In phylogenetic trees based on concatenated protein sequences or 16S rRNA, the genus Corynebacterium forms a distinct clade, within which is a distinct subclade, cluster I. The cluster is made up of the species C. diphtheriae, C. pseudotuberculosis, C. ulcerans, C. aurimucosum, C. glutamicum, and C. efficiens. (wikipedia.org)
Sing A , Hogardt M , Bierschenk S , Heesemann J . Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections. (cdc.gov)
Sing A , Berger A , Schneider-Brachert W , Holzmann T , Reischl U . Rapid detection and molecular differentiation of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by LightCycler PCR. (cdc.gov)
Corynebacterium diphtheriae is responsible for both endemic and epidemic diphtheria. (bvsalud.org)
Corynebacterium diphtheriae est responsable à la fois de la diphtérie endémique et épidémique. (bvsalud.org)
Strains1
Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
Ulcerans2
Contzen M , Sting R , Blazey B , Rau J . Corynebacterium ulcerans from diseased wild boars. (cdc.gov)
Rau J , Blazey B , Contzen M , Sting R . Corynebacterium ulcerans infection in roe deer ( Capreolus capreolus ). (cdc.gov)
Phylogenetic2
Based on studies of 16S-rRNA, they have been grouped into the subdivision of Gram-positive Eubacteria with high G:C content, with close phylogenetic relationship to Arthrobacter, Mycobacterium, Nocardia, and Streptomyces. (wikipedia.org)
Pascual C , Lawson PA , Farrow JA , Gimenez MN , Collins MD . Phylogenetic analysis of the genus Corynebacterium based on 16S rRNA gene sequences. (cdc.gov)
Genus5
Corynebacterium (/kɔːˈraɪnəbækˌtɪəriəm, -ˈrɪn-/) is a genus of Gram-positive bacteria and most are aerobic. (wikipedia.org)
The genus Corynebacterium was created by Lehmann and Neumann in 1896 as a taxonomic group to contain the bacterial rods responsible for causing diphtheria. (wikipedia.org)
A set of bacterial pathogens have been identified in central nervous infections in livestock and companion animals, although the most of descriptions are restricted to case reports and a lack of comprehensive studies involving CNS-related bacterial infections have been focused on a great number of domestic species. (bvsalud.org)
Clinical1
Central nervous system (CNS) infections comprise life-threatening clinical conditions in domestic species, and are commonly related to severe sequelae, disability, or high fatality rates. (bvsalud.org)
Species3
Two examples of CSIs are a two-amino-acid insertion in a conserved region of the enzyme phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase and a three-amino-acid insertion in acetate kinase, both of which are found only in Corynebacterium species. (wikipedia.org)
Additionally, 16 conserved signature proteins, which are uniquely found in Corynebacterium species, have been identified. (wikipedia.org)
Also, 21 conserved signature proteins are found only in members of cluster I. Another cluster has been proposed, consisting of C. jeikeium and C. urealyticum, which is supported by the presence of 19 distinct conserved signature proteins which are unique to these two species. (wikipedia.org)
Study2
The present study examined the possibilities that: (i) careful examination of Gram-stained sputum and culture plates may reveal a predominant bacterium such as Corynebacterium spp. (biomedcentral.com)
Partial DNA sequencing of this tox gene showed significant differences from sequences described for other Corynebacterium ulcerans strains and a higher degree of similarity to that of Corynebacterium diphtheria. (nih.gov)
Sing A , Berger A , Schneider-Brachert W , Holzmann T , Reischl U . Rapid detection and molecular differentiation of toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains by LightCycler PCR. (cdc.gov)
Toxigenic3
Respiratory diphtheria is a serious infection caused by toxigenic Corynebacterium diphtheriae, and disease transmission mainly occurs through respiratory droplets. (cdc.gov)
Potentially toxigenic species (eg, C diphtheriae, C ulcerans, C pseudotuberculosis ) have cystinase but not pyrazinamidase activity. (medscape.com)
As mentioned above, toxigenic strains of C ulcerans and C pseudotuberculosis are reported. (medscape.com)
Diphtheria toxin1
Sing A , Hogardt M , Bierschenk S , Heesemann J . Detection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections. (cdc.gov)
Infrared spectroscopy1
Fourier-transformed infrared spectroscopy as well as partial sequencing of the genes for 16S rRNA and RNA polymerase beta subunit (rpoB) clearly identified both strains as Corynebacterium ulcerans. (nih.gov)
