• Metformin is effective in preventing type 2 diabetes in high-risk non-pregnant individuals, but its effect when commenced in the postnatal period is not known. (birmingham.ac.uk)
  • The Edinburgh Postnatal Depression Scale is a handy checklist easily found online that can provide a quick screening for post-natal depression. (islamicity.org)
  • The PREMILOC trial was a double-blind, multicenter, randomized, placebo-controlled trial designed to test just that concept by introducing a low dose of hydrocortisone within 24 hours of birth. (allthingsneonatal.com)
  • METHODS AND ANALYSIS: Optimising health outcomes with Metformin to prevent diAbetes After pregnancy (OMAhA) is a multicentre placebo-controlled double-blind randomised feasibility trial, where we will randomly allocate 160 postnatal women with gestational diabetes treated with medication to either metformin (intervention) or placebo (control) tablets to be taken until 1 year after delivery. (birmingham.ac.uk)
  • Although there is evidence that consumption of a high glucosinolate diet is linked with reduced incidence of chronic diseases, future large-scale placebo-controlled human trials including standardized glucosinolate supplements are needed. (frontiersin.org)
  • In placebo-controlled studies, genital warts have cleared spontaneously without treatment in 20%-30% of patients within 3 months. (cdc.gov)
  • Metabolomic profiles of metformin in breast cancer survivors: a pooled analysis of plasmas from two randomized placebo-controlled trials. (who.int)
  • Effects of prenatal perineal massage and kegel exercises on the integrity of postnatal perine. (evidencebasedbirth.com)
  • We reviewed the actual literature on the potential contributing role of prenatal and early postnatal vitamin D deficiency in ASD etiopathogenesis, at both genetic and environmental levels, and the possible effect of vitamin D supplementation in autistic children. (current-pharmaceutical-design.com)
  • While most prenatal multivitamins contain an array of vitamins and minerals to nourish both mom and baby, most lack adequate concentrations of the nutrients that are specific to postnatal health concerns. (payitforwardfertility.org)
  • Impact of prenatal and postnatal household air pollution exposure on lung function of 2-year old Nigerian children by oscillometry. (uchicago.edu)
  • Cord blood metabolites and rapid postnatal growth as multiple mediators in the prenatal propensity to childhood overweight. (who.int)
  • The Durham Connects program was developed in collaboration with community leaders as a brief, universal, postnatal nurse home visiting intervention designed to screen for risk, provide brief intervention, and connect families with more intensive evidence-based services as needed. (nhvrc.org)
  • All 4777 resident births in Durham, North Carolina across 18 months were randomly assigned, with even birth date families to intervention and odd birth date families to control. (nhvrc.org)
  • In general, however, the optimal window of success for nutritional intervention to best support brain development is in late fetal and early postnatal life. (vitamindwiki.com)
  • Andrew MJ, Parr JR, Montague-Johnson C et al (2018) Neurodevelopmental outcome of nutritional intervention in newborn infants at risk of neurodevelopmental impairment: the Dolphin neonatal double-blind randomized controlled trial. (vitamindwiki.com)
  • The experimental group received the UIW app intervention and oral pelvic floor muscle training (PFMT) instructions, whereas the control group received oral PFMT instructions alone. (jmir.org)
  • The app-based UI self-management intervention (UIW) effectively improved UI symptom severity, quality of life, self-efficacy with PFMT, and knowledge of UI during the late pregnancy and early postnatal periods. (jmir.org)
  • Previously, the research group performed a pilot study, the Self-Management of Postnatal Antihypertensive Treatment ( SNAP-HT ) trial and the SNAP- extension trial , which compared a BP self-monitoring intervention with usual care in 91 women with gestational hypertension or preeclampsia requiring postnatal antihypertensive treatment. (medscape.com)
  • Following a baseline visit at day 1 to 6 after delivery, while in the postnatal ward, the patients were randomly assigned 1:1 to the intervention group (112 women) or usual care group (108 women). (medscape.com)
