• derivative
  • This chapter contains a tabular compilation of nuclear magnetic resonance data and UV-visible spectral data of thallium complex of porphyrin derivative C 110 H 90 Cl 2 N 8 Tl 2 . (springer.com)
  • 2. A porphyrin derivative according to claim 1 in the form of its pyridylium salt of the formula: ##STR29## in which R 2 is as defined in claim 1, R 7 is a C 1 to C 4 alkyl radical, A is an anion chosen from among Cl - , Br - or I - and M is a radioactive metal. (google.nl)
  • 10. A pharmaceutical composition, characterized in that it comprises, as active ingredient, a porphyrin derivative as defined in claim 1, in a pharmaceutically acceptable carrier. (google.nl)
  • 11. A pharmaceutical composition, characterized in that it comprises, as active ingredient, a porphyrin derivative according to claim 2 in a pharmaceutically acceptable carrier. (google.nl)
  • The present invention relates to an optionally metallized porphyrin derivative, which can be coupled to a biologically active molecule. (google.nl)
  • One of the first functional analogues of myoglobin was the ferrous derivative of the "picket fence porphyrin," which is structurally related to Fe(TPP), being derived via the condensation of 2-nitrobenzaldehyde and pyrrole. (wikipedia.org)
  • ligand
  • A schematic equation for these syntheses is shown: H2porphyrin + [MLn]2+ → M(porphyrinate)Ln−4 + 4 L + 2 H+ where M = metal ion and L = a ligand A porphyrin without a metal-ion in its cavity is a free base. (wikipedia.org)
  • Co(II)-porphyrin catalysts has good thermal and metal coordination stability resulting from the macrocyclic chelation effect of the aromatic ligand. (wikipedia.org)
  • Third, it has been well documented that the physical and chemical properties of a porphyrin complex of a given metal ion can be systematically tuned by introducing peripheral substituents with varied electronic, steric, and conformational environments on the aromatic ring structure of the porphyrin ligand. (wikipedia.org)
  • The initially formed C- and N-centered radicals can undergo common radical reactions such as radical addition and atom abstraction, but with effective control of reactivity and stereoselectivity by the porphyrin ligand environment. (wikipedia.org)
  • Uroporphyrins
  • No single vitamin of these three will inhibit the damaging effects of oxidized porphyrins, specifically uroporphyrins and coproporphyrins, but all three working together synergistically are capable of neutralizing their damaging effects. (wikipedia.org)

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  • Radicals
  • Due to their distinctive radical mechanisms that involve metal-stabilized radical intermediates, such as α-metalloalkyl radicals, α-metalloaminyl radicals, and α-metalloxyl radicals, the Co(II)-porphyrin-based catalysis system addresses some long-standing challenges in organic transformations. (wikipedia.org)
  • Stable metalloradicals such as Co-porphyrin catalysis activate diazo reagents and organic azides to generate C- and N-centered radicals, respectively, with nitrogen as the only byproduct in a controlled and catalytic manner. (wikipedia.org)
  • polymers
  • The polymerization, in the presence of a free-base porphyrin cored chain transfer agent (CTA-FBP), produced porphyrin star polymers with controlled molecular weights and narrow polydispersities for a number of monomers including N , N -dimethylacrylamide (DMA) and styrene (St). Well-defined amphiphilic star block copolymers, P-(PS-PDMA) 4 and P-(PDMA-PS) 4 (P: porphyrin), were also prepared and used for self-assembly studies. (hindawi.com)
  • Several porphyrin polymers have been synthesized [ 3 - 17 ]. (hindawi.com)
  • 14 ]. Despite these interesting discoveries, the self-assembly behaviour of porphyrin polymers is far from being understood and further research is required. (hindawi.com)
  • However, its use has been limited to metal ion (Zn(II) [ 16 ], Pd(II) [ 17 ]) coordinated porphyrin initiators and thus the production of metal complexed polymers. (hindawi.com)
  • Attempts to synthesize polymers containing free-base porphyrin using ATRP was unsuccessful, because Cu(II) (formed by the Cu(I) catalyst) will preferentially insert into the porphyrin core [ 14 , 16 ]. (hindawi.com)
  • Although metalloporphyrin polymers possess many interesting properties for applications, such as catalysis, light harvesting, oxygen transportation [ 3 - 17 ], and so on, other increasingly studied applications, such as sensors [ 18 ], prefer free-base porphyrin polymers. (hindawi.com)
