• adduct
  • Ethionamide is a prodrug which is activated by the enzyme ethA, a mono-oxygenase in Mycobacterium tuberculosis, and then binds NAD+ to form an adduct which inhibits InhA in the same way as isoniazid. (wikipedia.org)
  • sodium
  • Budesonide Epinephrine (adrenaline) Salbutamol (albuterol) Oral rehydration salts Potassium chloride Glucose Glucose with sodium chloride Potassium chloride Sodium chloride Sodium hydrogen carbonate Sodium lactate, compound solution Water for injection Ascorbic acid Cholecalciferol Iodine Pyridoxine Retinol Riboflavin Sodium fluoride Thiamine Calcium gluconateα Acetic acid Budesonide Ciprofloxacin Xylometazoline Caffeine citrate Chlorhexidine Ibuprofenα Prostaglandin EαProstaglandin E1 Prostaglandin E2 Surfactantα No listings in this section. (wikipedia.org)
  • patients
  • Prophylaxis against opportunistic illnesses consisted of cotrimoxazole for patients with CD4 counts less than 200 cells/mm 3 and isoniazid/pyridoxine for all patients. (ucsf.edu)
  • When it happens, isoniazid-induced liver toxicity has been shown to occur in 50% of patients within the first 2 months of therapy. (wikipedia.org)
  • Liver toxicity occurs in up to 5% of patients and follows a pattern similar to isoniazid, usually arising in the first 1 to 3 months of therapy, but can occur even after more than 6 months of therapy. (wikipedia.org)
  • thought
  • Isoniazid is thought to induce a liver enzyme which causes a larger amount of acetaminophen to be metabolized to a toxic form. (wikipedia.org)
  • similar
  • While working in a similar manner to isoniazid, cross resistance is only seen in 13% of strains, since they are both prodrugs but activated by different pathways. (wikipedia.org)
  • further
  • Absorbed pyridoxamine is converted to PMP by pyridoxal kinase, which is further converted to PLP by pyridoxamine-phosphate transaminase or pyridoxine 5′-phosphate oxidase which also catalyzes the conversion of PNP to PLP. (wikipedia.org)