• The standard of care for patients with newly diagnosed GBM comprises maximum safe resection of the tumor followed by radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy [ 3 , 4 ]. (springer.com)
  • Methods: Review of records of 541 women treated within the North London Gynaecological Cancer Network between 2003 and 2010 with radiotherapy with or without chemotherapy for cervical and endometrial cancer identified 152 women who reported significant new bowel symptoms after pelvic radiation. (ucl.ac.uk)
  • It may be seen in greater than 90% of patients older than 60 years who have been successfully treated with combination chemotherapy and whole-brain radiation. (medscape.com)
  • Patients with multifocal high-grade glioma treated with conventionally fractionated radiation therapy (RT) in our institution with or without concomitant chemotherapy between April 2011 and April 2019 were retrospectively analysed. (biomedcentral.com)
  • The current standard of care for locally advanced non-small cell lung cancer (NSCLC) includes radiation, chemotherapy, and surgery in certain individualized cases. (frontiersin.org)
  • However, for patients with more locally advanced NSCLC, 5-year OS after treatment with definitive radiation therapy and concurrent chemotherapy remains modest, at approximately 15-20% ( 4 ). (frontiersin.org)
  • Prior to the advent of cytotoxic chemotherapy, lung cancer at all stages was treated surgically or by radiation alone ( 5 , 6 ). (frontiersin.org)
  • Presently, stage III lung cancer is managed with a combination of chemotherapy, radiation therapy, and sometimes surgery but the two major challenges in improving outcomes of the treatment of this disease remain local control and metastatic spread. (frontiersin.org)
  • What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (cnr.it)
  • Further studies that account for chemotherapy and examine frequency and duration of radiotherapy would be of interest in confirming the observed association. (nih.gov)
  • The book is divided into two parts: the first covers underlying principles of physics, and the second is a systematic review by tumour site concentrating on the role of radiotherapy in the treatment of malignant disease and setting its use in context with chemotherapy and surgery. (scopewe.com)
  • A team of medical researchers in Italy have achieved what they are calling "excellent" tumor control and survival results in malignant pleural mesothelioma patients using a combination of surgery, chemotherapy, and radiotherapy. (survivingmesothelioma.com)
  • As one of the four major means of cancer treatment including surgery, radiotherapy (RT), chemotherapy, immunotherapy, RT can be applied to various cancers as both a radical cancer treatment and an adjuvant treatment before or after surgery. (nature.com)
  • In order to carry out this study, a convenience sample was employed consisting of 32 patients subjected to radiotherapy treatment in the area of the head and neck, both with and without associated chemotherapy and surgery, between the months of January and June 2012. (bvsalud.org)
  • In order to achieve a more effec- were recommended postoperative radiation and adjuvant tive and individualised chemotherapeutic treatment of breast chemotherapy. (lu.se)
  • Evaluation of the long-term outcomes from an open-label randomised controlled trial (TARGIT-A) published in 2020, demonstrated that TARGIT-IORT is as effective as whole breast external beam radiotherapy in controlling cancer for patients with breast cancer. (wikipedia.org)
  • Conventional radiation techniques such as external beam radiotherapy (EBRT) following surgical removal of the tumour have been time tested and proven to be effective. (wikipedia.org)
  • In order to instantly stabilize and sterilize the affected vertebral bodies, combined kyphoplasty and intraoperative radiotherapy (Kypho-IORT) provides a promising local treatment option as alternative to the external beam radiotherapy (EBRT) as standard-of-care. (zeiss.com)
  • Images show initial anteroposterior (AP, left) and lateral (right) fields used for postoperative adjuvant pelvic external-beam radiotherapy in a patient with stage IC grade 2 adenocarcinoma of the endometrium who underwent hysterectomy. (medscape.com)
  • Hypofractionated radiotherapy is the current standard for adjuvant radiotherapy across many centres. (authorea.com)
  • Patients without distant metastases who merit adjuvant radiotherapy will be eligible for inclusion in the study. (authorea.com)
  • Patients in the control arm will receive adjuvant radiotherapy to the breast or chest wall (with/without regional nodes) to a dose of 40 Gy / 15 fractions / 3 weeks, while those in the experimental arm will receive a dose of 26 Gy / 5 fractions / 1 week (to the same volume). (authorea.com)
  • Adjuvant radiotherapy is necessary if breast cancer is treated by removing only the cancerous lump with a rim of surrounding normal tissue, as it reduces the chance of local recurrence. (wikipedia.org)
  • Adjuvant radiotherapy in advanced head and neck squamous cell cancer (HNSCC) reduces the risk of local-regional failure and most likely increases the survival rate. (biomedcentral.com)
  • In the six trials of interest, a total of 988 patients with locally advanced HNSCC were randomly assigned to receive either accelerated or conventionally fractionated adjuvant radiotherapy. (biomedcentral.com)
  • Adjuvant radiotherapy with a total dose of 50 Gy was performed for each participant. (ac.ir)
  • Although adjuvant radiotherapy is commonly used to manage advanced or metastatic cervical and endometrial cancer, it is sometimes administered as adjuvant therapy for ovarian cancer. (medscape.com)
  • In most instances, traditional external beam radiation therapy (EBRT) is generated by a photon unit or a Cobalt-60 unit. (medscape.com)
  • As a side note, meningiomas and acoustic neuromas were not treated with traditional radiation therapy because they were thought to be radiation resistant and because of their proximity to vital neurovascular structures and contact with the brain stem. (medscape.com)
  • Radiation therapy is a highly complex cancer treatment that requires multiple specialists to create a treatment plan and provide quality assurance (QA) prior to delivery to a patient. (jove.com)
  • The Radiation Planning Assistant (RPA) is a system developed for the fully automated creation of radiotherapy treatment plans, including volume-modulated arc therapy (VMAT) plans for patients with head/neck cancer and 4-field box plans for patients with cervical cancer. (jove.com)
