Recent longitudinal studies reveal that the most common form of the condition, late-onset idiopathic scoliosis, causes little physical impairment other than back pain and cosmetic concerns, even when untreated, with mortality rates similar to the general population. (wikipedia.org)
Older beliefs that untreated idiopathic scoliosis necessarily progresses into severe (cardiopulmonary) disability by old age have been refuted by later studies. (wikipedia.org)
Several candidate gene studies have found associations between idiopathic scoliosis and genes mediating bone formation, bone metabolism, and connective tissue structure. (wikipedia.org)
Several genome-wide studies have identified a number of loci as significantly linked to idiopathic scoliosis. (wikipedia.org)
In 2006, idiopathic scoliosis was linked with three microsatellite polymorphisms in the MATN1 gene (encoding for matrilin 1, cartilage matrix protein). (wikipedia.org)
Fifty-three single nucleotide polymorphism markers in the DNA that are significantly associated with adolescent idiopathic scoliosis were identified through a genome-wide association study. (wikipedia.org)
Research suggests that Posterior Spinal Fusion (PSF) can be used to correct the more severe deformities caused by adolescent idiopathic scoliosis. (wikipedia.org)
Idiopathic Scoliosis (IS) is the most common spinal deformity in adolescents, accounting for 80% of all spinal deformities. (biomedcentral.com)
However, the etiology remains uncertain in most cases, being identified as Adolescent Idiopathic Scoliosis (AIS). (biomedcentral.com)
Thoracic scoliosis1
The signs of scoliosis can include: Uneven musculature on one side of the spine Rib prominence or a prominent shoulder blade, caused by rotation of the rib cage in thoracic scoliosis Uneven posture Heart and lung problems in severe cases Calcium deposits in the cartilage end-plate and sometimes in the disc itself People who have reached skeletal maturity are less likely to have a worsening case. (wikipedia.org)
Congenital Scoliosis1
Among these conditions, VACTERL syndrome is notably associated with congenital scoliosis. (biomedcentral.com)
Neuromuscular3
An estimated 65% of scoliosis cases are idiopathic (cause unknown), about 15% are congenital, and about 10% are secondary to a neuromuscular disease. (wikipedia.org)
Other pathologies also appear to be related to the onset of EOS, in particular neuromuscular disorders ( syringomyelia or myelomeningocele), connective tissue disorders (Marfan Syndrome) and metabolic conditions (osteogenesis imperfecta) [ 3 ]. (biomedcentral.com)
Disorder2
Syringomyelia is a disorder of CSF and therefore understanding the pathogenesis of this enigmatic disorder is dependent on understanding CSF flow dynamics, biochemistry and factors that influence its absorption and The majority of CSF is produced by the four choroid plexuses (one in each ventricle of the brain), which circulates through the ventricular system and the subarachnoid spaces of the brain and spinal cord (9, 10). (marysfamilymedicine.org)
Rubinstein-Taybi syndrome (RTS) is a rare autosomal dominant disorder (prevalence 1:125,000) characterised by broad thumbs and halluces, facial dysmorphism, psychomotor development delay, skeletal defects, abnormalities in the posterior fossa and short stature. (biomedcentral.com)
Spondylolisthesis1
Dr. Munish C. Gupta specializes in spinal reconstructive surgery for both adults and children who need repair of spinal deformities resulting from scoliosis, kyphosis, spondylolisthesis and flatback syndrome. (munishguptaspine.com)
Syringomyelia is a condition characterised by fluid filed cavities (syrinxes or syringes) within the central spinal cord and the resulting damage produces clinical signs of pain and neurological deficits. (marysfamilymedicine.org)
Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). (lookformedical.com)
Diagnosis1
Since the increase in availability of magnetic resonance imaging (MRI), syringomyelia is an increasingly common diagnosis in veterinary medicine (1, 2) The most common cause of syringomyelia in the dog is Chiari-like malformation (Fig 1), a condition analogous to Chiari Type I and 0 malformation in humans (3, 4). (marysfamilymedicine.org)
Pathologies1
However this theory also leaves many unanswered questions and further study is In the dog syringomyelia is associated with a number of different pathologies with a common theme of CSF flow obstruction. (marysfamilymedicine.org)
Posterior1
MRI has the added advantage of depicting posterior cranial fossa anatomy and other abnormalities, such as syringomyelia and hydrocephalus. (medscape.com)
Surgery1
Somatosensory evoked potential monitoring can be difficult in a case of scoliosis surgery. (mhmedical.com)
Childhood1
2. Kjaer P, Wedderkopp N, Korsholm L, Leboeuf-Yde C. Prevalence and tracking of back pain from childhood to adolescence. (acr.org)
Genes1
The specific genes that contribute to development of scoliosis have not been conclusively identified. (wikipedia.org)
To show the prevalence estimates of BP, low back pain (LBP), mid back pain (MBP), neck pain (NP), and care-seeking because of BP at three different ages (9, 13 and 15 years) and how the BP reporting tracks over these age groups over three consecutive surveys. (acr.org)
Symptoms1
Symptoms associated with scoliosis can include: Pain in the back at the site of the curve, which may radiate to the legs Respiratory or cardiac problems in severe cases Constipation due to curvature causing "tightening" of the stomach, intestines, etc. (wikipedia.org)
Prevalence of Serious Pathology Among Adults with Low Back Pain Presenting for Chiropractic Care: A Retrospective Chart Review of Integrated Clinics in Hong Kong. (thephiladelphianewsjournal.com)
The prevalence of chief complaint of back pain was 8.6% (261/3042 patients). (acr.org)
People3
Scoliosis occurs in about 3% of people. (wikipedia.org)
So the prevalence of fibromyalgia may be as high as forty million people, just in the U.S. (discectomy.net)
The National Guidelines Clearinghouse was searched for existing guidelines pertinent to physical activity participation for people with scoliosis. (readkong.com)
Patients1
Physical activity and scoliosis 27 The focus of this study is (1) to systematically and critically review the literature to evaluate if physical activity is considered a contraindication for individuals with scoliosis and (2) to synthesize this literature and offer recommendations for participation in physical activities for patients with scoliosis. (readkong.com)
Search1
The initial search strategy combined the term scoliosis with a variety of terms relevant to the topic of study (Table 1). (readkong.com)
Risk1
About 38% of variance in scoliosis risk is due to genetic factors, and 62% is due to the environment. (wikipedia.org)
Journal of Chiropractic Medicine (2009) 8, 25-37 www.journalchiromed.com Is physical activity contraindicated for individuals with scoliosis? (readkong.com)
Web sites of respected organizations were searched for position/white papers on scoliosis and physical activity. (readkong.com)
The Internet review of 18 organizations yielded no previous guidelines or position papers for physical activity and scoliosis. (readkong.com)
Condition1
Scoliosis (PL: scolioses) is a condition in which a person's spine has a sideways curve. (wikipedia.org)
General population1
Prevalence is 8.4:100,000 in general population. (mhmedical.com)
Lead1
Some severe cases of scoliosis can lead to diminishing lung capacity, pressure exerted on the heart, and restricted physical activities. (wikipedia.org)