• A cocktail of five recombinant proteins optimized for conserved GI nematode targets was used immunize pigs and test for active antibody responses in both the serum and intestinal ileal fluid of immunized pigs. (frontiersin.org)
  • Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. (gentaur.com)
  • Igor Stagljar, the study's senior author, told ProteoMonitor this week that his team has been interested broadly in how integral membrane proteins interact at the genome-wide level. (genomeweb.com)
  • Bicelles have been used so far primarily as hosts for membrane proteins. (springer.com)
  • Stagljar and his colleagues previously developed a method, called a membrane yeast two-hybrid, or MYTH assay to allow them to study interactions of full-length membrane proteins in their natural cellular environment. (genomeweb.com)
  • The N protein is the most highly expressed of the four major coronavirus structural proteins. (wikipedia.org)
  • The N protein is the most highly expressed in host cells of the four major structural proteins. (wikipedia.org)
  • Like the other structural proteins, the gene encoding the N protein is located toward the 3' end of the genome. (wikipedia.org)
  • The effect of pregnancy on transport proteins is unknown. (nih.gov)
  • The latter, Stagljar said, is an important area for drug development, because it opens the possibility that you could block ABC transporter activity by blocking associated zinc transport proteins. (genomeweb.com)
  • The N protein is highly immunogenic and antibodies to N are found in patients recovered from SARS and COVID-19. (wikipedia.org)
  • Antibodies attach tags for destruction to specific proteins, marking them as unwanted. (eurekalert.org)
  • Tang's group focused on antibodies, which are ideal candidates since they recognize and bind to specific proteins. (eurekalert.org)
  • Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. (gentaur.com)
  • The antibodies bind with high affinity in the central region of the surface-bound M protein. (lu.se)
  • Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. (bvsalud.org)
  • Using the information encoded in the genes, ribosomes produce proteins that control many chemical processes in living organisms. (wikipedia.org)
  • Regulation of gene expression is primarily controlled by changes in the proteins that occupy genes' regulatory elements. (nature.com)
  • SIRT1 is localized in the nucleus and can deacetylate numerous proteins such as tumor suppressor protein (p53), Ku70, NF-κB, and forkhead proteins which modulate genes that control cellular stress resistance ( Smith, 2002 ). (frontiersin.org)
  • N-linked glycosylation is the most prevalent posttranslational modification of plasma membrane and secretory proteins and participates in many important biological roles such as protein folding, intracellular targeting, immune response, cell adhesion, and protease resistance. (jneurosci.org)
  • Here, we used a genomics/proteomics approach (including immunoblot experiments from pigs infected with T. suis ) to prioritize putative immunogenic excretory/secretory (E/S) proteins conserved across and specific to several gastrointestinal (GI) parasitic nematode species. (frontiersin.org)
  • Though the group did the mapping with ABC transporters from a yeast species - Saccharomyces cerevisiae - many of the proteins are homologous to disease-linked human ABC proteins. (genomeweb.com)
  • An antibody-protein array of putative immunogenic proteins was developed from a combined bioinformatic, experimental, and literature-based prioritization of homologous parasite proteins. (frontiersin.org)
  • Screening the array with sera and ileal fluid samples from immunized pigs suggested cross-reactivity among homologous proteins and a general activation of immunity. (frontiersin.org)
  • This saliva contains over one hundred unique proteins which can modulate many physiological functions, facilitating blood feeding. (sbir.gov)
  • The way you cook protein and carbohydrates changes their textures and flavors, as well as their nutrient profile. (livestrong.com)
  • When it comes to the basics of a healthy diet, protein and carbohydrates are probably the top macronutrients on your mind. (livestrong.com)
  • As a result, Northern Arizona University Athletics recommends consuming a small meal consisting of low-glycemic carbohydrates and a quality protein before your workouts. (livestrong.com)
  • Dr. Kati Mora of Fitness Magazine recommends apple wedges, which provide the low-glycemic carbohydrates, with almond butter, which offers up protein. (livestrong.com)
  • They are primarily broken into carbohydrates, proteins, and fats. (scifidimensions.com)
