• The infiltrative pattern of the mass at the US scan suggested a malignant hepatic neoplasm. (ispub.com)
  • The iron produced in the fluid of endometriotic cysts promotes oxidative stress, which in turn may cause genetic mutations and malignant progression of ovarian cysts. (endometriosi.it)
  • Epithelioid hemangioendothelioma (EHE) is a rare and slow-growing malignant vascular neoplasm composed of epithelioid endothelial cells within a distinctive myxohyaline stroma. (springeropen.com)
  • These insights, in turn, have prompted novel, testable hypotheses, to be discussed, pertaining to fundamental aspects of cancer biology including the potential stem cell/progenitor cell origins of cancer and the plasticity of gene expression that may underlie tumor heterogeneity and tumor progression. (esmed.org)
  • MC participate in detection of harmful pathogens like viruses, bacteria, parasites and toxins, play the role in wound healing, cancer and tumor progression. (encyclopedia.pub)
  • Twenty-one patients (42%) received SRS (median 18 Gy), and 7 (33%) had tumor progression. (elsevierpure.com)
  • Twenty-nine patients (58%) received EBRT (median 54 Gy), and 13 (45%) had tumor progression. (elsevierpure.com)
  • Compared with previously used Markov models for tumor progression, the applied model gave considerably higher model fit (85% increased predictive power) and provided estimates directly linked to tumor size. (biomedcentral.com)
  • Tumor growth can also be indirectly observed as tumor progression, estimated from variations in cancer incidence in screening trials or programs. (biomedcentral.com)
  • Immunohistochemical and immunoelectron study of major histocompatibility complex class-II antigen in canine cutaneous histiocytoma: its relation to tumor regression. (illumina.com)
  • Histiocytic sarcoma Localized histiocytic sarcoma Diffuse histiocytic sarcoma Histiocytoma is a common, benign, cutaneous neoplasm in dogs. (wikipedia.org)
  • These workers are also at increased risk for cutaneous neoplasms, with an odds ratio (OR) of 3.67 for cSCCs, 3.32 for basal cell carcinoma (BCC), and 1.97 for melanoma. (medicalacademic.co.za)
  • Delayed regression of multiple histiocytomas can occur and lesions can persist for up to 10 months. (wikipedia.org)
  • In 3 instances regression of these lesions occurred spontaneously within 3-4 weeks. (wikipedia.org)
  • As previously described in a prior paper by the same authors ( 1 ), the inflammatory pseudotumor of the liver is a heterogeneous group of disease, a complex of lesions of unknown aetiology and pathogenesis which occupy space and mimic a neoplasm. (ispub.com)
  • Spontaneous regression: In 20% to 23% of patients with a single lesion, and in up to 7.2% of patients with field cancerisation (presence of multiple AKs surrounded by an area of photodamaged skin) lesions may disappear spontaneously. (medicalacademic.co.za)
  • All lesions should be treated because predicting the progression of AKs is challenging. (medicalacademic.co.za)
  • What is known is that patients with numerous lesions are at increased risk of progression to cSCCs. (medicalacademic.co.za)
  • METHODS: Fifty radiation-naive patients who received SRS or EBRT for residual and/or recurrent atypical meningioma were examined for predictors of progression using Cox regression and Kaplan-Meier analyses. (elsevierpure.com)
  • A 61-year-old man had been referred to the Department of Hepatobiliary and Pancreatic Surgery of our hospital for multiple hepatic giant hemangiomas with no significant progression, 5 years before his first visit to our department. (springeropen.com)
  • Although the classic presentation of BIA-ALCL is known as late persistent seroma, an atypical manifestation such as spontaneous resorption may occur, as in the current case. (e-aaps.org)
  • The progression of liver injury to cirrhosis may occur over several weeks to years. (medscape.com)
  • The clinical course of patients with neuroblastoma is highly variable, ranging from spontaneous regression to widespread metastatic disease. (biomedcentral.com)
  • Renal cell carcinoma is an immunogenic tumor, and spontaneous regressions have been documented. (medscape.com)
  • 3 Energy restriction limited to very early life has been shown to result in reduced risk of cancer, 4 and delays in both onset and progression of cancer have been found. (bmj.com)
  • In secondary echinococcosis, larval tissue spreads from the primary site and new cysts develop after spontaneous or trauma-induced cyst rupture or after release of viable parasite material during invasive treatment procedures. (cdc.gov)
  • Invasive and preinvasive neoplasms of the vulva may be HPV-induced, and the carcinogenic effect may be widespread in the vulvar epithelium. (cancer.gov)
  • Neurofibromatosis 1 is an autosomally dominated inherited genetic condition that predisposes those involved to the development of intracranial neoplasms. (medlink.com)
  • Spontaneous regression has been reported in as many as 15% of patients with cervicofacial lymphangioma. (medscape.com)
