• They are ANTIPORTERS that exchange vesicular PROTONS for cytoplasmic NEUROTRANSMITTER and play an essential role in regulating neurotransmission. (uams.edu)
  • Proton pump releases more protons into the stomach, thereby increasing the secretion of acid. (drugbank.com)
  • Sodium-hydrogen exchangers (Na + /H + exchangers, NHE) are ATP-independent membrane glycoprotein transporters that are involved in the regulation of intracellular pH, cell volume and the cellular response to hormones and mitogens. (tocris.com)
  • The membrane pump is primarily responsible for maintaining homeostasis of pH and sodium. (wikipedia.org)
  • In one study, transgenic mice over expressing this membrane protein were shown to have increased reabsorption and retention of sodium after increased salt intake. (wikipedia.org)
  • The transporters mediate the simultaneous efflux of a hydrogen ion and the influx of a sodium ion across the plasma membrane, the driving force being the inwardly directed electrochemical Na + gradient. (tocris.com)
  • The proton pump activity of dR achieves a maximum effect by green light when dR is expressed in the Escherichia coli ( E. Coli ) membrane 8 . (nature.com)
  • Upon release, histamine acts on H 2 receptors expressed on the basolateral membrane of parietal cells, leading to increased intracellular cAMP levels and activated proton pumps on parietal cells. (drugbank.com)
  • H + antiporters of the CPA2 family (TC #2.A.37) to establish homology (K. Studley and M.H. Saier, Jr., unpublished results). (tcdb.org)
  • The enzyme transfers CO 2 from glutaconyl-CoA to a biotin carrier protein (the γ-subunit) that is subsequently decarboxylated by the carboxybiotin decarboxylation site within the Na + pumping beta subunit (Gcdβ). (tcdb.org)
  • Gemperli, A. C., Dimroth, P. & Steuber, J. Sodium ion cycling mediates energy coupling between complex I and ATP synthase. (uzh.ch)
  • La acción de tales antiportadores influye en el pH intracelular y en la homeostasis de los iones potasio. (bvsalud.org)
  • 1997). Sequence of a gene cluster from Malonomonas rubra encoding components of the malonate decarboxylase Na + pump and evidence for their function. (tcdb.org)
  • Loss of tubular function prevents the kidneys from excreting hydrogen cations (H + ) and thereby causes metabolic acidosis. (medscape.com)
  • Loss of tubular function prevents the kidneys from excreting hydrogen cations (H+) and thereby causes metabolic acidosis. (medscape.com)
  • Prospective studies involving very low birth weight (VLBW) infants (BW ≤1500 g) and extremely low birth weight (ELBW) infants (BW ≤1000 g) demonstrated a consistent pattern of fluid and sodium balance despite varying intakes of sodium and water over the first five to seven days of life [ 3,4 ]. (medilib.ir)