• These two modifications combined were synergistic, resulting in a 10-fold improvement in potency against Pneumocystis jirovecii (formerly known as Pneumocystis carinii) pneumonia. (wikipedia.org)
  • Alternative for treatment and prevention of Pneumocystis jirovecii (formerly Pneumocystis carinii ) pneumonia (PCP) in adults, adolescents, or children † [off-label] who cannot tolerate co-trimoxazole. (drugs.com)
  • hominis ) is an opportunistic fungus that causes Pneumocystis pneumonia (PCP) in immunocompromised individuals. (biomedcentral.com)
  • To investigate the clinical importance of a positive Pneumocystis -PCR among HIV-uninfected patients suspected of bacterial pneumonia, a retrospective matched case-control study was conducted. (biomedcentral.com)
  • Respiratory samples from 367 patients suspected of bacterial pneumonia were analysed by PCR amplification of Pneumocystis jiroveci . (biomedcentral.com)
  • Pneumocystis pneumonia (PCP) is a common and serious opportunistic infection in immunocompromised patients that is caused by the fungal pathogen Pneumocystis jiroveci , formerly known as P. carinii f.sp. (biomedcentral.com)
  • Recommendations are given for preventing cytomegalovirus disease with prophylactic or preemptive gancyclovir, herpes simplex virus disease with prophylactic acyclovir, candidiasis with fluconazole, and Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole. (cdc.gov)
  • Most commonly, it is the result of infections (bacterial, viral, or fungal), but it can occur as a result of chemical injury (gastric acid/aspiration of food/hydrocarbon and lipoid pneumonia/radiation-induced pneumonia). (pediatriconcall.com)
  • Staphylococcal pneumonia, although rare, can be very serious despite treatment. (pediatriconcall.com)
  • A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. (drugbank.com)
  • Tuberculosis (TB) was the commonest OI (71%) followed by candidiasis (39.3%), Pneumocystis jiroveci pneumonia (PCP) (7.4%), cryptococcal meningitis and cerebral toxoplasmosis (3.7% each). (biomedcentral.com)
  • Pneumocystis Carinii Pneumonia (P.C.P.) - a infection that can cause a deadly form of pneumonia. (homehealth-uk.com)
  • This is a very important activity since there is an increase in the frequency of fungal infections, accompanied by an increase in the variety of opportunistic and pathogenic fungi such as Candida. (wikipedia.org)
  • Caspofungin represents an interesting and clinically valuable new antifungal drug that broadens the available therapeutic armamentarium for the treatment of invasive fungal infections. (wikipedia.org)
  • Hospitalization is necessary in patients with acute myeloid leukemia for managing chemotherapy and for treating complications related to the disease and its treatment, usually infections or febrile neutropenic episodes. (medscape.com)
  • Patients have extreme susceptibility to bacterial, viral, and fungal infections in the first year of life and usually results in death by age of four. (lu.se)
  • Other recommendations include treatment of infections with antibacterials, antifungals, and antivirals, intravenous gamma-globulin infusion, irradiation of all blood products. (lu.se)
  • Compounds having both anticancer and antimicrobial activity have promising therapeutic potential due to their selective cytotoxicity and their potential to reduce the occurrence of bacterial and fungal infections in immune-compromised cancer patients. (biomedcentral.com)
  • fungal, bacterial and malarial infections, as well as malnutrition caused heavy mortality in a group of wild-trapped canvasbacks (aythya valisineria) held in 10 x 3 x 2 m open-water pens. (liverpool.ac.uk)
  • The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation. (acciusa.com)
  • Grifulvin V is an antifungal medication that is used to treat fungal infections of the skin, nails, and hair. (antibioticsbuying.com)
  • By detecting it early, people with HIV infection can discuss with their doctor when they should start treatment to help their immune systems combat HIV and help prevent the emergence of opportunistic infections. (digitalnaturopath.com)
  • Timely initiation of prophylaxis for opportunistic infections (OIs) and their prompt recognition and treatment are the only economically viable options [ 6 ]. (biomedcentral.com)
  • Oftentimes, this population cultivate and transplant wild medicinal plants in and around their homes and villages that are employed to treat common fevers, fungal infections, respiratory problems, pain, gastrointestinal problems and even antidotes for poisonous snake bites, among many others health problems they are faced with. (rain-tree.com)