  • In other countries, the radiation therapy technologists (often called radiographers) also take on a treatment planning role. (jove.com)
  • Low- and middle-income countries (LMICs) have serious deficits in radiation oncologists, medical physicists and radiation therapy technologists. (jove.com)
  • In today's world of advancing technology, three-dimensional conformal radiation therapy (3D-CRT)planning systems are able to generate treatment schemes that are supposedly conformal to the tumor/target volume thereby limitingthe dose that reaches the surrounding normal tissues. (oncolink.org)
  • This clinically proven system for high-precision cancer treatment offers local and regional patients access to next-generation radiation therapy treatment. (brainlab.com)
  • Future plans in Radiation Oncology at Alfred Health include Brainlab HybridArc™ techniques and Adaptive Radiation Therapy. (brainlab.com)
  • Core products revolve around less-invasive image guided surgery technology, more accurate and effective radiation therapy, and integration through planning and collaboration systems that brings patient data and physicians together. (brainlab.com)
  • HYPOfractionated Radiation Therapy comparing a standard radiotherapy schedule (over three weeks) with a novel one week schedule in Adjuvant breast cancer: An open-label randomised controlled study (HYPORT- Adjuvant): study protocol for a multicenter, randomized phase III trial. (authorea.com)
  • It is a pain-free treatment and external radiation therapy does not make you radioactive. (calcuttayellowpages.com)
  • In the clinical situation of a recurrent astrocytoma (postradiation therapy), radiation necrosis presents a diagnostic dilemma. (medscape.com)
  • A relationship between increased blood-brain barrier permeability and radiation therapy has been posited to contribute to this leukoencephalopathy and to methotrexate-induced vasculopathy. (medscape.com)
  • They note that although radiation therapy can provide some palliation in such patients, it can also result in radiation necrosis and neurologic decline. (medscape.com)
  • Targeted intra-operative radiotherapy, also known as targeted IORT, is a technique of giving radiotherapy to the tissues surrounding a cancer after its surgical removal, a form of intraoperative radiation therapy. (wikipedia.org)
  • is a cooperation project of the Department of Radiation Oncology and Radiation Therapy under the direction of Prof. Dr. Zips and the Department of Neurosurgery under the direction of Prof. Dr. med. (charite.de)
  • The treatment often includes some type of surgical procedure or radiation therapy. (mydr.com.au)
  • Early-stage, localized disease may be treated with radiation therapy or excision in certain cases. (medscape.com)
  • In clinical practice accelerated postoperative radiation therapy might be a suitable option only for a subset of patients. (biomedcentral.com)
  • Surgery, radiation therapy (RT), or both have been used for decades to improve loco-regional control (LRC) and overall survival (OS). (biomedcentral.com)
  • Overall and progression-free survival were calculated from the diagnosis until death and from start of radiation therapy until diagnosis of progression of disease in MRI for all patients. (biomedcentral.com)
  • Resection was performed in two cases and stereotactic biopsy only in 18 cases before the start of radiation therapy. (biomedcentral.com)
  • At the start of radiation therapy patients were 61 years old in median (range 42-84 years). (biomedcentral.com)
  • Radiotherapy should not be confused with radioiodine therapy, which is used to treat hyperthyroidism and sometimes thyroid tumours in cats. (vethelpdirect.com)
  • Aggressive tumors typically demonstrate a high glycolytic rate, which results in resistance to radiation therapy and cancer progression via several molecular and physiologic mechanisms. (springer.com)
  • We conclude that CR and KDs may act synergistically with radiation therapy for the treatment of cancer patients and provide some guidelines for implementing these dietary interventions into clinical practice. (springer.com)
  • Despite these advancements, several cancer types continue to elude modern treatment techniques with radiation therapy (RT). (springer.com)
  • A multidisciplinary team composed of radiation oncologists, nurses, radiation therapists, and medical physicists will discuss radiation therapy as a treatment option, assess users, plan and deliver users' treatments, and assist users with any side effects experienced. (researchandmarkets.com)
  • Radiation therapy, often known as radiation, has acquired recognition as a highly effective cancer treatment option for reducing cancer-related morbidity and mortality. (researchandmarkets.com)
  • Treatment approaches include stereotactic radiosurgery, volumetric-modulated arc therapy, 3D high-dose-rate brachytherapy, and 3D conformal radiation have all grown in popularity. (researchandmarkets.com)
  • Over the last 17 years, stereotactic body radiation therapy (SBRT) has shown a high degree of safety and local control for stage I lung cancers and other localized malignancies. (frontiersin.org)
  • An early dose-finding study by the Radiation Therapy Oncology Group (RTOG) 7301 study was conducted from 1973 to 1978 and studied four different doses and schedules: 40 Gy split course, 40 Gy continuously, 50 Gy, and 60 Gy. (frontiersin.org)
  • Radiation therapy is a key component of care for many types of cancers. (arthealth.com)
  • It is the first time the new approach, known as biology-guided radiation therapy or SCINTIX TM , has been used in a clinic. (arthealth.com)
  • Since March 2017, clinicians in the Department of Oncology and Radiation Therapy at Turku University Hospital (Turku, Finland) have been using Philips MR-only simulation for simulating and planning radiation therapy for their patients with prostate cancer. (philips.com)
  • The radiation therapy department at Turku University Hospital (TYKS) has been home to a Philips Ingenia MR-RT 1.5T since January 2016. (philips.com)
  • People who have received radiation therapy for other types of cancer could be at an increased risk for developing GCTs. (medicinenet.com)
  • CHICAGO -- The use of androgen deprivation therapy (ADT) in conjunction with radiotherapy, as well as its prolonged use in the adjuvant setting, improved metastasis-free survival (MFS) and overall survival (OS) in patients with localized prostate cancer, a meta-analysis found. (medpagetoday.com)
  • Daniel Hamstra, MD, PhD, of Baylor College of Medicine in Houston, told MedPage Today that the study reaffirms what radiation oncologists knew about hormonal therapy and radiation therapy in men with high-risk prostate cancer. (medpagetoday.com)
