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Pituitary GlandPituitary Gland, AnteriorPituitary NeoplasmsPituitary DiseasesPituitary HormonesPituitary Gland, PosteriorProlactinPituitary Hormones, AnteriorPituitary Gland, IntermediateSalivary GlandsPituitary ApoplexyHypopituitarismAdenomaGrowth HormoneAdrenocorticotropic HormoneMammary Glands, AnimalLuteinizing HormoneGonadotropins, PituitaryExocrine GlandsSubmandibular GlandGonadotropin-Releasing HormoneProlactinomaHypophysectomyPituitary Function TestsPro-OpiomelanocortinFollicle Stimulating HormoneAdrenal GlandsSella TurcicaSomatotrophsPituitary Adenylate Cyclase-Activating PolypeptideParotid GlandHypothalamusThyrotropin-Releasing HormoneLactotrophsGonadotrophsReceptors, LHRHThyrotropinACTH-Secreting Pituitary AdenomaAdenoma, ChromophobeFollicle Stimulating Hormone, beta SubunitSweat GlandsDwarfism, PituitaryPituitary ACTH Hypersecretionbeta-LipotropinGrowth Hormone-Releasing HormoneHypothalamo-Hypophyseal SystemSebaceous GlandsPituitary Hormone-Releasing HormonesTranscription Factor Pit-1Sublingual GlandRNA, MessengerEndorphinsRadioimmunoassayBromocriptineLuteinizing Hormone, beta SubunitThyrotropin, beta SubunitHarderian GlandGrowth Hormone-Secreting Pituitary AdenomaSphenoid SinusGlycoprotein Hormones, alpha SubunitCastrationHuman Growth HormoneReceptors, Pituitary Hormone-Regulating HormoneSheepEstradiolbeta-EndorphinImmunohistochemistryHyperprolactinemiaMelanocyte-Stimulating HormonesCentral Nervous System CystsCorticotrophsSalivary Gland NeoplasmsRats, Inbred StrainsOvariectomyEmpty Sella SyndromeDiabetes InsipidusMedian EminenceCorticotropin-Releasing HormoneDiencephalonGonadotropinsHydrocortisoneReceptors, Pituitary HormoneAdenoma, BasophilMelanotrophsOrgan SizeDiabetes Insipidus, NeurogenicSphenoid BoneCushing SyndromeReceptors, Pituitary Adenylate Cyclase-Activating PolypeptideEndocrine GlandsPituitary-Adrenal SystemMagnetic Resonance ImagingLactationPregnancyTestosteroneParathyroid GlandsSalivary Gland DiseasesNeuropeptidesPituitary IrradiationMolecular Sequence Data
HormoneHormonesTumorHypothalamusAdenomaPosterior pituiProlactinOvariesTumorsReceptorsStimulatesHypothalamic-pituitarySynthesized and secretedAdrenal glandPolypeptideAmino acidMetabolismGrowthTissuesSecretesMutationsSomatotropicPeptideEndocrinologyCellsOlfactoryACTHTissueImmunohistochemistryLiverBindsSitu hybridizationMalignantMembraneThyroid glandReproductiveGonadotropesEstrogenPeptidesEstradiolReceptorFunctionCytoplasmicBound
Hormone70
Hormones11
Tumor6
  • In both sexes, the presence of a pituitary tumor may cause visual-field defects or headache. (medscape.com)
  • The clinical features of pituitary adenoma vary depending on the location and size of the tumor and its secretory capability. (medscape.com)
  • C3414 Thyroid Tumor C90259 Pediatric Terminology A C3879 Thyroid Gland Medullary Carcinoma Medullary Thyroid Carcinoma C Cell Carcinoma A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. (nih.gov)
  • C3268 Nervous System Neoplasm C90259 Pediatric Terminology A C3502 Thyroid Gland Follicular Adenoma Thyroid Adenoma A benign, encapsulated tumor, arising from the follicular cells of the thyroid gland. (nih.gov)
  • C3250 Acute Myeloid Leukemia with Maturation C90259 Pediatric Terminology A C3878 Thyroid Gland Undifferentiated (Anaplastic) Carcinoma Anaplastic Thyroid Carcinoma Undifferentiated Thyroid Tumor A primary carcinoma of the thyroid gland composed of undifferentiated cells. (nih.gov)
  • C3414 Thyroid Tumor C90259 Pediatric Terminology A C3342 Prolactin-Producing Pituitary Gland Adenoma Prolactinoma An adenoma of the anterior lobe of the pituitary gland that produces prolactin. (nih.gov)
Hypothalamus7
Adenoma5
  • For pituitary adenoma imaging, CT and MRI have largely replaced plain radiography because conventional radiography is poor for delineating soft tissues. (medscape.com)
  • Sanmillan et al retrospectively analyzed 294 surgically treated pituitary adenoma (148 by microsurgical transsphenoidal approach and 146 by endoscopic endonasal approach). (medscape.com)
