• These findings suggest that upregulated expression of p22phox mRNA and enhanced NADH oxidase activity contribute to the impaired endothelium-dependent vasodilation in OLETF rats. (diabetesjournals.org)
  • Vascular complications are responsible for the excess mortality associated with diabetes ( 1 ), and impaired endothelium-dependent vasodilation has been described in humans and in animal models of the disease ( 2 - 6 ). (diabetesjournals.org)
  • A single high-fat Western meal transiently reduces endothelium-dependent vasodilation at rest but the interaction with sympathetic vasoconstrictor activity during exercise remains unknown. (researchgate.net)
  • Atropine (250-550 mcg) inhibits vasodilation and decreases the secretory response of the pancreas to secreting Previous intra-arterial injection of bradykinin restores the secretory response of the pancreas, thus showing that inhibitory effect of, of the atropine on the secretory response of the pancreas to secretin is partly mediated by inhibition of secretin-induced vasodilation. (erowid.org)
  • Acetylcholine causes cardiac inhibition, vasodilation, gastrointestinal peristalsis and other parasympathetic effects. (nutrimedical.com)
  • 3,4 Control of this process relies on inhibition of key steps by complement component 1 esterase inhibitor (C1-INH), but in patients with HAE, adequate functional C1-INH is lacking. (ajmc.com)
  • Conversely, even prolonged intra-arterial infusion of secretin does not release pancreatic stores of histamine: In fact, endogenous synthesis and release of histamine seem to play no role in the regulation of functional vasodilation in the pancreas. (erowid.org)
  • Purpose ATP could play an important role in skeletal muscle blood flow regulation by inducing vasodilation via purinergic P2 receptors. (researchgate.net)
  • These thermal regulation mechanisms are examples of negative feedbacks, where the body attempts to maintain body temperature at an optimal level by adjusting physiological processes based on ambient temperature. (astronoo.com)
  • This mass-building, pump-producing dynamo is highly reactive and plays a critical role in increased blood flow by a process called vasodilation, for improved nutrient delivery, amplified growth signals, muscle recovery and increased endurance. (prosource.net)
  • Biossays of sera extracted from arterial and venous chest blond on guinea pig ileum seem to indicate that vasodilation in the pancreatic vascular bed These is acompanied by release of active bradykinin into the venous effluent. (erowid.org)
  • In addition, EDTA Chelation Therapy blocks the slow calcium currents in the arterial wall, resulting in arterial vasodilation. (detoxamin.com)
  • When temperature is reduced stepwise to form biologically active is processed instead of the cyclopropyl analgesic activity (he named percocet 8 mg in the selectivity: Measure of a selective filter. (themauimiracle.org)
  • After pancreatic stores of photohistamine have been released by compound 48/80, secretin-induced vasodilation still work occurs. (erowid.org)
  • Do to this increased travel to your body fat, micro-vasodilation occurs in your fingertips and sometimes toes to compensate. (leangains.com)
  • Heat syncope-sudden fainting caused by vasodilation-occurs in unacclimated people standing in the heat or after 15-20 minutes of exercise. (cdc.gov)
  • Endogenous substances and drugs that cause vasodilation are termed vasodilators. (wikipedia.org)
  • Localized tissues have multiple ways to increase blood flow, including releasing vasodilators, primarily adenosine, into the local interstitial fluid, which diffuses to capillary beds, provoking local vasodilation. (wikipedia.org)
  • The atherosclerotic process is accelerated by a myriad of factors, such as the release of inflammatory chemokines and cytokines, the generation of reactive oxygen species (ROS), growth factors, and the proliferation of vascular smooth muscle cells. (hindawi.com)
  • this binding leads to vasodilation and increase in vascular permeability, resulting in localized swelling known as angioedema. (ajmc.com)
  • Besides the importance of this process, oxidation of LDL is not the sole initiator of inflammation, as the imbalance between oxidants and antioxidants is also important for the process of atherogenesis. (hindawi.com)
  • Characteristics of a tooth with a chronic periapical lesion include a long infectious process, as well as an imbalance between the number and virulence of microorganisms present on root canal system with regard to the resistance of the host 1-2 . (bvsalud.org)
  • Putting it in simple terms, vasodilation is a process that relaxes the blood vessel walls to allow veins and arteries to attain a slightly larger diameter. (labmeeting.com)
  • Therapeutic heat levels increase localized circulation through vasodilation, in which heat relaxes muscles of the capillaries causing their dilation and increased flow of nutrient-rich, oxygenated blood to promote health and healing from within. (dayspaassociation.com)
  • It contains a special blend of arginine and silicate that is proven to provide effective vasodilation without presenting any health risks. (labmeeting.com)
  • The other problem with the arginine-based approach is that conversion of extracellular arginine into NO is not a very efficient process, especially in people over age 40. (holisticprimarycare.net)
  • In addition to these chemical and biochemical properties, NO can modulate cellular and physiological processes to limit oxidative injury, limiting processes such as leukocyte adhesion. (researchgate.net)
  • Atherosclerosis and endothelial dysfunction are diffuse disease processes affecting coronary and peripheral arteries, hence, the physiological basis in assessing endothelium-dependent vasomotion in peripheral vessels. (escardio.org)
