-bioscience.org)
  • Tumors of the pancreas that contain substantial cystic components include mainly mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, solid pseudopapillary tumor, and cystadenomas (which encompass microcystic, macrocystic/oligocystic, and rare solid serous adenomas). (hindawi.com)
  • Serous cystadenoma (SCA) is a relatively rare pancreatic neoplasm which accounts for only 2% of pancreatic tumors (1-3). (spg.pt)
  • Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive lymphoma with an overall incidence of 0.04 cases per 100,000 people. (koreamed.org)
  • SPPT) is a rare exocrine pancreatic neoplasm, tumor' of the pancreas.4 not conflict of interests. (bvsalud.org)
  • Malignant transformation in the tumor with metastases is rare and only about 26 cases have been reported so far. (hindawi.com)
  • Renal metastases are usually discovered during evaluation of the primary tumor or incidentally during abdominal imaging. (msdmanuals.com)
  • Lesions based on histology were classified as cortical adrenal hyperplasia ( n = 67), adenocarcinoma ( n = 17), pheochromocytoma ( n = 10), metastases ( n = 7), adrenal adenoma ( n = 4), and adrenalitis ( n = 4). (biomedcentral.com)
  • Cavernous sinus metastases are rare, and the cavernous sinus syndrome is rarely the first sign of cancer, especially in young patients. (surgicalneurologyint.com)
  • These tumors are often located in the anterior mediastinum and occur in adult males with a peak incidence between 20-40 years. (ejournals.ca)
  • Incidence rates and tumour localisation vary considerably between geographical regions thus implying genetic and environmental factors in disease pathophysiology. (docksci.com)
  • The microbiome may lack statistical power to detect common, tumour site concordances can also play a critical part in host an increase in tumour incidence at among the species studied. (who.int)
  • Pancreatic cystic tumors fall into the serous or mucinous category. (hindawi.com)
  • Malignant transformation of cystic adenomas of the pancreas was first described in 1989 wherein the tumor showed invasion into surrounding structures and into the liver [ 4 ]. (hindawi.com)
  • The tumor may present as a heterogeneous solid or cystic mass accompanied by calcifications. (bvsalud.org)
  • Lin C, Du Y, Li Y, Wang H, Chang J. Superior mediastinal mature cystic teratoma with gastrointestinal adenocarcinoma transformation: Report of a case. (ejournals.ca)
  • Sakurai H, Miyashita Y, Oyama T. Adenocarcinoma arising in anterior mediastninal mature cystic teratoma: Report of a case. (ejournals.ca)
  • Adenocarcinoma with sarcomatous dedifferentiation arising from mature cystic teratoma of the anterior mediastinum. (ejournals.ca)
  • Muramatsu T, Nishii T, Ohmori K, Shiono M. Mature cystic teratoma with malignant transformation to adenocarcinoma. (ejournals.ca)
  • It presented heterogeneous echogenicity, with cystic areas and nodular images. (scirp.org)
  • Contrast-enhanced computed tomography of the abdomen suggested a well-circumscribed, heterogeneous, solid-cystic mass in the left adnexal region measuring 13.9 × 10 × 9.1 cm and compressing the adjacent structures. (ochsnerjournal.org)
  • In rare cases, however, the cysts are so small and crammed together that it presents as a pseudo solid-appearing serous cystic adenoma (1). (spg.pt)
  • [ 1 ] Fine-needle aspiration is the main diagnostic procedure in the workup of occult primary tumors of the head and neck, with panendoscopy being the primary surgical therapy used to discover an occult primary lesion. (medscape.com)
  • Cancers with no known primary lesion site represent a heterogeneous group of malignancies that have been estimated to account for 0.5-10% of all tumors. (medscape.com)
  • In August 2015 a right renal tumor and a sternal lithic lesion were found in control CT without signs of rectal relapse. (scirp.org)
  • Analysis of ultrasonographic predictive parameters showed a significant association between lesion size and malignant tumors. (biomedcentral.com)
  • The authors present the case of a 83-year-old man with a computed tomography (CT) scan done for other purposes showing the presence of a hyperenhancing, discretely heterogeneous nodular lesion in the neck of the pancreas, with slightly irregular margins, measuring 30x20mm. (spg.pt)