  • They found that pituitary adenoma volume and cavernous sinus invasion (graded with the Knosp scale), when used in combination, could predict the complexity of the surgery and the difficulty of achieving gross total resection. (medscape.com)
  • C3329 Pituitary Gland Adenoma C90259 Pediatric Terminology A C5448 Malignant Childhood Central Nervous System Neoplasm Malignant Childhood Central Nervous System Neoplasm Malignant neoplasms which occur in the brain, spinal cord, or meninges of children. (nih.gov)
  • C5132 Childhood Central Nervous System Neoplasm C90259 Pediatric Terminology A C7462 ACTH-Producing Pituitary Gland Adenoma ACTH-Producing Pituitary Adenoma An adenoma of the pituitary gland that produces corticotropin. (nih.gov)
Posterior pitui2
Prolactin3
Ovaries1
Tumors8
  • These lactotroph adenomas are called prolactinomas and account for approximately 40% of all pituitary tumors. (medscape.com)
  • General indications for pituitary surgery include patient drug intolerance, tumors resistant to medical therapy, patients who have persistent visual-field defects in spite of medical treatment, and patients with large cystic or hemorrhagic tumors. (medscape.com)
  • In general, pituitary lesions can be subdivided into nonsecretory and secretory tumors of the pituitary gland, other intrasellar tumors, and parasellar tumors. (medscape.com)
  • The last group occurs in the vicinity of the sellar turcica and can mimic the pituitary tumors in terms of the symptoms they cause. (medscape.com)
  • Nonsecretory pituitary tumors are called null-cell tumors. (medscape.com)
  • Small null-cell tumors measuring a few millimeters are common and found in up to 25% of autopsied pituitary glands. (medscape.com)
  • As pituitary tumors grow, destruction of normal pituitary tissue results in various hormonal deficiencies. (medscape.com)
  • The optic chiasm is directly above the pituitary gland, and upward growth of pituitary tumors frequently causes progressive visual loss. (medscape.com)
Receptors5
  • These properties of the toxin follow from the fact that it structurally resembles activated G protein receptors when placed in a phospholipid environment. (wikipedia.org)
  • The membrane receptors activate the creation of mRNA and can change protein expression: basically, they can change gene expression. (trincoll.edu)
  • It does this by binding with receptors on these two glands, which notifies them to stop producing CRH and ACTH. (trincoll.edu)
  • Over 20 GnRHs have been identified in vertebrates and protochoordates and shown to bind cognate G-protein couple receptors (GnRHR). (ualg.pt)
  • This is the first report showing five GnRH receptors in a vertebrate species and the gene expression patterns support the concept that GnRH and GnRHRs play highly diverse functional roles in the regulation of cellular functions, besides the "classical" role of pituitary function regulation. (ualg.pt)
Stimulates3
  • Estrogen stimulates the proliferation of pituitary lactotroph cells, resulting in an increased quantity of these cells in premenopausal women, especially during pregnancy. (medscape.com)
  • In adults, GH stimulates protein synthesis in muscle and the release of fatty acids from adipose tissue (anabolic effects). (medlineplus.gov)
  • The major role of HGH is to stimulate the liver to secrete Insulin-like Growth Factor-I (IGF-I). IGF-I stimulates production of cartilage cells, resulting in bone growth and also plays a key role in muscle protein synthesis and organ growth. (steroidpowdercanada.com)
Hypothalamic-pituitary3
  • [ 2 ] However, hyperprolactinemia can also be from a pharmacologic cause or some other pathologic problem of the hypothalamic-pituitary dopaminergic pathways. (medscape.com)
  • The pituitary gland is the master gland of the body because it controls most of the body's endocrine functions by means of the hypothalamic-pituitary axis (see the images below). (medscape.com)
  • Follicular release occurs around 14 days prior to menstruation in a cyclic pattern if the hypothalamic-pituitary-ovarian axis function is well regulated. (nih.gov)
Synthesized and secreted1
Adrenal gland1