  • The analysis included 10,853 patients from 12 radiotherapy trials, for whom the researchers analyzed outcomes related to three aspects of ADT: the addition of ADT to radiation therapy (median follow-up 12 years), and the prolongation of adjuvant ADT (median 10.9 years follow-up), and neoadjuvant ADT (median 10.3 years follow-up). (medpagetoday.com)
  • Of these 12 trials, six evaluated ADT use (in more than 5,000 patients), mostly the addition of 3 to 6 months of ADT to radiation therapy. (medpagetoday.com)
  • Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol. (upenn.edu)
  • Local control dependence on consecutive vs. nonconsecutive fractionation in lung stereotactic body radiation therapy. (upenn.edu)
  • Efficacy and safety of stereotactic body radiation therapy for the treatment of pulmonary metastases from sarcoma: A potential alternative to resection. (upenn.edu)
  • Radiation therapy is a common treatment for mesothelioma patients that can be used for pain relief and tumor shrinking. (survivingmesothelioma.com)
  • Patients treated with radiation therapy after surgery showed promising results. (survivingmesothelioma.com)
  • Stereotactic body radiation therapy may be a safe treatment option for patients with malignant pleural mesothelioma. (survivingmesothelioma.com)
  • The value and safety of radiation therapy for mesothelioma patients are promising. (survivingmesothelioma.com)
  • The 7th edition continues the tradition of bringing the physics and clinical application of radiation for therapy together at entry level and is completely revised to take into account the huge technological advances in radiotherapy treatment since publication of the previous edition. (scopewe.com)
  • For radiation therapy to be effective, the radiation beams must be aimed precisely at the same area each and every time you have treatment. (materprivate.ie)
  • The NCCN Radiation Therapy Compendium™ includes information designed to support clinical decision-making around the use of radiation therapy in patients with cancer and is based directly on the NCCN Guidelines. (nccn.org)
  • The NCCN Radiation Therapy Compendium™ is accessible through a subscription-based searchable user interface and includes a full complement of radiation therapy recommendations found in the current Guidelines. (nccn.org)
  • The NCCN Radiation Therapy Compendium™ is reviewed on a continual basis to ensure that the recommendations take into account the most current evidence, and is recognized by public and is a reference for radiation oncology coverage policy. (nccn.org)
  • Over half of cancer patients undergo radiation therapy (RT). (nature.com)
  • Fractionated doses are often used in radiation therapy. (cdc.gov)
  • Over the sixty years of its existence, the IAEA/WHO postal dose audit service has played an important role in improving the accuracy and consistency of dosimetry in radiation therapy worldwide. (who.int)
  • As part of the FABREC study, Julia Wong, M.D., of the Dana-Farber Brigham Cancer Center in Boston, and colleagues found that patients with breast cancer who undergo implant-based reconstruction immediately following mastectomy and receive a shorter course of radiation therapy experience similar outcomes to patients who receive a conventional course of radiation. (msdmanuals.com)
  • The researchers found that patients receiving the short course and those receiving the conventional course of radiation therapy experienced comparable outcomes. (msdmanuals.com)
  • In this study, the authors enrolled patients who were unable or unwilling to undergo surgery and tested a novel therapy -- stereotactic ablative body radiotherapy (SABR) -- as a curative treatment option. (msdmanuals.com)
  • Radiation therapy is an essential component in Gynecology in the primary nonsurgical management and the adjuvant postoperative treatment of selected malignancies arising in the female reproductive tract. (medscape.com)
  • Radiation therapy may also be used for hormonal ablation. (medscape.com)
  • In this article, clinical indications and common techniques for radiation therapy in the management of common gynecologic cancers are described. (medscape.com)
  • Radiotherapy was delivered to ipsilateral axil- cancer patients in the future, it is essential to increase our lary and supraclavicular lymph nodes and the remaining knowledge in mechanisms responsible for drug resistance, breast parenchyma after breast conservation surgery or tho- and to define reliable indicators for response to therapy. (lu.se)
  • Furthermore, some tumors were said to be resistant to radiation, often because of dose limitations of the surrounding or adjacent tissues. (medscape.com)
  • Stereotactic radiotherapy is the term used to define the method of delivery of a precise dose of high-energy radiation through stereotactically directed narrow beams. (medscape.com)
  • Leksell formulated the term stereotactic radiosurgery for this method, and in the literature, stereotactic radiosurgery is the term used for single-dose stereotactic radiation treatment. (medscape.com)
  • It has been known that radiation could eradicate tumors -- the radiation treatments just needed to utilize a "high enough" dose. (oncolink.org)
  • This would, thus, allow the radiation oncologists to increase the doses to thetarget (the prostate, in this case), while minimizing dose to the normal tissues in proximity (bladder, intestine and rectum). (oncolink.org)
  • Our purpose was to develop a model comparing dose distributions of image-guided and adaptive radiotherapy (ART) techniques for canine bladder cancer. (avmi.net)
  • The rationale for TARGIT is to deliver a high dose of radiation precisely to the tumour bed. (wikipedia.org)
  • If necessary, the radiation dose can be divided into three to five treatment sessions. (charite.de)
  • Split-course radiotherapy (RT) was administered to a total dose of 40 Gy, with a 2-week treatment break. (cancernetwork.com)
  • By building on the proven concept of conventional chemoradiation for patients with locally advanced NSCLC with a subsequent radiation dose intensification to residual disease with SBRT concurrent with immunotherapy, we hope address the issues of metastatic and local failures. (frontiersin.org)
  • Multiple studies have examined the issue of the optimal dose of radiotherapy in NSCLC but are complicated by the heterogeneity of the disease itself in terms of size and location of the primary tumor, number and size of involved lymph nodes, and the patient's comorbidities, all of which limit the treatment tolerability and risks. (frontiersin.org)