  • The Mediterranean diet typically consists of "50% carbohydrates-including grains and veggies, about 15% proteins, and 35% fats," says registered dietitian Isabel Smith, R.D., CDN . (scifidimensions.com)
  • A standard Mediterranean diet is made up primarily of carbohydrates from vegetables and whole grains, along with protein and trace amounts of healthy fats. (scifidimensions.com)
  • Proteins that share the common characteristic of binding to carbohydrates. (bvsalud.org)
  • Many researchers over the past several years, including the Tang group, have developed tools to selectively target for destruction certain cellular proteins found on the inside of cells, named PROTACs. (eurekalert.org)
  • We developed genomic locus proteomics (GLoPro), in which we combine CRISPR-based genome targeting, proximity labeling, and quantitative proteomics to discover proteins associated with a specific genomic locus in native cellular contexts. (nature.com)
  • The cellular increase was due primarily to macrophage influx. (cdc.gov)
  • One half of a split ubiquitin molecule is attached to an ABC transporter (or another cellular protein of interest) and the other half to its potential interaction targets. (genomeweb.com)
  • What type of protein, sugars and fat does it contain? (acefitness.org)
  • It recognizes certain sugars on proteins and delivers the proteins to the lysosome for digestion. (eurekalert.org)
  • To help encourage ASGPR to recognize and help destroy disease-causing proteins, researchers in earlier studies learned they could attach three specific sugars to the proteins. (eurekalert.org)
  • However, many bars on the market aren't the healthiest option as they're made with heavily processed ingredients, low in essential nutrients like protein and fiber, and high in added sugars. (loseit.com)
  • The GFB: Gluten Free Bar Peanut Butter flavor provides 240 calories, 10g fat (1.5g saturated), 28g carb, 2g fiber, 12g total sugars (6g added sugars), and 12g protein. (loseit.com)
  • The individual protein subunit of the virus capsid and formed in repetitive sequence. (innvista.com)
  • The 3 × 10 −4 G 0 level is attributed to a single SARS-CoV-2 protein connecting to the two STM Au nano-electrodes from the receptor binding domain (RBD) subunit and the S1/S2 cleavage site. (rsc.org)
  • A lower 4 × 10 −6 G 0 conductance is attributed to the spike protein connecting to the STM electrodes from the RBD subunit and the N-terminal domain (NTD). (rsc.org)
  • For example, the spike proteins (S1 and S2) of SARS-CoV-2 contain 14 S-S bonds in well-defined regions, with 10 S-S bridges in the S1 subunit. (rsc.org)
  • by binding to the 50S subunit of the ribosome, they inhibit bacterial protein synthesis. (msdmanuals.com)
  • The DMD gene provides instructions for making a protein called dystrophin . (medlineplus.gov)
  • Patient selection for patients with locally advanced or metastatic gastric cancer is based on HER2 protein overexpression or HER2 gene amplification. (unboundmedicine.com)
  • The N-terminal A domain differs among the four subtypes of Ca 2+ channel β subunits (β 1 -β 4 ) primarily as the result of two duplications of an ancestral gene containing multiple alternatively spliced exons. (jneurosci.org)
  • They found that after the protein was manufactured in the nucleus, it traveled outward through the cell's many branching dendrites and eventually settled in far-flung synapses. (technologyreview.com)
  • Recombinant expression of proteins of interest in Escherichia coli is an important tool in the determination of protein structure. (iucr.org)
  • An impediment to the successful production of large quantities of natively folded proteins in Escherichia coli is the tendency of many proteins to become insoluble when overexpressed. (iucr.org)
  • One Chocolate Peanut Butter Larabar Protein Bar provides 230 calories, 10g fat (2.5g saturated), 24g carb, 4g fiber, 18g total sugar (2g added sugar), and 11g protein. (loseit.com)
  • One Aloha Chocolate Chip Cookie Dough Protein Bar provides 220 calories, 10g fat (3g saturated), 25g carb, 14g fiber, 4g total sugar, and 14g protein. (loseit.com)
  • One Chocolate Chip Cookie Dough Perfect Keto Bar provides 230 calories, 18g fat (6g saturated), 12g carb (3g net carbs), 9g fiber, 1g sugar, and 11g protein. (loseit.com)
  • The average diet today has 30% of our calories coming from protein. (naturalnews.com)
  • 1. Combat gout by insuring protein consumption does not exceed 10 -15% of calories consumed per day. (naturalnews.com)
  • In addition to its interactions with RNA, N forms protein-protein interactions with the coronavirus membrane protein (M) during the process of viral assembly. (wikipedia.org)
