• gene
  • p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence. (uniprot.org)
  • The α-neuraminidase protein is coded for by the NEU1 gene and is, a glycohydrolitic enzyme that is active in the lysosome. (up.edu)
  • Alternatively, the missense mutation identified in the GLB1 gene may alter the ß-galactosidase protein sufficiently that it impairs the overall structure of the LMC resulting in the secondary deficiency of α-neuraminidase. (up.edu)
  • data
  • Accumulating data from other disease models also suggest that inhibition of axonal transport leads to neurodegeneration ( Chevalier-Larsen and Holzbaur, 2006 ), presumably through inhibition of neurotrophic signaling. (jneurosci.org)
  • source
  • p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)
  • mouse
  • Transport defects have also been observed in more rapidly progressive neurodegeneration, such as that observed in the SOD1 G93A transgenic mouse model for familial amyotrophic lateral sclerosis (ALS). (jneurosci.org)
  • cell
  • COPE Full-Length MS Protein Standard (NP_009194), Labeled with [U- 13C6, 15NL-Arginine and [U- 13C6, 15NL-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. (creative-proteomics.com)
  • YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta. (ox.ac.uk)