  • Featuring the solution's MRCAT approach, physicists can obtain the needed electron density information for radiotherapy dose calculations, rendering CT unnecessary in the workflow. (philips.com)
  • His current interests are MRI in radiotherapy, small-field dosimetry and dose calculation, quality assurance, and stereotactic and adaptive treatments. (philips.com)
  • Brachytherapy is a cancer treatment using high radiation dose to the tumor, without irradiating the adjacent tissues. (brachycenter.com)
  • There was no significant interaction in the benefit of ADT use by radiotherapy dose or NCCN [National Comprehensive Cancer Network] risk group," he added. (medpagetoday.com)
  • Using 15-15 MV photon beam energies field can significantly reduce the absorbed dose to the thyroid gland and consequently can reduce the risk of developing hypothyroidism in breast cancer patients treated with radiotherapy. (ac.ir)
  • An interim analysis of an ongoing Phase III study from UCLA Jonsson Comprehensive Cancer Center indicates that using magnetic resonance imaging (MRI) to guide precisely-focused high-dose radiation treatment for prostate cancer reduced side effects associated with the treatment. (uclahealth.org)
  • Advanced radiation techniques like high-dose stereotactic body radiotherapy (SBRT) offer the opportunity to deliver high radiation doses to tumors while sparing surrounding tissues. (uclahealth.org)
  • Acute Radiation Syndrome (ARS) (sometimes known as radiation toxicity or radiation sickness) is an acute illness caused by irradiation of the entire body (or most of the body) by a high dose of penetrating radiation in a very short period of time (usually a matter of minutes). (cdc.gov)
  • · The dose usually must be external (i.e., the source of radiation is outside of the patient's body). (cdc.gov)
  • 2 The referenced absorbed dose levels in this document are assumed to be from beta, gamma, or x radiation. (cdc.gov)
  • Neutron or proton radiation produces many of the health effects described herein at lower absorbed dose levels. (cdc.gov)
  • Through the Joint IAEA/WHO postal audits and IAEA/WHO SSDL network's calibration activities, we can ensure accurate dosimetry so cancer patients receive the right dose of radiation. (who.int)
  • These factors include the dose (how much), the duration (how long), and the type of radiation. (cdc.gov)
  • The dose contribution due to photonuclear reactions during radiotherapy / by Peter D. Allen and M. Anwar Chaudhri. (who.int)
  • In the multi-institutional phase II study TransTasman Radiation Oncology Group FASTRACK II, Shankar Siva, Ph.D., of the Peter MacCallum Cancer Centre and the University of Melbourne in Australia, and colleagues found that high-dose radiation is an effective treatment option for older patients with kidney cancer who are ineligible for surgery. (msdmanuals.com)
  • Patients now have access to care that helps enable precise Stereotactic Body Radiotherapy (SBRT). (brainlab.com)
  • MRI offers several theoretical advantages over CT to guide SBRT for prostate cancer, including the ability to aggressively reduce planning margins needed for radiation due to enhanced imaging capabilities. (uclahealth.org)
  • MRI-guidance offers a statistically significant reduction in acute grade GU as well as GI toxicity for prostate SBRT," said Dr. Amar Kishan, vice chair of clinical and translational research in the Departments of Radiation Oncology and Urology at UCLA Health Jonsson Comprehensive Cancer Center. (uclahealth.org)
  • it provides a basic introduction of the technology available, the applications in the management of acoustic neuromas (including the role of the neurotologist/ neurosurgeon in treatment planning), and the controversies regarding the use of radiation for the management of these tumors. (medscape.com)
  • In traditional EBRT, the field or treatment area is defined by the size and shape of the collimator, and several portals or fields are used to direct the radiation beam to the tumor and the surrounding tissue. (medscape.com)
  • This protocol describes the use of a fully automated system, the Radiation Planning Assistant (RPA), to create high-quality radiation treatment plans. (jove.com)
  • It is a combination of specially developed in-house software that uses an application programming interface to communicate with a commercial radiotherapy treatment planning system. (jove.com)
  • The necessary inputs to the system are a Treatment Plan Order, approved by the radiation oncologist, and a simulation computed tomography (CT) image, approved by the radiographer. (jove.com)
  • The RPA then generates a complete radiotherapy treatment plan. (jove.com)
  • For head/neck treatment plans, after the normal tissue and some of the target structures are automatically delineated on the CT image, the radiation oncologist must review the contours, making edits if necessary. (jove.com)
  • In radiotherapy clinics, the International Atomic Energy Agency (IAEA) recommends 1 treatment planner per 300 patients, and 1 radiation physicist per 400 patients treated annually 1 . (jove.com)
  • The German Society for Radiation Oncology (DEGRO) working group of young clinicians and scientists (yDEGRO) and the DEGRO representation of associate and full professors (AKRO) are aware of the essential role of radiation oncology in multidisciplinary treatment approaches. (uni-muenchen.de)
  • Personalized emphasizes biology-directed individualization of radiation treatment. (uni-muenchen.de)
  • In this retrospective study, we sought to describe and analyse the presenting clinical features in our cohort, and evaluate possible predictors of severity and chronicity in women with radiation-induced bowel injury after treatment for cervical and endometrial cancers. (ucl.ac.uk)
  • Univariate analysis showed increasing age, smoking, extended field radiation, cervical cancer treatment and the need for surgical intervention to be significant predictors for severity of ongoing disease at last follow-up. (ucl.ac.uk)
  • Daily bladder variations make it difficult to utilize standard radiotherapy as a primary treatment option for muscle-invasive bladder cancer. (avmi.net)
  • If a five-fraction regimen of breast cancer is proven to be non-inferior, this will result in a significant improvement in the access to radiotherapy, as well as reduced costs of treatment. (authorea.com)
  • Radiation treatment or radiotherapy is the use of precisely calculated doses of high energy X-rays to treat parts of the body where there is cancer. (calcuttayellowpages.com)