  • Formation of RNPs is thought to involve allosteric interactions between RNA and multiple RNA-binding regions of the protein. (wikipedia.org)
  • N is physically colocalized with the viral RNA-dependent RNA polymerase early in the replication cycle and forms interactions with non-structural protein 3, a component of the replicase-transcriptase complex. (wikipedia.org)
  • Researchers from the University of Toronto have created a map of the protein interactions of 19 members of the ATP-binding cassette transporter class in a species of yeast, combining this data with previously-reported ABC transporter interactions into a comprehensive "interactome. (genomeweb.com)
  • Overall, membrane protein interactions are difficult to study because of their biochemical features," he said. (genomeweb.com)
  • Briefly, MYTH adapts a previously developed split ubiquitin method as an in vivo sensor of protein-protein interactions. (genomeweb.com)
  • Overall, the study yielded a map covering 537 unique binary interactions across 366 proteins, the study authors wrote, which they annotated with functional classifications to create a standard map, as well as a map showing protein conservation in humans and known disease associations. (genomeweb.com)
  • The largest group - about 26 percent of the interactions - corresponds to proteins involved in transport and related processes. (genomeweb.com)
  • The second largest, with 16 percent, marks interactions with proteins of unknown function. (genomeweb.com)
  • The team attached the sugary tag that would activate ASGPR to an antibody that would track down the specific proteins they hoped to destroy. (eurekalert.org)
  • By attaching the sugary tag to an EGFR antibody, the scientists were able to deplete a significant amount of the protein that otherwise accumulated outside of cancerous liver cells grown in the lab. (eurekalert.org)
  • Remarkably, this antibody primarily interacts through a bivalent dual-Fab cis mode, where the Fabs bind to two distinct epitopes in the M protein. (lu.se)
  • The Tang lab is now expanding the scope of targets to additional proteins found outside of or on the surface of the liver cell. (eurekalert.org)
  • The receptor's "preference" for mushroom-type synapses suggests that, at least in the process of forming a fear-related memory, there is a specialized trafficking system to direct synaptic proteins to their targets. (technologyreview.com)
  • Testing indicates that the system is a valuable tool for these protein targets. (iucr.org)
  • 2. In the 1980s, many countries in the African Region made steady progress in reducing levels of protein energy malnutrition. (who.int)
  • 4. The major nutritional problems besetting the African Region are protein energy malnutrition and micronutrient deficiencies4. (who.int)
  • Malnutrition occurs in several linked forms, including intrauterine growth retardation, protein- energy malnutrition and deficiencies of micronutrients such as iodine, vitamin A, zinc and iron. (who.int)
  • The worldwide prevalence of protein-energy malnutrition, which contributes to 60% of the 10.9 million deaths each year among children under five in developing countries (see figure in Annex), is slowly decreasing. (who.int)
  • Protein source is whey isolate, which contains 90%+ of pure protein and amino acids, and has been shown to allow for higher rates of digestion and absorption. (acefitness.org)
  • Protein sources are a blend of whey protein isolate and milk protein isolate. (acefitness.org)
  • Protein content is a blend of whey protein concentrate, whey protein isolate and milk protein isolate. (acefitness.org)
  • This report analyzes the worldwide markets for Whey Protein Ingredients in Thousand Pounds (lbs). (prnewswire.com)
  • The report analyzes the market for Whey Protein Ingredients as a single consolidated segment. (prnewswire.com)
  • An example of a quality preworkout meal is a bowl of rolled oats with a scoop of whey protein and some peanut butter, milk and sliced banana. (livestrong.com)
  • 2. In addition to quality proteins the body needs adequate nutrients, primarily Vitamins B3 and B6 along with Zinc, to properly breakdown and utilize the protein that has been ingested. (naturalnews.com)
  • 1 nucleus with a static residual quadrupole coupling, also for the water-1H magnetization, even in systems with high enhanced I-spin relaxation is observed at I-spin Larmor frequencies water content, as long as the protein component is immobilized matching an eigenfrequency of the static S-spin Hamiltonian. (lu.se)
  • Emmon also recommends stir-frying and sauteeing your protein and veggies. (livestrong.com)
