• The new barbiturate was synthesized by the German chemist Emil Fischer in 1904, 2 years after the first barbiturate, barbiturate, was synthesized. (chemsline.com)
  • Josef von Mering helped to discover barbiturates, a class of sedative drugs used for insomnia, epilepsy, anxiety, and anesthesia. (wikipedia.org)
  • In small doses phenobarbital has a sedative effect and in combination with other drugs (antispasmodics, vasodilators) it is used in neurovegetative disorders. (chemsline.com)
  • One of the properties of phenobarbital is its ability to cause "induction" of enzymes and increase the activity of monooxygenase enzyme system of the liver, which should be considered when using it simultaneously with other drugs, the effect of which may be weakened (see Benzonal). (chemsline.com)