  • Radiation necrosis and diffuse cerebral atrophy are considered long-term complications of radiotherapy that occur from months to decades after radiation treatment. (medscape.com)
  • The Australian Government also approved budget item for the treatment of early stage breast cancer using targeted intraoperative radiotherapy and patients can avail of this treatment from 1 September 2015. (wikipedia.org)
  • In the CRT arm, there were issues of compliance, with 32% of patients assigned to CRT receiving inappropriate radiation and 25% of patients failing to initiate treatment within 10 weeks post surgery, the protocol-specified time limit. (cancernetwork.com)
  • Radiotherapy is a medical treatment that involves firing a beam of radiation (usually one similar to x-rays) at a particular part of the body. (vethelpdirect.com)
  • Not all referral centres will have radiotherapy facilities, so if your pet needs this kind of treatment, then you may need to travel further than usual to find it. (vethelpdirect.com)
  • Most of the illnesses that benefit from treatment with radiotherapy are different forms of cancer. (vethelpdirect.com)
  • This involves an injection of a radioactive substance (iodine-131) rather than treatment with a beam of radiation. (vethelpdirect.com)
  • As with any medical treatment, there are some risks involved in radiotherapy. (vethelpdirect.com)
  • Late side-effects of radiation treatment involve damage to slow-growing cells, such as those in the brain, spine, eyes, heart, or bones. (vethelpdirect.com)
  • How can I access radiotherapy treatment for my cat? (vethelpdirect.com)
  • If you or your vet think that your cat may have a tumour that could benefit from treatment with radiotherapy, you can be referred to a specialist to discuss it further. (vethelpdirect.com)
  • Soon after the discovery of X-rays by Wilhelm Conrad Röntgen in 1895, ionizing radiation was utilized for cancer treatment. (springer.com)
  • Recently, treatment outcomes have been improved in conjunction with a reduction in toxicity through technological innovations such as intensity modulated radiotherapy or stereotactic body radiotherapy. (springer.com)
  • The desire for technologically advanced treatment options is growing, which is driving the market for radiation oncology. (researchandmarkets.com)
  • In some cases, additional treatment with medications or radiation could be necessary to prevent the tumor from returning. (medicinenet.com)
  • Respondents were asked to fill in questionnaires regarding treatment techniques and to outline target volumes for the boost phase of radiotherapy. (bepress.com)
  • The majority (83%) of the radiation oncologists used at least two phases of treatment. (bepress.com)
  • CONCLUSION: There was a variety of radiation treatment techniques in this trans-Canada survey. (bepress.com)
  • Radiation Treatment for Cervical Esophagus: Patterns of Practice Study in Canada, 1996" International Journal of Radiation Oncology, Biology, Physics Vol. 47 Iss. (bepress.com)
  • A new Italian study found that accelerated hypofractionated radiotherapy was an effective and safe treatment for malignant pleural mesothelioma (MPM). (survivingmesothelioma.com)
  • A comprehensive textbook of radiotherapy and related radiation physics and oncology for use by all those concerned with the uses of radiation and cytotoxic drugs in the treatment of patients with malignant disease. (scopewe.com)
  • Imaging is now an essential part of radiotherapy, relevant for both the treatment and preparation of a patient's treatment. (scopewe.com)
  • You will first meet with a radiation oncologist for a review of your medical history, a physical examination, and to discuss your treatment options. (materprivate.ie)
  • The "surgical and large bore procedures in malignant pleural mesothelioma and radiotherapy" (SMART) trial will compare the PTM rates of mesothelioma patients who have had various types of treatment interventions, with or without prophylactic radiotherapy. (survivingmesothelioma.com)
  • During treatment of breast cancer, Radiotherapy to the Supraclavicular fossa region results in absorption of radiation by the thyroid gland and consequently leads to hypothyroidism in 40% of patients. (ac.ir)
  • This training ensures users are competent and confident using HyperArc® high-definition radiotherapy within the Eclipse™ treatment planning system and TrueBeam® radiotherapy system. (varian.com)
  • Radiotherapy treatment planning / Richard F. Mould. (who.int)
  • The study was carried out to exhaust the scientific literature regarding surgery associated with radiotherapy in patients suffering from metastatic spinal cord compression and to assist in the decision of oncology physicians and professionals in choosing the best treatment for the patient. (bvsalud.org)
  • The researchers carried out a descriptive study using bibliometric and scientometric methods and found that the combination of surgery with postoperative radiotherapy is effective and more efficient than these alone for the treatment of patients affected by metastatic neurological compression. (bvsalud.org)
  • Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
  • Radiotherapy is a mode of treatment that is often used for malign neoplasms of the head and neck and has a significant cure rate, although it is associated with various oral complications 2 . (bvsalud.org)
  • Thus, the aim of the present study was to evaluate, in a subpopulation, the mouth-opening ability of patients subjected to radiotherapy treatment in the area of the head and neck. (bvsalud.org)
  • Patients who have often gone through months of treatment prior to radiation, can safely undergo three instead of five weeks of postmastectomy radiation and have similar outcomes," Wong said. (msdmanuals.com)
  • The radiotherapy workflow for prostate cancer is associated with systematic uncertainty stemming from the registration between the computed tomography (CT) and magnetic resonance (MR) images. (lu.se)
  • In conclusion, the work presented in this thesis demonstrates that an MRI-only workflow for radiotherapy of prostate cancer can be clinically implemented. (lu.se)
  • Approximately one in five of the radiotherapy cases are prostate cancer patients and for those, MRI simulation is part of the standard clinical care. (philips.com)
  • In its traditional CT-MRI simulation and planning workflow, Ingenia has been invaluable for its superb, tunable soft-tissue contrast, particularly for planning prostate cancer cases, according to Prof. Heikki Minn, MD, Radiation Oncologist at TYKS. (philips.com)
