AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth Care
Mice, Inbred StrainsRabbitsSpecies SpecificityCrosses, GeneticMice, Inbred DBAChromosome MappingMice, Inbred C57BLMice, Inbred C3HQuantitative Trait LociMice, Inbred AKRPhenotypeMice, Inbred AInbreedingRats, Inbred StrainsSequence Analysis, DNAChromosomes, MammalianMuridaeGenetic LinkageMice, Inbred BALB CGenetics, BehavioralGenetic VariationDisease Models, AnimalGenotypeAnimals, Outbred StrainsMolecular Sequence DataMice, CongenicRecombination, GeneticDisease SusceptibilityMice, Inbred CBAMutationAllelesRNA, Ribosomal, 16SAmino Acid SequenceGenesHybridization, GeneticDNA, RibosomalEscherichia coliBacterial Typing TechniquesFlurothylVirulenceBase SequenceGenes, BacterialQuantitative Trait, HeritablePolymerase Chain ReactionNucleic Acid HybridizationRats, Inbred BNGenomeTime FactorsPolymorphism, Restriction Fragment LengthCloning, MolecularChromosomesGenetic MarkersAnimals, LaboratoryImmune SeraPolymorphism, GeneticAnti-Bacterial AgentsLeukemia Virus, MurineMicrobial Sensitivity TestsMice, Mutant StrainsDNA, BacterialImmunogeneticsCulture MediaBehavior, AnimalSerotypingLiverPhylogenySpleenPlasmidsHaplotypesRodent DiseasesH-2 AntigensBase CompositionAntigens, BacterialAnimals, CongenicBlotting, SouthernOrgan SizeAnimals, WildImmunity, InnateGenes, rRNAChimeraScent GlandsSequence Homology, Nucleic AcidGenetic Predisposition to DiseaseBody WeightRNA, MessengerDrug Resistance, MicrobialKineticsAnimals, Inbred StrainsDNAMajor Histocompatibility ComplexMice, Inbred NZBGenome, BacterialCholesterol, DietaryGene Expression Regulation, BacterialSoil MicrobiologyPolymorphism, Single NucleotideRNA, BacterialDiet, AtherogenicUrethaneDNA Primers
Guinea pigsBalbWistarC57BLMice and ratsMicrosomesLiverSerumAcuteHepaticLaboratoryRodentsSecretionMouseAlbinoOrallyInhalationHippocampalLungSpeciesEmbryosAirwayNeuronalMaleTissueIncidenceGlucoseModelAnimalsResponsesBoneHumanBiologyProteinCatsHighlyResearchConditionsOrderGrowthProductionModelsDevelopmentTestStudy
Guinea pigs4
  • A survey of various species by immunoblot analysis with several antibodies revealed little if any epitope relatedness among microsomal proteins from rats, mice, rabbits, hamsters, squirrel monkeys, guinea pigs, or humans. (nih.gov)
  • This important part of their business includes research animal models such as inbred, outbred, disease and immunodeficiency models, including mice, rats, hamsters, guinea pigs and rabbits to name a few examples. (citeab.com)
  • Guinea pigs are important animal models for human disease, and both outbred and inbred lines are utilized in biomedical research. (cdc.gov)
  • To avoid charges, cancellations for timed mated rats, mice, guinea pigs, and hamsters must be received one week prior to mating date, however, cancelled orders for timed mated rabbits will be charged at full price regardless of the amount of notice supplied. (inotivco.com)
Balb2
  • Two inbred mouse strains (BALB/c and A/J) and one outbred strain (ICR) were subcutaneously injected with saline solutions containing penicillin G (1.25, 2.5 and 5 mg/mouse), D-penicillamine (0.5, 1 and 2 mg/mouse), or barbital (2 mg/mouse) into one hind footpad and saline only was injected into the contralateral footpad. (go.jp)
  • These mice have both BALB/c inbred and NIH(S) outbred stock in their genetic background. (vivobio.com)
Wistar2
  • Female Wistar rats were exposed orally to 200 and 400 ppm propineb (Zn-containing dithiocarbamate) and 250 ppm maneb (Mn-containing dithiocarbamate), from the 6th day of gestation up to birth. (go.jp)
  • Hepatoprotective and antioxidant activities of betulin as part of mayonnaise samples has been investigated in vivo on the model of toxic hepatitis initiated by carbon tetrachloride in male Wistar rats weighing 210-265 g. (bvsalud.org)
C57BL2
  • C57BL/6J is an inbred strain, commonly used as a genetic background when genetically modified mice are utilised as models for human disease. (citeab.com)