  • Keywords: STIs, Treatment [IS-02] The epidemiology, pathogenesis, and diagnosis of vulvovaginal candidosis Macit Ilkit Macit Ilkit Background: Materials-Methods: Results: Conclusion: Vulvovaginal candidosis (VVC) is the second most common cause of vaginitis (17-39%) after bacterial vaginosis (22-50%), in terms of vaginal complaints in the primary care setting. (paperzz.com)
  • Trimex PS is also used to prevent & treat infection caused by a parasite (toxoplasmosis) and lung infection caused by the fungus (Pneumocystis jiroveci pneumonitis). (co.ke)
  • Alternative for treatment or prevention of toxoplasmosis † [off-label] caused by Toxoplasma gondii . (drugs.com)
  • Roxithromycin is absorbed well into the gastro-intestinal tract, with few side effects, and actively responds to the presence of cryptosporidium, pneumocystis carinii (PCP), toxoplasma gondii, and Mycobacterium Avium (MAC). (canadianepharmacy.com)
  • Atovaquone in conjunction with pyrimethamine (and leucovorin), atovaquone in conjunction with sulfadiazine, or atovaquone alone are alternative regimens for treatment of toxoplasmosis † [off-label] in HIV-infected adults and adolescents when regimen of choice and preferred alternative cannot be used. (drugs.com)
  • The signs and symptoms of histoplasmosis, a chronic systemic fungal infection, resemble those of tuberculosis. (rnpedia.com)
  • Designated an orphan drug by FDA for treatment of PCP associated with acquired immunodeficiency syndrome (AIDS) and prevention of PCP in high-risk HIV-infected patients (i.e., history of ≥1 episode of PCP and/or CD4 + T-cell counts ≤200/mm 2 ). (drugs.com)
  • Although efficacy and safety not established in pediatric patients and data limited regarding use in children, CDC, NIH, IDSA, and AAP state atovaquone also can be considered an alternative for treatment of mild to moderate PCP in HIV-infected children † [off-label] when co-trimoxazole cannot be used. (drugs.com)
  • Despite significant improvements in the treatment of Hodgkin's lymphoma over the past 2 decades, physicians continue to face dilemmas in therapy for the disease, and many cured patients live with complications of treatment. (cancernetwork.com)
  • Newer therapeutic options are still needed for the disease, to minimize complications and to improve the treatment of patients in relapse. (cancernetwork.com)
  • This review considers the treatment of Hodgkin's lymphoma in younger patients, addressing such issues as which patients with early-stage disease may require radiotherapy, what prognostic factors provide information that can affect treatment choices in patients with advanced disease, and what we have learned about treatment complications in this setting. (cancernetwork.com)
  • Still, physicians face dilemmas in therapy for the disease, and many cured patients live with complications of treatment. (cancernetwork.com)
  • In this review, we consider the treatment of HL in younger patients, first evaluating recent clinical trials for early-stage disease, with a special focus on which patients may still need radiotherapy (RT). (cancernetwork.com)
  • Treatment for patients with acute myeloid leukemia involves intensive chemotherapy to destroy the leukemic cell population as rapidly as possible and to prevent the emergence of a resistant clone. (medscape.com)
  • In September 2017, the FDA approved gemtuzumab ozogamicin (Mylotarg) for the treatment of relapsed or refractory CD33-positive AML in patients aged 2 years and older. (medscape.com)
  • Gemtuzumab ozogamicin originally received accelerated approval in May 2000 as a stand-alone treatment for relapsed CD33-positive AML in older patients, but was voluntarily withdrawn from the market after subsequent confirmatory trials failed to verify clinical benefit and demonstrated safety concerns, including a high number of early deaths. (medscape.com)
  • Pneumocystis-DNA was detected in 16 (4.4%) of patients. (biomedcentral.com)
  • Detection of Pneumocystis-DNA was associated with a worse prognosis: seven (44%) of patients with positive PCR died within one month compared to nine (14%) of the controls (p = 0.01). (biomedcentral.com)
  • Further studies of P. jiroveci in patients receiving systemic treatment with corticosteroids are warranted. (biomedcentral.com)
  • In particular, the ability to subset patients more accurately has improved triage of treatments. (ashpublications.org)
  • The first section emphasizes examples bearing on how the rapidly evolving array of diagnostic tests and epidemiologic information might best be incorporated into caring for individual patients while the second provides a brief summary of general trends in treatment. (ashpublications.org)