  • World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002). (curehunter.com)
  • In addition, rare pathology not previously documented in the adrenal gland will be described. (bmj.com)
  • Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. (biomedcentral.com)
  • These germ cell tumors are rare, accounting for only about 2% of all germ cell tumors in men. (ejournals.ca)
  • The currently accepted nomenclature is solitary fibrous tumor. (medscape.com)
  • Pathologists should carefully evaluate lymph node inclusions to ensure that intrinsic malignancies are not missed within rare otherwise benign appearing incidental epithelial rests. (hindawi.com)
  • Background: Wilms tumor (WT) is one of the most common malignancies in childhood. (uni-wuerzburg.de)
  • Although primary pelvic synovial sarcoma is a rare occurrence, this case illustrates that synovial sarcoma can be diagnosed or at least suspected on FNAC. (ochsnerjournal.org)
  • Intraoperatively, a large cervical tumor was observed with greater size of the right lobe, measuring approximately 12 × 10 cm and moving the trachea to the left. (scirp.org)
  • These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. (biomedcentral.com)
  • According to the 2014 World Health Organization (WHO) classification and tumor morphology, primary ovarian tumors are subdivided into three categories: epithelial (60%), germ cell (30%), and sex-cord stromal tumors (8%)[ 1 ]. (biomedcentral.com)
  • Malignant germ cell and sex-cord stromal tumors comprise approximately 10% of all malignant ovarian tumors. (biomedcentral.com)
  • Evidence has shown that endoscopic ultrasonography (EUS) can be used to accurately diagnose and localize primary endocrine tumors of the pancreas, especially insulinomas and gastrinomas. (medscape.com)
  • Colorectal cancers are one of the most prevalent tumour types worldwide and, despite the emergence of targeted and biologic therapies, have among the highest mortality rates. (researchgate.net)
  • They represent 30% of all epithelial tumors and 80%-85% of all ovarian cancers. (biomedcentral.com)
  • Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
  • These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
  • Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)
  • To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
  • 1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)
  • Adrenal gland lesions (nodules and masses) commonly develop in older dogs, but surgery is indicated in only a small fraction of such cases, usually in malignant and hormone-secreting tumors [ 13 ]. (biomedcentral.com)
  • While ultrasonography is an effective method for localizing adrenal lesions, standardized ultrasound criteria to distinguish benign from malignant lesions or functional cortisol-secreting from non-functional tumors are lacking [ 12 ]. (biomedcentral.com)
  • Results Sixty-two patients underwent biliary stenting alone, 5 patients underwent both biliary and pancreatic stenting, and 237 patients were not stented in the adenocarcinoma group without chronic pancreatitis. (thieme-connect.de)
  • MRI has a role in these patients in determining tumor extent and suitable therapy. (radiopaedia.org)
  • Approximately 75%-80% of ovarian tumors are benign, occurring in patients under 40 years of age. (biomedcentral.com)
  • These tumors are primarily found in elderly patients with a median age of 60 years. (biomedcentral.com)
  • Data from whole transcriptome sequencing of 33 breast specimens in the Harbin Medical University Cancer Center cohort and The Cancer Genome Atlas was applied to identify and validate the landscape of tumor suppressor long noncoding RNAs, which was further validated by The Cancer Genome Atlas pancancer data including 33 cancer types and 12,839 patients. (cancerindex.org)
  • We stained a tissue microarray consisting of 170 patients, including 72 intrahepatic cholangiocarcinomas (iCCAs), 57 perihilar cholangiocarcinomas (pCCAs) and 41 distal cholangiocarcinomas (dCCAs) by immunohistochemistry and evaluated PD-L1 positivity in tumor and stromal cells. (biomedcentral.com)