  • Whether patients with this neoplasm present in childhood or adulthood, the identification of a mass requires a diagnosis and management plan. (medscape.com)
  • only 2 patients required surgical intervention for local progression or symptoms. (medscape.com)
  • Around 25% of patients with PC-ALCL show spontaneous regression. (medscape.com)
  • RESULTS: Thirty-two patients (64%) received adjuvant radiation after subtotal resection, 12 patients (24%) received salvage radiation after progression following subtotal resection, and 6 patients (12%) received salvage radiation after recurrence following gross total resection. (elsevierpure.com)
  • Patients who present with effusion or seroma (70%) and/or distinct mass formations (30%), as well as patients with breast masses, showed worse overall survival and progression-free survival [ 7 ]. (e-aaps.org)
  • Type 1 burning mouth syndrome (BMS): Patients have no symptoms upon waking, with progression throughout the day. (medscape.com)
  • We were also able to define immunogenic membrane proteins from lung (squamous and adenoCa) as well as prostate neoplasms. (jcancer.org)
  • OBJECTIVE: To analyze features associated with progression after radiation therapy. (elsevierpure.com)
  • IARC at the World Health Organization (WHO) is independently financed and has its own governing and scientific councils, which WHO staff only attend as observers ( http://www.who.int/ionizing_radiation/research/iarc/en/ ). (spandidos-publications.com)
  • Stage Ms tumors (where 's' stands for special and meta-static disease is confined to skin, liver and/or bone marrow) are characterized by spontaneous regression or differentiation even without any form of therapy. (biomedcentral.com)
  • Non-Hodgkin's lymphomas represent the most common ocular adnexa neoplasm [ 1 ]. (biomedcentral.com)
  • Lymphatic malformation or lymphangioma is a rare neoplasm or congenital rest that presents in the head and neck region in more than 70% of cases. (medscape.com)
  • Weiss and Enzinger first reported epithelioid hemangioendothelioma (EHE) in 1982 as a rare vascular endothelial neoplasm arising in soft tissues [ 1 ]. (springeropen.com)
  • The growth rate of this neoplasm is variable. (medscape.com)
  • The postoperative major morbidity and cancer-specific survival (CSS) of the two groups were compared and the independent factors that were associated with the two study endpoints were identified by multivariable regression analysis. (bvsalud.org)
  • The primary goal of field-directed treatments is to reduce the risk of progression to cSCCs. (medicalacademic.co.za)
  • We report a case of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), which had a history of spontaneous resorption of late seroma before diagnosis. (e-aaps.org)
  • MALT-lymphomas often recognize specific environmental factors responsible of lymphoma development and progression. (biomedcentral.com)
  • A study of lung cancer patients found significantly higher 5-year survival rates and tumor regression rates in those who received melatonin each evening while undergoing chemotherapy compared with those who received chemotherapy alone. (lifeextension.com)
  • Renal cell cancer is one of the few tumors in which well-documented cases of spontaneous tumor regression in the absence of therapy exist, but this regression occurs rarely and may not lead to long-term survival. (cancer.gov)
  • Therefore, the identification of hypoxia-inducible protein targets responsible for cancer progression, malignant transformation and metastasis is needed for deepening our understanding of OS biology. (nature.com)
  • Both clinical and experimental studies indicate that many or most malignancies will ultimately progress if VEGF blockade is sustained, and that progression may involve both progressive primary tumor growth and enhanced metastasis. (biomedcentral.com)
  • Prior work demonstrates that the celecoxib analog SC236 can reduce spontaneous and experimental metastasis, although it is not clear whether this is due to effects on individual tumor cells, on the primary tumor (e.g. angiogenesis), or on the host environment [ 13 ]. (biomedcentral.com)
  • Thus, it is not known whether the addition of SC236 would limit spontaneous lung metastasis in hypoperfused tumors as occurs during VEGF blockade, when primary tumor angiogenesis is restricted but other prometastatic mechanisms may be active. (biomedcentral.com)
  • Neoplasms cause hypercalcaemia either by direct invasion (metastasis) or through factors that stimulate osteoclasts (Parathyroid hormone related peptide or PTHrP). (sath.nhs.uk)
  • 90% of cases JMML is driven by germline or somatic mutations involving the canonical RAS pathway (PTPN11, NRAS, CBL, KRAS and NF1), with somatic mutations/alterations in RAS pathway genes (second hit), SETBP1, ASXL1 and JAK3 resulting in disease progression. (nih.gov)
  • pCMML largely occurs due to RAS pathway mutations that occur in the context of age related clonal hematopoiesis (TET2, SRSF2, ASXL1), while JMML is a bona fide RASopathy, with additional somatic mutations, including in epigenetic regulators genes resulting in disease progression. (nih.gov)
