• real probenecid
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  • renal
  • As noted, probenecid may not be effective in chronic renal insufficiency particularly when the glomerular filtration rate is 30 mL/minute or less. (rxlist.com)
  • Interestingly, and somewhat paradoxically, this means that probenecid reduces nephrotoxicity while also DECREASING the renal clearance of the drug and thus INCREASING serum cidofovir concentrations as much as two-fold. (blogspot.com)
  • drugs
  • Probenecid is a banned drug for athletes for a related reason - because it blocks entry of certain drugs into the urine, it has been used as a masking agent for other banned performance-enhancing drugs including steroids. (blogspot.com)
  • By their mechanism of action, some uricosurics (such as probenecid) increase the blood plasma concentration of certain other drugs and their metabolic products. (wikipedia.org)
  • uptake
  • Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexi" by Archana Bhaskaracharya, Phuong Dao-Ung et al. (edu.au)
  • However, we found that probenecid inhibited P2X7-induced cationic and anionic dye uptake in stably transfected human P2X7 HEK-293 cells. (edu.au)
  • attacks
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  • generic
  • Probenecid is the generic name for 4-[(dipropylamino)sulfonyl] benzoic acid. (egeneralmedical.com)
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  • price
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  • The lowest GoodRx price for the most common version of probenecid is around $23.51, 60% off the average retail price of $59.42. (goodrx.com)
  • Human
  • Patch clamp and calcium indicator experiments revealed that probenecid directly blocks the human P2X7 receptor. (edu.au)
  • Mycophenolic acid acyl-glucuronide (AcMPAG) is an important product in the metabolism of mycophenolic acid, and ABHD10 is the major esterase responsible for the AcMPAG and probenecid acyl glucuronide deglucuronidation in human liver. (wikipedia.org)
  • List
  • Probenecid was in the IOC list, but not in the UCI list (it would be one month later) and rule number 35 of the 1988 Tour regulations stated that the doping test would be carried out in accordance with the UCI rules. (wikipedia.org)
  • administration
  • Nephrotoxicity can be reduced by co-administration with iv fluids and probenecid (the dosing regimen for the latter is 2g po 3 hours prior to the dose, then 1 g po 2 hours and 8 hours after. (blogspot.com)