  • Using MR-only simulation and planning would give us a 'onestop- shop' workflow for imaging, contouring and planning of radical radiotherapy for patients with prostate cancer," he says. (philips.com)
  • Our final results are expected later this year, but we are extremely optimistic by what we're seeing, and hope this technology will soon begin to offer men undergoing radiotherapy for prostate cancer better outcomes. (uclahealth.org)
  • Patients at high risk for tumor recurrence may benefit from more aggressive altered fractionation schedules in order to reduce the overall time from surgery to completion of radiotherapy. (biomedcentral.com)
  • 32 patients were evaluated six months after completion of radiotherapy sessions to treat cancer in the head and neck. (bvsalud.org)
  • PURPOSE: To assess the patterns of practice among Canadian radiation oncologists who treat esophageal cancers, using a trans-Canada survey, completed at the end of 1996. (bepress.com)
  • METHODS AND MATERIALS: One of 3 case presentations of different stages of cervical esophageal cancer was randomly assigned and sent to participating radiation oncologists by mail. (bepress.com)
  • Radiation oncologists from 26 of 27 (96%) of all Canadian centers participated. (bepress.com)
  • One session was exclusively devoted to the challenging issues of dosimetry in small and non-standard radiotherapy beams. (iaea.org)
  • In patients having lumpectomy for breast cancer, the TARGIT-A(lone) randomized controlled trial (recruitment from 2000-2012) tested whether TARGIT within a risk-adapted approach is non-inferior to conventional course of external beam postoperative radiotherapy given over several weeks. (wikipedia.org)
  • Decompression surgery and postoperative radiotherapy was mostly palliative. (bvsalud.org)
  • Postoperative radiotherapy is reserved for cases in which histopathologic analysis of the removed specimen reveals features suggesting a high risk for local recurrence. (medscape.com)
  • Purpose Scientific and clinical achievements in radiation, medical, and surgical oncology are changing the landscape of interdisciplinary oncology. (uni-muenchen.de)
  • The first term Innovative radiation oncology comprises the promotion of preclinical research and clinical trials and highlights the development of a national committee for strategic development in radiation oncology research. (uni-muenchen.de)
  • The term together underpins collaborations within radiation oncology departments as well as with other partners in the clinical and scientific setting. (uni-muenchen.de)
  • A study from the Journal of Clinical Oncology has reviewed the link between radiotherapy and surgery. (survivingmesothelioma.com)
  • Walter & Miller's Textbook of Radiotherapy has become the core text for therapeutic radiography students and an important introductory text for trainee radiologists and clinical physicists. (scopewe.com)
  • Theproblem with tumoricidal doses of external beam radiation is that normal tissues can also be affected. (oncolink.org)
  • With submillimeter accuracy, high doses of radiation can be concentrated in the tumor, thus sparing adjacent healthy tissue. (charite.de)
  • In the current prospective study, 20 malignant pleural mesothelioma patients underwent radical pleurectomy/decortication followed by high doses of radiation. (survivingmesothelioma.com)
  • The IAEA/WHO dosimetry audit programme helps hospitals in the Member States, either directly or through national audit networks, to have confidence in the radiation doses they are delivering to their patients. (who.int)
  • However, the salivary gland can recover in patients receiving lower doses of radiation. (cdc.gov)
  • This publication presents the proceedings of an international symposium on standards, applications and quality assurance in medical radiation dosimetry. (iaea.org)
  • The symposium provided a forum for physicists and scientists of medical institutions, research centres and standards laboratories to discuss advances in radiation dosimetry made during the past decade and to exchange scientific knowledge. (iaea.org)
  • The topical sessions included all specialties in radiation medicine (radiation oncology, nuclear medicine and diagnostic radiology) and radiation protection dosimetry, with a specific focus on those areas where the standardization of dosimetry has improved in recent years (brachytherapy, diagnostic radiology and nuclear medicine). (iaea.org)
  • The publication summarizes the present status and outlines future trends in medical radiation dosimetry, and also identifies possible areas for improvement. (iaea.org)
  • The IAEA/WHO Network of SSDLs improves the accuracy of radiation dosimetry related to medical applications of radiation, other applications of ionizing radiation (for example, in industry and agriculture), and radiation protection. (who.int)
  • New technology combines radiotherapy with real-time detection of cancer cells to target moving tumors or multiple metastases. (arthealth.com)
  • By preventing neutrophil-dependent Notch activation, via blocking degranulation, we were able to significantly offset the radiation-enhanced metastases. (nature.com)
  • Radiotherapy for head and neck cancers has been examined as a possible risk factor for second primary cancers, but the results have been equivocal. (nih.gov)
  • Radiotherapy for head and neck cancers can result in extensive damage to the salivary glands, significantly affecting patient quality of life. (cdc.gov)
  • A key principle in the evolution of radiotherapy has always been the reduction of normal tissue toxicity" said Jeremy Ruben MD, MBBCh (Hons), FCRadOnc (SA), FRANZCR, Mmed, Radiation Oncologist, Director of Training, William Buckland Radiotherapy Centre, The Alfred. (brainlab.com)
  • Once all of this is complete, your radiation oncologist reviews all the information and writes a 'prescription' which outlines exactly how much radiation you will receive and where. (materprivate.ie)
  • Your radiation oncologist and nurse will see you regularly to follow your progress, check on any side effects you are experiencing, and address any concerns you may have. (materprivate.ie)
  • Over the last decade, the efficacy and use of stereotactic radiation has increased dramatically because of improvements in medical imaging, computer technology, and advanced delivery devices. (medscape.com)
  • The market for radiation oncology is anticipated to be driven by technical developments that increase the efficacy and safety of treatments. (researchandmarkets.com)
  • A systematic review of partial breast irradiation (PBI) techniques (including TARGIT) versus whole breast radiotherapy, by Cochrane, found current evidence shows PBI provides slightly worse cancer control. (wikipedia.org)
