• protein
  • This study investigates the frequency of vitamin K deficiency among a convenience sample of children and adults with cholestatic liver disease by determining plasma levels of protein induced in vitamin K absence II (PIVKA-II), and assesses the relationship between PIVKA-II levels and markers of cholestasis, measured prothrombin time, and vitamin A, E and 25-hydroxyvitamin D levels. (openthesis.org)
  • TF mRNA was analyzed by real-time polymerase chain reaction, and cellular and released TF protein antigen were analyzed by Western blot. (ahajournals.org)
  • Apixaban was added to plasma from healthy subjects in the concentration range 0-1000 μg L(-1) , and analyses were performed with different reagents for activated partial thromboplastin time (APTT), prothrombin time (PT), antithrombin, protein C, and protein S. A lupus anticoagulant assay and an APTT assay with varying phospholipid concentrations were used to study the phospholipid dependence. (diva-portal.org)
  • blood
  • All subjects had blood collected for liver function tests, prothrombin time (PT), INR, bile acids, 25-hydroxyvitamin D, vitamin A, vitamin E and PIVKA-II levels. (openthesis.org)
  • Tissue factor (TF) is a transmembrane cell surface glycoprotein of 45 to 50 kDa that forms a complex with activated factor VII, initiating blood coagulation and leading to the focal production of thrombin via the successive activation of factor IX, factor X, and prothrombin. (ahajournals.org)
  • Factor V Leiden (FVL) mutation and prothrombin 20210 (PT 20210) mutation tests are two tests often used together to help diagnose the cause of inappropriate blood clot (thrombus) formation, including deep vein thrombosis (DVT) and/or venous thromboembolism (VTE). (labtestsonline.org)
  • Factor V and prothrombin are two coagulation factors essential for proper blood clot formation. (labtestsonline.org)
  • People with two copies of the Factor V Leiden mutation (homozygous) may have up to 80 times the risk of developing a blood clot while those with one copy have 4 to 8 times the risk. (labtestsonline.org)