  • In a 2011 longitudinal study , researchers gave 17 men and women with type 2 diabetes moderately high protein snacks in the morning and afternoon (7 to 12 grams of protein) for four weeks, and compared the results with their normal eating habits for four weeks. (acefitness.org)
  • I also like how high in fiber it is (14 grams), which, combined with the 14 grams of protein, makes these bars super filling. (loseit.com)
  • Cyclin-dependent kinase 2-associating protein 1 commits murine embryonic stem cell differentiation through retinoblastoma protein regulation. (nih.gov)
  • Most of these clotting factors are vitamin K dependent proteins, which suggest that reduced vitamin K is essential for activating clotting factors. (hindawi.com)
  • Tak W. Mak, Ph.D., from the Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital in Toronto, and colleagues found that hypoxia stimulates an HIF1-dependent increase in a protein called FOXO3a. (genengnews.com)
  • Orthologous to human CDK2AP1 (cyclin dependent kinase 2 associated protein 1). (nih.gov)
  • The subjects who ate the two high-protein snacks lost a modest, but significant amount of weight (1 kg) during the four-week period. (acefitness.org)
  • Incorporating high-protein snacks , like hummus made of chickpeas, is an effective way to stay satiated between meals. (scifidimensions.com)
  • They currently offer just a handful of flavors, primarily chocolate-based. (loseit.com)
  • Scientists at the University of Wisconsin-Madison have developed a way to use a cell's own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs. (eurekalert.org)
  • Increased plasma volume and protein binding changes can alter the apparent volume of distribution (Vd) of drugs. (nih.gov)
  • Triamcinolone acetonide is primarily effective because of its anti-inflammatory, antipruritic and vasoconstrictive actions, characteristic of the topical corticosteroid class of drugs. (nih.gov)
  • With stir-frying and sauteing, you can get a great flavor out of vegetables and proteins by using high heat and low fat. (livestrong.com)
  • A typical plate would contain half vegetables, one-quarter whole grains, and one-quarter protein, according to Smith. (scifidimensions.com)
  • The proteins should be of high quality derived primarily from vegetables, beans, nuts, and legumes. (naturalnews.com)
  • Protein aggregation remains a significant problem in E. coli expression systems. (iucr.org)
  • Carbohydrate sources are from sugar alcohols and fiber primarily with additional carbs from cocoa powder and fats/oils. (acefitness.org)
  • Cooked Protein and Carbs: How Does Heat Change These Macros? (livestrong.com)
  • SIRT2 and FOXO3a protein levels increased only in the occipital lobe. (frontiersin.org)
  • In SARS-CoV, the causative agent of SARS, the N protein is 422 amino acid residues long and in SARS-CoV-2, the causative agent of COVID-19, it is 419 residues long. (wikipedia.org)
  • Muscle protein metabolism was measured in the basal state and during amino acid administration via L-[ring- 2 H 5 ]phenylalanine infusion, femoral arterial and venous catheterization, and muscle biopsies. (utmb.edu)
  • To get a complete amino acid profile in your diet, you'll want to vary your protein sources. (livestrong.com)
  • Protein is made up of amino acids - some of which your body makes on its own - but there is another group called essential amino acids , which you get from food. (livestrong.com)
  • Some foods contian all nine essential amino acids and are known as complete proteins. (livestrong.com)
  • N also serves as a chaperone protein for the formation of RNA structure in the genomic RNA. (wikipedia.org)
  • Synthesis of genomic RNA appears to involve participation by the N protein. (wikipedia.org)
  • Because lidocaine is also protein bound, low protein states may also increase risk. (medscape.com)
  • In the past, to develop a new drug, we often needed to find a molecule that bound to the protein of interest and also changed the function of the protein. (eurekalert.org)
  • Corticosteroids are bound to plasma proteins in varying degrees. (nih.gov)
  • Finally, the Gβγ dimeric protein interacts with GIRK channels to open them so that they become permeable to potassium ions, resulting in hyperpolarization of the cell membrane. (wikipedia.org)
  • From chicken and fish to dairy, eggs, beans and grass-fed meat, there are many delicious ways to get enough protein in your diet. (livestrong.com)
  • Expression of cell-cycle regulator CDK2-associating protein 1 (p12CDK2AP1) in transgenic mice induces testicular and ovarian atrophy in vivo. (nih.gov)
  • In high concentration PIP2 activates the channel absent G-protein, but G-protein does not activate the channel absent PIP2. (wikipedia.org)
