• occur
  • citation needed] To understand the DNA damage theory of aging it is important to distinguish between DNA damage and mutation, the two major types of errors that occur in DNA. (wikipedia.org)
  • Symptoms, if they occur, generally do not begin until middle age. (wikipedia.org)
  • these persistent, or epigenetic, changes are of particular interest because they are key to normal and abnormal growth: they occur during organismal development into multicellular tissues and organs, and are typically disrupted during abnormal reversal of tissue specialization and growth control as in cancer, as well as during aging of cells and individuals. (upenn.edu)
  • People whose difficulties occur only occasionally tend to believe the problem doesn't warrant seeking advice from a physician. (thefreelibrary.com)
  • These infections are most likely to result in epilepsy when they occur at an early age. (wikipedia.org)
  • commonly
  • The above problems are more commonly associated with old age but due to many factors such as poor component design, proximity of the user to the screen and an excess of consecutive working hours mean that the above problems can feature in both young and old computer users. (wikipedia.org)
  • Population
  • As an example, they described a study showing that centenarians of 100 to 107 years of age had higher levels of two DNA repair enzymes, PARP1 and Ku70, than general-population old individuals of 69 to 75 years of age. (wikipedia.org)
  • According to the report, our total average nightly sleep time has declined 20 percent in this century because of our 24-hour society, the globalization of the economy, and factors such as the stress of recession and unemployment, longer work hours, and the aging of the population. (thefreelibrary.com)
  • Demographers tend to define infertility as childlessness in a population of women of reproductive age," whereas "the epidemiological definition refers to "trying for" or "time to" a pregnancy, generally in a population of women exposed to" a probability of conception. (wikipedia.org)
  • cause
  • Overall, they concluded that while the complexity of responses to DNA damage remains only partly understood, the idea that DNA damage accumulation with age is the primary cause of aging remains an intuitive and powerful one. (wikipedia.org)
  • How to maintain a good sex life in old age and what factors cause problems with sex life among the elderly? (medindia.net)
  • Suicide is the 10th-leading cause of death among Americans, according to the Centers for Disease Control and Prevention, and in 2016, the national age-adjusted suicide rate reached the highest level in decades. (hollandsentinel.com)
  • It's the fourth-leading cause of death among men ages 35-54. (hollandsentinel.com)
  • The most common cause of female infertility is ovulatory problems which generally manifest themselves by sparse or absent menstrual periods. (wikipedia.org)
  • Updated NICE guidelines do not include a specific definition, but recommend that "A woman of reproductive age who has not conceived after 1 year of unprotected vaginal sexual intercourse, in the absence of any known cause of infertility, should be offered further clinical assessment and investigation along with her partner, with earlier referral to a specialist if the woman is over 36 years of age. (wikipedia.org)
  • These variations are not usually enough to cause a problem, but occasionally they do. (wikipedia.org)
  • While these factors do not cause paraphrenia, they do make individuals more likely to develop the disorder later in life. (wikipedia.org)
  • The main cause of CTS seems to be debatable, however, with many sources saying that the syndrome is predominantly caused by the acute positioning of the wrist while typing and this problem is exacerbated by the need for the user to be crouching towards the screen while typing. (wikipedia.org)
  • diagnosis
  • The information should not be used for either diagnosis or treatment or both for any health related problem or disease. (medindia.net)
  • While the diagnosis of paraphrenia is not currently included in the DSM-IV or the ICD-10, many studies have recognized the condition as "a viable diagnostic entity that is distinct from schizophrenia, with organic factors playing a role in a significant portion of patients. (wikipedia.org)
  • notable
  • Series 5 has been the most successful UK X Factor years, with Alexandra Burke, JLS, Diana Vickers, Ruth Lorenzo and Laura White all having careers after the show and becoming some of the most notable X Factor contestants of all time. (wikipedia.org)
  • frequent
  • TOT becomes more frequent as people age. (wikipedia.org)
  • Increasing evidence is being shown for the elevation of associated problems by the frequency and age at which cannabis is used, with young and frequent users being at most risk. (wikipedia.org)
  • In many cases, frequent computer users suffer from computer vision syndrome, which is a degenerative eye problem which can result in severely reduced eyesight (Myopia), blurred vision, overall eye tiredness and even Glaucoma. (wikipedia.org)
  • daytime
  • According to one of the Gallup surveys, individuals who experience occasional insomnia reported a laundry list of daytime functioning problems and compromised well-being compared to normal sleepers. (thefreelibrary.com)
  • alcohol
  • Many forego any medical attention for their problem, while four in 10 self-medicate, without benefit of physician advice, by using over-the-counter remedies, alcohol, or both. (thefreelibrary.com)
  • Research that has been done on this age group had previously explored more negative aspects, such as problem and risk behaviours (i.e. drug and alcohol use). (wikipedia.org)
  • Chronic
  • Forty million Americans suffer chronic sleep disorders and an additional 20 to 30 million experience intermittent problems due to lifestyle factors, according to a Report of the National Commission on Sleep Disorders Research entitled "Wake Up America: A National Sleep Alert,"(1), which was submitted to Congress in January. (thefreelibrary.com)
