Inflammation MediatorsCytokinesInflammationTumor Necrosis Factor-alphaInterleukin-6Interleukin-1betaInterleukin-1Mice, Inbred C57BLLipopolysaccharidesCells, CulturedNF-kappa BMacrophagesInterleukin-8Mice, KnockoutRNA, MessengerSignal TransductionDisease Models, AnimalInterferon-gammaChemokinesInterleukin-10Gene Expression RegulationMonocytesMice, Inbred BALB CAnti-Inflammatory AgentsLungReverse Transcriptase Polymerase Chain ReactionUp-RegulationToll-Like Receptor 4Cell LineEnzyme-Linked Immunosorbent AssayImmunity, InnateNeutrophilsChemokine CCL2InterleukinsToll-Like ReceptorsGene ExpressionToll-Like Receptor 2Interleukin-17MicrogliaDendritic CellsColitisFlow CytometryNitric Oxide Synthase Type IIMacrophage ActivationBronchoalveolar Lavage FluidMediator ComplexInterleukin-18Biological MarkersMacrophages, PeritonealPneumoniaApoptosisEpithelial CellsT-LymphocytesInterleukin-1alphaTime FactorsTh2 CellsBlotting, WesternMice, TransgenicSynovial MembraneIntercellular Adhesion Molecule-1Interleukin-12Down-RegulationLeukocytes, MononuclearArthritis, RheumatoidImmunohistochemistryRats, Sprague-DawleyReceptors, Interleukin-1Th1 CellsInterleukin-4Neutrophil InfiltrationInterleukin 1 Receptor Antagonist ProteinLeukocytesMyeloid Differentiation Factor 88Anti-Inflammatory Agents, Non-SteroidalArthritis, Experimentalp38 Mitogen-Activated Protein KinasesCyclooxygenase 2Intestinal MucosaMembrane GlycoproteinsLymphocyte ActivationOxidative StressPeroxidaseDose-Response Relationship, DrugC-Reactive ProteinNitric OxideAntigens, CD14I-kappa B ProteinsCD4-Positive T-LymphocytesSepsisEndotoxemiaCoculture TechniquesCaspase 1Antigens, CDTranscription Factor RelAEndotoxinsMacrophages, AlveolarDinoprostoneSpleenRecombinant ProteinsChemokine CXCL2