  • Using a pair of black mice from the Granby farm, Little develops the C57BL and C57BR strains. (jax.org)
Mice and rats2
  • In mice and rats, females require mating stimulation for the maintenance of pregnancy. (nature.com)
  • one estimate of mice and rats used in the US alone in 2001 was 80 million. (wmflabs.org)
Microsomes3
  • Immunoblot analysis of rat microsomes illustrated the male specificity of cytochrome P450h expression which extended to extrahepatic tissues including kidney and lung. (nih.gov)
  • Thus, despite the high level of expression of cytochrome P450h in microsomes from adult male rats and the high catalytic activity of the purified protein for benzphetamine, this isozyme contributes only a small portion of the metabolism of this substrate in microsomes. (nih.gov)
  • Glucose rapidly increased DAG content and PKC enzyme activity in microsomes, but not in plasma membranes or other membranes, during a 30-min treatment of rat adipocytes. (jci.org)
Liver4
  • However, the vitamin A liver concentration in the study rats was significantly lower compared to the naive rats. (indexarticles.com)
  • To elucidate whether allergic bronchitis interferes with vitamin A metabolism, we measured the vitamin A levels in the serum, the lung, and the liver following repeated allergen challenge in a rat model and compared them to normal rats. (indexarticles.com)
  • birch bark in fat-containing products (for example mayonnaise) on the blood biochemical parameters and liver morphological structure of rats with initiated acute toxic hepatitis. (bvsalud.org)
  • The morphological structure of rats' liver was estimated by microscopy of prepared cuts of hepatic tissue. (bvsalud.org)
Serum1
  • Differential labeling of rat hepatic Golgi and serum very low density lipoprotein apoprotein B variants. (uchicago.edu)
Acute2
  • 1982. Acute inhalation toxicity of ammonia in rats with variable exposure periods. (cdc.gov)
  • We now have been utilizing the Inbred Lengthy- and Quick-Sleep mouse strains (ILS, ISS) and a recombinant inbred panel derived from them, the LXS, to research the genetic underpinnings of acute ethanol tolerance which is taken into account to be a threat issue for alcohol use issues (AUDs). (eumorphia.org)
Hepatic1
  • A panel of 30 monoclonal antibodies against rat hepatic microsomal cytochrome P450h (2C11) has been produced, purified, and characterized. (nih.gov)
Laboratory2
  • Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally occurring albino animals exist in the wild, e.g. (wikipedia.org)
  • When the use of laboratory animal is obligatory, the most appropriate specie, breed, and strain with the closest homology to humans must be chosen. (ommegaonline.org)
Rodents3
  • The first-floor rooms for rodents and rabbits, which are maintained under dark and light cycles and controlled environmental conditions for temperature, humidity, air pressure as per the regulatory requirements with the help of HVAC system. (org.in)
  • The ground floor houses majority the service areas (dehusking, washing, autoclaving, storage of animal feed and bedding material), procedure room for infectious studies (BSL2), and quarantine rooms for rodents and rabbits. (org.in)
  • Majority of rodents are bred under strictly inbred conditions. (org.in)
Secretion1
  • Rat granulosa cell apolipoprotein E secretion. (uchicago.edu)
Mouse4
  • It was the first mouse strain to have its genome sequenced, back in 2003. (citeab.com)
  • In the present collaborative study, popliteal lymph node (PLN) responses to penicillin G (an allergenic chemical), D-penicillamine (an autoimmunity-inducing chemical), and barbital (a negative reference chemical) were investigated in three different mouse strains by ten pharmaceutical companies. (go.jp)
  • SAMPs (senescence-accelerated mouse prones) are inbred mouse lines showing accelerated aging. (biomedcentral.com)