  • Starting on feeding day 2, extremely preterm infants 28 weeks or younger fed maternal or donor milk were randomized to receive either a diet fortified with a human-based product (intervention group) or a standard, unfortified diet (control group). (aap.org)
  • PRIMAL Study participants were enrolled from two antenatal care clinics and randomized 1:1 to an intervention or control arm. (biomedcentral.com)
  • We developed a complex intervention (SMARThealth Pregnancy) involving mobile clinical decision support for CHWs and evaluated it in a pilot cluster randomized controlled trial (cRCT). (jmir.org)
  • The evaluation involved a total of 200 pregnant women, equally randomized to intervention or enhanced standard care (control). (jmir.org)
  • Results suggest a possible improvement in mean hemoglobin (anemia) in the intervention group, although an adequately powered trial is needed. (jmir.org)
  • The control group did not receive any intervention. (rrh.org.au)
  • Pregnancy outcomes and ethanol cook stove intervention: A randomized-controlled trial in Ibadan, Nigeria. (uchicago.edu)
  • CDC] Centers for Disease Control and Prevention. (cdc.gov)
  • 09/24/1993 SUGGESTED CITATION Centers for Disease Control and Prevention. (cdc.gov)
  • These trials should evaluate long-term neurodevelopmental and pulmonary outcomes, in addition to short-term outcomes. (cochrane.org)
  • Ogden syndrome (OGDNS) is an X-linked neurodevelopmental disorder characterized by postnatal growth failure, severely delayed psychomotor development, variable dysmorphic features, and hypotonia. (nih.gov)
  • 2020). Antenatal perineal massage benefits in reducing perineal trauma and postpartum morbidities: a systematic review and meta-analysis of randomized, controlled trials. (evidencebasedbirth.com)
  • In rural India, community health workers (CHWs) deliver antenatal and postnatal care. (jmir.org)
  • SMARThealth Pregnancy is an innovative model of home-based care for high-risk pregnant women during the transitions between antenatal and postnatal care and adult health services. (jmir.org)
  • Sandra Krause, Program Director of Reproductive Health at the Women's Refugee Commission, explained that maternal newborn health funding is typically allocated to antenatal care, postnatal care and nutrition programs, while little is designated for emergency obstetric and newborn care, family planning and safe abortion care. (mhtf.org)
  • Interventions with only a postnatal component were more beneficial (0.76, 0.58 to 0.98) than interventions that incorporated an antenatal component. (bmj.com)
  • Postnatal depression and caregiving difficulties adversely affect mothers, infants, and later childhood development. (jmir.org)
  • A British case-control study of mothers from 4 general practices found a 3-fold higher incidence of depression within 5 weeks after childbirth. (jabfm.org)
  • Ediz Ç, Kavak Budak F. Effects of psychosocial support-based psychoeducation for Turkish pregnant adolescents on anxiety, depression and perceived social support: a randomized controlled study. (rrh.org.au)
  • Objective To assess the effects of psychosocial and psychological interventions compared with usual antepartum, intrapartum, or postpartum care on the risk of postnatal depression. (bmj.com)
  • Study selection All published and unpublished randomised controlled trials of preventive psychosocial or psychological interventions in which the primary or secondary aim was a reduction in the risk of postnatal depression. (bmj.com)
  • relative risk 0.81, 95% confidence interval 0.65 to 1.02), these results suggest a potential reduction in postnatal depression. (bmj.com)
  • Identifying women "at risk" assisted in the prevention of postnatal depression (0.67, 0.51 to 0.89). (bmj.com)
  • Conclusions Diverse psychosocial or psychological interventions do not significantly reduce the number of women who develop postnatal depression. (bmj.com)
  • Postnatal depression is a major health issue for many women from diverse cultures. (bmj.com)
  • Women who have postnatal depression are significantly more likely to experience future episodes of depression, 5 and infants and children are particularly vulnerable because of impaired maternal-infant interactions and negative perceptions of infant behaviour. (bmj.com)
  • The cause of postnatal depression remains unclear, 6 with extensive research suggesting many contributory factors. (bmj.com)
  • 3 7 9 11 - 15 A comprehensive review suggested that in women with postnatal depression, psychosocial and psychological treatment may be suitable. (bmj.com)
