• It appears as an elevated yellow-white plaque in the bulbar conjunctiva near the limbus. (wikipedia.org)
  • Human primary nasal pterygia and normal superotemporal bulbar conjunctival tissue of the same eye were collected in the context of conventional excision of pterygium with autotransplantation of conjunctiva. (arvojournals.org)
  • A pterygium is a fleshy triangular growth of bulbar conjunctiva, occurring only at the 3 and 9 o'clock meridians of either eye, usually not simultaneously. (msdmanuals.com)
  • Pterygium is a triangular fold of bulbar conjunctiva usually found in the nasal side of the interpalpebral fissure. (bijojournal.org)
  • Forms the junction between the bulbar and palpebral conjunctivas: It is loose and flexible, allowing the free movement of the lids and eyeball. (wikipedia.org)
  • Blood to the bulbar conjunctiva is primarily derived from the ophthalmic artery. (wikipedia.org)
  • However, the circulations of the bulbar conjunctiva and palpebral conjunctiva are linked, so both bulbar conjunctival and palpebral conjunctival vessels are supplied by both the ophthalmic artery and the external carotid artery, to varying extents. (wikipedia.org)
  • Pinguecula (Latin, pingueculus , meaning fatty) is a common degenerative lesion of the bulbar conjunctiva, also arising in the horizontal meridian. (mhmedical.com)
  • Tissue samples were collected from primary pterygia, recurrent pterygia, and normal conjunctiva to perform the following experiments: immunohistochemical measurement of IPO13 and K17. (molvis.org)
  • During surgery, the doctor anesthetizes the eye and extracts the pterygium and eye tissue covering the conjunctiva. (lasereyecenter.com)
  • A pterygium is a noncancerous growth that starts in the clear, thin tissue ( conjunctiva ) of the eye. (medlineplus.gov)
  • Pterygium is a non-malignant, slow-growing conjunctival fibrous vascular tissue of the conjunctiva. (researchsquare.com)
  • The loose connective tissue under the epithelium contains a large number of fibroblasts and abundant capillaries, which indicates that the pterygium epithelial cells have a strong ability to proliferate and migrate. (researchsquare.com)
  • 0.05, false discovery rate 20%) distinguished primary pterygium from normal conjunctival tissue. (arvojournals.org)
  • In this Surgery, removal of limbal tissue and adjacent conjunctiva is done with pterygium. (solelyverified.in)
  • Pterygia are nourished by tiny capillaries that supply blood to the tissue. (visioneyes.co.za)
  • Removal of the abnormal pterygium tissue and covering the bare sclera with patient's own conjunctiva is the standard surgical procedure (conjunctival autograft). (eyecarenayonika.com)
  • In this method, ailing tissues are completely removed and the area remained as empty are covered by a healthy membrane pieces or namely by a normal conjunctiva tissue. (drhuseyinacar.com)
  • Ailing tissue is removed under local anaesthesia and instead healthy conjunctiva tissue is inserted into this area. (drhuseyinacar.com)
  • Pterygium (Greek, pterygion , meaning wing-like) is a benign proliferation of fibrovascular tissue. (mhmedical.com)
  • Here we investigated the role of IPO13 in the pathogenesis of pterygium and the underlying mechanism including interaction with other cell proliferation-related factors: keratin 17 (K17), a lesional protein and a member of the type I keratins, and c-Jun, a protein of the activator protein-1 complex. (molvis.org)
  • We provided novel evidence that IPO13 may contribute to the pathogenesis of pterygium via modulation of K17 and c-Jun. (molvis.org)
  • The pathogenesis and mechanism of the pterygium remain largely unknown. (molvis.org)
  • Coroneo MT, Di Girolamo N, Wakefield D. The pathogenesis of pterygia. (medscape.com)
  • This study is the first to identify a combined miRNA and mRNA gene expression profile of human primary pterygium, which may contribute to the understanding of pterygium pathogenesis. (arvojournals.org)