  • Statistical analyses of PD-L1 expression (clone SP263) on tumor cells with clinicopathological data revealed a positive correlation with shortened overall survival in CCA patients. (biomedcentral.com)
  • MRI showed that anterior mediastinal mass showed intermediate signal intensity on T1-weighted images (T1WI), high SI on T2-weighted images (T2WI), and heterogeneous enhancement. (bvsalud.org)
  • Biopsy was performed and the anterior mediastinal tumor was diagnosed as thymic mucinous adenocarcinoma by histopathologic examination and immunohistochemical staining. (bvsalud.org)
  • CONCLUSION: Thymic mucinous adenocarcinomas could be included in differential diagnoses of anterior mediastinal tumors showing extensive calcification, and common imaging findings of mucinous adenocarcinoma such as T2 high signal intensity and heterogeneous enhancement on MRI may be helpful to diagnose thymic mucinous adenocarcinoma. (bvsalud.org)
  • Data were gathered from a PubMed search of peer-reviewed literature on mediastinal tumors. (allenpress.com)
  • Mediastinal teratoma with coexisting adenovarcinoma and carcinoid tumour (somatic-type malignancy): A case report with a review of the literature. (ejournals.ca)
  • Fevre CL, Vigneron C, Schuster H, Walter A, Marcellin L, Massard G, Lutz P, Noel G. Metastatic mediastinal mature teratoma with malignant transformation in young man with an adenocarcinoma in Klinefelter's syndrome: Case report and review of the literature. (ejournals.ca)
  • Mediastinal and retroperitoneal teratoma with focal gastrointestinal adenocarcinoma. (ejournals.ca)
  • Murakami K, Hamaji M, Yoshizawa A, Date H. Sub-centimeter adenocarcinoma arising from mature mediastinal teratoma during 11 years of follow‑up. (ejournals.ca)
  • Background/Aim: Gastric-type endocervical adenocarcinoma (GEA) is a rare but distinct histological type of gynecological malignancy. (iiarjournals.org)
  • One hundred years ago, lung cancer was a rare malignancy ( 1 ). (frontiersin.org)
  • Based on the clinical finding, radiologic, and routine histopathological examination, this case was concluded as mature teratoma with somatic-type solid malignancy in the form of mucinous adenocarcinoma. (ejournals.ca)
  • There are several variants of cutaneous melanocytic tumors, characterized by differing clinical and pathologic features. (atlasgeneticsoncology.org)
  • In each case, the clinical presentation, location of the tumour, and the outcome for the patient were studied. (bmj.com)
  • Although nonfunctional islet cell tumors are not uncommon at autopsy, most islet cell tumors with clinical manifestations are functional. (medscape.com)
  • Functioning tumors produce a clinical syndrome as a result of excessive hormone production. (medscape.com)
  • Clinical features of the syndrome depend on tumor cell type. (medscape.com)
  • In their review " Natural and Adaptive Immunity to Cancer ", Vesely and colleagues draw from recent mouse models of cancer and human clinical data to describe how cells, effector molecules, and pathways of the immune system act to suppress and control tumor cells. (massgenomics.org)
  • Results: The association of retinoid signaling and clinical parameters could be validated in a large independent tumor set, but its relevance in primary nephrectomy tumors from very young children may be different. (uni-wuerzburg.de)
  • The therapeutic decision considers clinical and functional status, the extent of primary and metastatic disease, radiological study, tumor histopathology, and biological behavior. (surgicalneurologyint.com)
  • EAC comprises a heterogeneous group of tumors of varying etiology and morphology ( 10 - 12 ). (iiarjournals.org)
  • Congenital microcephaly comprises a heterogeneous group of disorders in which brain volume is reduced, in the absence or presence of variable syndromic features. (cancerindex.org)
  • Epithelial ovarian cancer comprises a heterogeneous group of tumors. (nih.gov)
  • We describe two cases of rectal herpes simplex virus (HSV) infection in men that clinically mimicked rectal adenocarcinoma. (hindawi.com)
  • The distinction among these various tumors is important both clinically and epidemiologically. (medscape.com)