  • 16 As such, it is theoretically possible that these interventions may also prevent postnatal depression, as many of the known risk factors are present during pregnancy and the immediate postpartum period. (bmj.com)
  • There have been two critical reviews of preventive trials 17 18 and one systematic review that examined diverse interventions to reduce "probable depression" in the postnatal period. (bmj.com)
  • I assessed the effects of such interventions compared with usual antepartum, intrapartum, or postpartum care on the risk of postnatal depression. (bmj.com)
  • From fetal anomalies with planned intrauterine or postnatal surgery to screening for complications of pregnancy such as pre-eclampsia, fetal growth restriction, and preterm birth, most fetal diagnoses present relevant implications and benefits of timely preventive interventions. (mdpi.com)
  • Now, a randomized controlled trial has proven definitively that fetal surgery can help certain patients before birth. (ucsf.edu)
  • The surgical procedures evaluated in the current trial were developed at the UCSF Fetal Treatment Center under the direction of Michael Harrison, MD, a UCSF professor emeritus considered the "Father of Fetal Surgery. (ucsf.edu)
  • Alexander EK, Pearce EN, Brent GA et al (2017) 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. (vitamindwiki.com)
  • In a randomized trial of 220 women with preeclampsia or gestational hypertension, those who took daily postpartum BP readings and received clinician-guided advice for titrating antihypertensives had a 5 mm Hg lower average diastolic BP at 9 months, compared with those receiving usual care. (medscape.com)
  • Jamie Kitt, DPhil, from the University of Oxford, Oxford, England, presented these findings from the Physicians Optimized Postpartum Hypertension Treatment ( POP-HT ) clinical trial at the American Heart Association (AHA) 2023 Scientific Sessions. (medscape.com)
  • The 'Primary HIV Prevention among Pregnant and Lactating Ugandan Women' (PRIMAL) randomized controlled trial aimed to assess an enhanced counseling strategy linked to extended postpartum repeat HIV testing and enhanced counseling among 820 HIV-negative pregnant and lactating women aged 18-49 years and 410 of their male partners to address the first pillar of the WHO Global Strategy for the Prevention of Mother-to-Child HIV transmission (PMTCT). (biomedcentral.com)
  • All trials recruited pregnant women or new mothers less than six weeks postpartum. (bmj.com)
  • And like DMPA, NET-EN may also be given immediately after a spontaneous or induced abortion or immediately postpartum, regardless of breastfeeding status. (msdmanuals.com)
  • 1999). Randomized controlled trial of prevention of perineal trauma by perineal massage during pregnancy. (evidencebasedbirth.com)
  • Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
  • The Sustainable Development Goals, set by the United Nations in 2015, identify prevention and control of noncommunicable diseases as core priorities. (who.int)
  • A total of 150 infants were randomized between 2020 and 2022. (aap.org)
  • We can compare trials by doing meta analyses or systematic reviews and perhaps that is where we will head with this study although given that different steroids will have been used (thinking dexamethasone as in the DART study) this will always be left open to question. (allthingsneonatal.com)
  • Yoga for nervousness: a systematic assessment and meta-evaluation of randomized controlled trials. (mybeautifulhealthyskin.com)
  • Tim has broad experience of methodologies used in applied health services research including: randomised controlled trials, systematic review, surveys, qualitative research, economic analyses, systematic reviews, use of large routine datasets in health services research and quasi-experimental studies. (nottingham.ac.uk)
  • Over the last decade he has become more involved in systematic review and interventional studies, clinical trials and applied health research using a broad range of complementary research methods and involving substantial local and national collaborations. (nottingham.ac.uk)
  • Effect of two different doses of parenteral amino acid supplementation on postnatal growth of very low birth weight neonates, a randomized controlled trial. (umassmed.edu)
  • This brief, universal, postnatal nurse home visiting program improves population-level infant health care outcomes for the first 12 months of life. (nhvrc.org)
