Tumor MicroenvironmentCell ProliferationCell Line, TumorNeoplasmsCellular MicroenvironmentNeovascularization, PathologicStromal CellsSignal TransductionTumor BurdenTumor Markers, BiologicalMice, Inbred C57BLCell MovementCells, CulturedGene Expression Regulation, NeoplasticTumor EscapeNeoplasm MetastasisLymphocytes, Tumor-InfiltratingNeoplasms, ExperimentalTumor Necrosis Factor-alphaCell HypoxiaMice, NudeMice, Inbred BALB CApoptosisCell DifferentiationImmunohistochemistryCell DivisionCoculture TechniquesTransplantation, HeterologousMice, SCIDBreast NeoplasmsMammary Neoplasms, ExperimentalXenograft Model Antitumor AssaysFibroblastsFlow CytometryDisease ProgressionNeoplasm TransplantationCell SurvivalReverse Transcriptase Polymerase Chain ReactionMelanoma, ExperimentalCell Transformation, NeoplasticMice, TransgenicCell CommunicationAntineoplastic AgentsBrain NeoplasmsRNA, MessengerImmunotherapyMyeloid CellsNeoplasm InvasivenessBlotting, WesternT-LymphocytesModels, BiologicalNeoplasm ProteinsMice, KnockoutGene Expression ProfilingTumor Suppressor Protein p53Cell LineCell Growth ProcessesLymphocyte ActivationCarcinoma, Lewis LungParacrine CommunicationDisease Models, AnimalExtracellular MatrixMammary Neoplasms, AnimalCytokinesOvarian NeoplasmsAntigens, NeoplasmMacrophagesAdenocarcinomaTumor Suppressor ProteinsCell CycleRNA, Small InterferingUp-RegulationAngiogenesis InhibitorsNeoplastic Stem CellsColonic NeoplasmsPancreatic NeoplasmsEpithelial CellsEndothelial CellsGenes, Tumor SuppressorTumor Cells, CulturedTime FactorsGliomaGlioblastomaCancer VaccinesWilms TumorPhenotypeAntibodies, MonoclonalTransfectionCulture Media, ConditionedT-Lymphocytes, RegulatoryCell AdhesionSkin NeoplasmsDown-RegulationDendritic CellsGene ExpressionCD8-Positive T-LymphocytesTransforming Growth Factor betaLiver NeoplasmsLung NeoplasmsMolecular Targeted Therapy