Caseous lymphadenitisStrainsDiphtheriaeSpeciesEquiBacteriaAcquired immunityFacultativeGenusPathogenicUlcerativeDomesticated sheep and goatsSheepCorynebacterialBacterium2022AnalysesGenesClinicalIsolationCitation neededHypothetical proteinOrganismVirulence factorsRespiratoryUrinaryPathogenesisIntestinalInfectiousHorsesVaccineResistanceAttemptsDiseaseDistinctSecondaryIsolatesAdditionUlcersStudyGroupHost
Caseous lymphadenitis4
- In small ruminants, C. pseudotuberculosis causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. (wikipedia.org)
- citation needed] Distribution of C. pseudotuberculosis is mostly traced by examining prevalence of caseous lymphadenitis, the bacterium's main pathological disease. (wikipedia.org)
- Hence, we sought to implement a combined approach for characterizing the entire exoproteome of the pathogenic bacterium Corynebacterium pseudotuberculosis , the etiological agent of caseous lymphadenitis (CLA) in sheep and goats. (biomedcentral.com)
- This study set out to sequence the genome of Corynebacterium pseudotuberculosis (Cp) 3/99-5, an ovine strain isolated from a naturally-occurring case of caseous lymphadenitis (CLA) in Scotland. (gla.ac.uk)
Strains6
- 44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
- Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
- Diphtheria is an infectious disease caused by toxigenic strains of Corynebacterium diphtheriae, C. ulcerans , and, rarely, C. pseudotuberculosis ( 1 - 3 ). (cdc.gov)
- shows high identity to proteins identified in several P. gingivalis strains [17, 19]. (erksignal.com)
- Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
- I went with the former, as did Greg, and the other Peter Assessing the Genotypic Differences between Strains of Corynebacterium pseudotuberculosis biovar equi through Comparative Genomics. (btfrocks.com)
Diphtheriae8
- Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
- The genus contains the species Corynebacterium diphtheriae and the nondiphtherial corynebacteria, collectively referred to as diphtheroids. (medscape.com)
- In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum . (medscape.com)
- For more information about C diphtheriae infections, please see Diphtheria . (medscape.com)
- C diphtheriae infection typically is characterized by a local inflammation, usually in the upper respiratory tract, associated with toxin-mediated cardiac and neural disease. (medscape.com)
- Corynebacterium diphtheriae is responsible for both endemic and epidemic diphtheria. (who.int)
- Corynebacterium diphtheriae est responsable à la fois de la diphtérie endémique et épidémique. (who.int)
- From the nasopharynx of a 5-year-old child it was excreted amicroorganism which is identical to Corynebacterium diphtheriae dose according to morphological and biochemical signs.Microorganism does not produce exotoxin. (eneutron.info)
Species7
- citation needed] It was finally renamed Corynebacterium pseudotuberculosis in 1948, to reflect that the clinical disease signs were similar to disease caused by M. tuberculosis species. (wikipedia.org)
- This bacterial species has caused occasional cases of infection in people who work closely with infected small ruminants, resulting in similar swellings of the lymph nodes in the neck and groin. (wikipedia.org)
- Interestingly, we found that HmuY is similar to proteins encoded in several different species belonging to the Bacteroidetes phylum, which consists of three classes: Bacteroidetes, Flavobacteria, and Sphingobacteria [23]. (erksignal.com)
- Central nervous system (CNS) infections comprise life-threatening clinical conditions in domestic species, and are commonly related to severe sequelae, disability, or high fatality rates. (bvsalud.org)
- A set of bacterial pathogens have been identified in central nervous infections in livestock and companion animals, although the most of descriptions are restricted to case reports and a lack of comprehensive studies involving CNS-related bacterial infections have been focused on a great number of domestic species. (bvsalud.org)
- The phages exhibited relatively wide host ranges among Yersinia pseudotuberculosis and related species. (mdpi.com)
- In general the agents implicated in etiology of respiratory syndrome include a wide spectra of viruses such as PI 3, Adeno and Reo viruses, bacterial species such as Hemophilus, Bordetella, Pasteurella, Corynebacterium, Mycoplasma and Chlamydia along with a chain of predisposing factors mainly the environmental and managemental fluctuations. (cswri.res.in)
