• Overall, COP chemotherapy causes complete remission in about 70% of dogs with lymphoma for a median of 130 days. (vin.com)
  • Complete remission was achieved in 84% of dogs for a median of about 9 months. (vin.com)
  • [ 3 ] Approximately 90% of patients with GPA respond to cyclophosphamide, with approximately 75% experiencing complete remission. (medscape.com)
  • This stage is known as a complete remission. (submityourassignment.com)
  • The Japan Adult Leukemia Study Group conducted the ALL-87 study to determine whether response-oriented induction therapy and intensive consolidation and maintenance/intensification therapies could increase complete remission (CR) rate and survival in adult acute lymphoblastic leukemia (ALL). (elsevierpure.com)
  • Complete remission (CR) was obtained in 97 (83.6%) patients (90.2% in patients of less than 50 years of age and 67.6% in patients 50 years of age or older). (elsevierpure.com)
  • Thirty-six (86%) achieved first complete remission (CR1) at the end of induction, of which 28 underwent BM transplantation (BMT). (johnshopkins.edu)
  • We describe a case of Stevens-Johnson syndrome (SJS) that was induced by a single dose of pembrolizumab and successfully treated with steroids, leading to complete remission of lung cancer during the monitoring of immune response indices, including Nr4a1 mRNA. (biomedcentral.com)
  • After the disappearance of the SJS symptoms, complete remission of cancer was achieved and was maintained for more than 1 year. (biomedcentral.com)
  • The immune responses involving Nr4a1 suppression might relate to complete remission of lung cancer in this case, despite causing SJS, which may be attributed to synergistic effects from pembrolizumab treatment and intervention with steroids. (biomedcentral.com)
  • Adalimumab (ADA) is applied to induce remission in patients with Crohn's disease (CD) naïve to chimeric anti-tumor necrosis factor-α (anti-TNF-α), infliximab or patients with loss of response to scheduled maintenance infliximab. (adacyte.com)
  • Between December 2010 and February 2012, 5 consecutive cases with refractory CD were treated with intensive GMA (2 sessions per week) plus ADA to induce remission. (adacyte.com)
  • These drugs are commonly high dose steroids (prednisolone) and additional treatment with drugs such as cyclophosphamide or methotrexate may be given. (vasculitis.org.uk)
  • Since introduced by Fauci et al in the 1970s, oral cyclophosphamide in combination with high-dose glucocorticoids (ie, prednisone 1mg/kg/day) has been the criterion standard for induction of remission in AAV. (medscape.com)
  • Eventually, intravenous cyclophosphamide was investigated as an alternative to oral cyclophosphamide in an effort to decrease treatment-associated toxicities, and, while the emphasis has been placed on optimizing treatment by minimizing exposure to cyclophosphamide and seeking alternative comparable therapies, the combination of cyclophosphamide (intravenous or oral) and glucocorticoids remained the recommended therapy for induction of remission in generalized/severe GPA for years. (medscape.com)
  • In 2011, however, the US Food and Drug Administration (FDA) approved the use of rituximab (a monoclonal antibody that targets B cells), in combination with glucocorticoids, as an alternative to cyclophosphamide for induction of remission in AAV (GPA and microscopic polyangiitis). (medscape.com)
  • The efficacy of intensive immunosuppressive therapy with agents such as cyclophosphamide (CYC) or rituximab (RTX) has been established as a remission-inducing therapy in patients with organ/life-threatening AAV 1-5 and is recommended as a conventional therapy. (bmj.com)
  • In ocular inflammation, they are used as steroid-sparing agents to control the inflammation with a target for durable remission and prevention of sight-threatening complications of uveitis. (aao.org)
  • long-term dependence on steroid therapy, if more than 5-10mg/day of prednisolone is required to keep the disease in control- steroid-sparing IMT is indicated. (aao.org)
  • The concomitant oral steroid dose could be tapered from 50?mg to 5?mg oral prednisolone/day time. (euromedh2020.com)
  • Steroid-refractory disease may be defined as active disease in spite of an adequate dose and duration of prednisolone and steroid dependence as a relapse when the steroid dose is reduced below 20 mg/day, or within 6 weeks of stopping steroids. (ulcertalk.com)
  • Middle ear canal and eosin photomicrograph 40: not be quickly and natural steroid hormones 4 and prednisolone. (myjuicecup.com)
  • the median time from remission to relapse was 13 months and 15 months, respectively (P = 0.023, log rank test). (nih.gov)
  • The 6-month remission rate (RR 1.09, 95% CI 0.86 to 1.38, p=0.48), the 6-month ANCA negativity (RR 1.31, 95% CI 0.91 to 1.90, p=0.15) and the long-term relapse rate (RR 1.36, 95% CI 0.80 to 2.31, p=0.26) were all similar between the two treatments. (bmj.com)
  • Remission Induction therapy - Usually requires a combination of immunosuppressive drugs to control the inflammation. (vasculitis.org.uk)
  • This shows a positive response to the corticoid treatment, given that lower SUV max values mean that there is a remission in the colonic inflammation. (databasefootball.com)
  • Olivry t, acidophilus is very dire, and inflammation needed in the induction of kidney disease? (myjuicecup.com)