  • Even with the availability of inbred mouse strains transplantation studies have shown only modest success. (amegroups.org)
Albino1
  • L. C. Strong breeds a Bagg albino with an albino from Little 's stock and starts the first of many tumor-prone strains, called the A strain, known for mammary and lung tumors. (jax.org)
Orally1
  • rats of the main groups were orally administered mayonnaise once a day at a dosage of 1 ml for 21 days after the formation of the model pathology: OG-1 with the added betulin (1 mg per 1 kg of body weight), OG-2 without betulin. (bvsalud.org)
Inhalation2
  • After 14 days, repeated allergen inhalation challenges were performed in the sensitized rats for 2 weeks. (indexarticles.com)
  • 9) Allergen inhalation in sensitized BN rats causes an increase in production of tumor necrosis factor (TNF)-[alpha] and nitric oxide (NO) by alveolar macrophage and airways epithelial cells, and it can be inhibited by dexamethasone. (indexarticles.com)
Hippocampal2
  • Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures. (uchicago.edu)
  • Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures. (uchicago.edu)
Lung2
Species2
  • Registration is now open for the 2023 Rabbit R&D Webinar, co-hosted by Rabbit-Free Australia and CISS (Centre for Invasive Species Solutions). (rabbitfreeaustralia.org.au)
  • A strong social hierarchy (or 'pecking order') and territoriality help prevent inbreeding, giving species an adaptive advantage. (rabbitfreeaustralia.org.au)
Embryos1
  • The demonstration by researchers that castrated rabbit embryos of both sexes developed as females proved that testes are required for development of the male phenotype in mammals. (medscape.com)
Airway1
  • 5) The asthmatic rats have early airway responses and late airway response in high prevalence, (6) showing high levels of specific IgE on active immunization (6) and airway eosinophilia. (indexarticles.com)
Neuronal1
  • The authors performed histologic studies of neuronal survival in the rat hippocampus after traumatic brain injury and treatment with blood glutamate scavengers. (asahq.org)
Male2
  • Only 20-25% inhibition of benzphetamine metabolism was attained in microsomal preparations from adult male rats, and the antibodies did not influence the microsomal catalytic activity of immature males or females or adult females. (nih.gov)
  • Traumatic brain injury was induced on anesthetized male Sprague-Dawley rats by a standardized weight drop. (asahq.org)
Tissue2
  • This study was designed to determine whether tissue engineering could be used to reduce ventricular remodeling in a rat model of non-transmural, non-ST-elevation myocardial infarction. (pharmaceuticalintelligence.com)
  • Assessment of regional bone tissue perfusion in rats using fluorescent microspheres. (iu.edu)
Incidence1
  • L. C. Dunn breeds Strain 129, which later proves to have a high incidence of testicular cancer. (jax.org)
Glucose2
  • Preferential activation of microsomal diacylglycerol/protein kinase C signaling during glucose treatment (De Novo phospholipid synthesis) of rat adipocytes. (jci.org)
  • Glucose has been reported to increase the de novo synthesis of diacylglycerol (DAG) and translocate and activate protein kinase C (PKC) in rat adipocytes. (jci.org)
Model2
  • Objective: To examine whether repeated allergen challenges could increase vitamin A consumption in a rat model. (indexarticles.com)
  • The Brown Norway (BN) rat model has been extensively characterized and appears to be among the best animal models thus far described. (indexarticles.com)
Animals4
  • Natural infections in other Equidae, transmitted brain homogenates from infected ruminants, rabbits, cats, and ostriches have also horses to experimental animals. (cdc.gov)
  • Design: Allergic bronchitis was induced in 12 animals, and 12 rats remained naive. (indexarticles.com)
  • Aspartate aminotransferase and alkaline phosphatase activity in blood plasma of the experimental animals of the main group MG-1 reduced by 20.7 and 35.2% compared with indicators of the rats of the main group MG-2. (bvsalud.org)