  • Vasodilation works to decrease TPR and blood pressure through relaxation of smooth muscle cells in the tunica media layer of large arteries and smaller arterioles. (wikipedia.org)
  • Vasodilation is the result of relaxation in smooth muscle surrounding the blood vessels. (wikipedia.org)
  • Dephosphorylation by myosin light-chain phosphatase and induction of calcium symporters and antiporters that pump calcium ions out of the intracellular compartment both contribute to smooth muscle cell relaxation and therefore vasodilation. (wikipedia.org)
  • Regardless, the process of relaxation requires a decreased intracellular Ca2+ concentration and increased MLC phosphatase activity. (onteenstoday.com)
  • This color represents changing degrees of relaxation or stress based on the physiological process of vaso-dilation and vaso-constriction.Dry warm hands represent relaxation. (social-anxiety.com)
  • Therefore, with the aim to summarize the current knowledge on the initiation of the atherosclerotic process, in this paper, we review the early markers of atherosclerosis and we address the main therapeutic targets for preventing atheroma formation at its very initial stages focusing on inflammation, oxidative stress, endothelial dysfunction, and the interaction between platelets and endothelium. (hindawi.com)
  • How Does Vasodilation Rid the Muscles of Unwanted Chemicals? (labmeeting.com)
  • Such feelings are very hard to "work through", but whenever the blood supply is increased by vasodilation the cardiovascular system is able to flush the muscles of unwanted chemicals more efficiently. (labmeeting.com)
  • How Does Vasodilation Feed the Muscles? (labmeeting.com)
  • Oxygen is required for a process called cellular respiration that provides the muscles with ATP (a valuable energy source) and the harder the muscles are worked the more ATP they require. (labmeeting.com)
  • When you perform intense exercise, your muscles can't produce enough energy with oxygen alone, and use a parallel process to create energy that has lactic acid as a byproduct. (zensah.com)
  • heat expands the blood vessels in a process called vasodilation, allowing for increased blood flow to the muscles. (zensah.com)
  • The combined effects of smoking and hypercholesterolemia on the inflammatory process, the thrombosis/fibrinolysis system, and forearm hyperemic response were investigated. (nih.gov)
  • This phenomenon was associated with a respective increase in the inflammatory process and changes in the thrombosis/fibrinolysis system. (nih.gov)
  • New capillaries speed up the healing process by carrying more oxygen as well as more nutrients needed for healing and they can also carry more waste products away. (nutrimedical.com)
  • Stimulate fibroblastic activity which aids in the repair process. (nutrimedical.com)
  • Stimulate tissue granulation and connective tissue projections, which are part of the healing process of wounds, ulcers or inflamed tissue. (nutrimedical.com)
  • Simultaneously, proper heat levels stimulate the skin's natural process of self-hydration to the stratum corneum, increasing active topical ingredient penetration up to 10 times over dry skin. (dayspaassociation.com)
  • Edema, which is the swelling or natural splinting process of the body, has two basic components. (nutrimedical.com)
  • The chemical building blocks of proteins are essential to the human body and all its processes. (prosource.net)
  • Fasting increases the blood flow to you body fat (the process is called adipose tissue blood flow). (leangains.com)
  • Metabolic reactions are the chemical processes that occur in the cells of our body to sustain life by performing functions such as energy production, molecule synthesis, cell repair and repair. (astronoo.com)
  • Cirrhosis is defined histologically as a diffuse hepatic process characterized by fibrosis and conversion of the normal liver architecture into structurally abnormal nodules. (medscape.com)
  • therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. (nih.gov)
  • Paracentesis is essential in determining whether ascites is caused by portal hypertension or by another process. (medscape.com)
  • cell renewal (essential process to maintain the integrity of tissues and organs). (astronoo.com)
  • Inflammation and immunity are key factors for the development and complications of atherosclerosis, and therefore, the whole atherosclerotic process is a target for diagnosis and treatment. (hindawi.com)
  • The response may be intrinsic (due to local processes in the surrounding tissue) or extrinsic (due to hormones or the nervous system). (wikipedia.org)
  • It seems that ALA has a special ability to reduce bone resorption-the process of bone-dismantling cells breaking down bone tissue. (barleans.com)
  • Destruction of the infection and clean up must occur before the healing process can take place. (nutrimedical.com)
  • this process diverts the flow of heated blood to the skin of the animal, where heat can be more easily released to the environment. (wikipedia.org)
  • For example, when a marine mammal moves into warm seas, as many whales do when they reproduce, excess metabolic heat is removed by vasodilation of numerous blood vessels in the outer layer of the skin. (tvacres.com)
  • ALA can protect neurons, support vasodilation (the widening of blood vessels), and encourage neuroplasticity (the ability of the brain's neural networks to grow and reorganize 6 ). (barleans.com)
  • Although these techniques tackle the coupling between neuronal activity and metabolism, they lack chemical specificity and fail in providing information on neuronal and glial metabolic pathways underlying those processes. (frontiersin.org)