Von Hippel-Lindau Tumor Suppressor Proteinvon Hippel-Lindau DiseasePancreatic CystHypoxia-Inducible Factor 1, alpha SubunitKidney NeoplasmsCarcinoma, Renal CellProcollagen-Proline DioxygenaseTumor Suppressor Protein p53Ubiquitin-Protein LigasesNobel PrizeTumor Suppressor ProteinsGenes, Tumor SuppressorProteasome Endopeptidase ComplexHemangioblastomaProteasome InhibitorsRho FactorTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2von Willebrand FactorMolecular Sequence DataMutationApoptosisProtein BindingNuclear ProteinsGenes, p53Cysteine EndopeptidasesCell LineGene Expression Regulation, NeoplasticMultienzyme ComplexesDNA-Binding ProteinsNeurofibromin 2TransfectionTranscription FactorsAdenomatous Polyposis Coli ProteinCell CycleTumor Cells, CulturedLeupeptinsAmino Acid SequenceCyclin-Dependent Kinase Inhibitor p16Cell Cycle ProteinsSignal TransductionProto-Oncogene ProteinsGenes, SuppressorCyclin-Dependent Kinase Inhibitor p21Base SequencePTEN PhosphohydrolasePromoter Regions, GeneticCell ProliferationLigasesCell Transformation, NeoplasticPhosphorylationProteinsDNA DamageBlotting, WesternTranscription, GeneticNeoplasmsNeoplasm ProteinsDown-RegulationCell DivisionProtein Structure, TertiaryCyclinsRNA, MessengerUbiquitinsRepressor ProteinsE2F Transcription FactorsTranscriptional Activationvon Willebrand DiseasesTumor Markers, BiologicalHeLa CellsBinding SitesCarrier ProteinsCysteine Proteinase InhibitorsGene SilencingCells, CulturedRNA InterferenceCell HypoxiaUbiquitinationProtein-Serine-Threonine KinasesRecombinant Fusion ProteinsRNA, Small InterferingE2F1 Transcription FactorGene Expression RegulationFibroblastsReverse Transcriptase Polymerase Chain ReactionSuppressor of Cytokine Signaling ProteinsBoronic AcidsCell NucleusSuppression, GeneticDNA MethylationGene DeletionOncogene Proteins, ViralLoss of HeterozygosityTranscription Factor DP1PyrazinesPapillomavirus E7 ProteinsTrans-ActivatorsWT1 ProteinsTumor Burden