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  • glutamate
  • 1 In this article, the authors reported the approach of examining glutamate/glutamine peaks in 1 H-MR (proton) spectroscopy to increase the specificity in differentiating tumefactive demyelinating processes from neoplasms. (ajnr.org)
  • Although we commend the authors' enthusiasm for this technique, the paper lacks statistical significance and contains much bias to support the authors' claim that MR spectroscopy "can be helpful in the noninvasive diagnosis of acute demyelinating diseases" 1 when elevated glutamate/glutamine peaks are identified. (ajnr.org)
  • Results: Changes in the N-acetylaspartate (NAA), choline (Cho), myo-inositol (MI), creatine (Cr) and glutamine/glutamate (Glx) resonances were quantified both in absolute terms and relative to the creatine resonance. (harvard.edu)
  • humans
  • Conclusion It is feasible to construct a double-quadrature 13C-1H surface coil for proton decoupled sensitivity enhanced 13C-NMR spectroscopy in humans at 7T. (epfl.ch)
  • GABA function can also be investigated indirectly in humans through the use of non-invasive transcranial magnetic stimulation (TMS) techniques that can be used to measure cortical excitability and GABA-mediated physiological inhibition. (ox.ac.uk)
  • Although proton magnetic resonance spectroscopy (1H-MRS) has been used with success to quantify vertebral MAT in humans, it is difficult to employ in laboratory animals. (wikipedia.org)
  • ratio
  • Moreover, our results strongly indicate that the resonance ratio of inositol (at 4.05 ppm) to creatine may help distinguish tumor type. (aacrjournals.org)
  • The signal-to-noise ratio (SNR) was measured on the glycogen and glucose resonances by 13C-MRS in vitro, compared with that obtained with a linear-13C/quadrature-1H coil, and validated by 13C-MRS in vivo in the human calf at 7T. (epfl.ch)
  • frequency
  • Purpose Carbon-13 magnetic resonance spectroscopy (13C-MRS) is challenging because of the inherent low sensitivity of 13C detection and the need for radiofrequency transmission at the 1H frequency while receiving the 13C signal, the latter requiring electrical decoupling of the 13C and 1H radiofrequency channels. (epfl.ch)
  • The values in the phase images are constrained from -π to π so if the value goes above π it wraps to -π, inhomogeneities in the magnetic field cause low frequency background gradients. (wikipedia.org)
  • known
  • He was known for his studies on quantum-mechanical interpretation of magnetic resonance data and his contributions in developing IIT Kanpur into a Centre of Excellence in academic research in basic sciences. (wikipedia.org)
  • medical
  • Magnetic resonance spectroscopy (MRS) is a non-invasive and non-ionizing technique that is well described in the human medical literature and is most frequently used to evaluate the metabolic activity of tissues with questionable malignant transformation. (illinois.edu)
  • research
  • According to the above research literature, the investigators considered further investigation of the proton MRS in evaluating the musculoskeletal system. (clinicaltrials.gov)
  • He organized an active research school at the Indian Institute of Technology, Kanpur featuring scholars from physics and chemistry departments which worked on the theoretical and experimental aspects of magnetic resonance. (wikipedia.org)
  • small
  • Single Voxel Spectroscopy (SVS): has a minimum spatial resolution of approximately 1 cm3, and has the cleanest spectrum free from unwanted artefacts due to the small acquired volume. (wikipedia.org)
  • Therefore
  • Therefore this paper is of limited scope, giving an overview of technical issues that are important to clinical proton MRS, discussing some common clinical MRS problems, and suggest- ing how they might be resolved. (aapm.org)
  • common
  • Some fundamental issues covered in this paper are common to many forms of magnetic resonance spectroscopy and are written as an introduction for the reader to these methods. (aapm.org)
  • The nucleus of deuterium, called a deuteron, contains one proton and one neutron, whereas the far more common protium has no neutron in the nucleus. (wikipedia.org)
  • field
  • These steps include: Shimming the magnetic field: this step is taken to correct for the inhomogeneity of the magnetic field by tuning different pulses in the x, y, and z directions. (wikipedia.org)
  • hydrogen
  • Because the muon is a lepton, the atomic energy levels of muonium can be calculated with great precision from quantum electrodynamics (QED), unlike in the case of hydrogen, where the precision is limited by uncertainties related to the internal structure of the proton. (wikipedia.org)
  • A collective switch of hydrogen bond orientations may contribute to the directionality of proton flux as His37 is dynamically protonated and deprotonated in the conduction cycle. (wikipedia.org)
  • spectroscopic
  • Here we applied non-invasive magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) of syngeneic mouse tumors in vivo , and high-resolution 1 H MRS of mouse tumor extracts, to characterize the relationship between ascites volumes and the vasculature and metabolism of an experimental model of ovarian cancer. (frontiersin.org)
  • Although this sp3 center disrupts the continuous overlap of p-orbitals, traditionally thought to be a requirement for aromaticity, considerable thermodynamic stability and many of the spectroscopic, magnetic, and chemical properties associated with aromatic compounds are still observed for such compounds. (wikipedia.org)
  • single
  • Moreover, protons diffusing through the channel need not be localized to a single His37 imidazole, but instead may be delocalized over the entire His-box and associated water clusters. (wikipedia.org)
  • shows
  • In the laboratory hexafluorobenzene is used as standard in fluorine-19 NMR spectroscopy, solvent and standard in carbon-13 NMR, solvent in proton NMR, solvent when studying some parts in the Infrared and solvent in Ultraviolet-visible spectroscopy, as hexafluorobenzene itself hardly shows any absorbance in the UV region. (wikipedia.org)
  • conditions
  • Gamma-aminobutyric acid (GABA) and glutamate are implicated in numerous neuropsychiatric and substance abuse conditions, but their spectral overlap with other resonances makes them a challenge to quantify in humans. (drugs.com)
  • origin
  • NYC SCA839882012-08-01T00:00:00Furniture download optimal transport theory for a Public SchoolThe Weeks Lerman889202013-01-01T00:00:00Furniture text of Office Furniture for three resonance origin of 12 stories for the Borough of Manhattan Community College. (kar-men.com)
  • activity
  • When His37 is replaced with glycine, alanine, glutamic acid, serine or threonine, the proton selective activity is lost and the mutant can transport Na+ and K+ ions also. (wikipedia.org)
  • positive
  • If an atom has more or fewer electrons than protons, then it has an overall negative or positive charge, respectively, and it is called an ion. (wikipedia.org)