  • Here, we asked whether periodontitis is worsened in patients under antihypertensive treatment with ACE inhibitors. (bvsalud.org)
  • Decision to admit was taken by the treating physician and all patients were hospitalised for the evaluation and treatment of a suspected OI or HIV-related disorder. (biomedcentral.com)
  • treatment can restore immune function in most patients if suppression of replication is sustained. (msdmanuals.com)
  • in vaginal swabs using vaginal pH measurement, microscopic examination, fungal culture, and antigen tests. (paperzz.com)
  • liver disease due to hepatitis C coinfection or hepatitis B coinfection, HIV-associated biliary tract disease, or cholangiopathy due to pneumocystis, cryptosporidiosis, cytomegalovirus, or Mycobacterium avium complex. (pcrm.org)
  • For advanced disease, prognostic factors may provide information for those wishing to use treatment other than the ABVD regimen (Table 1) or other standard chemotherapy regimens. (cancernetwork.com)
  • The International Berlin-Frankfurt-Münster (BFM) Study Group reported that children with relapsed AML who received liposomal daunorubicin (DNX) in conjunction with the FLAG regimen (fludarabine, cytarabine, and granulocyte colony-stimulating factor [G-CSF]) had improved early treatment response. (medscape.com)
  • This antifungal agent attacks the fungal cell by selective inhibition of β-(1→3)-D-glucan synthase, which is not present in mammalian cells. (wikipedia.org)
  • Before effective treatments AIDS was a state someone infected with HIV almost inevitably entered, as HIV attacked their immune system. (homehealth-uk.com)
  • Transfer to a pediatric cancer center is usually necessary for initial diagnostic studies and is mandatory for management of chemotherapy and treatment-related complications. (medscape.com)
  • Immunosuppression is a major complication in cancer and also an adverse effect of chemotherapy during the treatment of cancer. (biomedcentral.com)
  • Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer. (drugbank.com)
  • After transplantation, most febrile episodes require in-patient treatment and observation until profound neutropenia and clinically significant infection resolves. (medscape.com)
  • In children who have recurrent or chronic symptoms, further testing including skin testing to identify fungal pathogens, sweat chloride estimation to identify Cystic fibrosis, titers against rare organisms, and bronchoscopy may be required. (pediatriconcall.com)
  • A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. (drugbank.com)
  • For the treatment of chronic obstructive pulmonary disease. (drugbank.com)
  • Investigated for use/treatment in inflammatory disorders (unspecified), knee replacement, orthopedic surgery, and pain (acute or chronic). (drugbank.com)
  • Improved diagnosis and longer survival have fostered an understanding of the multidisciplinary approach necessary to manage both the underlying problems and the significant sequelae of treatment in both acquired and congenital disease. (ashpublications.org)
  • Without treatment, it usually takes about 10 years for someone with HIV to develop AIDS. (hivtalk.net)
  • Most scientists and doctors are convinced that if we follow up infected people for long enough---maybe for twenty to thirty years or more if they are getting good treatment---then all or nearly all will die of AIDS, unless they have died of something else in the meantime such as a heart attack or cancer. (globalchange.com)
  • See "Adenosine deaminase deficiency: Treatment and prognosis" and "Purine nucleoside phosphorylase deficiency" . (medilib.ir)
  • rare hereditary diseases, hazardous environmental conditions, unusual toxic exposures, or unsafe consumer products may only be suspected or identified after a complete, detailed and through autopsy rules out more likely causes. (medscape.com)
  • Atovaquone used alone is one of several alternatives recommended by CDC, NIH, and IDSA for treatment of mild to moderate PCP in HIV-infected adults and adolescents when co-trimoxazole cannot be used. (drugs.com)
  • Hodgkin's lymphoma (HL) is a rare, curable malignancy, and investigators have made remarkable improvements in treatment of the disease over the past 20 years. (cancernetwork.com)
  • Recent trials suggest that ABVD or variants of this combination with or without RT may still be the best therapy for early-stage HL, regardless of the type of disease presentation, and the potential for complications of therapy may ultimately direct choices of treatment. (cancernetwork.com)
