Present cartilage. Medical search. Frequent questions

In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, and is a structural component of many body parts including the rib cage, the neck and the bronchial tubes, and the intervertebral discs. (wikipedia.org)
The compression of the articular cartilage or flexion of the elastic cartilage generates fluid flow, which assists the diffusion of nutrients to the chondrocytes. (wikipedia.org)
The articular cartilage function is dependent on the molecular composition of the extracellular matrix (ECM). (wikipedia.org)
Due to the great stress on the patellofemoral joint during resisted knee extension, the articular cartilage of the patella is among the thickest in the human body. (wikipedia.org)
The mechanical properties of articular cartilage in load-bearing joints such as the knee and hip have been studied extensively at macro, micro, and nano-scales. (wikipedia.org)
The arthroscopic cartilage regeneration procedure or realignment osteotomy has been performed as a joint-conserving procedure in cases where conservative treatment for damaged articular cartilage and early osteoarthritis failed. (jameswyliemd.com)
Our group of scientists and clinicians has been continuously funded by the California Institute of Regenerative Medicine (CIRM) to develop a first-in class pluripotent stem cell-based therapy for focal articular cartilage lesions. (ca.gov)
The proposed candidate is a universal cell therapy designed to generate new articular cartilage in these defects and interrupt the cycle of degeneration. (ca.gov)
The work described in this proposal is designed to produce a universal treatment for articular cartilage lesions. (ca.gov)
Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes. (ca.gov)
This may be important for MSC-based repair of articular cartilage. (avma.org)
Sample Population -Articular cartilage and synovium with normal gross appearance from metacarpophalangeal and metatarsophalangeal joints of 8 horses (1 to 10 years of age). (avma.org)
This model imitates the degradation of articular cartilage after CCL rupture and has been used extensively in several animal models. (hindawi.com)
Prolonged, repetitive, and heavy loading of joints results in deformation of articular cartilage and chondrocytes and promotes the initiation and progression of OA [ 10 ]. (hindawi.com)
Autologous chondrocyte implantation produced hyalinelike cartilage, although its cellular organization was distinguishable from the surrounding articular cartilage. (unboundmedicine.com)
This is because articular cartilage of the type found in joints has a very poor ability to self-repair. (thenakedscientists.com)
This is similar to articular cartilage but with one important exception: it seems to have an enhanced potential for regeneration and growth. (thenakedscientists.com)
Studying the implanted nose cartilage also showed that it appeared to have remodelled itself to become more like articular cartilage and had increased the production of spongy molecules called glycosaminoglycans, which are highly abundant in normal cartilage. (thenakedscientists.com)
Nasal chondrocyte-based engineered autologous cartilage tissue for repair of articular cartilage defects: an observational. (thenakedscientists.com)
Moreover, the diffusion coefficient of Hexabrix was between 2.9 and 8.6 times lower than that of Visipaque that reflects the important effect of solute's charge on the transport through charged hydrated tissue such as articular cartilage. (tudelft.nl)
Slightly different diffusion coefficient observed within dilute and concentrated Visipaque baths suggested deviation from ideal Fickean behavior within articular cartilage. (tudelft.nl)
Knee articular cartilage injuries present a great challenge for musculoskeletal clinicians and scientists, leading to substantial morbidity and significant time lost from work and sport and even permanent disability. (researchgate.net)
If left untreated, knee articular cartilage injuries may lead to the development of widespread degenerative joint disease. (researchgate.net)
The cartilage covering, or articular cartilage, that covers the knee cap bone is the thickest cartilage covering in the entire human body. (sutterhealth.org)
and degeneration of articular cartilage. (cdc.gov)
It is well-established that meniscus root tears lead to decreased femorotibial contact area, increased peak contact pressures, and increased stress on the articular cartilage. (bvsalud.org)

These observations suggest that we may need to consider treatments for bone and cartilage separately. (hindawi.com)
The growth of bone and cartilage may be affected in children. (who.int)
Bone and cartilage damage occurred in animal studies on molnupiravir. (who.int)
Well-formed bone and cartilage are absent. (webpathology.com)