  • The nucleocapsid (N) protein is a protein that packages the positive-sense RNA genome of coronaviruses to form ribonucleoprotein structures enclosed within the viral capsid. (wikipedia.org)
  • The N protein binds to RNA to form ribonucleoprotein (RNP) structures for packaging the genome into the viral capsid. (wikipedia.org)
  • Several mutations in the N terminus of the G-protein-coupled receptor rhodopsin disrupt NXS/T consensus sequences for N-linked glycosylation (located at N2 and N15) and cause sector retinitis pigmentosa in which the inferior retina preferentially degenerates. (jneurosci.org)
  • Mutations affecting glycosylation of the heptahelical G-protein-coupled receptor rhodopsin are associated with retinitis pigmentosa (RP), a disease characterized by progressive degeneration of photoreceptors. (jneurosci.org)
  • Follow the glow: By engineering mice to manufacture a fluorescently tagged glutamate receptor protein (shown in green) in active neurons, researchers could follow the protein's path as the mice learned to fear an electric shock. (technologyreview.com)
  • The studied protein is a receptor for glutamate, a neurotransmitter previously implicated in memory formation. (technologyreview.com)
  • The tagged glutamate receptor migrated primarily into the mushroom-type synapses. (technologyreview.com)
  • 8 The SARS-CoV-2 spike protein S1 is composed of three domains, the receptor binding domain (RBD) that contains 4 S-S bridges, the N-terminal domain (NTD) that contains 3 S-S bridges and the S1/S2 cleavage site that contains 3 S-S bridges ( Fig. 1a(iii) ). (rsc.org)
  • Cdk2ap1 expression is primarily regulated by progesterone and the progesterone receptor in uterus and is mainly localized to proliferating tissues. (nih.gov)
  • Phosphine is a respiratory tract irritant that attacks primarily the cardiovascular and respiratory systems causing peripheral vascular collapse, cardiac arrest and failure, and pulmonary edema. (cdc.gov)
  • SARS-CoV-2 spike proteins have peripheral disulfide bonds (S-S), which are common in all spike proteins of SARS-CoV-2 variants, in other types of coronaviruses ( e.g. (rsc.org)
  • In several coronaviruses, ADP-ribosylation of the N protein has also been reported. (wikipedia.org)
  • With unclear functional significance, the SARS-CoV N protein has been observed to be SUMOylated and the N proteins of several coronaviruses including SARS-CoV-2 have been observed to be proteolytically cleaved. (wikipedia.org)
  • In many coronaviruses, a population of N protein is localized to the nucleolus, thought to be associated with its effects on the cell cycle. (wikipedia.org)
  • Individuals acquire infection with coronaviruses primarily through direct contact with virus-positive individuals via aerosols. (rsc.org)
  • The structures of the spike proteins (S1 and S2) of most of the coronaviruses, including SARS-CoV-2 ( Fig. 1a(i) ), revealed that these proteins possess multiple disulfide (S-S) bonds. (rsc.org)
  • Although there are more than 36 types of amyloid precursor proteins, only nine build up in the myocardium and cause cardiac amyloidosis. (medscape.com)
  • As a Class I bacterial dioxygenases, benzoate dioxygenase like proteins combine an [2Fe-2S] cluster containing N-terminal ferredoxin at the end fused to an FAD/NADP(P) domain. (nih.gov)
  • Unlike other protein bars with long ingredient lists, Larabar Protein bars are made with just 6 recognizable ingredients: dates, peanuts, pea protein, semisweet chocolate chips, peanut oil, and salt. (loseit.com)
  • It has been shown that many salivary proteins enhance infectivity and pathogenesis of arboviruses by modulating immune responses at the bite site. (sbir.gov)
  • For those following a plant-based version of the diet, tofu, legumes, and nuts are also good sources of protein . (scifidimensions.com)
  • P. gingivalis HSP60 at a concentration of 10 ng/l significantly decreased the expression levels of VE‑cadherin and eNOS protein at 24 h stimulation, whereas no difference in these proteins was identified following a low dose of P. gingivalis HSP60 (1 ng/l). (spandidos-publications.com)
  • Since the liver is the primary organ that breaks down proteins in the body, it is an ideal tissue to selectively degrade undesired proteins. (eurekalert.org)
  • Inflammatory and tissue remodeling proteins in LLF followed a similar pattern. (cdc.gov)
  • 0.01) in muscle protein synthesis and no change in breakdown. (utmb.edu)
  • GPCRs in turn release activated G-protein βγ- subunits (Gβγ) from inactive heterotrimeric G protein complexes (Gαβγ). (wikipedia.org)
  • It won't work if you want to co-immunoprecipitate them or apply any proteomic biochemical method because you will have to use detergents, and then you destroy all the protein complexes. (genomeweb.com)
  • PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). (bvsalud.org)
  • Tang's lab is now working to refine the ASGPR method by making it more effective, and to expand the strategy to destroy proteins on the surface of other types of cells. (eurekalert.org)
  • And the third group - 15 percent- is involved primarily in metabolic processes, the study authors wrote. (genomeweb.com)
  • Fat content is primarily from nuts, nut oils, palm kernel oil and almond butter. (acefitness.org)
  • Ingredient-wise, these bars contain more highly-processed ingredients than Larabar Protein Bars. (loseit.com)
  • The features of bicelles open up intriguing new perspectives for templating, such as magnetic field-directed templating and immobilization of proteins in periodic mesostructures. (springer.com)
  • This strengthening is likely the result of a specific set of proteins migrating to synapses in a precisely choreographed pattern, but it remains a mystery which proteins are involved and how they are targeted to their destinations. (technologyreview.com)
  • These data indicate that this eukaryotic cell-free expression system has a high success rate and that the addition of specific reagents can increase the yield of soluble protein. (iucr.org)
  • Whether you refer to them as protein bars, energy bars, nutrition bars snack/meal bars or food bars, these food supplements share one important factor: convenience. (acefitness.org)
  • According to the United Nations Standing Committee on Nutrition,3 the primary health care (PHC) strategy and large-scale community-based nutrition programmes were primarily responsible for progress in nutrition during the 1980s. (who.int)
  • The new technique builds on an earlier strategy by researchers and pharmaceutical companies to remove proteins residing inside of a cell, and expands on this system to include proteins outside or on the surface of liver cells. (eurekalert.org)
  • They are also interested in collaborating with other researchers to help them test the removal of a wider array of disease-associated proteins. (eurekalert.org)
  • By tracing a protein tagged to glow fluorescent green as it migrates through individual neurons, from the cell body out through the branching dendrites, the researchers could see exactly which synapses-connections to other neurons-were involved when the mice learned to fear an electric shock. (technologyreview.com)
  • In addition, the researchers could completely turn off the entire tagged protein system by administering the drug doxycycline. (technologyreview.com)
  • Also, some people, especially those aged 70 and older, require extra protein to maintain adequate IGF-1 levels. (theepochtimes.com)
  • Significantly fewer inflammatory proteins were elevated in LLF following exposure to the middle dose compared to the high dose, with resolution by 1 m. (cdc.gov)
  • P. gingivalis HSP60 at 100 ng/l significantly downregulated the expression levels of VE‑cadherin and eNOS protein at 12 h in HUVECs. (spandidos-publications.com)
  • SIRT3-5 expression declined significantly in the hippocampus and frontal lobe, associated with increases in superoxide and fatty acid oxidation levels, and acetylated CPS-1 protein expression, and a reduction in MnSOD level. (frontiersin.org)
  • While SIRT6 expression declines significantly with age acetylated H3K9 protein expression is increased throughout the brain. (frontiersin.org)
  • Surprisingly, the protein preferentially lodged itself in one kind of synapse. (technologyreview.com)
  • For biological systems, Q peaks were first observed in protein from different perspectives [3,7,9,13,15,21-23] , the detailed molec- powders and attributed to 1H-14N spin pairs [9], which were also ular mechanism of the ubiquitous 1H-14N Q peaks in biological sys- thought to be of critical importance for the background 1H relaxa- tems has not been established. (lu.se)
  • G protein-coupled inwardly rectifying potassium channels are a type of G protein-gated ion channels because of this direct interaction of G protein subunits with GIRK channels. (wikipedia.org)
  • Based on primary sequence comparisons, β subunits are predicted to be modular structures composed of five domains (A-E) that are related to the large family of membrane-associated guanylate kinase proteins. (jneurosci.org)
  • When they do so, their molecular bonds (primarily the double bonds) may become disrupted. (aao.org)
  • DNA in chromatin is organized in arrays of nucleosomes 1 .Two copies of each histone protein, H2A, H2B, H3 and H4, are assembled into an octamer that has 145?147 base pairs (bp) of DNA wrapped around it to form a nucleosome core (of relative molecular mass 206K). (nature.com)