CytokinesTumor Necrosis Factor-alphaInflammation MediatorsInterleukin-6InflammationInterleukin-1Interleukin-1betaCells, CulturedLipopolysaccharidesMice, Inbred C57BLInterleukin-8Interferon-gammaNF-kappa BMacrophagesRNA, MessengerInterleukin-10Mice, KnockoutChemokinesSignal TransductionMonocytesGene Expression RegulationInterleukinsMice, Inbred BALB CDisease Models, AnimalToll-Like Receptor 4Enzyme-Linked Immunosorbent AssayUp-RegulationReverse Transcriptase Polymerase Chain ReactionCell LineImmunity, InnateToll-Like ReceptorsChemokine CCL2Dendritic CellsInterleukin-4Toll-Like Receptor 2Interleukin-12Interleukin-17Gene ExpressionInterleukin-18Th1 CellsTh2 CellsAnti-Inflammatory AgentsMicrogliaFlow CytometryMacrophages, PeritonealMacrophage ActivationLeukocytes, MononuclearLungT-LymphocytesInterleukin-1alphaNeutrophilsNitric Oxide Synthase Type IIInterleukin 1 Receptor Antagonist ProteinReceptors, Interleukin-1Lymphocyte ActivationEpithelial CellsSynovial MembraneMyeloid Differentiation Factor 88Down-RegulationApoptosisMembrane GlycoproteinsArthritis, RheumatoidBlotting, Westernp38 Mitogen-Activated Protein KinasesCD4-Positive T-LymphocytesAntigens, CD14Granulocyte-Macrophage Colony-Stimulating FactorTime FactorsIntercellular Adhesion Molecule-1Coculture TechniquesMice, TransgenicAntigens, CDNitric OxideSpleenCell DifferentiationInterleukin-13I-kappa B ProteinsRecombinant ProteinsColitisImmunohistochemistryReceptors, CytokineCaspase 1Immunologic FactorsTransforming Growth Factor betaArthritis, ExperimentalBiological MarkersAdjuvants, ImmunologicSepsisInterleukin-2Th17 CellsTranscription Factor RelARats, Sprague-DawleyIntestinal MucosaBronchoalveolar Lavage FluidEndotoxemiaFibroblastsDose-Response Relationship, DrugAnti-Inflammatory Agents, Non-SteroidalEndotoxinsMice, Inbred C3H