  • Measurements of DHEAS provides information about the adrenal gland function and can help with the diagnosis of congenital adrenal hyperplasia and polycystic ovary syndrome. (cdc.gov)
Polypeptide2
  • Released from the somatotroph cells within the lateral wings of the brain's anterior pituitary gland, GH, a protein-based, 191-amino acid polypeptide, controls many bodily processes - from fat loss to bone growth to muscle building. (allmaxnutrition.com)
  • ‍ amino acid polypeptide secreted by the anterior pituitary gland. (khanacademy.org)
Amino acid3
  • Length' refers to the number of amino acid residues in the protein of interest. (khanacademy.org)
  • 1. The proteins encoded by these genes are classified as alpha or beta forms on the basis of the predicted amino acid sequences and have homologs in man. (everypatent.com)
  • It works as an energy resource and also as a protein building amino acid. (musclemaniaclub.com.my)
Metabolism4
  • The pituitary gland helps control growth as well as blood pressure, energy management, all functions of the sex organs, thyroid glands and metabolism, temperature regulation and pain relief. (proteopedia.org)
  • They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system. (lookformedical.com)
  • Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. (lookformedical.com)
  • hGH affects protein, fat, carbohydrate and mineral metabolism. (steroidpowdercanada.com)
Growth8
  • Here, we report the investigation of transforming growth factor beta-receptor 3 like (TGFBR3L), an uncharacterised pituitary specific membrane protein, in non-neoplastic anterior pituitary gland and pituitary neuroendocrine tumours. (nih.gov)
  • Once we have begun to stimulate muscle growth through hypertrophy-focused training, protein-centric eating and optimal rest and recovery we still must fully translate these positive actions into concrete muscle-building gains. (allmaxnutrition.com)
  • Hgh, produced by the pituitary gland, spurs growth in children and adolescents. (ancienttoadcounseling.com)
  • The excessive levels of somatomedin C, however, promote protein synthesis and growth in a variety of tissues such as the bone cartilage, soft tissues, especially in the head and neck region. (petmd.com)
  • HGH enhances tissue growth by stimulating protein formation. (grizzlyroids.shop)
  • GH causes genes in the nucleus of its target cells to increase production of proteins that are necessary for cell growth. (thehealthboard.com)
  • HGH enhances tissue growth by stimulating protein formation, anabolics com scam. (table-tennis-player.club)
  • At a young age, it is produced by the pituitary gland in a considerable amount to provide the body with adequate growth in order to form a fully healthy shape of the limbs, lay a functional reproductive system, and achieve standard height. (hghinformations.com)
Tissues3
  • TGFBR3L showed membranous immunolabeling and was found to be gonadotroph cell lineage-specific, verified by co-expression with SF1 and FSH/LH staining in both tumour and non-neoplastic anterior pituitary tissues. (nih.gov)
  • Peptides are a tiny protein, or you can say the short-chain of proteins including less than 50 amino acids and plays a crucial role in structure DNA, tissues, genes, and hormonal agents. (highgrade-labs.com)
  • Totally 6076 proteins in NFPA tissues were identified, and 3598 DEGs between NFPA and control tissues were identified from GEO database. (frontiersin.org)
Secretes1
Mutations1
  • One of the key differences about the other isoforms is that since they are lacking certain sections of amino acids, then the single point mutations that naturally occur in those regions will not affect the function or activity of the isoform proteins. (proteopedia.org)
Somatotropic2
Peptide4
  • The pre-protein contains a 26 residue-long signal peptide located on the N-terminus of the protein, which is cleaved off to create the mature protein. (proteopedia.org)
  • The signal peptide acts as an anchor to keep the pre-protein bound to the membrane of the endoplasmic reticulum (ER). (proteopedia.org)
  • When these peptide chains linked together, they produce proteins. (highgrade-labs.com)
  • Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase. (wikidata.org)