  • Background CD30+ T-cell lymphoproliferations comprise a spectrum of clinically heterogeneous entities, including systemic anaplastic large cell lymphomas (ALK- and ALK+) and primary cutaneous CD30+ T-cell lymphoproliferative disorders. (uni-wuerzburg.de)
  • 1 Fine needle aspiration cytology (FNAC) is a well-accepted, minimally invasive procedure and an effective method of diagnosing benign and malignant soft tissue tumors of the extremities and deep body cavities. (ochsnerjournal.org)
  • Nonfunctioning tumors usually are larger and present because of their size or metastatic spread. (medscape.com)
  • Overview of Lymphoma Lymphomas are a heterogeneous group of tumors arising in the reticuloendothelial and lymphatic systems. (msdmanuals.com)
  • Spitz tumors include a group of cutaneous melanocytic tumors that share certain histologic features. (atlasgeneticsoncology.org)
  • Islet cell tumors in this group are often multiple and malignant. (medscape.com)
  • Adenocarcinomas of the distal stomach are dominant in Eastern Europe, Asia and South America. (docksci.com)
  • Since the 2014 World Health Organization (WHO) Classification of Tumors of Female Reproductive Organs ( 13 ) did not fully reflect the current understanding of diverse mechanisms underlying endocervical glandular carcinogenesis, a novel classification system was proposed to provide an updated framework for EAC classification. (iiarjournals.org)
  • The International Endocervical Adenocarcinoma Criteria and Classification (IECC) reliably segregated EACs into human papillomavirus (HPV)-related and HPV-unrelated tumors according to the presence or absence of HPV infection-related morphology (apical mitotic figures and basal apoptotic bodies), which is easily identifiable under scanning magnification ( 12 ). (iiarjournals.org)
  • With the adoption of the 2018 IECC, the updated 2020 WHO Classification of Female Genital Tumors ( 14 ) designated these tumors as HPV-associated (HPVA) and HPV-independent (HPVI) EACs. (iiarjournals.org)
  • Stage III lung cancer, though heterogeneous in its classification, includes non-metastatic but locally advanced disease with involvement of N1-N3 nodal stations and/or T3 and T4 primaries. (frontiersin.org)
  • An international system of tumour classification is important for consistency in patient treatments and to provide the basis of epidemiological and biological studies. (ersjournals.com)
  • For several tumour sites (i.e. lung, concordance, and in the degree to tions of tumour site concordance. (who.int)
  • Genital warts, which are a form of benign tumor of epithelial cells, are also caused by various strains of HPV. (wikipedia.org)
  • The tumor also contains neoplastic epithelial cells that form a solid, cribriform, acinic and papillary structure in the extracellular mucinous pool. (ejournals.ca)
  • Shown here is a gastric gastrointestinal stromal tumor (GIST). (medscape.com)
  • She underwent ultrasound-guided FNAC of the abdominal mass, and it was diagnosed as adenocarcinoma of the ovary. (ochsnerjournal.org)
  • A 26-year-old woman who presented with pain in the epigastrium and left hypochondrium, with Tumor pseudopapilar increased abdominal perimeter and loss of 5 kg of body weight. (bvsalud.org)
  • Se trata de una mujer de 26 años que presentó dolor en epigastrio e hipocondrio izquierdo, con aumento del perímetro abdominal y pérdida de 5 kg de peso corporal. (bvsalud.org)
  • Fine-needle aspiration is the main diagnostic procedure in the workup of occult primary tumors of the head and neck. (medscape.com)
  • [ 12 ] Rare cases of primary pulmonary or pleural DSRCT have subsequently been identified. (medscape.com)
  • Multiple studies have examined the issue of the optimal dose of radiotherapy in NSCLC but are complicated by the heterogeneity of the disease itself in terms of size and location of the primary tumor, number and size of involved lymph nodes, and the patient's comorbidities, all of which limit the treatment tolerability and risks. (frontiersin.org)
  • Delivery of tumoricidal doses to the primary tumor and involved lymph nodes is balanced by treatment-related toxicities, namely esophagitis, pneumonitis, and cardiac injury. (frontiersin.org)
  • Treatment is systemic therapy for the primary tumor and, rarely, surgery. (msdmanuals.com)