  • Remission Maintenance therapy - Once the disease is controlled or in remission (indicated by improved symptoms and blood tests), the treatment is changed (usually after several months) and maintenance therapy is commenced. (vasculitis.org.uk)
  • Patients may have intermittent symptoms with varying periods of remission. (aafp.org)
  • Two rituximab infusions (375?mg/m2 IV) plus a solitary additive dose of 100?mg prednisolone IV at 4\week WZ811 intervals induced remission of polyarthritis and additional symptoms in both instances. (euromedh2020.com)
  • Prednisolone will be used to control your symptoms and get you well while the other medicine takes effect. (ulcertalk.com)
  • Tzaneva s, diarrhea, 6/13 cats requiring ongoing allergy symptoms with a median induction of induction of cats: epilepsy. (myjuicecup.com)
  • Two months after induction therapy with adalimumab, the CDAI decreased from 175 to 107 without side effects. (adacyte.com)
  • Typically, chemotherapy treatment is given to the patient in cycles and in phases: induction, consolidation and maintenance therapy. (submityourassignment.com)
  • Induction therapy is the initial treatment of the chemotherapy that aimed to destroy as many leukemia cells as possible, achieve normal level of blood counts and treat acute lymphocytic leukemia into remission. (submityourassignment.com)
  • Patients were randomly allocated either to receive or not, intrathecal chemotherapy on day 8 of the induction therapy. (elsevierpure.com)
  • One example is a human study in which researchers discovered that higher levels of the antioxidant selenium in the blood of patients with aggressive B-cell non-Hodgkin's lymphoma correlated with increased achievable doses of anthracycline based chemotherapy, better treatment response, achievement of long term remission, and longer overall survival. (pinestreetfoundation.org)
  • Anakinra rapidly induced remission in these three individuals,1,2 whereas rituximab was effective in both of our TNF inhibitor (etanercept and infliximab) resistant individuals. (euromedh2020.com)
  • However, some reports of serious infectious complications, such as septicaemia with anakinra treatment, have appeared.9 To our knowledge this is the first report of the successful induction of remission with rituximab in AOSD. (euromedh2020.com)
  • To evaluate the long-term frequency of disease remissions and the progression of joint damage in patients with early rheumatoid arthritis (RA) who were initially randomized to 2 years of treatment with either a combination of 3 disease-modifying antirheumatic drugs (DMARDs) or a single DMARD. (nih.gov)
  • The MTX regimen used in the present study was less effective for induction of remission in patients with extensive disease and pulmonary involvement and was associated with more relapses than the CYC regimen after termination of treatment. (nih.gov)
  • Most veterinary oncologists agree that unless palliation rather than extended remission is the goal of therapy, single agent treatment of lymphoma should be avoided. (vin.com)
  • Since the 1980s prednisolone and azathioprine have been used for induction and remission of the disease and remain the mainstay of treatment. (e-cmh.org)
  • In cases unresponsive to conventional treatment, achieving disease remission can be difficult and institutions may vary in their experience and management of this challenging patient group. (e-cmh.org)
  • There are two phases in the treatment of vasculitis - "Remission Induction" therapy (getting the disease under control) and "Remission Maintenance" therapy (keeping the disease under control). (vasculitis.org.uk)
  • The aim of treatment is to keep the disease process in remission. (vasculitis.org.uk)
  • Additionally, treatment recommendations are different for induction of remission and maintenance of remission. (medscape.com)
  • Patients in both treatment arms receive a 26-week prednisolone taper regimen. (biomedcentral.com)
  • At week 10 post ADA treatment, clinical remission together with normal CRP levels were achieved in all 5 cases, while SES-CD scores reflected marked improvement in 3 cases and partial improvement in 2 cases who had extensive deep longitudinal CD lesions. (adacyte.com)
  • Recently, two case studies reported the successful induction of remission with the interleukin 1 receptor antagonist anakinra in refractory AOSD.1,2 In addition to the patient reported by Aarntzen em et al /em ,1 two of the six individuals WZ811 reported on by Fitzgerald em et al /em 2 had been resistant to etanercept treatment. (euromedh2020.com)
  • Then you will gradually reduce your dose of prednisolone, allowing the other medicine, called a maintenance treatment, to take over and keep you in remission. (ulcertalk.com)
  • On the other hand, it was necessary to validate the model, so a corticoid commonly used in clinical practice (Prednisolone) was administered to a group of animals with IBD, and then compared to the group of animals without treatment. (databasefootball.com)
  • On day 3 after induction, the corticosteroid treatment was started, and from days 7-13. (databasefootball.com)
  • On Day 21 of treatment, SJS appeared, and the patient was treated with prednisolone 60 mg/day, which was gradually tapered off. (biomedcentral.com)
  • The prednisolone is usually reduced to a very low dose. (vasculitis.org.uk)
  • Patients who do not achieve remission by week 12 experience a flare after remission or cannot adhere to the prednisolone tapering will enter the escape arm and receive prednisolone at a dose determined by the investigator's clinical judgment. (biomedcentral.com)
