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  • Dermatology
  • UV-A therapy was found to be more effective than narrowband UV-B therapy in treating patients with chronic plaque psoriasis, according to an article in the July issue of Archives of Dermatology. (rxpgnews.com)
  • Increased levels of estrogen that occur during pregnancy may be associated with improvement in psoriasis, according to a study in the May issue of the Archives of Dermatology, one of the JAMA/Archives journals. (rxpgnews.com)
  • An article published in Pediatric Dermatology said, "The GPP pattern is as an acute, episodic, and potentially life-threatening form of psoriasis. (wikipedia.org)
  • To address the shortage of clinicians with in-depth knowledge of psoriatic disease, the National Psoriasis Foundation awards annual Medical Dermatology Fellowships. (wikipedia.org)
  • triggers
  • When psoriasis triggers T cells to attack healthy skin, the immune system responds by sending more blood to the area and making more skin cells and more white blood cells. (kidshealth.org)
  • mild psoriasis
  • Combination of calcipotriene and betamethasone ointment - In a 4 week trial of patients with mild to severe plaque psoriasis - 48% of patients treated with the combination agent achieved absent or mild psoriasis, compared to 16.5% of patients treated with calcipotriene once daily, 26.3% of patients treated with betamethasone once daily, and 7.6% of patients treated with placebo. (aad.org)
  • torso
  • Napkin psoriasis is a subtype of psoriasis common in infants characterized by red papules with silver scale in the diaper area that may extend to the torso or limbs. (wikipedia.org)
  • itchy
  • Sometimes psoriasis can be hidden by wearing long pants and sleeves, but it can be difficult to hide, especially if the patches become painful and itchy. (healthcentral.com)
  • Zumbusch
  • Sometimes all or any of GPP is referred to as von Zumbusch psoriasis, but in the literature it is often distinguished as one specific form of GPP. (wikipedia.org)
  • clinical
  • The App is based on the AAD psoriasis clinical guidelines. (aad.org)
  • Although Hippocrates described scaling diseases of the skin under heading 'lopoi', the first clinical description of psoriasis is attributed to Aurelius Celsus who mentioned this disease in his work De re medica . (news-medical.net)
  • A complex interplay between genetic factors and immunology culminates in the specific clinical and histological features of psoriasis. (news-medical.net)
  • The 'National Psoriasis Victor Henschel BioBank is a collection of biological samples and clinical information used by qualified scientists to advance the field of psoriasis genetics. (wikipedia.org)
  • treatments
  • The National Psoriasis Foundation works to increase the number of dollars, scientists and quality research projects devoted to psoriatic disease to find better treatments and a cure. (wikipedia.org)
  • The National Psoriasis Foundation focuses on changing policy to increase the federal government's attention on psoriatic disease, and to ensure that people get access to the treatments and medical specialists they need to best manage their condition. (wikipedia.org)
  • patients
  • So, they looked for antibodies to that particular dUTPase in psoriasis patients, and healthy controls. (scienceblogs.com)
  • On average, the psoriasis patients had more antibodies to this ERV dUTPase than the controls! (scienceblogs.com)
  • And, some psoriasis patients had the same levels of dUTPase antibodies as healthy people, and some healthy people had the same levels of dUTPase antibodies as the psoriasis patients. (scienceblogs.com)
  • The psoriasis patients had CTL responses to dUTPase, while the healthy controls did not. (scienceblogs.com)
  • After looking at the HERV K dUTPase gene in 708 patients and 349 controls, there were 14 single nucleotide polymorphisms (tiny changes) is psoriasis patients and not the controls. (scienceblogs.com)
  • What about psoriasis patients' antibodies and TCL response to other ERV proteins, relative to controls. (scienceblogs.com)
  • An alternate explanation would be that psoriasis patients have disordered immune systems for reasons unrelated to the dUTPase but that the the results weakly measure the fact that they have disordered immune systems. (scienceblogs.com)
  • Likewise, psoriasis patients with ERV gene sequences more closely related to one another than the general population could mean that the ERV genes have something to do with psoriasis. (scienceblogs.com)
  • If psoriasis patients show association with reaction to/sequence of one or a few ERV genes/proteins, that would imply that the ERV genes are being expressed and doing something. (scienceblogs.com)
  • On the other hand, if psoriasis patients have indiscriminate exaggerated antibody/CTL response to vast numbers of ERV proteins, that might imply that the reactions are secondary to whatever is really going on in psoriasis, and that the genetic pattern reflects linkage of some ERV genes to whatever genes really matter, or psoriasis patients sharing recent common ancestry due to a local bottleneck. (scienceblogs.com)
  • Drug maker Hoffman-LaRoche acknowledged this and other side effects but said during seven years of testing, patients preferred to live with the stiffness in exchange for alleviation of the psoriasis. (orlandosentinel.com)
  • reported that in GPP patients ten or younger, less than 12% of cases are preceded by ordinary psoriasis. (wikipedia.org)
  • The Psoriasis Index of Quality of Life (PSORIQoL) is a patient-reported outcome measure which determines the quality of life of patients with psoriasis. (wikipedia.org)
  • The content of the PSORIQOL was derived from 62 qualitative interviews with psoriasis patients. (wikipedia.org)
  • The PSORIQoL was then completed by two new samples of psoriasis patients by mail, in order to confirm validity and reliability. (wikipedia.org)
  • genes
  • Or that psoriasis has a genetic component, but that the ERV gene distribution in question is merely linked with whatever the real genes that actually matter are. (scienceblogs.com)
  • Research studies have shown many different genes are linked to the development of psoriasis. (www.nhs.uk)
  • immune
  • This project will evaluate whether the presence of a protein, called Stim1, in blood immune cells modifies differently the immune response between a person with psoriasis, a person with a chronic inflammatory disease, and a healthy person. (nih.gov)
  • Be part of a research project to help scientists at NIEHS understand the immune response differences between in those with psoriasis, a chronic inflammatory disease, or who are healthy. (nih.gov)
  • Maybe its not antibodies, but cellular immune responses to an ERV protein that are causing psoriasis! (scienceblogs.com)