  • We do not know how effective levothyroxine is in treating persons with subclinical hypothyroidism, as trials have been too small to detect any clinically relevant improvements in outcomes. (aafp.org)
  • Conclusions: Standardized methodologies, such as our PPTR approach, could facilitate unbiased efficacy outcome determinations, improve discrimination between outcomes that are related and unrelated to regimen efficacy, and enhance the ability to conduct pooled analyses of contemporary trials. (cdc.gov)
  • Well-designed, adequately powered, randomized, multi-center trials are needed to address the efficacy and safety of prostanoids and their analogues in the treatment of PPHN. (cochrane.org)
  • Further Randomized Controlled Trials studies carried out during pregnancy and early infancy are necessary for better understanding the possible contribution of vitamin D deficiency in the etiopathogenesis of autism and the potential efficacy of the hormone supplementation in the improvement of ASD core symptoms. (current-pharmaceutical-design.com)
  • Angulo-Barroso RM, Li M, Santos DCC et al (2016) Iron supplementation in pregnancy or infancy and motor development: a randomized controlled trial. (vitamindwiki.com)
  • Vitamin C supplementation in very preterm infants: A randomised controlled trial. (otago.ac.nz)
  • Online group-based nurse-led interventions have the potential to help address this problem by providing large numbers of mothers with access to professional and peer support during the postnatal period. (jmir.org)
  • Dans les pays en développement, le manque de personnel qualifié, l'analphabétisme et les problèmes d'observance rendent les interventions sanitaires encore plus complexes. (who.int)
  • WHO urges Member States as well as international, regional and national health institutions to regularly report on AMR status to serve as an evidence base for informing strategies and devising efficient preventive and control interventions. (who.int)
  • Mothers were recruited at the time they were contacted for the postnatal health check offered to all mothers in South Australia. (jmir.org)
  • As such, it appears that support for mothers during the postnatal period, provided using mobile phone technology, has the potential to be an important addition to existing services. (jmir.org)
  • In this article, we'll review the 5 best postnatal multivitamins available and discuss how each product plays a crucial role in terms of optimizing breast milk quality and meeting the nutritional needs of mothers who may suffer from postnatal depletion. (payitforwardfertility.org)
  • Mama Bird Postnatal Multi+ protects new mothers from vaginal infections through its inclusion of Lactobacillus acidophilus. (payitforwardfertility.org)
  • Majka is a worldwide leader in lactation supplements and postnatal vitamins and its Replenishing Powder provides new mothers with an easy, on-the-go solution to meeting their nutritional needs. (payitforwardfertility.org)
  • One controlled randomized trial on a series of 30 patients compared the effectiveness of cyproterone acetate (CPA) versus hydrocortisone. (clinicalgenome.org)
  • Randomized controlled trials evaluating the effectiveness of tranexemic acid and fibrinogen concentrate on PPH are currently underway, with results expected within the next few years. (medscape.com)
  • Qualitative work on women's experiences of postnatal mental health problems has sampled women within particular diagnostic categories so not looked at the range of potential psychological problems. (biomedcentral.com)
  • A review of the epidemiology, public health importance, treatment and control of head lice. (mcmaster.ca)
  • Supervises PhD and Masters' students and teaches on Tobacco Control for the Masters in Public Health run by the Division of Epidemiology and Public Health. (nottingham.ac.uk)
  • Ferber SG, Makhoul IR The effect of skin-to-skin contact (kangaroo care) shortly after birth on the neurobehavioral responses of the term newborn: a randomized, controlled trial. (britishjournalofmidwifery.com)
  • While maternal and newborn care should be grounded in high quality evidence, the humanitarian response must not be stalled as randomized control trials are conducted and studies are peer-reviewed. (mhtf.org)
  • LILACS, MEDLINE y Biblioteca Virtual en Salud, utilizándose combinaciones entre los términos controlados newborn, COVID-19, SARS-CoV-2. (bvsalud.org)
