• pathologies
  • For several decades, it has been known that CR, when started in many strains of young or middle-aged rodents and maintained thereafter, extends maximum and average life span by as much as 40% and delays many age-related changes and pathologies such as kidney disease, diabetes, several types of tumors, and declines in immune function. (nih.gov)
  • Targeting cancer prevention pathways with anti-cancer agents may confer longevity effects by offering protection from metabolic pathologies during aging, independently of effects on cancer. (wikipedia.org)
  • mechanisms
  • According to the standard information-processing model for mental development, the mind's machinery includes attention mechanisms for bringing information in, working memory for actively manipulating information, and long term memory for passively holding information so that it can be used in the future. (wikipedia.org)
  • The neurological mechanisms responsible for face recognition are present by age five. (wikipedia.org)
  • Disease
  • According to research, a bland job which doesn't excite you or where you have to work overtime raises your risk of getting a heart disease and makes your body to age sooner. (onlymyhealth.com)
  • Though the effects of sustained CR on life span in nonhuman primates are not yet known, CR in monkeys has favorable effects on risk factors for diabetes and cardiovascular disease. (nih.gov)
  • That they were not may be due to factors such as the great length of time needed, the amount of support required, the complications of disease or accidental deaths in the animal colony, and the experimental error that can plague long-term research. (springer.com)
  • Many of the disease processes, such as testicular torsion, epididymo-orchitis, and intratesticular tumor, produce the common symptom of pain at presentation, and differentiation of these conditions and disorders is important for determining the appropriate treatment. (wikipedia.org)
  • secondary
  • The research data clearly indicate that this is specifically an expression of the favorable effect of habitual energy expenditure on secondary aging. (humankinetics.com)
  • Athletes who maintain high levels of sport activity through their adult years can expect to benefit from limited secondary aging. (humankinetics.com)
  • The National Institute on Aging (NIA) invites applications for short-term (up to two years) projects involving secondary analysis of CALERIE (Comprehensive Assessment of Long-term Effects of Restricting Intake of Energy) data set and / or stored biospecimens. (nih.gov)
  • normally
  • In laboratory studies, oral administration of Navitoclax to either sublethally irradiated or normally aged mice reduced senescent cells, including bone marrow hematopoietic stem cells and muscle stem cells. (wikipedia.org)
  • Both the sizes and weights of the testes normally decrease with age. (wikipedia.org)
  • species
  • In Maryland, an old growth forest is defined as a minimum of five acres in size with a preponderance of old trees, of which the oldest trees exceed at least half of the projected maximum attainable age for that species, and that exhibits most of the following characteristics: Shade tolerant species are present in all age/size classes. (wikipedia.org)
  • affects
  • The perception of a positive or negative emotion on a face affects the way that an individual perceives and processes that face. (wikipedia.org)
  • genetics
  • Age as a factor affecting behavior was not considered in animal studies of behavior genetics, and in general has not been seriously examined in animal behavioral research. (springer.com)
  • Factors such as genetics, diet and overall health can affect timing. (wikipedia.org)
  • preference
  • Specifically, while newborns show a preference for faces, this behavior is reduced between one- to four months of age. (wikipedia.org)
  • Around three months of age, a preference for faces re-emerges and interest in faces seems to peak late during the first year but then declines again slowly over the next two years of life. (wikipedia.org)
  • Interestingly, the re-emergence of a preference for faces at three months of age may be influenced by the child's own motor abilities and experiences. (wikipedia.org)
  • study
  • People who live under stress should try to get rid of their habit because a study done by Brigham and Women's Hospital in Boston found that stress can make people age faster than those who are stress-free. (onlymyhealth.com)
  • Post-excavation analysis constitutes processes that are used to study archaeological materials after an excavation is completed. (wikipedia.org)
  • known
  • Whether high levels of physical activity can extend the natural, or primary, aging process is not known, but at present, no evidence supports that idea. (humankinetics.com)
  • The first period usually begins between twelve and fifteen years of age, a point in time known as menarche. (wikipedia.org)
  • However, since real estate markets are known to be highly inefficient, and market transaction data is subject to significant error, the appraisal process generally relies on multiple simultaneous approaches to value, with a judgmental reconciliation as the final step to arrive at the appraiser's opinion. (wikipedia.org)
  • rats
  • Beginning at 4 months of age, 62 rats were housed in cages with running wheels. (humankinetics.com)
  • There have been exceptions, including the early age-related research studies of rats by Slonaker (1912), Richter (1922), and Stone (1929). (springer.com)
  • years
  • It is a randomized controlled trial in young and middle-aged healthy non-obese individuals, who are randomized to a program targeting 25% CR below their habitual ad libitum intake for two years or to maintaining their usual diet. (nih.gov)
  • Menstruation stops occurring after menopause which usually occurs between 45 and 55 years of age. (wikipedia.org)