  • occurs
  • Epilepsy most often occurs at the extremes of life - in childhood or in very old age - but can develop at any time throughout one's life. (wikipedia.org)
  • decrease
  • The number of eggs in the woman and the sperm in the men tends to decrease after age 30. (hubpages.com)
  • Less light reaches the back of the eyes because the pupils decrease in size as you age, the lens inside your eye becomes thicker, and the lens scatters more light, causing objects and colors to appear less vivid. (wikipedia.org)
  • motivation
  • One factor of obvious relevance is motivation, and studies have been conducted regarding motivation to learning second language, and the relationship of fossilization to the learner's communicative needs. (wikipedia.org)
  • Once a "willful" violation has been shown, the employee need not additionally demonstrate that the employer's conduct was outrageous, provide direct evidence of the employer's motivation, or prove that age was the predominant rather than a determinative factor in the employment decision. (cornell.edu)
  • difficulty
  • Problems included significantly impaired ability to concentrate during the day and accomplish needed tasks, memory problems, difficulty coping with minor irritations, less ability to enjoy family and social relationships, and feeling generally unwell physically. (thefreelibrary.com)
  • time
  • Given these properties of DNA damage and mutation, it can be seen that DNA damages are a special problem in non-dividing or slowly dividing cells, where unrepaired damages will tend to accumulate over time. (wikipedia.org)
  • On close evaluation, it was observed that women who expressed problems of forgetfulness had a tough time grasping new information, actually impersonating a memory problem. (medindia.net)
  • so are sleep problems for a short period of time, due to the stress of temporary changes in situation such as a new job or family illness. (thefreelibrary.com)
  • This is an extremely important issue as computers become more important in every corner of employment the medical effects caused by them will elevate unless sufficient research is performed and time is dedicated into eliminating and reducing these problems as much as possible. (wikipedia.org)
  • distinct
  • Thus, it would be incorrect to say that a decision based on years of service which is analytically distinct from age is necessarily age-based. (cornell.edu)
  • memory problems
  • A study of 800 women in 2003 showed no links between menopause and memory problems, though neurophysiologists face a consistent flow of such patients. (medindia.net)
  • What Weber and Mapstone did further was to subject 24 women with complaints of memory problems through a series of tests that aimed at studying their cognitive skills along with their traditional memory. (medindia.net)
  • experience
  • As people age, they experience neurodegeneration in the retina and in the suprachiasmatic nucleus (SCN). (wikipedia.org)
  • fertile
  • That means that the most fertile and high quality eggs are produced in the age group of 20 to 30. (hubpages.com)
  • high
  • Additionally, the Board's interdisciplinary positioning and high standing in academic circles allows committees to assemble diverse experts, both within their memberships and at workshops and events, in order to synthesize research in novel ways to address critical problems. (nationalacademies.org)
  • women
  • According to the study team, from the University of Rochester Medical Center, the problem was not so much flawed memory, as much as grievance of forgetfulness and the manner in which these women grasp new information. (medindia.net)
  • Miriam Weber and Mark Mapstone, both memory experts at the University's Memory Disorders Clinic, have come in contact with increasing number of middle-aged women having such problems with forgetfulness. (medindia.net)
  • Some studies find that women have a slightly higher death rate as much as 18 years after bypass surgery, but any difference seen was small and probably due to their older age. (simstat.com)
  • However, when younger women develop heart disease, they are 2 to 3 times more likely to die than men of the same age. (simstat.com)
  • main
  • Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. (wikipedia.org)
  • naturally
  • Hypothesis that aging is caused by accumulated DNA danage The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. (wikipedia.org)
  • contribute
  • Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction). (wikipedia.org)
  • important
  • Selinker suggests that the most important distinguishing factor related to second language acquisition is the phenomenon of fossilization. (wikipedia.org)
  • The figure for people working with and using computers recreationally is to increase considerably in the coming years so it is crucially important that these problems are identified and resolved sooner rather than later in an effort to reduce if not eradicate these problems. (wikipedia.org)
  • given
  • Descriptions of reduced function, characteristic of aging and associated with accumulation of DNA damage, are given later in this article. (wikipedia.org)
  • Does the education given by the nation's human factors graduate training programs meet the skill and knowledge needs of today's employers? (nationalacademies.org)
  • Like the other members of Team X, he was given an artificial age suppressant so he was likely much older than he looked. (wikipedia.org)
  • Years later, John had tracked Wolverine and the rest of his old teammates down because it seemed that there was a problem with the age suppression factors given to them by Weapon X, as one of their number, Mastodon, had suddenly aged quite rapidly and been reduced into a pile of ooze. (wikipedia.org)