  • Because the antitumor activities of supplement D are mediated through the nuclear supplement D receptor (VDR) mainly, the purpose of today's study was to research supplement D position in individuals with pterygium and in charge topics, and VDR immunohistochemical manifestation in examples of pterygium and regular conjunctiva to be Birinapant inhibitor able to assess a possible function of supplement D pathway in the pathogenesis of the condition. (bibf1120.com)
  • Although its pathogenesis appears multi-factorial, chronic irritation, angiogenesis and uncontrolled proliferation possess a key function in the pathogenesis of pterygium. (bibf1120.com)
  • According to the American Academy of Ophthalmology, the pterygium recurrence rate is between 30 and 40 percent, and more likely to occur in people under the age of 40. (lasereyecenter.com)
  • It then becomes necessary to remove the pterygium surgically. (lasereyecenter.com)
  • A pterygium can be removed surgically if it causes discomfort or distorts vision (by inducing astigmatism). (yeseyespecialists.com)
  • It involves surgically removing the eye and transplanting some of the conjunctivae from the upper portion of the eye to the removal area as a part of the treatment procedure. (harleyvision.com)
  • Starck T, Kenyon KR, Serrano F. Conjunctival autograft for primary and recurrent pterygia: surgical technique and problem management. (medscape.com)
  • Fixation of conjunctival autograft using autologous blood in pterygium surgery is a safe and economical method. (sjopthal.net)
  • The technique with the best results to prevent recurrence is surgical removal of the pterygium followed by conjunctival autograft. (msdmanuals.com)
  • Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft. (medscape.com)
  • Before, and 10 days, 1 month, 3 months, and 6 months after surgery, the tear film rupture time (BUT), the height of the tear river (SLT), and the anterior segment of the fluoroscopy staining were recorded to record the scar on the conjunctiva and corneal surface. (researchsquare.com)
  • A pterygium is an elevated, superficial, external ocular mass that usually forms over the perilimbal conjunctiva and extends onto the corneal surface. (medscape.com)
  • During this period, a visual acuity test is done to check the possibilities of astigmatism caused by the invasion of the fleshy pterygium over the corneal surface. (harleyvision.com)
  • Many pterygia start as pingueculae. (healthline.com)
  • Elevated lesions of the conjunctiva such as pingueculae and pterygia oftentimes present challenges in fitting the patient desiring refractive correction with contact lenses. (odsonfb.com)
  • Pterygia and pingueculae are found on the horizontal meridian. (mhmedical.com)
  • Bumps on the eyeball are typically growths of the conjunctiva, a clear ocular membrane that covers the white part of the eye. (healthline.com)
  • Pterygium is one of the most common ocular surface diseases. (molvis.org)
  • Patients who are at high risk of the development of pterygium because of a positive family history of pterygia or because of extended exposure to ultraviolet irradiation need to be educated in the use of ultraviolet-blocking glasses and other means of reducing ocular exposure to ultraviolet light. (medscape.com)
  • Загальні відомості про захворювання кон'юнктиви та склери The conjunctiva lines the back of the eyelids (palpebral or tarsal conjunctiva), crosses the space between the lid and the globe (forniceal conjunctiva), then folds back on itself as it spreads. (msdmanuals.com)
  • Pterygia can develop on the nasal and/or temporal limbus and can affect either or both eyes. (medscape.com)
  • It usually originates in the nasal conjunctiva on the horizontal meridian of the limbus. (mhmedical.com)
  • Pterygia are more likely than pinguecula to be found on the nasal conjunctiva and bilateral. (mhmedical.com)
  • Larger growths on the conjunctiva - the clear membrane that covers the eye - may also be a tumor, especially if the bump has grown significantly over time. (healthline.com)
  • Pinguecula and pterygium are conjunctival growths that may result from chronic actinic irritation. (msdmanuals.com)