  • Purpose: Breast cancer survivors have a high risk of cardiac death as a consequence of heart irradiation during left breast tangential radiotherapy (RT). (unicatt.it)
  • The radiation beam is then delivered through a collimator, which shapes the beam. (medscape.com)
  • Stereotactic radiotherapy allows dynamic beam shaping and intensity modulation, providing flexibility and optimal tumor dosing. (medscape.com)
  • ExacTrac Adaptive Gating helps to ensure that the radiation beam is delivered only when the tumor is in a pre-defined target area. (brainlab.com)
  • Images were obtained retrospectively from cone-beam computed tomography (CBCT) scans used for daily positioning of four dogs undergoing fractionated image-guided radiotherapy (IGRT). (avmi.net)
  • The aim of this study was to compare thyroid gland radiation absorption during radiotherapy with different anterior-posterior beam radiation of 6-15 and 15-15 MV photon beam energies. (ac.ir)
  • Because healthy tissues are typically more resistant to the effects of radiation, tumor cells are killed while the surrounding tissue eventually recovers. (medscape.com)
  • Today, through the use of sophisticated imaging devices and 3-dimensional treatmentplanning computers, stereotactic radiotherapy allows much more specific targeting of a lesion, with significantly less radiation delivered to surrounding healthy tissues. (medscape.com)
  • TARGIT is a method where the radiation is applied during an operation and targeted to the peri-tumoural tissues. (wikipedia.org)
  • Radiation side-effects involve damage to cells in normal body tissues in the area that is being treated. (vethelpdirect.com)
  • demonstrated that altered fraction schedules are a valuable alternative to chemoradiation as they provide similar gains in reduction of overall mortality compared to standard radiation alone in the definitive therapeutic setting. (biomedcentral.com)
  • We review the possible roles for calorie restriction (CR) and very low carbohydrate ketogenic diets (KDs) in modulating the five R's of radiotherapy to improve the therapeutic window between tumor control and normal tissue complication probability. (springer.com)
  • At such gatherings, a bigger emphasis is placed on raising awareness of the advantages and therapeutic benefits that radiation provides for a variety of cancers. (researchandmarkets.com)
  • We evaluated the impact of therapeutic radiation for oral cancer on the risk of second primary cancers with data from the Surveillance, Epidemiology, and End Results (SEER) program for 1973-1999. (nih.gov)
  • Used with disease headings for the therapeutic use of ionizing and nonionizing radiation. (bvsalud.org)
  • Melbourne, Australia, June 21, 2013-Alfred Health's William Buckland Radiotherapy Centre (WBRC) in Melbourne announced that they have begun treating cancer patients using Brainlab ExacTrac® Adaptive Gating. (brainlab.com)
  • Outcome in a prospective phase II trial of medically inoperable stage I non-small-cell lung cancer patients treated with stereotactic body radiotherapy. (brainlab.com)
  • Fifteen (19%) women in the cervical cancer group had radiation-induced bowel injury requiring surgical intervention compared with five (6.7%) in the endometrial cancer group. (ucl.ac.uk)
  • The impact of radiation-induced bowel injury and the effect on cancer survivorship warrants further research into investigation of predictors of severe late toxicity. (ucl.ac.uk)
  • In our model, adaptive radiotherapy techniques for canine bladder cancer showed significant reduction in rectal volume irradiated when compared to nonadaptive techniques, while maintaining appropriate bladder coverage. (avmi.net)
  • A meta-analysis by authors of the TRAGIT-A trial found that PBI reduced non-breast cancer and overall mortality compared with whole breast radiation. (wikipedia.org)
  • The radiation damages the cells in the cancer, causing them to die. (vethelpdirect.com)
  • A multidisciplinary approach to treating cancer must include the medical specialty of radiation oncology (radiotherapy/radiotherapy). (researchandmarkets.com)
  • 6 Department of Radiation Oncology, Cancer Center Amsterdam, Amsterdam UMC (VUmc location), the Netherlands. (nih.gov)
  • Earlier this week, Stanford Medicine launched a new method of delivering radiation that uses signals from cancer-targeting molecules called tracers to target tumors in real time. (arthealth.com)
  • Retracted: Risk Factors of Acute Radiation-Induced Lung Injury Induced by Radiotherapy for Esophageal Cancer. (bvsalud.org)
  • Radiotherapy for oral cancer appears to be a risk factor for second primary tumors. (nih.gov)
  • Radiotherapy is one of the most effective approaches to achieve tumor control in cancer patients, although healthy tissue injury due to off-target radiation exposure can occur. (nature.com)
  • In this study, we used a model of acute radiation injury to the lung, in the context of cancer metastasis, to understand the biological link between tissue damage and cancer progression. (nature.com)
  • We exposed healthy mouse lung tissue to radiation before the induction of metastasis and observed a strong enhancement of cancer cell growth. (nature.com)
  • The IAEA collaborates closely with WHO on their global cancer initiatives in cervical, childhood and breast cancers - including diagnostic imaging, radiology and nuclear medicine, and radiotherapy. (who.int)
  • The IAEA also assists countries in setting up facilities for radiotherapy and medical imaging and to acquire equipment for diagnosing cardiovascular disease and treating cancer. (who.int)
  • RÉSUMÉ La présente étude transversale basée sur un questionnaire a évalué les connaissances et les attitudes en matière de cancer du sein de 387 Iraniens ayant fait des études (302 femmes et 85 hommes) et travaillant ou étudiant dans deux universités iraquiennes, ainsi que les pratiques des femmes de l'échantillon en matière d'auto-examen des seins. (who.int)
  • The annual meeting of the American Society for Radiation Oncology was held from Oct. 1 to 4 in San Diego and attracted approximately 11,000 participants from around the world, including physicians, oncology nurses, radiation therapists, biologists, physicists, and other cancer researchers. (msdmanuals.com)
  • Before reading this chapter you should have read Chapter 5, in particular the sections on the detection of ionizing radiation, absorption and scattering of ϒ-rays. (taylorfrancis.com)
  • 1998. Food preservation using ionizing radiation. (cdc.gov)