Cartilage is composed of specialized cells called chondrocytes that produce a large amount of collagenous extracellular matrix, abundant ground substance that is rich in proteoglycan and elastin fibers. (wikipedia.org)
Cartilage has limited repair capabilities: Because chondrocytes are bound in lacunae, they cannot migrate to damaged areas. (wikipedia.org)
The present work showed that ASCs do not encourage chemotaxis of bovine chondrocytes in 2-D culture. (queensu.ca)
Instead of forming collagen molecules, the abnormal COL2A1 protein builds up in cartilage cells (chondrocytes). (medlineplus.gov)
Cartilage is the slippery "anatomical Teflon" secreted by specialised cells called chondrocytes. (thenakedscientists.com)
This was treated with enzymes to release the cartilage-producing chondrocytes which were then incubated in a culture vessel containing a suitable growth medium for fourteen days to increase their numbers. (thenakedscientists.com)
To understand the mechanism of cartilage degeneration and remodeling, it is important to know the mechanical stimuli to chondrocytes for physiological loading conditions. (cdc.gov)
The purpose of the present study was to simulate numerically the location- and time-dependent stress-strain state and fluid pressure distribution in chondrocytes in unconfined compression tests under cyclic loading conditions. (cdc.gov)

Cartilage is a resilient and smooth type of connective tissue. (wikipedia.org)
Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondroblasts and begins secreting the molecules (aggrecan and collagen type II) that form the extracellular matrix. (wikipedia.org)
Processed chondrograft demonstrated good osteochondral integration, and the resulting tissue appeared to be hyaline cartilage. (unboundmedicine.com)
The applied cartilage surface processing method allows acceptable osteochondral integration, and the repair tissue appears to have good macroscopic and histologic characteristics. (unboundmedicine.com)
[ 49 ] Thus, a general classification of disease that combines elements of both of these systems is based on the number of skin lesions present and the number of bacilli found on tissue smears. (medscape.com)
Radiological findings and second-look arthroscopy however, indicate possible poor cartilage repair with evidence of fibrous infill and fissuring of the regenerative tissue following microfracture. (perfusion.com)
The nature of the cartilage repair that occurs for an osteochondral graft to become integrated with the native surround tissue is also of concern. (perfusion.com)
Cartilage - tissue that acts as a shock absorber between your joints - wears down as you age, per the Cleveland Clinic . (livestrong.com)
Cartilage is a tough, flexible tissue that makes up much of the skeleton during early development. (medlineplus.gov)
Dynamic Compressive Loading Improves Cartilage Repair in an in vitro Model of Microfracture: Comparison of Two Mechanical Loading Regimens on Simulated Microfracture Based on Fibrin Gel Scaffolds Encapsulating Connective Tissue Progenitor Cells. (chop.edu)
Efficacy of thermoresponsive, photocrosslinkable hydrogels derived from decellularized tendon and cartilage extracellular matrix for cartilage tissue engineering. (chop.edu)
The bright colors are created by polarized light and show the type of bone tissue and the attachment of the cartilage. (eurekalert.org)
The pain usually originates from the tissue around the kneecap including the tendons, bones and cartilage surfaces. (sutterhealth.org)
The reason that strengthening of the quadriceps muscle is effective is that it takes the pressure away from the knee cap cartilage and puts it into the muscular tissue. (sutterhealth.org)
Hyperplasia of bronchiole-associated lymphoid tissue (open arrow) and perivascular edema (solid arrow) are present. (cdc.gov)
With the increasing molecular definition of several types of collagen and recognition of the concentration of certain types in cartilage tissue, many skeletal dysplasias have now been defined as collagen abnormalities. (medscape.com)

Lubricin, a glycoprotein abundant in cartilage and synovial fluid, plays a major role in bio-lubrication and wear protection of cartilage. (wikipedia.org)
Studies have shown evidence of poor cartilage integration, with chondrocyte death at the periphery of the graft, possibly causing cyst formation due to synovial fluid ingress. (perfusion.com)
Because nitrogen bubbles are more present in the synovial fluid of older adults, you will tend to hear more snaps and pops as you age. (livestrong.com)
In-between there is cartilage and synovial fluid to keep the joint mobile. (eurekalert.org)
Hyaluronic acid (HA) which is present in our synovial fluid is also found in most body tissues. (sutterhealth.org)
Traditionally, complement is considered to be a component of blood but in fact all its components are present in the synovial fluid of joints. (lu.se)