  • Growths inside the eyeball on the conjunctiva called pterygiums are linked to consistent UV exposure. (boptom.com)
  • Pterygium epithelial cells (PECs) were cultured in keratinocyte serum-free defined medium to examine the expression of IPO13 and K17. (molvis.org)
  • Though the exact reason is not known, it is postulated by researchers and scientists that pterygium occurs due to hyperplasticity or excess growth of the limbal epithelial cells along with vascularization or formation of blood vessels over it that gives it its pink appearance. (harleyvision.com)
  • In conjunctiva, the immunoreactivity, localized in cytoplasm of epithelial cells generally, may demonstrate VDR legislation of cell development most likely, differentiation, and apoptosis, while in pterygium VDR co-localization in the nucleus and cytoplasm of epithelial cells may suggest choice nuclear pathways where supplement D might exert its antiinflammatory and anti-proliferative results by the legislation of gene appearance. (bibf1120.com)
  • Pterygium excision combined with autologous conjunctival flap transposition, pterygium excision combined with amniotic membrane transplantation, pterygium excision combined with autologous limbal stem cell transplantation and so on [12] . (researchsquare.com)
  • Those patients who develop recurrent pterygia can be retreated with repeat surgical excision and grafting, with conjunctival/limbal autografts or amniotic membrane transplants in selected patients. (medscape.com)
  • Sclera is covered by a transparent membrane, called conjunctiva . (eyecarenayonika.com)
  • This membrane layer is called as conjunctiva. (drhuseyinacar.com)
  • A pterygium is a growth on the conjunctiva, which is the delicate membrane covering the white area of the eye (the sclera). (sceyes.org)
  • Jain AK, Bansal R, Sukhija J. Human amniotic membrane transplantation with fibrin glue in management of primary pterygia: a new tuck-in technique. (medscape.com)
  • Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium. (medscape.com)
  • Oguz H. Amniotic membrane grafting versus conjunctival autografting in pterygium surgery. (medscape.com)
  • The postoperative follow-up period (6 months), the recurrence rate of pterygium was 0.21%.Patients have higher satisfaction with appearance, and have no obvious foreign body sensation, photophobia, tearing and other subjective symptoms. (researchsquare.com)
  • Discussion and conclusion Extensive fascial resection combined with autologous limbal stem cell sharing transplantation for the treatment of pterygium, the patient's appearance satisfaction is higher, and the recurrence probability is lower than the average recurrence rate of limbal stem cell transplantation. (researchsquare.com)
  • Surgical excision is the main treatment of pterygium, but the postoperative recurrence rate is high, the appearance of the eye is not ideal, postoperative foreign body feeling has been a difficult problem of clinical treatment. (researchsquare.com)
  • Therefore, we conducted an updated meta-analysis to further explore the association between FG application in pterygium surgery, and the recurrence rate, complication rate, and surgical duration. (oncotarget.com)
  • Although there was no difference in complication rate between FG and sutures, the apparent advantages of FG over sutures are shorter surgical duration and greater reduction in the recurrence rate of pterygium. (oncotarget.com)
  • The standard treatment for pterygium is surgical excision, but the recurrence rate after surgery can be as high as 24%-89%, which compromises outcomes [ 4 ]. (oncotarget.com)
  • During the past decade, the debate over the best approach to pterygium surgery has centered on whether surgeons should use sutures or fibrin glue to affix the conjunctival graft. (aao.org)
  • Outcome of pterygium surgery: analysis over 14 years. (medscape.com)
  • Eye rubbing causing conjunctival graft dehiscence following pterygium surgery with fibrin glue. (medscape.com)
  • Pterygium surgery with mitomycin-C: ten-year results. (medscape.com)
  • Treatment of pterygium disorder is performed by surgery. (drhuseyinacar.com)