  • This Public Health Statement is the summary chapter from the Toxicological Profile for ionizing radiation . (cdc.gov)
  • This public health statement tells you about ionizing radiation and the effects of exposure. (cdc.gov)
  • It does not tell you about non-ionizing radiation, such as microwaves, ultrasound, or ultraviolet radiation. (cdc.gov)
  • Exposure to ionizing radiation can come from many sources. (cdc.gov)
  • You can learn when and where you may be exposed to sources of ionizing radiation in the exposure section below. (cdc.gov)
  • However, it's unknown how many of the 1,467 current or former NPL sites have been evaluated for the presence of ionizing radiation sources. (cdc.gov)
  • As more sites are evaluated, the sites with ionizing radiation may increase. (cdc.gov)
  • This information is important because exposure to ionizing radiation may harm you and because these sites may be sources of exposure. (cdc.gov)
  • Even in the event that you are exposed, it does not necessarily mean you will be harmed or suffer longterm health effects from exposure to ionizing radiation. (cdc.gov)
  • If you are exposed to ionizing radiation, many factors determine whether you'll be harmed. (cdc.gov)
  • What is ionizing radiation? (cdc.gov)
  • To explain what ionizing radiation is, we will start with a discussion of atoms, how they come to be radioactive, and how they give off ionizing radiation. (cdc.gov)
  • Of the different types and sources of ionizing radiation, this profile will discuss the three main types: alpha, beta, and gamma radiation. (cdc.gov)
  • Before defining ionizing radiation, it is useful to first describe an atom. (cdc.gov)
  • Ionizing radiation is energy that is carried by several types of particles and rays given off by radioactive material, x ray machines, and fuel elements in nuclear reactors. (cdc.gov)
  • Contrary to X-ray imaging, computed tomography, or nuclear medicine, the MRI technique is not based on ionizing radiation. (lu.se)
  • Gynecologic cancers were among the first malignancies treated with ionizing radiation, more than a century ago. (medscape.com)
  • Evidence suggests that certain environmental factors, such as radiation exposure and infection, may increase the risk of developing GCTs. (medicinenet.com)
  • Radiation exposure, known to cause DNA damage, may be a potential source of field cancerization of the upper aerodigestive tract. (nih.gov)
  • Fig. 1: Radiation exposure in healthy lung tissue enhances metastasis. (nature.com)
  • Fig. 2: Radiation exposure induces the infiltration and local activation of lung neutrophils. (nature.com)
  • Fig. 6: Radiation exposure boosts Notch signaling and stemness in metastatic cells. (nature.com)
  • The concept of cutaneous radiation syndrome (CRS) was introduced in recent years to describe the complex pathological syndrome that results from acute radiation exposure to the skin. (cdc.gov)
  • In addition, there is considerable interest in delineating the mechanisms by which stem cells survive radiation exposure and promote tissue regeneration. (cdc.gov)
  • Progenitor cells are characterized as c-Kithigh/alpha-amylase+ and are resistant to X rays (=5 Gy).We further isolated a radiosensitive acinar counterpart, characterized as c-Kitlow/alpha-amylase+, which is effectively killed by exposure to 2 Gy X ray of radiation. (cdc.gov)
  • Such techniques would avoid the use of painful biopsies or radiation exposure through computed tomography examinations while providing improved accuracy and detail in larger volumes. (lu.se)
  • Radiation necrosis can occur when radiotherapy is used to treat primary CNS tumors, metastatic disease, or head and neck malignancies. (medscape.com)
  • Fig. 8: Inhibition of Notch signaling attenuates the radiation-driven enhancement of metastatic growth in vivo. (nature.com)
  • However, for women with distant metastatic disease at presentation, cure is unlikely, although palliative radiotherapy frequently improves a patient's quality of life when used to relieve symptoms. (medscape.com)
  • Patients treated with radiation only (RR=1.64, 95%CI=1.18-2.29) or radiation with surgery (RR=1.49, 95%CI=1.07, 2.06) had elevated risks of developing a second primary tumor, whereas patients treated with surgery only did not appear to be at increased risk (RR=1.28, 95%CI=0.93, 1.76). (nih.gov)
  • The conference featured educational courses focusing on radiation, surgical, and medical oncology. (msdmanuals.com)
  • The use of ADT and the prolongation of adjuvant ADT with radiotherapy provides clinically meaningful benefit and should remain the standard of care, with level 1 evidence," he said during a presentation at the American Society for Radiation Oncology annual meeting. (medpagetoday.com)
  • This is a joint project with the department of Medical Radiation Physics, Lund at Lund University. (lu.se)
  • Radiotherapy is commonly used to treat human cancers - but is it an option for our cats? (vethelpdirect.com)
  • In very rare cases, new cancers may form in the treated area as a result of the radiation. (vethelpdirect.com)
  • Cancers in the lungs, for example, move with each breath, while tumors that have metastasized to many places in the body can require repeated radiation sessions. (arthealth.com)
  • To evaluate the effect of timing of radiotherapy (RT) on survival in patients with newly diagnosed primary glioblastoma (GBM) treated with the same therapeutical protocol. (springer.com)
  • As a result, stereotactic radiation has become a viable and useful primary management alternative for patients with cerebellopontine angle and/or skull base tumors , including acoustic neuromas (also known as vestibular schwannomas), meningiomas , and paragangliomas. (medscape.com)
  • Adding ADT to radiotherapy significantly improved 12-year rates of MFS, the primary endpoint (HR 0.83, 95% CI 0.77-0.89), increasing from 43% without ADT to 51% with it. (medpagetoday.com)
  • Radiation beams can be shaped, sized and directed specifically to the shape and location of your tumour, preventing the rays from hitting healthy tissue. (materprivate.ie)
  • Fig. 4: Radiation-primed neutrophils perturb the lung tissue environment. (nature.com)
  • After surgeons removed as much of the visible mesothelioma tumor and surrounding tissue as possible, patients received 50Gy of radiation to the effected side of their chest, delivered in 25 fractions. (survivingmesothelioma.com)
  • The chewing muscles or the temporomandibular joint (TMJ), when they are enclosed in a radiation field, may lead to the formation of tissue fibrosis, muscle spasms and restricted mouth opening, or trismus 3 . (bvsalud.org)