Knee osteoarthritis (OA) is characterized by the morphological degeneration of cartilage. (spie.org)
Osteoarthritis is a common form of arthritis characterized by cartilage degeneration. (forbes.com)
In osteoarthritis, usually the cartilage thins in response to aging or joint injury (Figure 1). (forbes.com)
at the Wake Forest Institute of Regenerative Medicine examined cartilage deterioration in patients with osteoarthritis. (forbes.com)
Moreover, in order to extend the potential use of this technique to older people or those with degenerative cartilage pathologies like osteoarthritis, a lot more fundamental and pre-clinical research work needs to be done. (thenakedscientists.com)
Chronic inflammation contributes to cartilage degeneration during the progression of osteoarthritis (OA). (karger.com)
Once cartilage is lost in osteoarthritis, the disease cannot be reversed," said the study's lead author, Alexandra Gersing, M.D., from the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. (eurekalert.org)
Since cartilage loss cannot be reversed, it is important for people at risk of osteoarthritis or with early signs of the disease to slow the degeneration of cartilage. (eurekalert.org)
Osteoarthritis (OA) Osteoarthritis is a chronic disorder that causes damage to the cartilage and surrounding tissues and is characterized by pain, stiffness, and loss of function. (msdmanuals.com)
Osteoarthritis can be seen on X-ray images, but only once the condition has progressed so far that the cartilage in the joint has almost entirely worn away. (lu.se)

A tear of the meniscus of the knee cartilage can often be surgically trimmed to reduce problems. (wikipedia.org)
We present a method for knee cartilage segmentation in magnetic resonance images (MRI). (spie.org)
Our method incorporates the Hermite Transform to obtain a hierarchical decomposition of contours which describe knee cartilage shapes. (spie.org)
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Additional pieces of cartilage, known as the meniscus, further support the knee. (medicalnewstoday.com)
All of these protective pieces of cartilage keep the bones in the knee from rubbing together. (medicalnewstoday.com)
As the cartilage erodes, the bones of the knee joint start to rub together. (medicalnewstoday.com)
Doctors consider OA a "wear-and-tear" condition, because the use of the knee joint eventually wears out the cartilage. (medicalnewstoday.com)
Post-traumatic arthritis is a type of OA that stems from a previous injury to the knee joint, such as a sprain or a cartilage tear. (medicalnewstoday.com)
Knee-d new cartilage? (thenakedscientists.com)
Patients with knee injuries have been treated using cartilage grown from their own noses, Swiss doctors announced this week. (thenakedscientists.com)
Our findings confirm the safety and feasibility of cartilage grafts engineered from nasal cells to repair damaged knee cartilage. (thenakedscientists.com)
In the second part, Dr. Joachim Döring will present the results of a retrieval study on coated knee implants, by identifying types of damage - critical factors influencing the coating durability - and their correlation to the clinical performance. (anton-paar.com)
CHICAGO - Obese people who lose a substantial amount of weight can significantly slow down the degeneration of their knee cartilage, but only if they lose weight through diet and exercise or diet alone, according to a new MRI study presented today at the annual meeting of the Radiological Society of North America (RSNA). (eurekalert.org)
The reason the cartilage covering in this area is so thick is because the knee cap takes more pressure per unit of area than any other joint in the body. (sutterhealth.org)
With squatting and lunging activities up to six times the body weight is placed into the small bone of the knee cap and the cartilage. (sutterhealth.org)

My laboratory develops new technologies and approaches in utilizing naturally derived materials for the regeneration of soft-tissues such as skin, blood vessels, cartilage, tendons and ligaments. (dal.ca)
Joints are made up of many components, including muscles, tendons, ligaments and cartilage which need to be kept nourished and healthy. (health4youonline.com)
skin, cartilage, tendons and bones. (thehealthyplanet.com)