  • Algarín C, Nelson CA, Peirano P, Westerlund A, Reyes S, Lozoff B (2013) Iron-deficiency anemia in infancy and poorer cognitive inhibitory control at age 10 years. (vitamindwiki.com)
  • Postnatal smoke exposure increases the respiratory complications in infancy and childhood. (who.int)
  • Enteral nutrition with unfortified human milk during the first 2 postnatal weeks often leads to cumulative protein and energy deficits among preterm infants. (aap.org)
  • Partial enteral nutrition with unfortified human milk during the first 2 postnatal weeks can be insufficient to prevent cumulative nutritional deficits in infants born extremely preterm (28 weeks of gestation or less). (aap.org)
  • The postnatal period has unique physiological and psychological aspects such as fatigue, interrupted sleeping and the adoption of new routines such as breastfeeding. (biomedcentral.com)
  • These unique aspects may affect responses on self-report measures which include items that are not appropriate for the postnatal period [ 10 ]. (biomedcentral.com)
  • We picked the hospital setting because almost all parents are in the hospital for some period of time following the birth of an infant and already routinely receive education about healthy baby topics. (medicalresearch.com)
  • Children who devel- a better understanding of the disease and, consequently, oped the disease in the postnatal period may show abnor- improve treatment and preventive strategies to manage the malities in pulmonary function5. (bvsalud.org)
  • We plan to assess the feasibility of evaluating metformin versus placebo in minimising the risk of dysglycaemia including type 2 diabetes after delivery in postnatal women with a history of gestational diabetes through a randomised trial. (birmingham.ac.uk)
  • We could not assess this review question due to lack of eligible trials. (cochrane.org)
  • Study design: Randomized control trial Objectives: To assess the added effect of core strengthening on performance within young competitive swimmers. (researchgate.net)
  • Since then, the literature on the topic has expanded, and more information is now available on neonatal as well as long-term consequences of both inadequate and excessive GWG during pregnancy. (nationalacademies.org)
  • We found no evidence from randomized controlled trials that levothyroxine plus liothyronine improves symptoms more than levothyroxine alone. (aafp.org)
  • 2019). Perineal massage and training reduce perineal trauma in pregnant women older than 35 years: a randomized controlled trial. (evidencebasedbirth.com)
  • Singleton pregnant women without incontinence before pregnancy who were aged ≥18 years and between 24 and 28 weeks of gestation were recruited from a tertiary public hospital in China and were randomly allocated (1:1) to either an experimental group (n=63) or a control group (n=63). (jmir.org)
  • Building on these findings, the POP-HT trial enrolled 220 pregnant women seen at Oxford University Hospitals in the UK who were age 18 years or older, had either gestational hypertension or preeclampsia, and still required antihypertensives when they were being discharged from hospital after giving birth. (medscape.com)
  • The sample size, determined using power analysis, included 105 pregnant adolescents (experimental group n =50, control group n =55). (rrh.org.au)
  • These individuals have postnatal onset with signs of hyperandrogenism. (clinicalgenome.org)
  • This is the first time a randomized clinical trial has clearly demonstrated that surgery before birth can improve the outcome for patients. (ucsf.edu)
  • A multitude of randomized clinical trials and other treatment studies have demonstrated that currently available therapeutic methods are 22%-94% effective in clearing external exophytic genital warts, and that recurrence rates are high (usually at least 25% within 3 months) with all modalities. (cdc.gov)
  • 1998. Genetic and environmental risk factors for asthma: a cotwin-control study. (cdc.gov)
  • The study was a block randomized control trial. (jmir.org)
  • The aims of this study were to explore how women experienced and made sense of the range of emotional distress states in the first postnatal year. (biomedcentral.com)
  • Rationale: We developed a standardized method, possible poor treatment response (PPTR), to help ascertain efficacy endpoints in Study S31/A5349 (NCT02410772), an open-label trial comparing two 4-month rifapentine-based regimens with a standard 6-month regimen for the treatment of pulmonary tuberculosis (TB). (cdc.gov)