  • The average dose of concomitant prednisolone required was 30?mg daily. (euromedh2020.com)
  • The patient should be observed closely for signs that the dose may need to be altered, such as changes in clinical status resulting from disease remissions or exacerbations. (who.int)
  • There is anecdotal evidence of successful induction and maintenance of remission with the monoclonal anti-IL-17A antibody secukinumab. (biomedcentral.com)
  • How long people with vasculitis need to remain on remission maintenance therapy is very variable and will need to be discussed on an individual basis with the medical team helping look after the patient. (vasculitis.org.uk)
  • Azathioprine and other immunosuppresant drugs can be used as adjunctive therapy for active Crohn's disease and may help to maintain remission. (aafp.org)
  • We conducted a systematic review and meta-analysis to assess the efficacy of MMF as a remission induction therapy in patients with AAV comparing it with the efficacy of CYC. (bmj.com)
  • MMF may be an alternative remission induction therapy in patients with non-life-threatening AAV. (bmj.com)
  • The residual leukemia was quantified after 2 (MRD-D15, n = 29) and 4 weeks (MRD-PI, n = 42) of induction therapy with a precise and reproducible clone-specific PCR technique. (prinsesmaximacentrum.nl)
  • Induction therapy is usually very intense and lasts about one month. (submityourassignment.com)
  • Response-oriented induction therapy produced a high CR rate, but fairly intensive consolidation and maintenance/intensification chemotherapies resulted in only a marginal effect on DFS in adult ALL. (elsevierpure.com)
  • This study was to investigate the efficacy of intensive GMA in combination with ADA as remission induction therapy in cases of CD refractory to medications including anti-TNF-α therapies. (adacyte.com)
  • In these 5 cases with medication-refractory CD, combination therapy with intensive GMA followed by 5 ADA shots appeared to be an effective and safe intervention for inducing clinical remission. (adacyte.com)
  • At 6 months, the remission rate in patients treated with MTX (89.8%) was not inferior to that in patients treated with CYC (93.5%) (P = 0.041). (nih.gov)
  • In the MTX group, remission was delayed among patients with more extensive disease (P = 0.04) or pulmonary involvement (P = 0.03). (nih.gov)
  • Some patients can achieve a long-term biochemical remission and never need retreatment. (medscape.com)
  • The primary endpoint is the proportion of patients in sustained remission until week 28 in the secukinumab group compared to the proportion of patients in the placebo group. (biomedcentral.com)
  • A new study examined the independent effects of excess weight and obesity on achieving sustained remission in rheumatoid arthritis (RA) patients. (the-rheumatologist.org)
  • Researchers found that within three years of RA diagnosis, overweight and obese patients were significantly less likely to achieve sustained remission than patients with healthy body mass indices (BMIs). (the-rheumatologist.org)
  • Cause the body to shut down its natural production of testosterone in the for induction of remission in patients with severe activity at 8 weeks. (onevpn.com)
  • Clinical and endoscopic remission of the patient's CD was maintained with salazosulfapyridine (3000 mg/day) and occasional prednisolone (≤20 mg/day) from 2001 to 2010. (adacyte.com)
  • The long-term effectiveness was assessed by recording the frequency of remissions and the extent of joint damage seen on radiographs of the hands and feet obtained annually up to 5 years. (nih.gov)
  • You are doing all that you can to avoid 'triggers' but sometimes the trigger just can't be identified, and so many dogs have an AI disease when they are young and do achieve long term remission. (cimda.co.uk)
  • The good news is, SRMA is not life threatening and if treated correctly, long term remission can be reached. (cimda.co.uk)
  • Cyclosporine-A versus prednisolone for induction of remission in auto-immune hepatitis: interim analysis report of a randomized controlled trial. (frigger-consult.de)
  • About 98 to 99 percent of children with newly diagnosed acute lymphoblastic leukemia attain initial complete remissions(absence of detectable leukemic cells by microscopic examination) in four to six weeks. (submityourassignment.com)
  • After 2 years, the DMARD and prednisolone treatments became unrestricted, but were still targeted toward remission. (nih.gov)
  • Methylprednisolone sodium phosphate and neurological changes, dogs: chemical and prednisolone, or exacerbate existing infections. (myjuicecup.com)
  • For our study, we chose the TNBS animal model, which consists of the induction of an experimental colitis through the use of a haptenizing agent called 2,4,6-trinitrobenzenesulfonic acid. (databasefootball.com)
  • Concomitant oral prednisolone dosages could be tapered to 5?mg/day time and remission maintained with MTX and ciclosporin, respectively during follow up. (euromedh2020.com)
  • Often you will be prescribed prednisolone at the same time as other medicines. (ulcertalk.com)
  • The primary end point was the remission rate at 6 months (noninferiority testing). (nih.gov)
  • It is such good news that Elsie has reached remission and has been well for 8 months. (cimda.co.uk)