Compared to other connective tissues, cartilage has a very slow turnover of its extracellular matrix and is documented to repair at only a very slow rate relative to other tissues. (wikipedia.org)
Precarious botches linked to the present grafting treatments include osteonecrosis along with restricted combination between the grafted and host tissues. (scirp.org)
Therefore, it may be hypothesized that the use of cartilage in the promotion of endochondral regeneration of bones may leverage normal development and repair sequences resulting in a properly vascularized regenerate capable of integrating with the host tissues. (scirp.org)
Various tests have demonstrated that cartilage grafts are able to support the regeneration of vascularized and integrated bone tissues in vivo , while lineage tracing experiments have revealed graft derived regenerates. (scirp.org)
The condition tricks the body into thinking healthy tissues, such as protective cartilage, are harmful. (medicalnewstoday.com)
The typical pathologic manifestations of vitamin C deficiency, including poor wound healing, are noted in collagen-containing tissues and in organs and tissues such as skin, cartilage, dentine, osteoid, and capillary blood vessels. (medscape.com)
Another exciting discovery is that of the 'sixth base' in DNA i.e. hydroxylation of methylated cytosines (5mC) by enzymes leading to '5hmC' that is present in many tissues. (stanford.edu)
While the cartilage surfaces do not have any nerve endings, all the tissues around the kneecap cartilage (including the bones) do have nerve endings and can therefore produce pain. (sutterhealth.org)
When present, calcifications in soft tissues can be observed by means of this exam, but it is necessary to know the principles of interpretation in these radiographs, in order to identify these calcifications in the head and neck regions. (bvsalud.org)

Untreated cartilage defects often lead to joint pain and degeneration over time, often requiring joint replacement. (ca.gov)
Rationale: Efficient labeling methods for mesenchymal stem cells (MSCs) are crucial for tracking and understanding their behavior in regenerative medicine applications, particularly in cartilage defects. (bvsalud.org)

We found already that fibromodulin and cartilage oligomeric matrix protein (COMP) are potent activators of complement. (lu.se)

It is considered that the fundamental issue with the present approaches to bone grafting is the fact that they lead to bone regeneration by means of direct osteogenesis. (scirp.org)
As a result, there is a critical need for a strategy that can promote cartilage regeneration. (queensu.ca)
However, further experiments are necessary to assess the suitability of peptide-modified A-PTMC-PEG-PTMC-A/MCS hydrogels as a viable cartilage regeneration strategy. (queensu.ca)
Our research is geared towards applying reprogramming approaches towards musculoskeletal regeneration especially cartilage regeneration that remains an unmet medical need. (stanford.edu)
We are exploring the role of these novel DNA demethylation regulators in cartilage development, regeneration and disease. (stanford.edu)

Cartilage is classified in three types, elastic cartilage, hyaline cartilage and fibrocartilage, which differ in relative amounts of collagen and proteoglycan. (wikipedia.org)
Also, because hyaline cartilage does not have a blood supply, the deposition of new matrix is slow. (wikipedia.org)

Most cartilage is later converted to bone, except for the cartilage that continues to cover and protect the ends of bones and is present in the nose and external ears. (medlineplus.gov)
Where two bones meet, each bone meets has a protective covering of cartilage. (medicalnewstoday.com)
It happens when the protective cartilage that covers the bones wears away. (medicalnewstoday.com)
This is because,, except for some small bones at the bridge, the bulk of the nose is built from nasal cartilage. (thenakedscientists.com)
Cartilage, which is found at the end of bones, is a flexible and strong supportive material which is able to withstand heavy compression loads, often many times our own body weight. (health4youonline.com)
Glucosamine is naturally present in bones and cartilage and is considered a building block for joints and cartilage. (health4youonline.com)
Calcification of the growth cartilage at the end of the long bones continues, leading to the thickening of the growth plate. (medscape.com)
and as the cartilage breaks down, the two bones in the joint begin to rub against each other which can cause pain. (lu.se)

At present, treatment options for cartligage damage are very limited, ranging from trying to stimulate injured cartilage to regrow by injecting growth-factor and platelet-rich plasma, to grafting pieces of cartilage from other joints or even completely replacing a joint with a prosthesis. (thenakedscientists.com)

These mechanical properties include the response of cartilage in frictional, compressive, shear and tensile loading. (wikipedia.org)
However, only the overall response of cartilage to dynamic loading has been observed to date. (cdc.gov)