Gene3
Using broad-range bacterial PCR producing a 1,400-base-pair fragment from the 16S rRNA gene, at least 24 clones were sequenced for each synovial tissue sample. (biomedcentral.com)
This study is the first to use broad-range PCR targeting the full 16S rRNA gene for detection of bacterial DNA in synovial tissue. (biomedcentral.com)
Three isolates (2 implant isolates and the oropharyngeal isolate) were subsequently characterized by MALDI-TOF-MS (matrix-assisted laser desorption-ionization time-of-flight mass spectroscopy) Bruker Daltonics, Fremont, CA, USA) and by 16S rRNA sequencing ( 5 ) and partial rpoB ( 6 ) gene sequencing ( Table ). (blogspot.com)
Nontoxigenic1
Nontoxigenic tox-bearing Corynebacterium ulcerans infection among game animals, Germany. (nih.gov)
Pseudodiphtheriticum1
In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum. (medscape.com)
the co-infection Mycobacterium bovis/Mycobacterium avium found in a poultry farmer was the first such co-infection in Chad related to human tuberculosis. (panafrican-med-journal.com)
Isolates1
This isolate and additional isolates from mixed infections of the implants of 3 other ferrets were subsequently identified as C. ulcerans by our diagnostic laboratory (Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA) and by the Centers for Disease Control and Prevention (Atlanta, GA, USA) by use of the API Coryne strip system. (blogspot.com)
Diphtheriae infection1
C diphtheriae infection typically is characterized by a local inflammation, usually in the upper respiratory tract, associated with toxin-mediated cardiac and neural disease. (medscape.com)
Zoonotic2
These results indicate that wild game could be a reservoir for zoonotic Corynebacterium ulcerans. (nih.gov)
Indeed, this finding highlights the importance of the zoonotic aspect of mycobacterial diseases and proves the value of molecular characterization in the tuberculosis surveillance. (panafrican-med-journal.com)
Contzen2
Contzen M , Sting R , Blazey B , Rau J . Corynebacterium ulcerans from diseased wild boars. (cdc.gov)
Rau J , Blazey B , Contzen M , Sting R . Corynebacterium ulcerans infection in roe deer ( Capreolus capreolus ). (cdc.gov)
Detection1
An average CTC detection rate of 77.8% was found and the average (range) total CTC count was 6.4 (0-27), 101.8 (0-255), and 3.2 (0-10), and the average mesenchymal CTC count (both single and clustered cells) was zero, 97.6 (0-255), and 0.2 (0-1) for M0, M1TN, and M1TP, respectively. (bvsalud.org)
Occurs1
Infection with Corynebacterium ulcerans occurs sporadically throughout the world, and in the United Kingdom it has emerged as the most common cause of diphtheria-like disease ( 1 ). (blogspot.com)
Laboratory1
For this reason, clinical suspicion of diphtheroid infection requires communication with the microbiology laboratory so that the appropriate cultures can be processed. (medscape.com)
Bacterial2
Usually, the initial arthritogenic bacterial infection affects the urogenital tract (for example, Chlamydia trachomatis ) or the digestive tract ( Yersinia , Salmonella or Shigella spp. (biomedcentral.com)
Arthritogenic bacterial DNA and RNA from Chlamydia trachomatis , Chlamydophila pneumoniae , and Yersinia pseudotuberculosis have been detected by PCR in synovial samples from patients with ReA and UA. (biomedcentral.com)
Studies1
A systematic electronic search in three databases, MEDLINE, Scopus, and Web of Science, was conducted in December 2021 to find interventional studies with adult patients undergoing external radiotherapy who received an educational session with virtual reality before or during the treatment. (bvsalud.org)
Skin2
Most recently, an increase in nondiphtherial corynebacterial infections of the skin and soft tissues has been reported. (medscape.com)
This organism has been implicated in bovine mastitis and can cause skin infections and a diptheria-like disease in humans. (up.ac.za)
Dead1
one was found dead, the other had been shot. (nih.gov)
Table1
Microbiological culture of a purulent discharge from the implant margin yielded a polymicrobial infection that included an organism identified as C. ulcerans by the API Coryne strip system (bioMérieux, Durham, NC, USA) ( Table ). (blogspot.com)
Cases1
M. avium is responsible for most cases of NTM lung infections worldwide [ 3 , 4 ]. (panafrican-med-journal.com)
Members1
General Information: They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. (up.ac.za)