  • Surgery is only recommended if the risk of corneal scarring and vision loss due to the progression of the pterygium is high. (harleyvision.com)
  • Efficacy of fibrin glue versus sutures for attaching conjunctival autografts in pterygium surgery: a systematic review with meta-analysis and trial. (oncotarget.com)
  • Bahar I, Weinberger D, Gaton DD, Avisar R. Fibrin glue versus vicryl sutures for primary conjunctival closure in pterygium surgery: long-term results. (medscape.com)
  • The appearances of solar keratosis, pinguecula, and pterygium are presented as part of a continuous spectrum of the same pathological process and aetiology, which may lead to carcinomatous change. (bmj.com)
  • Pinguecula and pterygium. (medlineplus.gov)
  • Sunglasses indeed reduce the risk of developing non-cancerous growth of pinguecula and pterygium. (sojosvision.com)
  • The causes of both pinguecula and pterygium are excessive exposure to UV rays alongside dry eyes and exposure to surrounding environmental factors which can irritate the eyes. (bumrungrad.com)
  • Generally, pinguecula and pterygium are able to be diagnosed through a simple visual observation. (bumrungrad.com)
  • For both pinguecula and pterygium, if the condition is not too severe, patients may only notice a growth on the eye. (bumrungrad.com)
  • Decreased visual acuity may result as the pterygium encroaches on the visual axis or if the lesion induces astigmatism. (mhmedical.com)
  • Surgical excision by the ophthalmologist is indicated if the pterygium interferes with contact lens wear, encroaches significantly on the visual axis resulting in induced astigmatism or opacity, or restricts eye movement. (mhmedical.com)
  • Most pterygia cause no problems and do not need surgical treatment. (medlineplus.gov)
  • At present, there are many surgical methods for pterygium, including simple pterygium excision. (researchsquare.com)
  • This study aimed to study the efficacy and surgical outcome of using autologous blood for conjunctival autografting in pterygium excision. (sjopthal.net)
  • Following surgical excision, recurrence of pterygia is common. (mhmedical.com)
  • The purpose of the study was to study the regulatory mechanisms mediated by miRNAs and their importance in human primary pterygium. (arvojournals.org)
  • A total of 100 patients have primary pterygium in one eye (unilateral) compared to their healthy (control) eye. (bijojournal.org)
  • This is also sometimes known as "surfer's eye" or "farmers eye" because being exposed to harmful UV rays for long hours can increase your risk of getting a pterygium. (healthline.com)
  • Since surfers are frequently exposed to these elements, pterygium developed the nickname "surfer's eye. (lasereyecenter.com)
  • This region of the conjunctiva is tightly bound to the underlying sclera by Tenon's capsule and moves with the eyeball movements. (wikipedia.org)
  • With age, the conjunctiva can stretch and loosen from the underlying sclera, leading to the formation of conjunctival folds, a condition known as conjunctivochalasis . (wikipedia.org)
  • As a matter of fact, many writers2,3 showed that preneoplastic lesions could be connected with pterygium. (bibf1120.com)
  • These lesions can slowly evolve over the years, waxing and waning, extending radially over larger areas of conjunctiva and skin. (medscape.com)
  • Malignant melanomas arising from nevi (they may arise from junctional and compound nevi) usually appear as a change (increasing nodularity, variegated pigmentation, bleeding, or inflammation) in known pigmented lesions of the conjunctiva. (medscape.com)
  • The blood supply to the palpebral conjunctiva (the eyelid) is derived from the external carotid artery . (wikipedia.org)
  • Pterygium is noncancerous but may cause eye irritation, discoloration, and excessive tearing. (lasereyecenter.com)
  • The exact cause of pterygium is not well understood, but long-term exposure to sunlight, especially ultraviolet rays, wind, and chronic eye irritation from dry and dusty conditions seems to play an important causal role. (bijojournal.org)