Cartilage growth thus refers to the matrix deposition, but can also refer to both the growth and remodeling of the extracellular matrix. (wikipedia.org)
In the present work, we have isolated and characterized the extracellular vesicles from human AD-MSC to investigate their role in the chondroprotective actions of these cells. (karger.com)
During cartilage injury, large quantities of complement factors are exposed to components of extracellular matrix, which are liberated from cartilage by proteases. (lu.se)

Over the last years, surgeons and scientists have elaborated a series of cartilage repair procedures that help to postpone the need for joint replacement. (wikipedia.org)
Histologic analysis confirmed the suppression of joint inflammation and showed prevention of cartilage and bone destruction after anti-IL-17 antibody therapy. (nih.gov)
Background Joint destruction in rheumatoid arthritis is comprised of cartilage and bone damage, which can be evaluated radiographically separately by the joint space narrowing (JSN) and erosion (ERO) scores. (bmj.com)
If this cartilage wears away, the joint becomes inflamed and painful. (forbes.com)
Osteochondritis dissecans occurs when a portion of the bone and its overlying cartilage loosen away from the rest of the joint surface. (medicalnewstoday.com)
Prof. Sander remarks: "It's truly amazing that the cartilage of the joint and apparently even the disc itself can survive for hundreds of millions of years. (eurekalert.org)
Importance of the Cervical Capsular Joint Cartilage Geometry on Head and Facet Joint Kinematics Assessed in a Finite Element Neck Model. (uwaterloo.ca)
In the present study, the capsular joint cartilage (CJC) geometry in a contemporary NM was enhanced (M50-CJC) based on literature data. (uwaterloo.ca)
But more than 2 million people, usually through injury, are diagnosed with cartilage-related joint conditions every year, and the problem is often long-lived. (thenakedscientists.com)
Joint supplements are formulated using various organic and natural ingredients to lessen pain and inflammation and increase cartilage synthesis. (healthstatus.com)
Make sure the key components that will be shown to be helpful are present when choosing the ideal joint supplement for your joint pain. (healthstatus.com)
Dr. Gersing and colleagues investigated cartilage degeneration and joint abnormalities over the course of 96 months in overweight and obese individuals who maintained stable weight and who lost weight via differing regimens. (eurekalert.org)
The clinical rationale for this project is based on the observation that cartilage contains molecules that initiate/enhance joint damage and inflammation in arthritis. (lu.se)

Goats have very dense bone and thick cartilage in the stifle joints making analysis of arthritic changes in goats difficult. (hindawi.com)
Healthy joints and cartilage are what help us to keep moving more easily. (health4youonline.com)
Solgar Glucosamine MSM Complex comes in a 2 tablets a day dosage, giving you a high level of these key ingredients to keep your joints and cartilage nourished. (health4youonline.com)

We used a multiple-incision technique (processed chondrograft) to increase cartilage graft surface. (unboundmedicine.com)

[ 2 ] The genetic defect in cartilage-hair hypoplasia has been confirmed to be mutations in the RMRP gene. (medscape.com)
The genetic defect in cartilage-hair hypoplasia has been identified as a mutation in the gene for RNAase RMRP, mapped to 9p12. (medscape.com)
This suggests a common cell proliferation defect in cartilage-hair hypoplasia. (medscape.com)
Cartilage-hair hypoplasia is a rare defect. (medscape.com)
This finding provides early evidence that ASCs may be unsuitable for promoting chondrocyte migration in a cartilage defect model. (queensu.ca)

Collagen bioinks are promising due to their cell-friendly properties but exhibit weak mechanical properties and slow gelation that present challenges for bioprinting applications. (worldcat.org)
The overall goal of this study is to develop improved collagen bioinks for cartilage bioprinting that exhibit improved mechanics and printability while maintaining cell-friendliness. (worldcat.org)
Type II collagen is a primary matrix protein of physeal and epiphyseal cartilage. (medscape.com)

