• variation
  • Reciprocally, the pattern of variation along the alignment carries information on the underlying genealogies, and this variation enables the estimation of population parameters. (genetics.org)
  • Rather than one or two domestication events leading to the extant baker's yeasts, the population structure of S. cerevisiae consists of a few well-defined geographically isolated lineages and many different mosaics of these lineages, supporting the idea that human influence provided the opportunity for cross-breeding and production of new combinations of pre-existing variation. (pubmedcentralcanada.ca)
  • and (3) determining the frequencies of the selected alleles in natural population for identification of the adaptive variation pattern in the heterogeneous environment. (deepdyve.com)
  • The range of natural variation among these characters that may have existed in ancient wolf populations, and the time it took for these traits to appear in dogs, are unknown. (wikipedia.org)
  • Natural selection will only cause evolution if there is enough genetic variation in a population. (wikipedia.org)
  • The Hardy-Weinberg principle provides the solution to how variation is maintained in a population with Mendelian inheritance. (wikipedia.org)
  • In a series of papers starting in 1918 and culminating in his 1930 book The Genetical Theory of Natural Selection, Fisher showed that the continuous variation measured by the biometricians could be produced by the combined action of many discrete genes, and that natural selection could change allele frequencies in a population, resulting in evolution. (wikipedia.org)
  • evolution
  • There have been lots of really nice Klebs genomics papers out in the last 18 months or so, examining the evolution of the ST258 clone that carries the KPC gene ( K. pneumoniae carbapaenemase) and is wreaking havoc in hospitals all over the place (including recently in Melbourne), and also several hospital-based studies tracking transmission and evolution of local drug-resistant outbreaks. (holtlab.net)
  • analyses
  • Moore et al conducted a study in 2014 in which a group of Atlantic Salmon populations which were previously analyzed with traditional population genetic analyses (microsatellites, SNP-array genotyping, BayeScan (which uses the Dirichlet-multinomial distribution)) to place them into defined conservational units. (wikipedia.org)
  • distinct
  • In 2014 his team showed that all paleoeskimos in the New World representing several distinct cultures all belonged to the same population as the Saqqaq man and that they lived in genetic isolation from Native Americans for almost 5,000 years before they died out some 700 years ago. (wikipedia.org)
  • At least four genetically and phenotypically distinct populations of Saccharomyces paradoxus have been identified, corresponding to main geographical divisions: Europe (including West Siberia), Far East Asia (Japan, Eastern Siberia), North America (North American East and West coasts, Great Lakes region) and North-East America (Gaspé Peninsula, Saint Lawrence Valley and Appalaches), respectively. (wikipedia.org)
  • research
  • March 9, 2011 - See Notice NOT-HG-11-016 Notice to Encourage Use of Research Project Grant (Parent R01) PA-10-067 and NIH Exploratory Developmental Research Grant Program (Parent R21) PA-10-069 to Support Technology and Methods Development for Genomics, Population Genomics and ELSI Research. (nih.gov)
  • Collecting and analyzing human genetic data in population-based research can help us interpret variations in health and disease among people and across populations. (cdc.gov)
  • admixture
  • 2015), the Andronovo culture and the preceding Sintashta culture are partially derived from the Corded Ware culture, given the higher proportion of ancestry matching the earlier farmers of Europe, similar to the admixture found in the genomes of the Corded Ware population. (wikipedia.org)
  • 2015), autosomic tests indicate that the Yamnaya-people were the result of admixture between two different hunter-gatherer populations: distinctive "Eastern European hunter-gatherers" with high affinity to the Mal'ta-Buret' culture or other, closely related people from Siberia and a population of "Caucasus hunter-gatherers" who probably arrived from somewhere in the Near East, probably the Caucasus. (wikipedia.org)
  • today's
  • 2015), "Eastern European hunter-gatherers" who inhabited today's Russia were a distinctive population of hunter-gatherers with high affinity to a ~24,000-year-old Siberian from Mal'ta-Buret' culture, or other, closely related people from Siberia. (wikipedia.org)
  • approach
  • In addition, instructors provided general advice about how to approach population genomics data analysis and how to build a career in science. (nih.gov)
  • Here, we use a population genomics approach to examine striking parallel morphological divergences of parapatric stream-lake ecotypes of threespine stickleback fish in three watersheds on the Haida Gwaii archipelago, western Canada. (royalsocietypublishing.org)
  • adaptive
  • In 1932 Wright introduced the concept of an adaptive landscape and argued that genetic drift and inbreeding could drive a small, isolated sub-population away from an adaptive peak, allowing natural selection to drive it towards different adaptive peaks. (wikipedia.org)
  • different
  • The two lineages would have been passed to and survived within the ancestral population (ancestral polymorphism), potentially having a genealogy different from the phylogeny. (genetics.org)
  • This was the first genetic evidence for cultural change happening in isolation through the spread of ideas within a population rather than through meetings between different groups of peoples as seen e.g. during the European Neolithisation. (wikipedia.org)
  • researchers
  • P3G (Public Population Project in Genomics and Society) is a not-for-profit international consortium dedicated to facilitating collaboration between researchers and biobanks working in the area of human population genomics. (wikipedia.org)
  • Training - provides researchers in the biobanking field with pertinent and up-to-date training opportunities Catalogs - currently provide information on large population-based biobanks. (wikipedia.org)
  • SMGF also outsourced all of its laboratory work to Sorenson Genomics, freeing researchers to create a publicly available online repository. (wikipedia.org)
  • Wolf
  • This indicates that an extant wolf population ancestral to dogs has not been found, and is presumed that the wolves immediately ancestral to dogs are extinct. (wikipedia.org)
  • steppes
  • Mezhovskaya culture reflects the further stages of development Ugric community in active contact with the Indo-Iranian population of the Ural steppes. (wikipedia.org)
  • processes
  • While such data cannot be used to study contemporary populations, they contain information about ancestral population processes, particularly when speciation events are sufficiently close in time that incomplete lineage sorting (ILS) occurs. (genetics.org)
  • speciation
  • The amount of ILS depends on population parameters such as the ancestral effective population sizes and the recombination rate, but also on the number of generations between speciation events. (genetics.org)
  • The theory of coalescence allows us to predict quantities like the proportions of sites in each type of genealogy according to ancestral effective population sizes, speciation times, and recombination rates. (genetics.org)
  • genes
  • The American biologist Sewall Wright, who had a background in animal breeding experiments, focused on combinations of interacting genes, and the effects of inbreeding on small, relatively isolated populations that exhibited genetic drift. (wikipedia.org)
  • group
  • Richard Michael Durbin, FRS, born (1960-12-30) 30 December 1960 (age 57), is a British computational biologist, Senior Group Leader at the Wellcome Trust Sanger Institute and an Honorary Professor of Computational genomics at the University of Cambridge. (wikipedia.org)
  • Zealand
  • Some strains from the European population are found in North America and New Zealand and likely result from recent colonization events. (wikipedia.org)
  • Andronovo
  • The ancestors of Mezhovskaya culture's were the population of Cherkaskul culture with the participation of the population of Tobol taiga with traditions and cultures of the ceramics steppe zone of the Ural and Kazakhstan (Andronovo culture) ), especially Sargarino-Alexis culture. (wikipedia.org)
  • The mixed population: Indo-European (Andronovo culture) and Ugric (Cherkaskul culture) tribes. (wikipedia.org)
  • human
  • Using two large population samples of Streptococcus pneumoniae, we demonstrate the ability of SuperDCA to make additional significant biological findings about this major human pathogen. (hiit.fi)