  • This study was conducted using a pre-test-post-test randomized controlled design. (rrh.org.au)
  • We found no ongoing or completed randomized controlled studies. (cochrane.org)
  • We found no randomized controlled studies in our search. (cochrane.org)
  • Therapy with 5-fluorouracil cream has not been evaluated in controlled studies, frequently causes local irritation, and is not recommended for the treatment of genital warts. (cdc.gov)
  • Only with large, well-designed, and carefully controlled randomized studies can causal relationships be inferred with a high degree of confidence. (nationalacademies.org)
  • This trial identifies a potential need for a paradigm shift in the way women affected by hypertensive pregnancy are managed postnatally," Kitt said. (medscape.com)
  • All women spoke about the importance of their postnatal healthcare experiences in "Relationships in the healthcare system" . (biomedcentral.com)
  • Another issue is that self-report measures are validated against diagnostic criteria which may not be relevant to postnatal women. (biomedcentral.com)
  • This 7-in-1 daily nutritional powder supports postnatal healing and provides women with adequate nourishment to help boost their energy levels and immune system. (payitforwardfertility.org)
  • Results Fifteen trials with 7697 women were included. (bmj.com)
  • Smoking, Nicotine and Pregnancy (SNAP) trial - the world's largest trial of nicotine replacement therapy in pregnancy which recruited 1050 women and achieved 95% follow up rates. (nottingham.ac.uk)
  • Babies who undergo an operation to repair the birth defect spina bifida while still in the womb develop better and experience fewer neurologic complications than babies who have corrective surgery after birth, according to findings from a major multicenter trial led by UCSF researchers. (ucsf.edu)
  • Given the limited and diffuse understanding of the neurobiology of gestational eating patterns, the aim of this Review is to compile, integrate and discuss the research conducted on this topic in both experimental models and humans. (nature.com)
  • mental data from randomized controlled trials in humans, however, impedes efforts to determine how much of any observed association is causal. (nationalacademies.org)
  • Although the trial was stopped early due to financial concerns the authors demonstrated a 9% reduction in BPD using this strategy. (allthingsneonatal.com)
  • PPHN is characterised by failure to adapt to a functional postnatal circulation with a fall in pulmonary vascular resistance. (cochrane.org)
  • This trial was an enormous effort, and the entire team provided excellent care to the patients. (ucsf.edu)
  • Females are not virilized at birth (as in the classic form), though postnatal virilization can occur. (clinicalgenome.org)
  • to repair spina bifida while still in the womb develop better than babies who have corrective surgery after birth, according to findings from a UCSF-led trial. (ucsf.edu)
  • One randomized trial of laser therapy indicated efficacy of 43%, with recurrence among 95% of patients. (cdc.gov)
  • A randomized trial of surgical excision demonstrated efficacy of 93%, with recurrences among 29% of patients. (cdc.gov)
  • Efficacy of interferon injected directly into genital warts (intralesional therapy) during two randomized trials was 44%-61%, with recurrences among none to 67% of patients. (cdc.gov)
  • Author disclosure: Birte Nygaard declares that she has received payment from MERCK-Sorono during 2012 as invited speaker on two occasions, and for writing an overview on the topic of the use of L-T4 + L-T3 in the treatment of hypothyroidism. (aafp.org)
  • Randomised controlled trial of intravenous antibiotic treatment for cellulitis at home compared with hospital. (otago.ac.nz)
  • Go to Emphysema and Emergent Management of Chronic Obstructive Pulmonary Disease (COPD) for complete information on these topics. (medscape.com)
  • Trial findings will be published in a peer-reviewed journal, disseminated at conferences, through our Patient and Public Involvement advisory group (Katie's Team) and through social media platforms. (birmingham.ac.uk)
  • Important developments from trauma and emergency medicine around massive hemorrhage protocols are newly implemented for PPH, and the evidence base for PPH medical management is expanding, with clinical trials ongoing. (medscape.com)