One of the methods focuses on the hydrogen atoms in the aggrecan molecules, and the other focuses on the sodium ions that are present in healthy, aggrecan-rich cartilage. (lu.se)
Damage at molecular level - within the molecules of the cartilage - can be repaired through the ongoing renewal of the components of the cartilage. (lu.se)

Following the initial chondrification that occurs during embryogenesis, cartilage growth consists mostly of the maturing of immature cartilage to a more mature state. (wikipedia.org)
The division of cells within cartilage occurs very slowly, and thus growth in cartilage is usually not based on an increase in size or mass of the cartilage itself. (wikipedia.org)
G, which occurs in 30-50% of patients with cartilage-hair hypoplasia and causes an alteration in ribosomal processing. (medscape.com)
Pain mainly occurs during movement, but over time hip pain may be present even at rest. (lu.se)

We are developing techniques to create a decellularized porcine auricular (ear) cartilage scaffold that can be repopulated with human cells to successfully generate a construct with similar structural, compositional and mechanical properties to native auricular cartilage. (dal.ca)

Biological engineering techniques are being developed to generate new cartilage, using a cellular "scaffolding" material and cultured cells to grow artificial cartilage. (wikipedia.org)

A focal cartilage lesion has limited capacity to heal, and the repair modalities used at present are still unable to provide a universal solution. (unboundmedicine.com)
We hypothesized that pure cartilage graft with augmented osteochondral fusion capacity may be used for cartilage repair and we compared this method with other repair techniques. (unboundmedicine.com)
Compared with other methods, processed chondrograft was found to be similarly effective in cartilage repair. (unboundmedicine.com)
Biological adjuncts, in the form of platelet-rich plasma (PRP) and bone marrow aspirate concentrate ( BMAC ), have been investigated with regard to their potential in improving cartilage repair in both in vitro and in vitro settings. (perfusion.com)
These findings have been extrapolated to in vitro animal models, with results showing that both PRP and BMAC improve cartilage repair. (perfusion.com)
The basic science literature therefore establishes the proof of concept that biological adjuncts may improve cartilage repair when used in conjunction with reparative and replacement treatment strategies for osteochondral lesions of the talus. (perfusion.com)
Cartilage is unable to repair itself once the damage is extensive enough to be visible to the naked eye. (lu.se)
At an earlier stage, the cartilage has certain natural repair mechanisms. (lu.se)

Pure cartilage graft implantation appears to be a simple option, but it has not been applied widely as cartilage will not reattach easily to the subchondral bone. (unboundmedicine.com)
A thicker labral graft could support mechanical stability and protect cartilage better. (researchgate.net)

Autologous PRP and cartilage explants obtained from 6 healthy, adult, nonlactating Jersey-crossbred cows. (avma.org)

Almost all people have evidence of cartilage damage on kneecap cartilage when we perform arthroscopic surgery. (sutterhealth.org)

Cartilage does not contain blood vessels or nerves, hence it is insensitive. (wikipedia.org)

Efficient segmentation of cartilage is important for cartilage damage diagnosis and to support therapeutic responses. (spie.org)

To validate a technique for reproducible measurement of the osteochondroma cartilage cap with computed tomography (CT) and magnetic resonance (MR) imaging and to reevaluate the correlation of the thickness of the cartilage cap with pathologic findings to improve noninvasive differentiation of benign osteochondromas from secondary chondrosarcomas. (rsna.org)

The main proteoglycan in cartilage is aggrecan, which, as its name suggests, forms large aggregates with hyaluronan. (wikipedia.org)
Jonas Svensson is going to study two alternative measurement methods, both of which involve measuring the amount of aggrecan, an important protein in cartilage. (lu.se)

Indeed, when the cartilage is removed surgically, a dramatic decrease in inflammation and disease symptoms is observed. (lu.se)

Changes in bone were highly correlated between microcomputed tomography and radiographic analysis and changes in cartilage correlated well between urinary glycosaminoglycan levels and serum aggrecanase analyses. (hindawi.com)
The metabolic activity, percentage of dead cells, and glycosaminoglycan content of cartilage explants were measured with a resazurin-based assay, live-dead cell staining, and dimethylmethylene blue assay, respectively. (avma.org)