Equi1
- Rectal palpation can reveal abdominal masses including neoplasia or abscesses due to metastatic Streptococcus equi subspecies equi or Corynebacterium pseudotuberculosis infections. (dvm360.com)
Bacteria1
- While infection can occur by the fecal-oral route, ingestion of bacteria in raw or undercooked seafood, usually oysters, is the predominant cause the acute gastroenteritis caused by V. parahaemolyticus. (datapunk.net)
Acquired immunity1
- Vaccines have also been produced to develop acquired immunity to this infection. (wikipedia.org)
Facultative1
- This bacterium is grown at 37 °C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe. (wikipedia.org)
Genus2
- citation needed] Shortly after, it was sampled from abscesses in a sheep by Hugo von Preisz [hu], and the bacterium was named the "Preisz-Nocard" bacillus until further work by German microbiologists in the mid-1900s, when it was recategorized into the Corynebacterium genus. (wikipedia.org)
- Phylogenetic analyses of the Corynebacterium genus were performed using house-keeping loci but also secreted protein loci from Cp 3/99-5. (gla.ac.uk)
Pathogenic1
- In some cases, however, it is pathogenic and causes infection, including yeast infections that are contracted by many women. (umaine.edu)
Ulcerative2
- A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
- citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
Domesticated sheep and goats1
- Infection of domesticated sheep and goats has been found across the globe. (wikipedia.org)
Sheep4
- citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)
- General Information: This disease is found in all the world's major sheep and goat production areas, causing significant economic losses worldwide, mainly due to the reduction of wool, meat and milk yields, decreased reproductive efficiencies of affected animals and condemnation of carcasses and skins in abattoirs. (up.ac.za)
- During 1985-88, in sheep and goats, 7.01% of the animals were found positive for BTV antibodies on AGPT. (cswri.res.in)
- The management system also found to affect the sero-prevalence of BTD and it was higher in migratory flocks (63.29% in sheep to 84.84% in goats) compared to stationary flocks (35.03% in sheep to 72.88% in goats). (cswri.res.in)
Corynebacterial1
- [ 5 ] Today, the more common scenario is nondiphtherial corynebacterial bacteremia associated with device infections (venous access catheters, heart valves, neurosurgical shunts, peritoneal catheters), as well as meningitis , septic arthritis , and urinary tract infections. (medscape.com)
Bacterium4
- Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
- Infection with this bacterium is often confirmed by bacterial culture of the purulent exudate. (wikipedia.org)
- C. pseudotuberculosis is a Gram-positive bacterium that can be either coccoid or filamentous rods, which can be organized into palisades. (wikipedia.org)
- Vibrio parahaemolyticus is a curved, rod-shaped, Gram-negative bacterium found in brackish saltwater, which, when ingested, causes gastrointestinal illness in humans. (datapunk.net)
20221
- Nigéria, en décembre 2022 et publie depuis lors des rapports mensuels. (who.int)
Analyses1
- Analyses of the Cp 3/99-5 genome identified several potential diagnostic candidates and seven protein targets were investigated further. (gla.ac.uk)
Genes1
- Aside from the T3SS, two genes encoding well-characterized virulence proteins are typically found on the PAI, the thermostable direct hemolysin gene (tdh) and/or the tdh-related hemolysin gene (trh). (datapunk.net)
Clinical2
- In some cases, the infection produces few obvious clinical signs in the animal, remaining unrecognized until a post-mortem examination has been carried out and, making it difficult to obtain definitive data about prevalence of the disease. (up.ac.za)
- On the basis of our mutational analysis of HmuY heme ligands [20], an initial step in Rigosertib clinical trial heme transfer could involve disruption of only one of the two axial histidine ligands, as found for Serratia marcescens hemophore HasA [22]. (erksignal.com)
Isolation1
- The first isolation of C. pseudotuberculosis came from a cow lymph node in 1888, by French bacteriologist Edmond Nocard. (wikipedia.org)
Citation needed2
- citation needed] C. pseudotuberculosis can survive in soil for up to 8 months and contaminate bedding and indoor handling facilities for several weeks. (wikipedia.org)