  • Pterygia may be asymptomatic or become inflamed, causing mild symptoms of irritation and foreign-body sensation. (mhmedical.com)
  • It is believed that pterygium is caused by ultraviolet (UV) light from the sun, as well as excessive exposure to wind and dirt. (lasereyecenter.com)
  • Patients with pterygium should reduce exposure to ultraviolet light whenever possible. (medscape.com)
  • Threlfall TJ, English DR. Sun exposure and pterygium of the eye: a dose-response curve. (medscape.com)
  • Since pterygia are most commonly caused by sun exposure, protecting the eyes from sun, dust and wind is recommended. (visioneyes.co.za)
  • Exposure to the sun can lead to inflammation of the already inflamed pterygium and worsen the dryness and grittiness symptoms. (harleyvision.com)
  • The exact cause of a pterygium is not known, although significant exposure to sunlight and ultraviolet (UV) rays are suspected factors. (sceyes.org)
  • Uy HS, Reyes JM, Flores JD, Lim-Bon-Siong R. Comparison of fibrin glue and sutures for attaching conjunctival autografts after pterygium excision. (medscape.com)
  • The six most common eye diseases pterygium, glaucoma, cataracts, diabetic retinopathy, floaters, and age-related macular degeneration are worth understanding to protect your eye health. (woomlo.com)
  • 16,20-24 For a long period many authors have got labelled pterygium being a chronic degenerative development disorder, but, following breakthrough of p53 overexpression in the epithelium,15,25-28 it really is regarded as an UV-related tumor now. (bibf1120.com)
  • The simplest and least invasive pterygium treatment is lubricating eye drops, ointments or mild steroid eye drops to reduce inflammation. (lasereyecenter.com)
  • Use of Non-Steroidal-Anti-Inflammatory-Drugs ( NSAIDs), i.e., a group of medications with anti-inflammatory effects minus the side effects of steroids, is highly recommended in pterygium patients for long-term use of reducing the inflammation. (harleyvision.com)
  • Patients older than 40 years have the highest prevalence of pterygia, while patients aged 20-40 years are reported to have the highest incidence of pterygium. (medscape.com)
  • Saw SM, Tan D. Pterygium: prevalence, demography and risk factors. (medscape.com)
  • Introduction To observe the short-term and long-term effects of extensive fascial resection combined with autologous limbal stem cell sharing transplantation for pterygium. (researchsquare.com)
  • It is uncommon for patients to present with pterygium prior to age 20 years. (medscape.com)
  • A prospective, interventional hospital-based study was carried out over 17 eyes of 17 patients having primary or recurrent pterygium. (sjopthal.net)
  • Pterygium excision followed by conjunctiva autografting was performed in all the patients. (sjopthal.net)
  • Unfortunately, the chance of recurrence is high for pinguecula or pterygium, especially in younger patients or patients who overexpose themselves to UV light. (bumrungrad.com)
  • Les patients qui ont accepté de participer après apptéléphonique ont été inclus de janvier à mai 2021.Les variables d'étudeétaient: âge, sexe, acuité visuelle (AV), caractéristiques de la LCET selon Diallo, pronostic fonctionnel et anatomique en post puberté (plus de 15 ans). (bvsalud.org)
  • IPO13 activity was significantly increased in the basal layer of the epithelium of the pterygium. (molvis.org)
  • IPO13 was colocalized with K17 in the epithelium of the pterygium, and overexpression or knockdown of the IPO13 gene induced upregulation or downregulation of K17 expression in PECs, respectively. (molvis.org)
  • The pathophysiology of pterygium is characterized by elastotic degeneration of collagen and fibrovascular proliferation, with an overlying covering of epithelium. (medscape.com)
  • The conjunctiva consists of unkeratinized, both stratified squamous and stratified columnar epithelium, with interspersed goblet cells . (wikipedia.org)
  • Together with mucus-secreting goblet cells within the stratified epithelium, melanocytic cells are found in the basal layer of the conjunctiva. (medscape.com)