Recombinant Fusion ProteinsGenes, ablFusion Proteins, bcr-ablCell ProliferationMembrane FusionViral Fusion ProteinsCell FusionLeukemia, Myelogenous, Chronic, BCR-ABL PositiveProto-Oncogene Proteins c-bcrMolecular Sequence DataProto-Oncogene Proteins c-ablBenzamidesOncogene Proteins, FusionAmino Acid SequencePyrimidinesPiperazinesSignal TransductionCell LineCells, CulturedBase SequenceK562 CellsGene FusionApoptosisSpinal FusionCell DivisionCell Line, TumorProtein-Tyrosine KinasesTransfectionPhosphorylationPhiladelphia ChromosomeCell Transformation, NeoplasticCell DifferentiationTumor Cells, CulturedRNA, MessengerBlast CrisisMutationGreen Fluorescent ProteinsBlotting, WesternCloning, MolecularProtein BindingOncogene Proteins v-ablCell CycleMembrane Fusion ProteinsMice, Inbred C57BLReceptors, Antigen, B-CellDNA-Binding ProteinsLuminescent ProteinsProto-Oncogene ProteinsHematopoietic Stem CellsTranscription FactorsTranslocation, GeneticRecombinant ProteinsGene ExpressionProtein Structure, TertiaryCell SurvivalGene Expression Regulation, LeukemicEscherichia coliReverse Transcriptase Polymerase Chain ReactionLymphocyte ActivationMice, Inbred BALB CMembrane ProteinsDNA PrimersMice, TransgenicFlow CytometryCell Line, TransformedBinding SitesAntineoplastic AgentsGenetic VectorsCell MovementB-LymphocytesTranscription, GeneticGene Expression RegulationT-LymphocytesNuclear ProteinsTime FactorsImmunohistochemistryEnzyme ActivationGene Expression Regulation, NeoplasticChromosomes, Human, Pair 22Mice, KnockoutPlasmidsInterleukin-3Down-RegulationCarrier Proteinssrc Homology DomainsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeGlutathione TransferaseOncogene ProteinsDNATyrosineProtein Kinase InhibitorsSequence Homology, Amino AcidTrans-ActivatorsDose-Response Relationship, DrugSTAT5 Transcription FactorEnzyme InhibitorsNeoplasm ProteinsBone Marrow CellsPhenotypeOncogenes