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  • vascular
  • We hypothesized that pulmonary arterial smooth muscle (PASMC) and endothelial cells (PAEC) may actively contribute to remodeling of the proximal pulmonary vascular wall in CTEPH. (semanticscholar.org)
  • Finally, these data suggest that in future drug trials in pulmonary vascular disease we need to be collecting genomic and transcriptomic data at a minimum at trial entry to potentially match patients with a strong effect size to genomic or transcriptomic patterns that can be used clinically or to better design future trials. (acc.org)
  • molecular
  • This suggests that we can move from a phenotypic classification to a molecular classification of pulmonary hypertension one day. (acc.org)
  • I would add that it's also possible that we can use the same methodology to identify molecular characteristics of non-Group 1 pulmonary hypertension. (acc.org)
  • The end result of these efforts will be, ideally, a better molecular understanding of pulmonary hypertension and better care for this hetereogeneous yet all to commonly devastating condition. (acc.org)
  • Study
  • Our study will provide an updated picture of the clinical course of a more broadly defined scope of pulmonary hypertension and the effects of current therapy on survival, enabling the collection of data on demographics, clinical course, treatments, and outcomes. (clinicaltrials.gov)
  • vein
  • The pulmonary vein returns oxygenated blood to the left atrium of the heart. (wikipedia.org)
  • citation needed] The symptoms/signs of pulmonary heart disease (cor pulmonale) can be non-specific and depend on the stage of the disorder, and can include blood backing up into the systemic venous system, including the hepatic vein. (wikipedia.org)
  • vasculature
  • MRI has clear advantages over echocardiography for accurate definition of right heart function and structure and to derive functional information regarding the pulmonary vasculature. (lu.se)
  • pulmonale
  • Pulmonary heart disease (cor pulmonale) Right heart failure The apical-four-chamber (A4C) view is best to visualize right heart strain by echo. (wikipedia.org)
  • The epidemiology of pulmonary heart disease (cor pulmonale) accounts for 7% of all heart disease in the U.S. According to Weitzenblum, et al. (wikipedia.org)
  • vascular
  • We hypothesized that pulmonary arterial smooth muscle (PASMC) and endothelial cells (PAEC) may actively contribute to remodeling of the proximal pulmonary vascular wall in CTEPH. (semanticscholar.org)
  • Finally, these data suggest that in future drug trials in pulmonary vascular disease we need to be collecting genomic and transcriptomic data at a minimum at trial entry to potentially match patients with a strong effect size to genomic or transcriptomic patterns that can be used clinically or to better design future trials. (acc.org)
  • molecular
  • This suggests that we can move from a phenotypic classification to a molecular classification of pulmonary hypertension one day. (acc.org)
  • I would add that it's also possible that we can use the same methodology to identify molecular characteristics of non-Group 1 pulmonary hypertension. (acc.org)
  • The end result of these efforts will be, ideally, a better molecular understanding of pulmonary hypertension and better care for this hetereogeneous yet all to commonly devastating condition. (acc.org)
  • Study
  • Our study will provide an updated picture of the clinical course of a more broadly defined scope of pulmonary hypertension and the effects of current therapy on survival, enabling the collection of data on demographics, clinical course, treatments, and outcomes. (clinicaltrials.gov)
  • artery
  • He is also notable for saving many lives by pioneering a technique for 'switching' the heart vessels of babies born with transposition of the great arteries, a congenital heart defect in which the two major vessels carrying blood out of the heart, the aorta and the pulmonary artery, are switched. (wikipedia.org)
  • In the hybrid procedure, bilateral pulmonary artery bands are positioned to limit pulmonary flow while, at the same time, placing a stent in the ductus arteriosus to hold it open. (wikipedia.org)
  • Yu performed pioneering research in cardiac physiology, making seminal observations about the pulmonary circulation in health and disease, and the relationship to ventricular function, and key observations about the care of patients with coronary artery disease. (wikipedia.org)
  • Congestive
  • 427.8) Other specified cardiac dysrhythmias (427.81) Sick sinus syndrome (427.89) Sinus bradycardia, NOS (427.9) Cardiac dysrhythmia unspecified Gallop rhythm (428) Heart failure (428.0) Congestive heart failure unspecified (428.1) Left heart failure Pulmonary edema, acute (428.2) Systolic heart failure (428.3) Diastolic heart failure (428.4) Heart failure, combined, unspec. (wikipedia.org)
  • chronic
  • When the blood contains inadequate amounts of A1AT or functionally defective A1AT (such as in alpha-1 antitrypsin deficiency), neutrophil elastase is excessively free to break down elastin, degrading the elasticity of the lungs, which results in respiratory complications, such as chronic obstructive pulmonary disease, in adults. (wikipedia.org)
  • textbook
  • Yu served on the editorial boards of the American Heart Journal, Circulation and the Journal of Electrocardiology and was a senior editor of Modern Concepts of Cardiovascular Disease, co-editor of the 16-volume Progress in Cardiology and author of the textbook Pulmonary Blood Volume in Health and Disease. (wikipedia.org)
  • flows
  • Using the recognized physiologic definitions of flows and shunts the transposition circulation is characterized by a diminished effective flow and a bidirectional but predominantly left-to-right shunt. (ahajournals.org)
  • A system of differential equations for concentration or quantity of substance on each compartment can be written, and its parameters represent blood flows, pulmonary ventilation rate, organ volumes etc., for which information is available in scientific publications. (wikipedia.org)
  • severe
  • Intravenous sodium bicarbonate is indicated in the treatment of metabolic acidosis, such as can occur in severe kidney disease, diabetic ketoacidosis, circulatory insufficiency, extracorporeal circulation of blood, in hemolysis requiring alkalinization of the urine to avoid nephrotoxicity of blood pigments, and certain drug intoxications, such as by barbiturate overdose, salicylate poisoning, tricyclic antidepressant overdose or methanol poisoning. (wikipedia.org)
  • days
  • He encouraged nature very always, and gave approach and rigid days improperly when the circulation was generally immediate. (tilakpyle.com)