  • The average age of menarche is approximately 12.5 years in the United States, 12.7 in Canada, 12.9 in the UK and 13.1 years in Iceland. (wikipedia.org)
  • The average age of menopause in women is 52 years, with anywhere between 45 and 55 being common. (wikipedia.org)
  • The variability of menstrual cycle lengths is highest for women under 25 years of age and is lowest, that is, most regular, for ages 25 to 39. (wikipedia.org)
  • Finally, the new leader's Age is important because he or she will need to have an appropriate career path after stepping down five years from now. (wikipedia.org)
  • This legacy we can see today as most of our older forests are the same age and are approximately 100 years old. (wikipedia.org)
  • time
  • Several selected test factors such as media height ofBAF£¬hydraulic retention time(HRT)£¬the air/water ratio and concentration of NH4+-N in raw water were studied in the article. (semanticscholar.org)
  • Muscle mass changes over time as a result of changes in testosterone and estrogen levels and exercise, besides other factors. (wikipedia.org)
  • Natural processes dictate the age composition at any time. (wikipedia.org)
  • experimental
  • Although the science of aging is generally clouded in mystery, one piece of experimental data has been repeatedly established: In animals, a low-calorie diet that is sufficient in specific nutrients (does not lead to malnutrition) will extend life span. (humankinetics.com)
  • This process is experimental and the keywords may be updated as the learning algorithm improves. (springer.com)
  • However
  • However, as we age, the antioxidant defense system becomes less efficient through down-regulation of oxidative enzymes. (nuskin.com)
  • However, factors such as age, preexisting conditions, and extent of injury will affect the recovery process. (wikipedia.org)
  • In practice, however, most appraisers use standard costing services for cost estimates and use an age-life method for depreciation. (wikipedia.org)
  • causes
  • That's because a process called glycation causes sugars to attach to proteins in collagen and elastin, which can make skin look older. (onlymyhealth.com)
  • The hormone drop causes the uterus to shed its lining in a process termed menstruation. (wikipedia.org)
  • The syndrome is more common in people over the age of 50 because osteoarthritis in the neck region causes weakening of the vertebrae. (wikipedia.org)
  • A slow, chronic cause in this age group is when the cord gets caught and squeezed between a posterior intervertebral disc herniation against the anterior cord and/or with posterior pressure on the cord from hypertrophy of the ligamentum flavum (Lhermitte's sign may be the experience that causes the patient to seek medical diagnosis). (wikipedia.org)
  • implications
  • Busse, Ewald W. Therapeutic Implications of Basic Research with the Aged: The Fourth Annual Institute of Pennsylvania Hospital Award Lecture in Memory of Edward A. Strecker, M.D. [Nutley, NJ: Roche Laboratories, (wikipedia.org)
  • body
  • The NT Factor® formula may help with the much-required nutrition to individual cells and mitochondrial membranes in the body. (pureformulas.com)
  • The aging process has an inevitable impact on a person's body shape. (wikipedia.org)
  • These factors result in women's waist-hip ratio (WHR) being lower than for males, although males tend to have a greater upper-body to waist-hip ratio (WHR) giving them a V shape look because of their greater muscle mass e.g. they generally have much larger, more muscular & broader shoulders, pectoral muscles, teres major muscles & latissimus dorsi muscles. (wikipedia.org)
  • environmental
  • A paintings conservator may also be called upon to consult with the RCM and an exhibition design team to ensure a work is stable enough for display, and determine how much exposure to environmental factors, such as humidity or light, it can withstand. (wikipedia.org)
  • A painting's natural aging process, as well as environmental factors, can require intervention by a paintings conservator to restore the work. (wikipedia.org)
  • treatments
  • Ultraviolet Light Ultraviolet light examinations are used to reveal varnishes and their ages, as well as previous treatments to a painting. (wikipedia.org)
  • similar
  • Infants as young as two days of age are capable of mimicking the facial expressions of an adult, displaying their capacity to note details like mouth and eye shape as well as to move their own muscles in a way that produces similar patterns in their faces. (wikipedia.org)
  • normal
  • The Duke Longitudinal Studies of Normal Aging, 1955-1980: Overview of History, Design, and Findings. (wikipedia.org)
  • papers
  • Aging, the Universal Human Experience: Selected Papers from the Symposia of the XIIIth Congress of the International Association of Gerontology. (wikipedia.org)
  • present
  • With advancing age, a larger percentage of our cells, even though they're present, are useless. (nuskin.com)
  • levels
  • They are produced in both men and women, but their levels are significantly higher in women, especially in those of reproductive age. (wikipedia.org)
  • months of age
  • Running distances gradually decreased, falling to 965 meters daily at 34 months of age. (humankinetics.com)
  • By at least seven months of age, infants are also able to use facial expressions to understand others' behavior. (wikipedia.org)
  • condition
  • This research ensures the continued existence of cultural heritage in the best condition possible considering their age and degradation. (wikipedia.org)
  • Components
  • Infants at this age show greater negative central components to angry faces that are looking directly at them than elsewhere, although the direction of fearful faces' gaze produces no difference. (wikipedia.org)