- citation needed] In horses, arthropod vectors are considered a significant source of infection. (wikipedia.org)
Hypothetical protein1
- HP1383 restriction modification system S subunit HP1388 hypothetical protein HP1390 hypothetical protein HP1396 hypothetical protein HP1397 hypothetical protein HP1400+ iron(III) dicitrate transport protein (fecA) HP1402 type I restriction enzyme R protein (hsdR) HP1410 hypothetical protein HP1411 hypothetical protein HP1412 hypothetical protein HP1415 tRNA delta(2)-isopentenylpyrophosphate transferase (miaA). (lbl.gov)
Organism1
- Once the diagnosis has been made, treatment of the infection can begin, but this is difficult due to the nature of the organism and the lesions it forms. (wikipedia.org)
Virulence factors1
- Analysis of the coding sequences revealed the presence of several putative virulence factors, including four sortases with multiple sortase target proteins containing LPXTG motifs. (gla.ac.uk)
Respiratory2
- CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
- Some severe complications may include respiratory failure , kidney failure , and secondary infections. (mdwiki.org)
Urinary1
- and urinary tract infections and mastitis (affecting milk production) in cattle due to infection with Corynebacterium renale , Corynebacterium cystidis , Corynebacterium pilosum , and Corynebacterium bovis . (medscape.com)
Pathogenesis1
- Prion diseases are a family of fatal transmissible neurodegenerative diseases that require the cellular prion protein for both prion agent replication and prion pathogenesis. (infectiousconferences.com)
Intestinal1
- The Bacteroidetes class consists of anaerobes which are often found in high numbers in the intestinal tracts of animals and which may infect different human tissues, including periodontal tissues (see Additional file 1). (erksignal.com)
Infectious1
- certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
Horses2
- As vector patterns change with warming temperatures, C. pseudotuberculosis in horses is re-emerging in the United States. (wikipedia.org)
- In this situation most of the horses in the herd are found to be thin, rather than a single individual. (dvm360.com)
Vaccine1
- Different immunity patterns in the 2 populations suggested that the low immunity among children caused by low vaccination coverage increased transmission, resulting in symptomatic infections at school-going age, when vaccine-induced immunity waned most. (cdc.gov)
Resistance1
- Specifically, C. pseudotuberculosis is intrinsically resistant to streptomycin, with varying resistance to penicillin and neomycin depending on the strain. (wikipedia.org)
Attempts1
- Attempts were made to express these candidates as recombinant proteins, however, only two recombinants were successfully expressed and purified, Cp3995_0570 and CP40. (gla.ac.uk)
Disease3
- Wound infections also occur, but are less common than seafood-borne disease. (datapunk.net)
- The disease mechanism of V. parahaemolyticus infections has not been fully elucidated. (datapunk.net)
- Clinically, HGA is essentially indistinguishable from human monocytic ehrlichiosis , the infection caused by Ehrlichia chaffeensis , and other tick-borne illnesses such as Lyme disease may be suspected. (mdwiki.org)
Distinct1
- Each PAI variant contains a genetically-distinct Type III Secretion System (T3SS), which is capable of injecting virulence proteins into host cells to disrupt host cell functions or cause cell death by apoptosis. (datapunk.net)
Secondary1
- Quite often the cause of secondary immunodeficiency is an infection involvement, when the causative agents propagate directly in the cells of immune system and destroy it. (eneutron.info)
Isolates2
Addition1
- In addition, in this report we examined the participation of HmuY protein in biofilm formation. (erksignal.com)
Ulcers1
- Skincare with 2 hourly turns to prevent decubitus ulcers, intermittent catheterisation to prevent overdistension of bladder and infection. (abcmedicalnotes.com)
Study1
- however Therefore the aim of this study was to analyze the surface exposure and expression of HmuY protein in P. gingivalis. (erksignal.com)
Group1
- Based on this reclassification, for example, Corynebacterium haemolyticum became Arcanobacterium haemolyticum and the JK group became Corynebacterium jeikeium . (medscape.com)
Host1
- Bacterial exported proteins represent key components of the host-pathogen interplay. (biomedcentral.com)