BINOL is a precursor for another chiral ligand called BINAP. (wikipedia.org)
Aside from the starting materials derived directly from the chiral pool, (R)- and (S)-BINOL in high enantiopurity (>99% enantiomeric excess) are two of the most inexpensive sources of chirality for organic synthesis, costing less than US$0.60 per gram when purchased in bulk from chemical suppliers. (wikipedia.org)
Many important chiral ligands are constructed from the binaphthyl scaffold and ultimately derived from BINOL as a starting material, BINAP being one of the most well known and important. (wikipedia.org)
In a different stoichiometric ratio (1:1 BINOL/LiAlH4 instead of 2:1), the chiral reducing agent BINAL (lithium dihydrido(binaphthoxy)aluminate) is produced. (wikipedia.org)
As a validating case study, we combined published enantioselectivity datasets that employ 1,1′-bi-2-naphthol (BINOL)-derived chiral phosphoric acids for a range of nucleophilic addition reactions to imines and developed statistical models. (nature.com)
The chiroptical properties of enantiopure complexes and their catalytic applications in asymmetric oxidative coupling of 2‐naphthol to chiral 1,1'‐Bi‐2‐naphthol (BINOL) achieved in good yield and ee were discussed. (jyu.fi)
Asymmetric oxidative1
S)-BINOL can be prepared directly from an asymmetric oxidative coupling of 2-naphthol with copper(II) chloride. (wikipedia.org)