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  • synthesis
  • Furthermore, local perivascular application of the potent and selective arginase inhibitors S -(2-boronoethyl)- l -cysteine (BEC) or N G -hydroxy-nor- l -arginine (L-OHNA) immediately after injury markedly attenuated medial and neointimal DNA synthesis and neointima formation. (ahajournals.org)
  • inhibitor
  • A subsequent phase I trial in humans failed to show an increase in the tolerated dose of IL-2, although indications of pharmacological activity as an inhibitor of tumor necrosis factor production were observed. (wikipedia.org)
  • ammonia
  • In addition, arginine supplementation could decrease accumulations of lactate and ammonia, metabolites involved in development of muscular fatigue. (blogspot.com)
  • The results of this study suggested that short-term arginine supplementation had no effect on nitric oxide production, lactate and ammonia metabolism and performance in intermittent anaerobic exercise in well-trained male athletes. (blogspot.com)
  • Low protein diets, are intended to minimize production of ammonia. (wikipedia.org)
  • Arginine, sodium benzoate and sodium phenylacetate help to remove ammonia from the blood. (wikipedia.org)
  • Arginine plays an important role in cell division, wound healing, removing ammonia from the body, immune function, and the release of hormones. (wikipedia.org)
  • mutagenesis
  • Although there is no consensus of the catalytic acid that donates the proton to the imine functional group of the arginine product, some mutagenesis studies show serine 283 may be involved. (wikipedia.org)
  • epithelial cells
  • Background: Previously we showed that reduced availability of the essential amino acid tryptophan per se attenuates post-transcriptional control of interleukin (IL)-6 and IL-8 leading to hyperresponsive production of these inflammatory mediators by airway epithelial cells. (uva.nl)
  • Conclusion: We conclude that both reduced arginine availability per se and the presence of polycationic proteins may promote airway inflammation by enhanced pro-inflammatory mediator production in airway epithelial cells, but due to distinct mechanisms. (uva.nl)
  • inhibition
  • Instead, Akt activity is increased to phosphorylate the eNOST495 inhibition site, downregulating eNOS production of NO. H2S therapy uses a H2S donor, such as diallyl trisulfide (DATS), to increase the supply of H2S to an AMI patient. (wikipedia.org)
  • occurs
  • Thus a spiralling effect occurs with high endothelial LDL levels causing greater ADMA values, which in turn inhibit NO production needed to promote vasodilation. (wikipedia.org)
  • renal
  • These receptors also cause a renal vasodilation, resulting in increase of the water amount in the glomerular filtrate which, combined with the increased production of vasopressin by the hypothalamus, will cause water retention in urine. (wikipedia.org)
  • growth
  • On the other hand, culture growth is affected by Arg and Gly in a similar way to CYN production, with Arg stimulating and Gly impairing it. (mdpi.com)
  • Major factors driving growth of this market include the application of biological fermentation technology, which enabled the production of arginine improved a lot, rising care awareness and increasing disposable income in emerging economies, However, high cost of instruments, lack of production technology especially in emerging economies, and lack of laboratory technicians are expected to restrain the growth of this market. (reportsnreports.com)
  • CP production is influenced by culture medium and growth phase. (wikipedia.org)
  • endothelial
  • l -Arginine transport by both bovine aortic smooth muscle cells (BASMCs) and endothelial cells (BAECs) was primarily Na + independent (≈70%) and was mediated by both a high- and low-affinity transport system. (ahajournals.org)
  • Arginine supplementation has been shown to alleviate endothelial dysfunction and improve exercise performance through increasing nitric oxide production in patients with cardiopulmonary diseases. (blogspot.com)
  • carbon
  • A method of producing arginine bicarbonate is provided including reacting an arginine slurry with a source of carbon dioxide gas under elevated temperature and low pressure to form a solution of at least 50% arginine bicarbonate, and recovering arginine bicarbonate from the solution. (google.com)
  • Arginine bicarbonate may be produced by bubbling carbon dioxide gas through a saturated arginine aqueous solution at room temperature and pressure. (google.com)
  • No. 6,217,851 describes preparing arginine bicarbonate from arginine hydroxide by bubbling carbon dioxide or by adding dry ice in excess into a solution of arginine free base. (google.com)
  • study
  • 5 Since NO generation by vascular smooth muscle and by endothelium has contrasting requirements for extracellular l -arginine, the present study directly compared l -arginine transport by these different cell types cultured from the same vascular source, specifically BASMCs and BAECs. (ahajournals.org)
  • The aim of this study was to investigate the effect of short-term arginine supplementation on performance in intermittent anaerobic exercise and the underlying mechanism in well-trained male athletes. (blogspot.com)
  • The worldwide market for L-Arginine is expected to grow at a CAGR of roughly 7.6% over the next five years, will reach 760 million US$ in 2023, from 490 million US$ in 2017, according to a new GIR (Global Info Research) study. (reportsnreports.com)
  • anaerobic
  • The subjects consumed 6 g/day arginine (ARG trial) or placebo (CON trial) for 3 days then performed an intermittent anaerobic exercise test on a cycle ergometer. (blogspot.com)
  • It was originally thought that the energy for swimming was supplied aerobically through respiration with little input from anaerobic glycolysis and arginine phosphate. (wikipedia.org)
  • synthesis
  • Furthermore, local perivascular application of the potent and selective arginase inhibitors S -(2-boronoethyl)- l -cysteine (BEC) or N G -hydroxy-nor- l -arginine (L-OHNA) immediately after injury markedly attenuated medial and neointimal DNA synthesis and neointima formation. (ahajournals.org)
  • tumor
  • L-arginine enhances nitrative stress and exacerbates tumor necrosis factor- α toxicity to human endothelial cells in culture: prevention by propofol," Journal of Cardiovascular Pharmacology , vol. 55, no. 4, pp. 358-367, 2010. (hindawi.com)
  • Evidence also suggests that CD8 T lymphocyte cells mediate protection against Yersinia by production of cytokines (e.g., tumor necrosis factor alpha [TNF-alpha] and gamma interferon [IFN]) and by killing bacteria-associated host cells to promote internalization by neighbouring phagocytes. (wikipedia.org)
  • found
  • been and found separate conformations and moved deserts and men for & lying with the production and bonitate of possible Base creation fables. (sftv.org)
  • Although "H. salinarum" is unable to catabolize glucose, the transcription factor TrmB has been proven to regulate the gluconeogenic production of sugars found on the S-layer glycoprotein. (wikipedia.org)
  • heart
  • Supplemental arginine has been proposed as a treatment for various conditions, including heart problems. (oakhillhospital.com)
  • Agmatine produces mild reductions in heart rate and blood pressure, apparently by activating both central and peripheral control systems via modulation of several of its molecular targets including: imidazoline receptors subtypes, norepinephrine release and NO production. (wikipedia.org)
  • thus
  • The basic region is involved in RNA (TAR, trans-activation response element) binding and Tat proteins thus belong to the family of arginine-rich motif (ARM) RNA binding proteins. (wikipedia.org)
  • Function
  • 6 A recent study has provided evidence that a subset of glutamate receptors, involved in the function of the afferent arm of the baroreceptor reflex, may be coupled with heme oxygenase-mediated production of carbon monoxide. (ahajournals.org)