  • pyrrole
  • A benzoporphyrin is a porphyrin with a benzene ring fused to one of the pyrrole units. (wikipedia.org)
  • Chlorins (2,3-dihydroporphyrin) are more reduced, contain more hydrogen than porphyrins, i.e. one pyrrole has been converted to a pyrroline. (wikipedia.org)
  • derivatives
  • The present invention relates to metallized porphyrin derivatives having the formula: ##STR1## wherein the R and M variables are as defined in the specification. (google.nl)
  • Said porphyrin derivatives having uses as antitumor agents, diagnostics agents, or in therapy. (google.nl)
  • More specifically, it relates to porphyrin derivatives usable in the pharmaceutical field, either as antitumour agents, or diagnostic agents, or in therapy, particularly when they incorporate a radioactive metal. (google.nl)
  • Some porphyrin derivatives follow Hückel's rule, but most do not. (wikipedia.org)
  • Molecules
  • They find that electron- acceptor molecules such as trinitrobenzene (TNB) form 1:1 adducts with the expanded porphyrins, which leads to changes in color and can produce columnar stacking and the formation of discotic mesophases. (sciencemag.org)
  • Deep understanding of the specific early relaxation mechanism and nuclear wavepacket motion occurring in this family of molecules is therefore fundamental for further comprehension of the role of porphyrins in nature and future application using porphyrin-based molecular devices. (epfl.ch)
  • oxygen
  • A very simple and efficient singlet-oxygen-mediated oxidative system that uses solar radiation, molecular oxygen, and Merrifield-supported porphyrins is presented. (wiley.com)
  • The damaging effects of porphyrins interacting with iron, absorbing photons to then emit reactive oxygen species is the mechanism of action that results in the itchy, painful blisters that are common with PCT. (wikipedia.org)
  • aromatic
  • With a total of 26 π-electrons, of which 18 π-electrons form a planar, continuous cycle, the porphyrin ring structure is often described as aromatic. (wikipedia.org)
  • Centers
  • These porphyrin tapes can chelate different metal centers, changing their optical and electronic properties. (epfl.ch)
  • electron
  • Density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations suggest that the higher J sc values of Zn-based porphyrin sensitizers result from the favorable electron injection from the LUMO at higher energy levels. (mdpi.com)
  • Spectral
  • Wavepacket dynamics of free-base porphyrins are discussed in the fourth chapter, where the phase and spectral intensity of the vibrational modes were extracted using Fourier transform spectroscopy. (epfl.ch)
  • metal
  • Quite interestingly, the porphyrin 1 showed that it can function as a single optical chemical sensor and/or metal ion receptor capable of detecting two or more toxic metal ions, particularly Hg 2+ , Pb 2+ , and Cd 2+ ions coexisting in a water sample. (hindawi.com)
  • Porphyrin 1 in an aqueous solution provides a unique UV-vis sensing system for the determination of Cd 2+ in the presence of larger metal ions such as Hg 2+ , or Pb 2+ . (hindawi.com)
  • Similarly, porphyrins, which feature 16-membered central rings, form in the absence of metal templates. (wikipedia.org)
  • acid
  • In non-photosynthetic eukaryotes such as animals, insects, fungi, and protozoa, as well as the α-proteobacteria group of bacteria, the committed step for porphyrin biosynthesis is the formation of δ-aminolevulinic acid (δ-ALA, 5-ALA or dALA) by the reaction of the amino acid glycine with succinyl-CoA from the citric acid cycle. (wikipedia.org)
  • sensors
  • The photophysics of porphyrins has been widely investigated because of their importance in biology and their relevance in a wide range of applications such as light harvesting applications, molecular electronics, and gas sensors. (epfl.ch)
  • biological
  • Porphyrin containing biological systems, where the dye usually works in aggregated structures, offer insights to these possibilities. (hindawi.com)
  • Visual phototransduction Woodward's rules Chromatophore Pigment Photophore Fluorophore Litmus Biological pigment IUPAC Gold Book Chromophore Gouterman, M. (1978) Optical spectra and electronic structure of porphyrins and related rings. (wikipedia.org)
  • free-base
  • In the third chapter we discuss the impulsive heating of free-base porphyrins and the electronic and vibrational relaxation dynamics upon photo-excitation. (epfl.ch)