  • Based on pathological report demonstrating that the primary tumor was HER2-positive, the patient was commenced on chemotherapy with trastuzumab. (springeropen.com)
  • To search for possible modes of action of retinoids as novel therapeutic options, primary tumor cell cultures were treated in vitro with all-trans-RA (ATRA), 9cis-RA, fenretinide and combinations of retinoids and a histone deacetylase (HDAC) inhibitor. (uni-wuerzburg.de)
  • In vitro testing of primary tumor cultures provided clear evidence of a potential utility of retinoids in Wilms tumor treatment based on the analysis of gene expression, proliferation, differentiation and apoptosis. (uni-wuerzburg.de)
  • Immunohistochemistry suggested adenocarcinoma and possible breast or primary gynecologic tumor. (surgicalneurologyint.com)
  • Next, the expression model, prognostic roles, potential biological functions and epigenetic regulation of tumor suppressor long noncoding RNAs were investigated and validated in the breast cancer and pancancer cohorts. (cancerindex.org)
  • Histopathological examination of the tumor mass revealed an admixture of spindle cells and epithelioid cells. (cytojournal.com)
  • Despite extensive interstitial involvement, symptoms are rare, and renal function may not change from baseline. (msdmanuals.com)
  • Ovarian epithelial tumors are subclassified into several categories based on two criteria: 1) the degree of epithelial proliferation and invasion and 2) the histotype of the epithelium composing the tumor. (biomedcentral.com)
  • There was no significant correlation between COX-2 expression and age, gender, tumour location, tumour size, depth of invasion or lymph node status.However, COX-2 expression revealed a significant correlation with tumour grade (p= 0.013). (bvsalud.org)
  • Conclusions: Altered retinoic acid signaling has been validated especially in high risk Wilms tumors. (uni-wuerzburg.de)
  • Gene ID: 5925, OMIM 614041 ) gene, which encodes a tumor suppressor protein. (molvis.org)
  • Landscape of tumor suppressor long noncoding RNAs in breast cancer. (cancerindex.org)
  • The landscape and biological functions of tumor suppressor long noncoding RNAs in breast cancer are still unknown. (cancerindex.org)
  • Mechanistically, EPB41L4A-AS2, acting at least in part as a tumor suppressor, upregulated tumor suppressor gene expression. (cancerindex.org)
  • 4A) Junctional tumor composed of numerous junctional nests of pigmented melanocytes. (atlasgeneticsoncology.org)
  • Pagetoid suprabasilar spread of single melanocytes and nests of melanocytes is present in this image from the center of the tumor. (atlasgeneticsoncology.org)
  • The biopsy showed nests of infiltrating tumor cells with frequent atypical mitoses, hyperchromasia, occasionally prominent nucleoli, scant eosinophilic cytoplasm and no distinct cell borders. (pathologyoutlines.com)
  • mucinous and Brenner malignant tumors potentially develop from the Walthard nests. (biomedcentral.com)
  • However, in vitro screens are limited to a lack of tumor microenvironment, and the gRNA library coverage or selection often limits the pathological relevance of targets unraveled by in vivo screens. (nature.com)
  • Glioblastoma multiforme and medulloblastoma are the most frequent high-grade brain tumors in adults and children, respectively. (cancerindex.org)
  • Although the latter is a relatively rare entity, it often presents diagnostic or therapeutic challenges owing to the distinct histological and molecular characteristics and different response to standard therapies ( 16 ). (iiarjournals.org)
  • Her research has redefined the molecular map of breast cancer and led to new paradigms in understanding how human tumors evolve and metastasize. (stanford.edu)
  • There are several stage, lifestyle, sex, and the impact late-developing tumours, or studies other tumour sites with fewer, or less of co-exposures. (who.int)
  • There are various limitations in susceptibility, how host susceptibility ies may focus only on specific tumour epidemiological studies (e.g. statis- factors may modulate the impact of outcomes or may not be designed to tical power, exposure assessment, mechanistic events leading to tumour detect some types of tumours). (who.int)