  • Mechanisms of progression have been proposed to include genes that control vascular remodeling and are elicited by hypoperfusion, such as the inducible enzyme cyclooxygenase-2 (COX-2). (biomedcentral.com)
  • It is a rare disease accounting for 3% of all soft tissue neoplasms, with an incidence of 2-5 people per million per year [ 1 ]. (biomedcentral.com)
  • These ovarian neoplasms are generally classified as epithelial, germ cell, or sex cord-stromal tumors. (nih.gov)
  • 17. c-KIT is frequently mutated in bilateral germ cell tumours and down-regulated during progression from intratubular germ cell neoplasia to seminoma. (nih.gov)
  • 18. Spontaneous regression of testicular germ cell tumors: an analysis of 42 cases. (nih.gov)
  • 19. [Intratubular neoplasm adjacent to germ cell tumor of the testis]. (nih.gov)
  • The estimated local progression free survival of the treated lesion in 3 and 5 years was 76.4% and 63,8%, respectively. (biomedcentral.com)
  • The progression-free survival in 3 and 5 years was 72.3 and 58.4% and the overall survival was 97.4 and 97.4%, respectively. (biomedcentral.com)
  • In univariate analysis multifocal localization was associated with impaired progression-free survival ( p = 0.013). (biomedcentral.com)
  • Tyrosine kinase inhibitor (TKI) therapy has recently been demonstrated to increase progression-free survival in these patients but poses some unique management issues and is best used as part of an integrated approach with directed therapy. (bioscientifica.com)
  • A Multi-state Model for Designing Clinical Trials for Testing Overall Survival Allowing for Crossover after Progression. (unc.edu)
  • The growth rate of this neoplasm is variable. (medscape.com)
  • The course of the disease is variable and unpredictable including growth, progression, stabilization, and even spontaneous regression [ 4 ]. (biomedcentral.com)
  • Vascular endothelial growth factor (VEGF) blockade is an effective therapy for human cancer, yet virtually all neoplasms resume primary tumor growth or metastasize during therapy. (biomedcentral.com)
  • We used LASSO algorithm and multiple-cox regression to establish a programmed cell death-associated gene prognostic model. (cdc.gov)
  • Multiple Cox regression stratified by age group coded as binary (65 and under, and over 65) of the undetectable hepatitis C viral fill. (techieindex.net)
  • Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions. (lookformedical.com)
  • A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. (lookformedical.com)
  • Macrophages in the B-cell lymphoma microenvironment represent a functional node in progression and therapeutic response. (sfb1530.de)
  • They represent focal areas of abnormal keratinocyte proliferation and differentiation that carry a relatively low risk of progression to invasive squamous cell carcinoma (SCC). (medscape.com)
  • External factors such as immunosuppression (weakening of the immune system) or smoking as well as internal factors such as genetic predisposition promote the progression of the disease to the point of developing uterine cancer. (medicinelearners.com)
  • A spontaneous diminution or abatement of a disease over time, without formal treatment. (nih.gov)
  • Histiocytic sarcoma Localized histiocytic sarcoma Diffuse histiocytic sarcoma Histiocytoma is a common, benign, cutaneous neoplasm in dogs. (wikipedia.org)
  • Cadaveric specimens from 6 neurologically normal dogs and 2 dogs with vertebral neoplasms that extended into the epidural space and MRI sequences and cytologic preparations from 2 dogs with compressive hydrated nucleus pulposus extrusion that underwent decompressive surgery. (avma.org)
  • In order to clarify the mode of action of acrylamide induced neoplasms, we sought out a strain of rats which did not get Leydig cell tumors and had a low level of background TVMs to examine a potential endocrine mode of action. (gpstoxpath.com)
  • Separate categories are reserved for neoplasms composed of cells of several origins and for nonneoplastic disorders that simulate neoplasms. (nih.gov)
  • A CT scan was performed and revealed mediastinal, abdominal, and retroperitoneal lymphadenopathy, that, compared to the CT results 6 years ago, when for the first time enlarged lymph nodes were discovered by thyroid ultrasound, was without any progression. (bvsalud.org)
  • Juvenile myelomonocytic leukemia (JMML) is a pediatric myelodysplastic/myeloproliferative neoplasm overlap syndrome with sustained peripheral blood monocytosis, aggressive features, and poor outcomes. (nih.gov)
  • If there is no regression in the next few months, the tissue is removed. (medicinelearners.com)
  • Follow-up CT scan three months after commencement of sorafenib revealed regression of pulmonary metastases but no evident change in most bone metastases except for an advancing lesion eroding into the right acetabulum. (bioscientifica.com)