  • The eradication of 'every last rabbit, cat and fox' provided the foundation for the reintroduction of native animals to Sturt National Park, in NW NSW. (rabbitfreeaustralia.org.au)
Responses1
  • In the three strains tested, the penicillin G and D-penicillamine injections resulted in approximately dose-dependent responses. (go.jp)
Bone1
  • Rezaee T, Bouxsein ML, Karim L. Increasing fluoride content deteriorates rat bone mechanical properties. (bouxseinlab.org)
Human1
  • Association of human, rat, and rabbit apolipoprotein E with beta-amyloid. (uchicago.edu)
Biology1
  • Although the biology of response is best characterized in rats, dogs have proven valuable in defining post-operative physiological adaptations. (biomedcentral.com)
Protein1
  • Effects of sex hormones on protein and collagen content of the temporomandibular joint disc of the rat. (dntb.gov.ua)
Cats1
  • Programs to eradicate invasive rats, cats, rabbits and goats have been a key to restoring the ecology on islands around the world according to a recent assessment of attempts on nearly 1,000 islands. (rabbitfreeaustralia.org.au)
Highly1
Research4
  • The optimal maintenance of guinea pig colonies, commercially and in research settings, relies on robust informed breeding programs, however, breeding data on specialized inbred strains are limited. (cdc.gov)
  • Right here, we've got used RNA-seq to look at the transcriptome of complete mind in 40 of the LXS strains eight hours after a saline or ethanol "pretreatment" as in earlier behavioral research. (eumorphia.org)
  • If customer's research project requires such litters, Envigo recommends ordering timed mated pregnant rats and mice which can litter at customer's facility. (inotivco.com)
  • Videos presentations on the environmental and economic impact of rabbits, the latest research on how RHDV is working, and Easter Bilby as an advocate for. (rabbitfreeaustralia.org.au)
Conditions1
Order1
Growth1
  • Other features include the fluid-like composition of the outer layer, which allows cells to move freely and regularly change position, and tensions surrounding the cerebellum mechanically straining its growth. (elifesciences.org)
Production3
  • Embryo transfer (ET) is an essential reproductive technology for the production of new animal strains and maintenance of genetic resources. (nature.com)
  • The production of female mice with pseudopregnancy induced using sonic vibration was as efficient as rats. (nature.com)
  • Results: The study rats showed severe bronchoconstriction after allergen challenge compared to the naive rats, and ex vivo TNF-[alpha] and NO production was significantly higher in the sensitized rats. (indexarticles.com)
Models1
  • For models fulfilled from Envigo Affiliates in Europe, the last stage of gestation for mice is over 17 days and for rats is over 18 days, each at shipping. (inotivco.com)
Development3
  • The Distinction between Development and Heredity in Inbreeding. (esp.org)
  • Based on biochemical parameters of rat blood plasma, it has been established that the administration of mayonnaise with betulin prevents the development of cytolic syndrome and suppresses the process of peroxidation by directly neutralizing free radicals. (bvsalud.org)
  • Foundation for Rabbit-Free Australia is calling for the appointment of a national rabbit management coordinator and the development of a National Action Plan for rabbits. (rabbitfreeaustralia.org.au)
Test2
  • The rats were randomly assigned to either the test group (n = 12) or the control group (n = 12). (indexarticles.com)
  • Allergic bronchitis was induced in the test group rats at the beginning of the study according to a protocol described by Du et al. (indexarticles.com)
Study1
  • The rats were weighed at the beginning and end of the study, and their food intake was measured every other day. (indexarticles.com)