Endocrinology1
  • This paper reviews the main landmarks in the history of thyroid disease, supplemented by a brief discussion of the historically relevant scientific aspects of the thyroid gland, and the evolution of endocrinology as a formal discipline. (who.int)
Cells12
  • Objective: We hypothesized that long-term exposure to low concentrations of B[ a ]P might disrupt testosterone production in Leydig cells via an alteration of steroidogenic proteins. (nih.gov)
  • The GH1 is expressed mainly in somatotrope cells of the pituitary gland. (proteopedia.org)
  • Chicken FSHβ mRNA-expressing (-ex) and -immunopositive (-ip) cells started to appear in the ventral part of the caudal lobe in the anterior pituitary gland at E8. (bioone.org)
  • In conclusion, TGFBR3L is a novel pituitary gland specific protein, located in the membrane of gonadotroph cells in non-neoplastic anterior pituitary gland and in a subset of gonadotroph pituitary tumours. (nih.gov)
  • In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testes and is critical for spermatogenesis. (loinc.org)
  • A C8054 Thyroid Gland Follicular Carcinoma Follicular Thyroid Carcinoma A differentiated adenocarcinoma arising from the follicular cells of the thyroid gland. (nih.gov)
  • Carcinoma arising from the C-cells of the thyroid gland. (nih.gov)
  • A non-malignant neoplasm of the thyroid gland arising from epithelial cells. (nih.gov)
  • An aggressive carcinoma of the thyroid gland composed of undifferentiated cells. (nih.gov)
  • In the SASP of cells that became senescent following several in vitro chemical and physical stress, we identified the IGFBP-4 protein that can be considered a general stress mediator. (elifesciences.org)
  • Somatotropin is secreted by the anterior pituitary gland, where it is made by the cells called somatotrophs. (thehealthboard.com)
  • Estrogens diffuse into their target cells and interact with a protein receptor. (demegaformulations.info)
Olfactory2
  • The CLP phenotype was accompanied by olfactory bulb hypoplasia and anterior pituitary aplasia, but otherwise grossly normal brain morphology. (nih.gov)
  • Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. (nih.gov)
ACTH1
  • Cortex receives ACTH from the pituitary, it starts producing cortisol. (trincoll.edu)
Tissue2
  • Western blot analysis of a protease-resistant form (PrPres) of a normal cellular prion protein in nerve tissue samples obtained from cattle 10 (A) and 16 (B) months postinoculation (cattle identification codes 8515 and 1061, respectively). (cdc.gov)
  • This study established the large-scale quantitative protein profiling of NFPA tissue proteome. (frontiersin.org)
Immunohistochemistry1
Liver1
Binds1
  • In humans, NKG2D binds to a family of eight proteins known as NKG2D ligands. (mdpi.com)
Situ hybridization1
Malignant1
  • Pituitary adenomas are almost always benign with no malignant potential. (medscape.com)
Membrane1
  • The now active protein releases from the membrane into the ER lumen and is exported out of the cell. (proteopedia.org)
Thyroid gland3
Reproductive1
  • It is performed when certain reproductive or pituitary disorders are suspected. (myshopify.com)
Gonadotropes1
  • To the best of our knowledge, this is the first report focusing on the differentiation of chicken gonadotropes by assessment of both protein and mRNA of chicken gonadotropin. (bioone.org)
Estrogen1
Peptides1
  • Generally, companies break down proteins into peptides to make them much easier to absorb. (highgrade-labs.com)
Estradiol1
  • About 98% of estradiol is bound to transport proteins (SHBG and albumin). (cdc.gov)
Receptor2
  • GnRHR is a G protein-coupled receptor (GPCR) coupled to Gαq/11 protein and, to a lesser extent, to Gαi/Gαs proteins, simultaneously activating Ca2+, β-cate. (endocrine-abstracts.org)
  • All European sea bass receptor mRNAs are expressed in the anterior and mid brain, and all but one are expressed in the pituitary gland. (ualg.pt)
Function2
Cytoplasmic1
Bound1
  • At the same time, it promotes dissociation of any bound GDP from the protein, enhancing GTP binding. (wikipedia.org)