• determined by X-ray crystallogr
  • Using the Snob program for information-theoretic Minimum Message Length (MML) intrinsic classification, we are able to take the protein dihedral angles as determined by X-ray crystallography, and cluster sets of dihedral angles into groups. (psu.edu)
  • Abstract
  • Abstract Tricodon regions on messenger RNAs corresponding to a set of proteins from Escherichia coli were scrutinized for their translation speed. (bio.net)
  • spectra
  • Since proteins consist of chiral amino acids, they are CD active and exhibit distinct CD spectra that are sensitive to the protein's secondary structure. (olisweb.com)
  • This spectra can provide a qualitative snapshot of the protein structure or the secondary structure composition of a protein can be estimated from the far UV CD spectrum using a number of algorithms, several of which are made available in Olis GlobalWorks software. (olisweb.com)
  • Our results provide a foundation for the development of spectroscopic markers based on the recently proposed Protein Charge Transfer Spectra (ProCharTS) which are relevant for the study of DNA-binding or intrinsically disordered proteins that are rich in charged amino acids. (rsc.org)
  • circular dichroism
  • A powerful tool used to monitor secondary structure is circular dichroism (CD), which is the differential absorbance of left and right circularly polarized light. (olisweb.com)
  • The protein secondary structure and pigments' microenvironment in photosystem 1 (PS1) complexes were studied in the temperature range of 25-80 °C using Fourier transform infrared (FT-IR) and circular dichroism (CD) spectroscopy, respectively. (springer.com)
  • computational
  • Rosetta development began in the laboratory of Dr. Baker as a structure prediction tool but since then has been adapted to solve common computational macromolecular problems. (wikipedia.org)
  • In 2010, he again became a finalist and went on to receive the Pioneer Award for his Computational Analysis of Novel Drug Opportunities (CANDO) drug discovery platform to screen every known drug against every known target structure in a shotgun manner to discover new repurposeable therapeutics, particularly for underserved diseases. (wikipedia.org)
  • motif
  • We found out that the motif of secondary structure "beta strand-major binder-random coil" is overrepresented around all the three major Mn 2+ binders. (hindawi.com)
  • On the other hand, the percentage of Mn 2+ sites with at least one amino acid in the "beta strand-major binder-random coil" motif of secondary structure (77.88%) does not depend on genomic GC-content. (hindawi.com)
  • Bayesian
  • Previous work by Hunter and States had applied a similar Bayesian classification method, AutoClass, to protein data with site position represented by 3 Cartesian co-ordinates for each of the α-Carbon, β-Carbon and Nitrogen, totalling 9 co-ordinates. (psu.edu)
  • side chains
  • Indeed, denatured (unfolded) proteins have rather similar characteristics, a kind of homogeneolLs "averapL:" of their r,mdomly dangling side chains. (coursehero.com)
  • fold
  • Detailed consideration of the dynamic behavior or proteins and how they fold to their native structllfcs is deferred until Chapter 9. (coursehero.com)
  • transitions
  • The absorption of light by proteins can induce charge transfer (CT) transitions in the UV-visible range of the electromagnetic spectrum. (rsc.org)
  • Near-infrared CD is used to investigate geometric and electronic structure by probing metal d→d transitions. (wikipedia.org)