  • Although these treatments prolonged pancytopenia, they decreased induction failures and substantially improved disease-free survival. (medscape.com)
  • Our data suggest that carriage of Pneumocystis jiroveci is associated with old age, concurrent disease and steroid treatment. (biomedcentral.com)
  • Longitudinal data from large cohort studies and disease registries are providing a rational basis for making more informed treatment decisions for children with these disorders. (ashpublications.org)
  • In particular syphilis treatment was long and by modern standards horrific but despite that still was a common disease. (paperzz.com)
  • Optimal treatment regimens in men and women require additional evaluation using newer diagnostic tests to define therapeutic endpoints. (paperzz.com)
  • Treatment slows down the damage the virus causes and can help people stay healthy for several decades. (hivtalk.net)
  • He also is the author of two books: How Everyday Products Make People Sick (University of California Press, 2009) and Fake Silk: The Lethal History of Viscose Rayon (Yale University Press, 2016). (ucsf.edu)
  • Among people living with HIV in 2021, approximately 85% knew their HIV status and 75% were accessing treatment. (msdmanuals.com)
  • Designated an orphan drug by FDA for primary prophylaxis in HIV-infected individuals at high risk for developing T. gondii encephalitis and for treatment and suppression of T. gondii encephalitis. (drugs.com)
  • TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. (drugbank.com)
  • in rats c3 depletion by treatment of animals with the c3 inactivator isolated from cobra venom factor results in infection that develops more rapidly, reaches a higher peak of parasitemia and is associated with an increased mortality rate (60%), in contrast to a lower degree of parasitemia and lack of mortality in c3-intact rats. (liverpool.ac.uk)
  • IS-01] Treatment of STIs in the pre-antibiotic era Michael Anthony Waugh Nuffield Hospital Leeds Background: Invited Speaker -President IUSTI 1995-1999 Materials-Methods: Recognised Authority on History of Venereology Results: A Precise history of Treatment before antibiotics A concise account is given from Roman times, through Arab medicine and Europe before the Scientific Revolution of 19th. (paperzz.com)
  • Bactrim sulfamethoxazole and trimethoprim) is a synthetic antibacterial combination product available in DS (double strength) and SS (single strength) tablets, in oral suspension and in injectable form. (antibioticsbuying.com)
  • This product is available in the following dosage forms: Tablet Suspension Injection Powder for Solution DS Tablet SS Tablet Oral Suspension Injectable Suspension Side Effects Dosage Interactions Pregnancy More For the Consumer Applies to sulfamethoxazole / trimethoprim: oral suspension, oral tablet, oral tablet chewable, oral tablet extended release Other dosage forms: intravenous solution Side effects requiring immediate medical attention Along with its needed effects, sulfamethoxazole / trimethoprim may cause some unwanted effects. (antibioticsbuying.com)
  • Co-trimoxazole is drug of choice for treatment of mild, moderate, or severe PCP in adults, adolescents, and children, including HIV-infected individuals. (drugs.com)
  • Hill: I have a Ph.D. in microbiology from the University of Arkansas, and my graduate background is in research on fungal physiology. (nih.gov)
  • It also shouldn't suggest that these plants are more effective or suitable to treat these conditions than other westernized drugs or products which might be available here in the U.S. but not available in the countries where these plants grow and where their history of medicinal use has been recorded. (rain-tree.com)
  • A herbal supplement found in over-the-counter or unapproved homeopathic products for various health conditions, such as cognitive, neurodegenerative, cardiovascular, and reproductive health disorders. (drugbank.com)
  • not included in recommendations for treatment of severe PCP. (drugs.com)
  • citation needed] In the wild-type strain, pneumocandin B0 is a minor fermentation product, and its industrial production was achieved by a combination of extensive mutation and medium optimization. (wikipedia.org)
  • I have not had occasion to buy the product in question for many years, so I made a point of examining its packaging and the claims made for it. (parliament.uk)
  • citation needed] Compounds with this fungal-specific target have several attractive features: Lack of mechanism-based toxicity Potential for fungicidal activity Activity against strains with intrinsic or acquired resistance mechanisms for existing antimycotics. (wikipedia.org)