• Phenotype
  • The gene then needs to be mapped by comparing the inheritance of the phenotype with other known genetic markers. (wikipedia.org)
  • Unlike traditionally animal and plant breeding, which involves doing multiple crosses and then selecting for the organism with the desired phenotype, genetic engineering takes the gene directly from one organism and inserts it in the other. (wikipedia.org)
  • Nucleic Acid
  • This relies on recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro-injection, macro-injection or micro-encapsulation. (wikipedia.org)
  • Variation
  • No such association was found between mir-433 variation and Parkinson's disease despite the fact that variation in the region of the FGF20 gene which binds to mir-433, is associated with Parkinson's disease. (wikipedia.org)
  • genetically
  • Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to estrogen-induced phenotypic sex conversion. (biomedsearch.com)
  • An organism that is generated through genetic engineering is considered to be genetically modified (GM) and the resulting entity is a genetically modified organism (GMO). (wikipedia.org)
  • Genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. (wikipedia.org)
  • variants
  • Identified for the first time in the country and described the genetic, the biochemical and the clinical features of several structural defects of hemoglobins and thalassemia variants, including a point mutation in the promoter region of the gamma globin gene responsible for the Brazilian form of HbF persistence. (wikipedia.org)
  • molecular
  • Using genetic and molecular analyses we have identified WUSCHEL (WUS) as a biologically important target of the SNF2-class ATPase SPLAYED (SYD) in the shoot apical meristem of Arabidopsis. (mendeley.com)
  • A decade later molecular genetic tools have improved methods for protein identification. (wikipedia.org)
  • Molecular drive is a term coined by Gabriel Dover in 1982 to describe evolutionary processes that change the genetic composition of a population through DNA turnover mechanisms. (wikipedia.org)
  • Molecular drive operates independently of natural selection and genetic drift. (wikipedia.org)
  • After his post-doctoral training at the Oxford University, in the laboratories of Professor Sir David J. Wetherall, whose group was at the time establishing the molecular bases of the thalassemias, he returned to Brazil and started a research group with a major scientific interest in the genetic bases of hematological diseases. (wikipedia.org)
  • organism
  • Genetic engineers must first choose what gene they wish to insert into the organism. (wikipedia.org)
  • Genetic engineering is a process that alters the genetic make-up of an organism by either removing or introducing DNA. (wikipedia.org)
  • The sexual organism could henceforth pass on some of its genetic material to produce new individuals and could itself become disposable with respect to the survival of its species. (wikipedia.org)
  • estrogen
  • In this study, we show that a 170-nt region in the promoter of CYP19A1/aromatase, a key gene required for ovarian estrogen biosynthesis and feminization of chicken embryonic gonads, contains highly quantitative, nucleotide base-level epigenetic marks that reflect phenotypic gonadal sex differentiation. (biomedsearch.com)
  • regulation
  • DNA TATA box Pribnow box SOS box CAAT box CCAAT box Operator (biology) Upstream activation sequence RNA List of cis-regulatory RNA elements Polyadenylation signals, mRNA AU-rich element, mRNA Other Regulation of gene expression cis-regulatory module Gene regulatory network Operon Promoter Trans-acting factor Rfam Transterm Butler JE, Kadonaga JT (October 2002). (wikipedia.org)
  • Disorders
  • Chromatin remodeling in rodent offspring and altered gene expression within the limbic brain regions that may contribute to depression, stress, and anxiety-related disorders in future generations. (wikipedia.org)
  • Advances in genetic testing, such as exome sequencing and specific gene panels, can provide greater access to diagnoses for muscle β-enolase deficiency and other rare disorders. (wikipedia.org)
  • exon
  • The ENO3 gene spans 6 kb and contains 12 exons, though the first exon is an untranslated region and, thus, non-coding. (wikipedia.org)
  • vivo
  • Using this site-specific ChIP, we were able to confirm four previously described Sp1 binding sites within egfr promoter region to be occupied by Sp1 in vivo. (biomedsearch.com)
  • Differences
  • These results indicate the impact of this OXTR genetic variant on individual differences in social affective neural processing. (scirp.org)
  • Proteins
  • The first company to focus on genetic engineering, Genentech, was founded in 1976 and started the production of human proteins. (wikipedia.org)
  • functional
  • According to Dover, TRAM is a genetic system that has features of Non-mendelian inheritance Turnover, copy number and functional Redundancy And Modulatory. (wikipedia.org)
  • diseases
  • As well as producing hormones, vaccines and other drugs genetic engineering has the potential to cure genetic diseases through gene therapy. (wikipedia.org)
  • These data demonstrated that this Black population is significantly different from its U.S. or Caribbean counterparts, with implications for the medical genetic studies that compare these populations and for the understanding of the hereditary diseases. (wikipedia.org)
  • evolutionary
  • Only the dog contains what is considered as an Evolutionary Conserved Region (ECR). (wikipedia.org)
  • CREs are vital components of genetic regulatory networks, which in turn control morphogenesis, the development of anatomy, and other aspects of embryonic development, studied in evolutionary developmental biology. (wikipedia.org)
  • Male
  • Although the mechanisms of avian sex determination remains unknown, the genetic sex is experimentally reversible by in ovo exposure to exogenous estrogens (ZZ-male feminization) or aromatase inhibitors (ZW-female masculinization). (biomedsearch.com)
  • Risk
  • The -1185 A/G and -1051 G/A dimorphisms in the von Willebrand factor gene promoter and risk of myocardial infarction. (biomedsearch.com)
  • specific
  • This first intron, along with the 5'-flanking region, contains a consensus sequence for muscle-specific regulatory factors that includes a CC(A + T-rich)6GG box, a M-CAT-box CAATCCT, and two myocyte-specific enhancer-binding factor 1 boxes. (wikipedia.org)
  • material
  • Polymerase chain reaction (PCR), developed by Kary Mullis in 1983, allowed small sections of DNA to be amplified and aided identification and isolation of genetic material. (wikipedia.org)
  • New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by artificially synthesising the DNA. (wikipedia.org)
  • study
  • STUDY DESIGN: Variations in the exons and promoter of the NHE3 gene were analyzed with direct sequencing analysis and mini sequencing (SNaPshot analysis) in 251 cases of SIDS, plus 50 infant control subjects who had died of other causes, and 170 healthy adults. (biomedsearch.com)