Therefore, cartilage damage is difficult to heal. (wikipedia.org)
Conclusions Cartilage damage appears to be the more clearly associated with irreversible physical disability than bony damage. (bmj.com)
The site forms a wheal on healthy skin, but not on skin where nerve damage is present. (medscape.com)

Basically, the cartilage that pads the discs in your spine gradually erodes as you get older. (scienceblogs.com)

The cartilage surfaces behind the kneecap are the thickest in the entire human body and usually begin to wear out after the age of 15. (sutterhealth.org)

This study supports application of a standardized measuring technique for improved distinction of benign osteochondromas from chondrosarcomas, with a cartilage cap thickness of 2 cm or greater as the determinant of chondrosarcoma. (rsna.org)
The proposed measuring technique allows accurate and reproducible measurement of cartilage cap thickness with both CT and MR imaging. (rsna.org)
Full-thickness cartilage discs (Ø = 8.5 mm, n = 3) were extracted from healthy equine femoral condyle (n = 2). (tudelft.nl)

Treatment with dexamethasone stimulated ALP activity and ALP mRNA, consistent with the progression of cartilage toward bone. (avma.org)

With this in mind, Basel University's Ivan Martin and his colleagues recruited ten patients with cartilage injuries to their knees. (thenakedscientists.com)
The manual provides additional guidance for coding amputations when other injuries are also present. (cdc.gov)

While pathogenetically the influx of immune and inflammatory cells signifies synovitis, its invasion into the adjacent bone and the consumption of cartilage constitute the destructive elements of the disease. (bmj.com)
Cartilage-hair hypoplasia (CHH), which is Online Mendelian Inheritance in Man (OMIM) disease number 250250, is an autosomal recessive inherited disorder that results in short-limb dwarfism associated with T-cell and B-cell immunodeficiency. (medscape.com)

C) In the trachea, a locally extensive focus of inflammation is present in the tracheal wall. (cdc.gov)

The ECM responds to tensile and compressive forces that are experienced by the cartilage. (wikipedia.org)

Application of PRP, AmpS, and PRP+AmpS treatments significantly reduced S aureus -induced chondrocyte death (ie, increased metabolic activity and cell viability staining) in cartilage explants, compared with untreated controls. (avma.org)

[ 15 ] The second consists of single nucleotide substitutions and other changes that involve at most 2 nucleotides in highly conserved regions of the gene.These are considered leaky mutations and result in variable expression of the gene, which may explain the variable phenotype seen in cartilage-hair hypoplasia. (medscape.com)
These latter mutations result in variable expression of the gene, which may explain the variable phenotype seen in cartilage-hair hypoplasia. (medscape.com)
The Hp 2-2 phenotype is present in 35% of whites and 50% of South Asians and East Asians and may help identify patients who are more prone to develop clinically significant vitamin C deficiency. (medscape.com)

Treatment effects were assessed relative to the findings for cartilage explants incubated in SF alone. (avma.org)

[ 17 ] In studies from Makitie et al, defective in vitro colony formation in all myeloid lineages was present, including erythroid, granulocyte-macrophage, and megakaryocyte colony formation. (medscape.com)

Anatomy65

Organisms7

Diseases31

Chemicals and Drugs77

Analytical, Diagnostic and Therapeutic Techniques and Equipment43

Phenomena and Processes25

Disciplines and Occupations2

Technology, Industry, Agriculture3

Information Science5

Health Care2

Articular26

Bone and cartilage4

Chondrocytes8

Tissue16

Synovial6

Osteoarthritis10

Knee28

Tendons3

Tissues9

Defects2

Oligomeric matrix protein1

Regeneration5

Hyaline cartilage2

Bones8

Pieces of cartilage1

Response of cartilage2

Extracellular3

Joint13

Joints3

Increase cartilage1

Defect5

Collagen3

Molecules2

Occurs4

Porcine1

Developed to generate new1

Repair8

Graft2

Autologous1

Arthroscopic1

Blood vessels1

Diagnosis1

Computed tomography1

Aggrecan2

Surgically1

Glycosaminoglycan2

Damage3

Erodes1

Thickest1

Thickness3

Progression1

Injuries2

Disease2

Inflammation1

Compressive1

Viability1

Phenotype3

Findings1

Vitro1