• infusion
  • Secondary hypothesis: The use of a Precedex infusion, in addition to propofol during surgery will provide improved hemodynamic stability. (clinicaltrials.gov)
  • Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder. (pubtransformer.com)
  • The objective of this report of a fatal propofol-related infusion syndrome in a young adult was to present-to our knowledge for the first time-direct ultrastructural evidence for the central role of mitochondrial damage in the pathogenesis of this syndrome. (pubtransformer.com)
  • PMID- 29252954 OWN - NLM STAT- In-Process LR - 20171218 IS - 1530-0293 (Electronic) IS - 0090-3493 (Linking) VI - 46 IP - 1 DP - 2018 Jan TI - Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder. (pubtransformer.com)
  • PG - e91-e94 LID - 10.1097/CCM.0000000000002802 [doi] AB - OBJECTIVE: The objective of this report of a fatal propofol-related infusion syndrome in a young adult was to present-to our knowledge for the first time-direct ultrastructural evidence for the central role of mitochondrial damage in the pathogenesis of this syndrome. (pubtransformer.com)
  • The patient was intubated, then propofol infusion started, and a craniotomy was performed to remove an intracerebral hematoma. (pubtransformer.com)
  • Peripheral blood analysis revealed increased levels of acetyl-, propionyl-, butyryl-, malonyl-, and valeryl-carnitine as an indicator for propofol-related infusion syndrome, as well as for propofol-mediated inhibition of free fatty acid uptake into mitochondria, affecting beta-oxidation. (pubtransformer.com)
  • CONCLUSIONS: Electron dense bodies found in association with mitochondria in muscle and liver cells probably correspond to accumulation of free fatty acid provide direct morphological evidence for the mitochondrial damage in propofol-related infusion syndrome. (pubtransformer.com)
  • Sixty-6 ASA physical status I and II patients were given either dexmedetomidine (1 μg/kg over 10 minutes followed by a continuous infusion of 0.5 μg/kg/h throughout surgery) or comparable volumes of saline as a placebo. (lww.com)
  • The clinically useful infusion rates are 0.025-0.1 (µg/kg)/min for sedation (rates adjusted to age of patient, severity of their illness and invasiveness of surgical procedure). (wikipedia.org)
  • A target plasma concentration is entered as ng/ml into the pump, which calculates its infusion rate according to patient factors like age and weight. (wikipedia.org)
  • sedatives
  • These side effects are often controlled by either altering the administered dose (decreasing or in some cases, increasing the dose) or by administering other sedatives that allow the patient to tolerate or lose awareness of the side effect. (wikipedia.org)
  • acute
  • In some patients, blood flow remains depressed throughout the acute postinjury period, with marked blunting of the second phase, whereas in others a rise in CBF to nearly normal levels occurs early after injury and may remain elevated during both the second and third phases. (c3.hu)
  • respiratory
  • patients with severe cardiovascular or respiratory diseases (ASA IV or higher). (clinicaltrials.gov)
  • After the ABC (airway, breathing, circulation) is evaluated and normalised, a primary survey of the patient is performed to evaluate the four priority patient systems (respiratory, cardiovascular, neurological and urinary). (vin.com)
  • In non-ventilated patients, respiratory depression is common and chest wall rigidity may occur at doses larger than 4ug/kg9. (bioportfolio.com)
  • pulmonary
  • patients at risk for pulmonary aspiration eg patients with history of GERD, gastroparesis (eg diabetic) and obesity. (clinicaltrials.gov)
  • The aim of the study was to evaluate effectiveness of addition of dexmedetomidine to paravertebral block with bupivacaine in improving the postoperative pain relief and pulmonary functions in patients undergoing thoracic surgeries. (readbyqxmd.com)
  • brain
  • Awake craniotomy for removal of brain tumour is performed because the tumour may be located close to areas of the brain that control specific functions such as movement or speech. (clinicaltrials.gov)
  • Successful management requires an understanding of brain injury, patient stabilisation and flat-bone fracture repair. (vin.com)
  • Their incidence increases with age, and approximately one-sixth of patients with cancer develop a brain metastasis which is symptomatic in most cases and often the controlling variable for survival. (neuroanesthesia.info)
  • In the human brain, a type of reduced activity called burst suppression occurs at a mean temperature of 24°C, and electrocerebral silence occurs at a mean temperature of 18°C. The achievement of measured electrocerebral silence has been called "a safe and reliable guide" for determining cooling required for individual patients, and verification of electrocerebral silence is required prior to stopping blood circulation to begin a DHCA procedure. (wikipedia.org)
  • systemic
  • Therefore, the priority in emergency management of trauma patients is correction of systemic physiological abnormalities. (vin.com)
  • Time
  • Despite city recurrence being approximately half of that reported in one-time adjuvant trials, distant disease apostasy quiet occurred in more than 70 % of patients. (tas.com)
  • fentanyl
  • The most common side effects reported by patients receiving this medication are a sense of extreme "dizziness" (often short lived, a common side effect of other fast-acting synthetic phenylpiperidine narcotics such as fentanyl and alfentanil) and intense itching (pruritus), often around the face. (wikipedia.org)
  • dose
  • Barbiturates and propofol are associated with a dose-dependent taper off in CMAP amplitude and need as a service to more forward stimulation patterns to produce almost identical CMAP waveforms cheap 25 mg lamotrigine with mastercard treatment junctional rhythm. (tas.com)
  • feasibility
  • Objective:To report the feasibility of craniectomy with duraplasty in four patients with life-threatening encephalitis and, in particular, their long-term outcome. (ebscohost.com)
  • Drug
  • Many anesthesiologists simply use boluses of propofol - a reliable way of accomplishing this effect with a familiar drug. (bioportfolio.com)
  • blood
  • The usual way to give these medications is by the anesthesiologist assessing pain level, watching the patient and monitoring blood pressure and heart rate. (clinicaltrials.gov)
  • DATA SOURCES: Histological and electron microscopical analysis of liver, skeletal, and heart muscle obtained by autopsy and blood obtained from patient. (pubtransformer.com)
  • It is postulated that for the majority of patients, this rise in blood flow results from an increase in metabolic demands in the setting of intact vasoreactivity. (c3.hu)
  • group
  • and Group 3 (34 patients), CBF greater than or equal to 33 ml/100 g/minute on all measurements. (c3.hu)
  • survival
  • 2009) reported on a retrospective anal- ysis of prognostic factors for survival among patients treated with curatively intended salvage re-irradiation towards principal and neck cancer. (tas.com)